Clinical Trials on Antibiotic Toxicity

Total 1036 results

University of Oxford
London School of Hygiene and Tropical Medicine; University College, London; KEMRI-Wellcome... and other collaborators

Unknown

First Line Antimicrobials in Children With Complicated Severe Acute Malnutrition (FLACSAM)

Antibiotic Resistance | Malnutrition Severe | Antibiotic Toxicity

Kenya, Uganda
TTY Biopharm

Completed

A Pharmacokinetic Study of Polymyxin B in Healthy Subjects and Subjects With Renal Insufficiency

Antibiotic Toxicity

Taiwan
Central Hospital, Nancy, France

Completed

Target Attainment of TDM-guided Infusion of Piperacillin/Tazobactam and Cefepim in Critically Ill Patients (DOSATB)

Sepsis | Critical Illness | Septic Shock | Antibiotic Toxicity

France
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
Jessa Hospital

Completed

Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB) (Prophylaxis001)

Bladder Cancer | Antibiotic-associated Diarrhea | Antibiotic Resistant Infection | Antibiotic Resistant Strain | Antibiotic Toxicity | Prostate Hyperplasia | Urosepsis

Belgium
Central Hospital, Nancy, France
PAPE Elise

Not yet recruiting

Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis (DIFFUPERPED)

Appendicitis | Peritonitis | Children, Only | Antibiotic Toxicity
Institute for Clinical Evaluative Sciences
Canadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaborators

Completed

Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID -LTC) - Phase 2 (FIRST AID-LTC)

Antibiotic Initiation | Antibiotic Duration

Canada
Institute for Clinical Evaluative Sciences
Canadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaborators

Completed

Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID-LTC)

Antibiotic Initiation | Antibiotic Duration

Canada
Seed Health

Completed

Metagenomic and Metabolomic Reconstitution of Gut Microbiota After Broad Spectrum Antibiotic Therapy

Antibiotic-associated Diarrhea | Antibiotic Side Effect | Antibiotic-induced Dysbiosis | Antibiotic-induced Epithelial Barrier Disintegrity

Canada
University Hospital, Bordeaux
University of Bordeaux

Recruiting

Antibiotic Prescription Relevance Indicators: Calculation From Electronic Health Records (ARIPPA)

Surgery | Antibiotic

France
Oxford University Clinical Research Unit, Vietnam
National Institute of Hygiene and Epidemiology, Vietnam

Recruiting

Generating Collective Solutions to Reduce Unnecessary Antibiotic Use in Vietnam

Antibiotic Use

Vietnam
Centre Hospitalier Universitaire de Saint Etienne

Not yet recruiting

Antibiotic Prescribing Behavior Among French Intensivist: Construction and Validation of a Questionnaire

Antibiotic Reaction

France
Nantes University Hospital

Completed

Impact on Antibiotic Prescriptions of a Bundle Intervention Conducted by Medical Representatives in General Practitioner Facilities, Based on Operational Demonstration of an Internet Decision Support Tool: Antibioclic (ACTION)

Antibiotic Resistance

France
Central Hospital, Nancy, France
University of Lorraine

Completed

Impact of a Communication Toolkit on Antibiotic Prescribed by General Practitioners: a Randomised Trial

Antibiotic Prescription

France
University Hospital, Akershus
Oslo University Hospital; Helse Stavanger HF; Sorlandet Hospital HF; Sykehuset... and other collaborators

Terminated

Fecal ESBL Resurgence During Antibiotic Treatment

Antibiotic Drug Resistance
University Hospital Tuebingen
University Hospital of Cologne

Completed

Amplification and Selection of Antimicrobial Resistance in the Intestine II (ASARI II)

Antibiotic Selection Pressure

Germany
Poitiers University Hospital

Completed

Study of Repeated Cefoxitin Administration in Major Abdominal Surgery Using a Microdialysis Technique (PROPHYLOXITINE)

Antibiotic Prophylaxis Surgery

France
Helperby Therapeutics Ltd
Richmond Pharmacology Limited

Completed

Effect of Minocycline & Amoxicillin on Antibiotic Resistant Bacteria and Indigenous Microbiotas (ANTIRESDEV)

Antibiotic Resistant Bacteria

United Kingdom
Sheba Medical Center
Maccabi Healthcare Services, Israel

Completed

Israeli Judicious Antibiotic Prescription Study (IJAP)

Antibiotic Use | Carriage of Antibiotic Resistant Pathogens
Uppsala University
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden; University... and other collaborators

Recruiting

Use of New Antibiotics in Sweden

Multi-antibiotic Resistance

Sweden
Federal Research Institute of Pediatric Hematology...

Not yet recruiting

Fecal Microbiome Transplantation (FMT) in Pediatric Patients Colonized With Antibiotic-resistant Pathogens Before Hematopoietic Stem Cell Transplantation (HSCT) (FMT-HSCT)

Antibiotic Resistant Strain

Russian Federation
University of British Columbia

Recruiting

Fecal Transplant for MDRO Decolonization

Multi-antibiotic Resistance

Canada
University of Fribourg

Recruiting

Antibiotic-induced Disruption of the Microbiota (ABERRANT)

Microbiota | Antibiotic Disruption

Switzerland
H. Tolga Çelik

Completed

The Effect of Probiotic Supplement on Urinary D-lactic Acid Level in Newborns

Antibiotic Side Effect

Turkey
Tel-Aviv Sourasky Medical Center

Unknown

Preventive Antibiotic Serum Levels During Caesarean Section

Blood Antibiotic Levels
Milton S. Hershey Medical Center

Completed

Probiotics in Primary Care

Antibiotic Side Effect

United States
University of Novi Sad

Active, not recruiting

Complications After Lower Third Molar Surgery

Postoperative Complications | Infection, Bacterial | Antibiotic Side Effect | Antibiotic Resistant Infection | Antibiotic Resistant Strain | Antibiotic Reaction | Infection, Laboratory

Serbia
Qianfoshan Hospital

Completed

Risk Factors and Machine Learning Model for Beta-Lactam Drugs Related Acute Kidney Injury

Acute Kidney Injury | Beta-Lactam Antibiotic Toxicity (Diagnosis)

China
Karolinska University Hospital

Recruiting

Pharmacokinetics of Piperacillin and Meropenem in ICU Patients

Antibiotic Pharmacokinetics

Sweden
Danisco
KGK Science Inc.

Completed

Probiotic Product in Healthy Adults Undergoing Antibiotic Treatment

Antibiotic Therapy

Canada
Makerere University
Mbarara University of Science and Technology; Swedish International Development...

Not yet recruiting

Using the ATC/DDD to Monitor Antibiotic Use at Lower Primary Care Facilities in Southwestern Uganda

ATC/DDD | Antibiotic Utilization

Uganda
University of Iowa
National Institutes of Health (NIH); National Center for Advancing Translational...

Completed

Mobile-health Approach to Gather Clinical Information From Patients Following Hospital Discharge

Outpatient Parenteral Antibiotic Therapy

United States
Milton S. Hershey Medical Center

Completed

Diminish Chemotherapy Related Side Effects Through Patient Education (D-CRSE)

Chemotherapy Effect | Chemotherapeutic Toxicity | Chemotherapeutic Agent Toxicity

United States
Pharmbio Korea Co., Ltd.

Completed

Effect of Probiotic Lactobacilli (Lacidofil Cap®) for the Prevention of Antibiotic-Associated Diarrhea

Pulmonary Infection | Antibiotics Associated Colitis

Korea, Republic of
Cairo University

Not yet recruiting

The Pattern of Antibiotic Prescription for Children Among a Group of Pediatric Dentists.

Antibiotic Resistant Strain

Egypt
Cultech Ltd
Comac Medical

Completed

The Impact of Probiotic Supplementation on Antibiotic Induced Changes in Gastrointestinal Function and/or Faecal Microbiota Composition (FANTIB)

Antibiotic Side Effect

Bulgaria
University of British Columbia

Terminated

Fecal Transplant for MDR Pathogen Decolonization

Multi-antibiotic Resistance

Canada
Tel-Aviv Sourasky Medical Center
Weizmann Institute of Science

Unknown

Endoscopic Assessment and Prediction of Microbiome-modifying Interventions (microbiome)

Antibiotic Side Effect | Gut Microbiome

Israel
UNC Lineberger Comprehensive Cancer Center

Recruiting

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

Toxicity | Radiation Toxicity

United States
University of Wisconsin, Madison
University of Pittsburgh

Completed

Building a Novel Antibiotic Stewardship Intervention for Nursing Homes (OASIS)

Antibiotics
University Hospital, Bordeaux

Recruiting

Pharmacokinetics and Safety of Antimicrobial Agents Administered by Subcutaneous Route in Patients AGEd Over 65 Years (PhASAge)

Older People | Antimicrobials | Subcutaneous Injection | Antibiotic

France
Landspitali University Hospital

Active, not recruiting

The Effects of Antibiotic Exposure in Early Infancy on Vaccine Responses

Antibiotic Treatment | Immune Responses

Iceland
The University of Texas Health Science Center at...

Completed

Rapid PCR to Guide Antibiotic Therapy at the Time of Prostate Biopsy

Prostate Biopsy | Antibiotic Therapy

United States
Misr International University

Completed

Antibiotic Usage and Resistance; Knowledge and Practices Before and After Educational Sessions

Antibiotics

Egypt
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Dynamics of AMR Spread, Persistence and Evolution Between Humans, Animals and Their Environment (Dyaspeo)

Antibiotic Resistant Strain | Transmission, Close-Contact

France
Cairo University

Completed

Prescription Pattern and Awareness About Antibiotic Prophylaxis and Resistance

Antibiotic Prescription

Egypt
Takeda

Completed

Case Control Study of Pharmacogenomic Factors Associated With Hepatocellular Injury Following Exposure to Lapaquistat Acetate

Toxicity

United States, Argentina, Poland, South Africa, Russian Federation, Netherlands, Chile, Canada, Germany, Latvia, Finland, United Kingdom, Czech Republic, Slovakia
Institut Claudius Regaud

Suspended

Kidney Damage in Patients Receiving Cisplatin and Ifosfamide for Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Chemotherapeutic Agent Toxicity | Renal Toxicity

France
Cairo University

Not yet recruiting

Antibiotics, Antibiotic Resistance, and Prescribing Practices Among Periodontists: Cross Sectional KAP Study

Periodontitis | Antibiotic Resistance | Antibiotic Use
N&N Pharmaceuticals Inc.

Unknown

Evaluating the Safety and Plasma Levels of N-Methanocarbathymidine (N-MCT) in Normal Patients

Toxicity

United States

Clinical Trials on Antibiotic Toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Germany

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations