Clinical Trials on Antipsychotics

Total 43 results

University Hospital, Caen

Unknown

Use of Antipsychotics in Palliative Care (NEUROPAL) (NEUROPAL)

Antipsychotics in Palliative Care
Janssen Research & Development, LLC

Completed

Whole Blood and Plasma Sample Collection for the Development of Antipsychotic Immunoassays From Participants Taking Aripiprazole, Olanzapine, Paliperidone, or Risperidone

Immunoassay | Antipsychotic

Belgium
Wayne State University

Withdrawn

Beta-carotene and Oxidative Stress in Pediatric Second Generation Antipsychotic Use

Pediatric Population on Second Generation Antipsychotics
Women's College Hospital
Ontario Ministry of Health and Long Term Care; Ontario Medical Association; Health... and other collaborators

Completed

Pragmatic Cluster Trial for Nursing Home Antipsychotic Prescribing

Adverse Effect of Other Antipsychotics and Neuroleptics
Seoul National University Hospital

Completed

Change in Brain Metabolism and Cognitive Function by Aripiprazole

Cognition | Antipsychotics | Brain Metabolism | Dopamine Receptor Occupancy

Korea, Republic of
Brigham and Women's Hospital
National Institute on Aging (NIA); Ideas42

Completed

Novel Application of Simulation for Providers to Overcome Decisional Gaps in High-risk Prescribing

Medication Administered in Error | Antipsychotics and Neuroleptics Toxicity

United States
Dr Rabia Arshad

Completed

Synergistic Effect of Vitamin E & D in Reducing Risk of Effects Associated With Atypical Anti-psychotics

Antipsychotics and Neuroleptics Toxicity

Pakistan
Psychiatric Centre Rigshospitalet
AstraZeneca

Terminated

KvaliMed - a Quality Project With Focus on Patients in Antipsychotic Treatment (KvaliMed)

Medical Treatment | Antipsychotic Treatment | Quality Assurance

Denmark
Icahn School of Medicine at Mount Sinai
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Maternal And Infant Antipsychotic Study (MAIA)

Pregnancy | Antipsychotics
Northwell Health

Completed

Acute D2 Receptor Blockade Induced Neuronal Network Changes in Human Volunteers

Imaging of the Brain and Antipsychotics | Neuronal Network Changes

United States
University of British Columbia
Icahn School of Medicine at Mount Sinai; Vancouver Coastal Health

Unknown

Adverse Events and Genomics in Schizophrenia (AEGIS)

Adverse Effect of Other Antipsychotics and Neuroleptics

Canada
Taipei Medical University Hospital
Department of Health, Executive Yuan, R.O.C. (Taiwan); National Science Council...

Completed

The Study of Atypical Antipsychotics-induced Metabolic Disturbances

Schizophrenia | Antipsychotics

Taiwan
Ludwig-Maximilians - University of Munich
University Hospital Heidelberg; University of Witten/Herdecke; University Hospital... and other collaborators

Recruiting

Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy (PARTNER)

Antipsychotic Agents | Antidepressive Agents | Analgesics, Opioid | Deprescriptions | Hypnotics and Sedatives | Cholinergic Antagonists

Germany
Instituto Nacional de Psiquiatría Dr. Ramón de...

Completed

Metabolic Effects of Melatonin in Patients Treated With Second Generation Antipsychotics

Second Generation Antipsychotic Induced Metabolic Adverse Effects

Mexico
University of Massachusetts, Worcester
Agency for Healthcare Research and Quality (AHRQ); Omnicare Clinical Research; Qualidi...

Completed

iADAPT: Off Label Use of Antipsychotics in the Nursing Home

Off-label Use of Atypical Antipsychotic Drugs

United States
Centre hospitalier de Ville-Evrard, France

Recruiting

Assessment of Pain During Intramuscular Injection Delay in Adult Psychiatry (evadoulim)

Delayed Antipsychotic Treatment, Pharmacological Factors and Individual Factors

France
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

MAintain the Efficacy and Safety in Treatment of Schizophrenia After Switching to Long-acTing Injectable aRipiprazole From Oral Atypical Antipsychotics (MAESTRO)

Schizophrenia | Antipsychotics | Long-Acting Injection | LAI | Aripiprazole

Korea, Republic of
Cwm Taf University Health Board (NHS)

Unknown

Clozapine Induced Weight Gain

Weight Gain | Pharmacogenetics | Antipsychotic Agents

United Kingdom
Wayne State University

Completed

Molecular Mechanisms of Antipsychotic-induced Insulin Resistance

Insulin Resistance | Adverse Effect of Other Antipsychotics and Neuroleptics

United States
Institute of Mental Health, Singapore

Completed

Aripiprazole as an Adjunct to Atypical Antipsychotics for Weight Reduction and Improvement in Metabolic Profile

Antipsychotics Weight Gain

Singapore
Corcept Therapeutics

Completed

The Effect of CORT118335 on Olanzapine-Induced Weight Gain

Antipsychotic-induced Weight Gain

United Kingdom
Wayne State University

Completed

Pharmacoepigenetics of Bipolar Disorder Treatment

Bipolar Disorder | Antipsychotic Agents

United States
Centre for Addiction and Mental Health

Recruiting

Effects of Antipsychotics on Brain Insulin Action in Females

Insulin Resistance | Type 2 Diabetes | Menstrual Cycle | Antipsychotics

Canada
Alexza Pharmaceuticals, Inc.
Atlanta Center for Medical Research

Completed

Staccato Loxapine Multidose PK

Volunteers on Chronic, Stable Antipsychotic Regimens

United States
Tanta University

Not yet recruiting

Empagliflozin Addition in Modulating Metabolic Disturbances Associated With Olanzapine in Schizophrenia Patients

Sodium-glucose Transport Protein Two Inhibitor (SGLT2),Metabolic Deficits Caused by Antipsychotics
Assiut University

Not yet recruiting

Pattern of Acute Antipsychotic Drug- Toxicity in Children

Antipsychotic Drug- Toxicity
University of Cincinnati
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

SGA-induced Metabolic Syndrome in Bipolar Youth

Bipolar Youth Treated With Second-generation Antipsychotics

United States
Janssen Korea, Ltd., Korea

Completed

A Study to Evaluate Treatment Adherence in Schizophrenia With Long Acting Risperidone Microspheres (e-STAR)

Mental Disorders | Schizophrenia | Tranquilizing Agents | Therapeutic Uses | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents
Centre for Addiction and Mental Health

Recruiting

"Extended" (Alternate Day) Antipsychotic Dosing

Drug Therapy | Schizophrenia and Related Disorders | Antipsychotic Agents | Drug Administration Schedule

Canada
Herlev and Gentofte Hospital
Odense University Hospital; Zealand University Hospital; Aarhus University Hospital and other collaborators

Recruiting

Monitoring of Arrhythmias in Patients Treated With Antipsychotics (MAPP)

Death, Sudden, Cardiac | Arrythmia | Antipsychotics and Neuroleptics Toxicity

Denmark
Northwell Health

Terminated

1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain

High Risk MC4R Genotype | Low Risk MC4R Genotype | One Week or Less Antipsychotic Lifetime Exposure

United States
Massachusetts General Hospital
Alkermes, Inc.; Otsuka America Pharmaceutical; Eisai Inc.; Janssen Pharmaceuticals and other collaborators

Recruiting

National Pregnancy Registry for Atypical Antipsychotics

Depression | Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Use of Atypical Antipsychotics During Pregnancy

United States
University of North Carolina, Chapel Hill
Foundation of Hope, North Carolina

Completed

Randomized Controlled Trial of Pyridoxine for Tardive Dyskinesia

Tardive Dyskinesia | Antipsychotic Agents

United States
Corcept Therapeutics

Completed

Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Obese Adult Patients With Schizophrenia While Taking Antipsychotic Medications (GRATITUDE II)

Antipsychotic-induced Weight Gain (AIWG)

United States
University of Liverpool
Obafemi Awolowo University Teaching Hospital; Federal Medical Centre, Makurdi; Federal Neuropsychiatric Hospital, Yaba and other collaborators

Recruiting

Long-acting Injectable Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum (LAMP)

Schizophrenia | Pregnancy | Mania | Psychosis | Breastfeeding | Antipsychotic Agents | Drug Exposure in Utero | Drug Exposure Via Breast Milk

Nigeria
Corcept Therapeutics

Completed

Study to Evaluate the Effects of a Cytochrome P450 2C19 Inhibitor on the Pharmacokinetics of Miricorilant

Non-alcoholic Steatohepatitis (NASH) | Antipsychotic Induced Weight Gain

United States
Corcept Therapeutics

Completed

This Phase 2, Double Blind, Placebo-controlled, Randomized Study is to Assess the Safety and Efficacy of Miricorilant in Obese Adult With Schizophrenia or Bipolar Disorder Treated With Antipsychotic Medications.

Antipsychotic-induced Weight Gain (AIWG)

United States
Luye Pharma Group Ltd.

Completed

Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Schizophrenia Spectrum and Other Psychotic Disorders | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Neurotransmitter Agents | Central...

United States
Luye Pharma Group Ltd.

Completed

Relative Bioavailability of LY03010 Compared to Listed Drug

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Central Nervous System Depressants | Neurotransmitter Agents | Schizophrenia Spectrum

United States
Ulla Schierup Nielsen
Central Denmark Region; Mental Health Services in the Capital Region, Denmark; North Denmark Region

Recruiting

PROSA: Prolactin, Sex Hormones, Growth and Metabolic Biomarkers in Children and Adolescents on Antipsychotics (PROSA)

Metabolic Syndrome | Growth Disorders | Hyperprolactinemia | Puberty Disorders | Antipsychotics and Neuroleptics Toxicity

Denmark
Merck Sharp & Dohme LLC

Terminated

Study of Preladenant for the Treatment of Neuroleptic Induced Akathisia (Study P05145)

Movement Disorders | Antipsychotic Agents | Akathisia, Drug-Induced
Taichung Veterans General Hospital

Completed

Adjunctive Use of Fute (Flupentixol) in Multi-acting Receptor-targeted Antipsychotics Treated Schizophrenia Patients

Central Nervous System Diseases | Metabolic Syndrome | Schizophrenia; Psychosis | Antipsychotic Agents | Olanzapine | Flupentixol | Clinical Therapy | Quetiapine

Taiwan
Ohio State University

Not yet recruiting

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Movement Disorders | Aging | Behavior | Dementia With Lewy Bodies | Emergency Psychiatric | Cognition Disorder | Antipsychotics and Neuroleptics Toxicity | Alteration in Mental Status

Clinical Trials on Antipsychotics

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