Clinical Trials on Avanfil ADME

Total 43 results

VIVUS LLC

Completed

A Pharmacokinetic Study of Avanfil in Healthy Young Male Subjects

Avanfil ADME | Semen Exposure | Sperm Function

United States
The Institutes for Pharmaceutical Discovery, LLC
Covance; Mars, Inc.

Completed

Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin in Humans

ADME

United States
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Mass Balance of 14C-Napabucasin in Healthy Adult Male Subjects

Healthy | ADME

United States
Aristea Therapeutics, Inc.

Completed

A Study of the ADME of [14C]RIST4721 in Healthy Male Subjects

Healthy | ADME

United Kingdom
Future University in Egypt

Not yet recruiting

Clinical Performance of High Viscosity Bioactive Injectable Composite in Deep Marginal Elevation (Randomized)

DME | Dental | Deep Margin Elevation
Shahid Beheshti University of Medical Sciences

Completed

Short-term Additive Effect of Topical Ketorolac on the Management of Diabetic Macular Edema With Intravitreal Bevacizumab

DME

Iran, Islamic Republic of
EnnovaBio

Recruiting

A Phase 2 Study to Evaluate the Efficacy and Safety of ENN0403 in Subjects with DME

Diabetic Macular Edema (DME)

China
Alimera Sciences

Completed

Phase 4 IOP Signals Associated With ILUVIEN® (PALADIN)

Diabetic Macular Edema (DME)

United States
Hadassah Medical Organization
Bayer

Completed

Multicenter Study to Evaluate the Efficacy of Treat and Extend Regimen of Aflibercept (EYLEA) as a Second Line Treatment for Diabetic Macular Edema

Diabetic Macular Edema (DME)
Second Affiliated Hospital, School of Medicine,...
Ningbo Eye Hospital; Jiaxing Hospital of T.C.M

Active, not recruiting

Early Combined Use of Dexamethasone Intravitreal Implant and Anti-VEGF in the Treatment of DME.

Diabetic Macular Edema (DME)

China
Celltrion

Completed

Study to Compare Efficacy and Safety of CT-P42 in Comparison With Eylea in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)

Slovakia
YD Global Life Science Co., Ltd.

Unknown

The Study to YD312 Tablet in Patients With Diabetic Macular Edema

Diabetic Macular Edema(DME)

United States, Korea, Republic of
Aerpio Therapeutics

Completed

Safety and Pilot Efficacy of AKB-9778 in Subjects With Diabetic Macular Edema

Diabetic Macular Edema (DME)

United States
EyeBiotech Ltd.

Recruiting

A Study of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME (BAROLO)

Diabetic Macular Edema (DME)

United States, Puerto Rico, Colombia, Argentina, Brazil
Kyowa Kirin Co., Ltd.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)

Japan, Korea, Republic of, Australia, United States
EyeBiotech Ltd.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME (BRUNELLO)

Diabetic Macular Edema (DME)

United States, Spain, Australia, Puerto Rico, Argentina, Austria, Colombia, Croatia, Czechia, France, Germany, Hungary, Israel, Italy, Latvia, Poland, Portugal, Slovakia, Turkey, United Kingdom
Khyber Teaching Hospital

Completed

Comparison of Intravitreal Bevacizumab Injection with Combination of Suprachoroidal Triamcinolone Acetonide Along with Intravitreal Bevacizumab Injection in the Treatment of Diabetic Macular Edema in Pseudophakic Patients

Diabetic Macular Edema (DME)

Pakistan
Aerpio Therapeutics

Completed

The TIME-2 Study: A Phase 2 Study of AKB-9778, a Novel Tie-2 Activator, in Patients With Diabetic Macular Edema (TIME-2)

Diabetic Macular Edema (DME)

United States
Alimera Sciences

Terminated

Observational Study to Assess the Effect of Iluvien® in DME Patients Insufficiently Responsive to Available Therapies (ILUMINATE)

Diabetic Macular Edema (DME)

Germany
Johns Hopkins University
SARcode Bioscience

Terminated

SAR 1118 in Human Subjects Undergoing Pars Plana Vitrectomy

Pars Plana Vitrectomy | Diabetic Macular Edema (DME)

United States
Future University in Egypt

Not yet recruiting

The Effect of Bulk Filling Flowable Composite on Caries Recurrence in Deep Marginal Elevation: a Randomized Clinical Trial

Dental Caries | DME | Dental | Deep Margin Elevation
Jemincare

Not yet recruiting

Study of JMKX003948 Ophthalmic Suspension in Healthy Participants

Age-Related Macular Degeneration (AMD) | Diabetic Macular Edema (DME)
Unity Biotechnology, Inc.

Completed

Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)

Diabetic Macular Edema (DME)

United States, Canada
AsclepiX Therapeutics, Inc.

Terminated

Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema (CONGO)

Diabetic Macular Edema (DME)

United States
Retina Consultants of Orange County
Regeneron Pharmaceuticals

Not yet recruiting

High Dose Aflibercept in Diabetic Macular Edema in Patients With Previous Vitrectomy

Diabetic Macular Edema (DME)

United States
ZeaVision, LLC
Sound Retina

Unknown

Prospective Study of Adjunctive Carotenoids Plus Anti-oxidants in Anti-VEGF Treated Diabetic Macular Edema (PROACTIVEDME)

Center-involved Diabetic Macular Edema (CI-DME)

United States
Bayer

Not yet recruiting

A Study to Learn More About the Use of Aflibercept in Routine Medical Practice in Japanese Participants With Neovascular Age-related Macular Degeneration and Diabetic Macular Edema

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD)

Japan
Regeneron Pharmaceuticals

Completed

Study to Evaluate an 8 mg Aflibercept (EYLEA®) Prefilled Syringe (PFS)

Diabetic Macular Edema (DME) | Neovascular Age-Related Macular Degeneration (nAMD)

United States
EyeBiotech Ltd.

Completed

A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD) (AMARONE)

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (NVAMD)

United States, Argentina, Puerto Rico, United Kingdom
University Hospital, Alexandroupolis

Recruiting

Impact of Intravitreal Faricimab on Renal Function in Diabetic Patients

Renal Function Disorder | Diabetic Macular Edema (DME) | Neovascular Age Related Macular Degeneration

Greece
Ankara Etlik City Hospital

Completed

The Relationship Between Serum Endocan and ADMA Levels and Penile Doppler Ultrasonography in Erectile Dysfunction

Evaluation of the Relationship Between Serum Biomarkers (Endocan and ADMA) and Penile Doppler Ultrasonography Findings of Patients With Severe Erectile Dysf

Turkey
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Italy, Spain, Netherlands, Switzerland, Canada, Japan, Denmark, Sweden, Korea, Republic of, France, Finland, Portugal, Australia, Saudi Arabia, United Arab Emirates, Norway, United Kingdom
National Eye Institute (NEI)

Completed

Treatment of Diabetic Macular Edema: Triamcinolone Injections Vs. Laser Photocoagulation

Diabetic Retinopathy | Diabetic Macular Edema | DME

United States
Bayer
Regeneron Pharmaceuticals

Completed

Evaluation of Physician Knowledge of Safety and Safe Use Information for Aflibercept in Canada

Diabetic Macular Edema (DME) | Age-related Macular Degeneration (AMD) | Central Retinal Vein Occlusion (CRVO)

Canada
Novartis Pharmaceuticals

Active, not recruiting

Observational Study to Evaluate Fluid Resolution and Effectiveness in Patients Receiving Beovu in Neovascular Age-related Macular Degeneration and Visual Impairment Due to Diabetic Macular Edema (BLUE SKY)

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD)

Germany
Novartis Pharmaceuticals

Completed

Observation of Treatment Patterns With Lucentis in Approved Indications (OCEAN)

Neovascular AMD, Visual Impairment Due to DME, Visual Impairment Due to Macular Oedema Secondary to Branch or Central RVO, Visual Impairment Due to CNV

Germany
Brigham and Women's Hospital

Completed

The Role of Mineralocorticoid Receptors in Vascular Function

Apparent Mineralocorticoid Excess (AME)

United States
Tanta University

Not yet recruiting

Effectiveness of Intravitreal Injection of Aflibercept 8 mg in Resistant Diabetic Macular Edema, Retinal Vein Occlusion and Myopic Choroidal Neovascularisation Patients

Diabetic Macular Edema (DME) | Myopic Choroidal Neovascularisation | Retinal Vein Occlusion (RVO)

Egypt
Regeneron Pharmaceuticals

Withdrawn

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
EyeBiotech Ltd.

Recruiting

A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration

Diabetic Macular Edema (DME) | BRVO - Branch Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration (NVAMD)

United States, Puerto Rico
Hywel Dda Health Board
University of Aberdeen

Recruiting

Investigating the Metabolic and Lipidomic Profiles That Are Associated With Varying Grades of Diabetic Maculopathy and Retinopathy in South Wales (IMLADRIS)

Diabetic Macular Edema (DME) | Diabetic Retinopathy (DR) | Diabetic Retinopathy Associated With Type 2 Diabetes Mellitus

United Kingdom
AbbVie
REGENXBIO Inc.

Recruiting

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) With and Without Center Involved-Diabetic Macular Edema (CI-DME) (ALTITUDE®)

Diabetic Retinopathy (DR) | Center-Involved Diabetic Macular Edema (CI-DME)

United States
Bristlecone Health, Inc.
University of Minnesota

Unknown

Photobiomodulation & Ketogenic Diet for Treatment of Mid-periphery Retinal Disorders for Alzheimer's Disease Prevention

Diabetic Macular Edema (DME) | Age-related Macular Degeneration (AMD) | Diabetic Retinopathy (DR) | Mid-peripheral Drusen Formation

United States

Clinical Trials on Avanfil ADME

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Costa Rica

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations