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Clinical Trials on Basal Cell Nevus Syndrome

Total 36 results

NCT04416516

Recruiting

Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor

Conditions: Basal Cell Carcinoma; Basal Cell Nevus Syndrome
NCT04308395

Enrolling by invitation

Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome)

Conditions: Basal Cell Nevus Syndrome
NCT04155190

Recruiting

An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

Conditions: Recurrent Basal Cell Carcinoma
NCT03767439

Withdrawn

Nivolumab With Vismodegib in Patients With Basal Cell Nevus Syndrome

Conditions: Basal Cell Nevus Syndrome
NCT03703310

Active, not recruiting

Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)

Conditions: Basal Cell Nevus Syndrome
NCT03483441

Recruiting

Vitamin D and Photodynamic Therapy for Treatment of BCC in BCNS

Conditions: Basal Cell Nevus Syndrome; Basal Cell Carcinoma
NCT03467789

Recruiting

Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma

Conditions: Basal Cell Carcinoma; Basal Cell Nevus Syndrome
NCT03208296

Suspended

Study of ASN-002 to Treat Basal Cell Carcinomas (BCCs) in Individuals With Basal Cell Nevus Syndrome (BCNS)

Conditions: Basal Cell Carcinoma in Basal Cell Nevus Syndrome
NCT03070691

Withdrawn

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Conditions: Basal Cell Carcinoma
NCT03050268

Recruiting

Familial Investigations of Childhood Cancer Predisposition

Conditions: Acute Leukemia; Adenomatous Polyposis; Adrenocortical Carcinoma; AML; BAP1 Tumor Predisposition Syndrome; Carney Complex; Choroid Plexus Carcinoma; Constitutional Mismatch Repair Deficiency Syndrome; Diamond-Blackfan Anemia; DICER1 Syndrome; Dyskeratosis Congenita; Emberger Syndrome; Familial Acute Myeloid Leukemia; Familial Adenomatous Polyposis; Fanconi Anemia; Familial Cancer; Familial Wilms Tumor; Familial Neuroblastoma; GIST; Hereditary Breast and Ovarian Cancer; Hereditary Paraganglioma-Pheochromocytoma Syndrome; Hodgkin Lymphoma; Juvenile Polyposis; Li-Fraumeni Syndrome; Lynch Syndrome; MDS; Melanoma Syndrome; Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2; Neuroblastoma; Neurofibromatosis Type 1; Neurofibromatosis Type II; Nevoid Basal Cell Carcinoma Syndrome; Non Hodgkin Lymphoma; Noonan Syndrome and Other Rasopathy; Overgrowth Syndromes; Pancreatic Cancer; Peutz-Jeghers Syndrome; Pheochromocytoma/Paraganglioma; PTEN Hamartoma Tumor Syndrome; Retinoblastoma; Rhabdoid Tumor Predisposition Syndrome; Rhabdomyosarcoma; Rothmund-Thomson Syndrome; Tuberous Sclerosis; Von Hippel-Lindau Disease
NCT02828111

Completed

Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell Carcinomas

Conditions: Basal Cell Carcinomas
NCT02762084

Completed

Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas in Gorlin Syndrome Patients

Conditions: Basal Cell Nevus Syndrome
NCT02639117

Completed

Photodynamic Therapy and Vismodegib for Multiple Basal Cell Carcinomas

Conditions: Basal Cell Carcinoma
NCT02550678

Completed

A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma

Conditions: Basal Cell Nevus Syndrome; Skin Neoplasm; Nodular Basal Cell Carcinoma of Skin
NCT02354261

Completed

Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS)

Conditions: Basal Cell Carcinoma in Basal Cell Nevus Syndrome
NCT02303041

Terminated

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Conditions: Carcinoma, Basal Cell; Recurrent Skin Cancer; Skin Neoplasms; Basal Cell Nevus Syndrome
NCT02157623

Completed

Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome

Conditions: Basal Cell Nevus Syndrome
NCT02100371

Completed

Study of BMS-833923 in Two Specific Patients With Basal Cell Nevus Syndrome

Conditions: Basal Cell Nevus Syndrome
NCT02017964

Active, not recruiting

Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma

Conditions: Desmoplastic/Nodular Medulloblastoma; Medulloblastoma; Medulloblastoma With Extensive Nodularity; Nevoid Basal Cell Carcinoma Syndrome; Untreated Childhood Medulloblastoma
NCT01893892

Completed

Levocarnitine in Treating Patients With Vismodegib-Associated Muscle Spasms

Conditions: Musculoskeletal Complications
NCT01815840

Completed

A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas

Conditions: Basal Cell Carcinoma
NCT01604252

Terminated

An Observational Study of Treatment Patterns and Effectiveness and Safety Outcomes in Advanced Basal Cell Carcinoma and Basal Cell Carcinoma Nevus Syndrome Patients(RegiSONIC)

Conditions: Basal Cell Carcinoma
NCT01556009

Completed

Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas

Conditions: Basal Cell Nevus Syndrome; Gorlin's Syndrome
NCT01463709

Completed

Development of a Nanosecond Pulsed Electric Field System to Treat Skin Cancer

Conditions: Basal Cell Carcinomas
NCT01350115

Completed

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Conditions: Basal Cell Carcinoma; Gorlin Syndrome; Nevoid Basal Cell Carcinoma Syndrome
NCT01014819

Completed

A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions

Conditions: Basal Cell Carcinoma
NCT00961896

Completed

A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients

Conditions: Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients
NCT00957229

Completed

To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)

Conditions: Basal Cell Nevus Syndrome; Gorlin Syndrome
NCT00783965

Completed

Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and Back

Conditions: Skin Carcinoma
NCT00555633

Completed

Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients

Conditions: Skin Cancer; Xeroderma Pigmentosum; Basal Cell Nevus Syndrome
NCT00489086

Completed

Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Face

Conditions: Neoplastic Syndrome
NCT00433485

Completed

Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants

Conditions: Neoplastic Syndrome; Non-melanomatous Skin Cancer
NCT00025012

Completed

Isotretinoin in Preventing Skin Cancer

Conditions: Melanoma (Skin); Non-melanomatous Skin Cancer
NCT00023621

Completed

Celecoxib in Preventing Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome

Conditions: Non-melanomatous Skin Cancer
NCT00049959

Terminated

Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.

Conditions: Basal Cell Carcinoma; Nevoid Basal Cell Carcinoma Syndrome; Gorlin Syndrome
NCT00005660

Completed

The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive Diseases

Conditions: Basal Cell Carcinoma; Keratosis Palmaris et Plantaris; Psoriasis

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Clinical Trials on Basal Cell Nevus Syndrome