Clinical Trials on Blast or Combat Exposure

Total 109 results

Stanford University

Active, not recruiting

Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure

Head Injury Trauma | Blast or Combat Exposure

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Acute Myeloid Leukemia | Previously Treated Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | Myeloproliferative Neoplasm | Myeloid Sarcoma | Blasts 10 Percent or More of Bone Marrow Nucleated Cells

United States
National Cancer Institute (NCI)

Terminated

Relationship of Genetic Differences to the Development of Chromosome Abnormalities

Radiation Exposure

Russian Federation
West China Hospital
Xiamen Health Commission; Xiamen Health and Medical Big Data Center

Completed

A Population-based Study of Drug Exposures and Adverse Pregnancy Outcomes in China (DEEP)

Pregnancy | Congenital Malformation | Drug Exposure

China
William Shomali
Incyte Corporation

Recruiting

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Eosinophilia | Hypereosinophilic Syndrome | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | Splenomegaly | Hepatomegaly | Chronic Eosinophilic Leukemia, Not Otherwise Specified | JAK2 Gene Mutation | BCR-JAK2 Fusion Protein Expression | Blasts 20 Percent or Less of Peripheral Blood White... and other conditions

United States
LEO Pharma
Bayer

Completed

A Study to Learn More About the Relationship Between the Development of a Gap in the Upper Lip (Cleft Lip) or in the Roof of the Mouth (Cleft Palate) in Newborns and the Use of Glucocorticoids by the Mother During Pregnancy: a Meta-analysis

Relationship Between the Exposure of Glucocorticoids During Pregnancy and Orofacial Cleft Development

Germany
Fangbiao Tao

Completed

The China-Anhui Birth Cohort Study (C-ABCS)

Birth Defects | Environmental Exposures | Other Pregnancy With Abortive Outcome | Children Development
Northwell Health

Terminated

1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain

High Risk MC4R Genotype | Low Risk MC4R Genotype | One Week or Less Antipsychotic Lifetime Exposure

United States
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies

Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome RAEB-I or RAEB-II | Refractory CML Myeloid Blast Crisis

United States
Anhui Medical University
Ma'anshan Maternal and Child Health Care Hospital

Active, not recruiting

The Ma'Anshan Birth Cohort (MABC)

Birth Defects | Child Development | Pregnancy Outcome | Environmental Exposure | Maternal and Child Health | Health Problems in Pregnancy

China
University Hospital, Lille

Active, not recruiting

Effects of Prenatal Alcohol Exposure on Emotional and Cognitive Abilities in Adults (ALTEMO)

Prenatal Alcohol Exposure

France
Yorkshire Ambulance Service NHS Trust
National Institute for Health Research, United Kingdom

Not yet recruiting

The Effects of Dog Therapy on Ambulance Staff Burnout Scores. (Pawamedics)

Burn Out | EMS Exposures or Injuries of EMS Personnel
Hospital Clínico Universitario de Valladolid

Completed

Genomic Instability in Vascular Surgeons (IRADIENT)

Radiation Exposure | Cytogenetic Abnormality

Spain
Boston Children's Hospital
National Institute of Neurosciences and Hospital, Dhaka

Recruiting

Understanding Effects of Folic Acid on the Methylosome and Transcriptome of Women With Spina Bifida Affected Pregnancies

Environmental Exposure | Pregnancy; Spina Bifida, Fetal

Bangladesh
Roswell Park Cancer Institute
Celgene

Withdrawn

Enasidenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia With an IDH2 Gene Mutation

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | IDH2 Gene Mutation | Blasts Under 5 Percent of Peripheral Blood White Cells | Bone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment Level

United States
University of Washington
National Cancer Institute (NCI)

Completed

Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts-2 | Myeloid Neoplasm | Chronic Myelomonocytic Leukemia-2 | Blasts 10 Percent or More of Bone Marrow Nucleated... and other conditions

United States
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Roswell Park Cancer Institute
Pfizer

Withdrawn

Inotuzumab Ozogamicin and Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Blasts 5 Percent or More of Bone Marrow Nucleated Cells | CD22 Positive | Allogeneic Hematopoietic Stem Cell Transplantation Recipient | Blasts 5 Percent or More of Peripheral Blood White Cells | Lymphoblasts... and other conditions

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); Eli Lilly and Company; Kanisa Pharmaceuticals

Completed

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

Myelodysplastic Syndromes | Leukemia

United States, Israel
National Cancer Institute (NCI)

Completed

CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) and other conditions

United States
Stichting Hemato-Oncologie voor Volwassenen Nederland

Completed

Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia

United Kingdom
Beth Israel Deaconess Medical Center
Amgen

Completed

Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders (MINI HEME)

AML | MDS | CLL | ALL | CML Chronic Phase, Accelerated Phase, or Blast Crisis | RELAPSED NON-HODGKIN'S OR HODGKIN'S LYMPHOMA | APLASTIC ANEMIA | MULTIPLE MYELOMA | MYELOPROLIFERATIVE DISORDER (P Vera, CMML, ET)
University of the French West Indies and French...
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Sickle Cell Trait and Exercise, Effect of Hot Environment (TDex)

Environmental Exposure | Sickle Cell Trait | Adverse Effect

Guadeloupe
City of Hope Medical Center

Terminated

Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Myeloid Cancer

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Eisai Inc.

Completed

A Study of Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Participants Who Have Experienced CINV(Chemotherapy-Induced Nausea and Vomiting) During the Previous Cycle of Low Emetogenic Chemotherapy (LEC)

Patients With Confirmed Malignant Disease to Receive Low Emetogenic Chemotherapy (LEC) or Who Experienced at Least Nausea and Vomiting During Last Cycle of LEC

United States
University of British Columbia
Canadian Institutes of Health Research (CIHR); AllerGen NCE Inc.

Recruiting

Diesel Exhaust Induces Glucocorticoid Resistance (DIGR)

Exposure to Pollution | Glucocorticoid Resistance

Canada
National Cancer Institute (NCI)

Completed

Rebeccamycin Analog in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) and other conditions

United States
University of Washington
National Cancer Institute (NCI)

Completed

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

Chronic Myelomonocytic Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22... and other conditions

United States
West China Hospital
Xiamen Health Commission; Xiamen Health and Medical Big Data Center

Active, not recruiting

Miscarriage Preventing Herbal Medicines and the Risk of Birth Defects: a Population-based Cohort Study

Pregnancy | Birth Defects | Drug Exposures

China
Bezmialem Vakif University
Maternal Fetal Medicine and Perinatology Society of Turkey

Active, not recruiting

Effects of Maternal Smoking on Fetal Liver Circulation

Ultrasound | Smoking, Cigarette | Liver | Maternal Exposure | Fetal; Circulation

Turkey
FibroGen
AstraZeneca; Astellas Pharma Inc

Terminated

Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden

Primary MDS (Very Low, Low or Intermediate IPSS-R With <5% Blasts)

United States, Australia, Belgium, Germany, Israel, Italy, Korea, Republic of, Russian Federation, Spain, United Kingdom, France, Turkey, Canada, Denmark, India, Poland
University of Colorado, Denver
National Institute on Drug Abuse (NIDA)

Completed

The Influence of in Utero Cannabis Exposure on Neonatal Brain Morphology and Structural Connectivity

Drug Use | Neurodevelopmental Abnormality | Cannabis Use Disorder | PREG1 | Fetal Exposure During Pregnancy

United States
Rennes University Hospital

Completed

Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages (MacFibOsis)

History of Exposure to Silica or Asbestosis | Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases

France
Heartland Health Research Alliance
Indiana University School of Medicine

Recruiting

The Heartland Study

Pregnancy Complications | Pregnancy Related | Miscarriage | Gestational Age and Weight Conditions | Spontaneous Abortion | Birth Defect | Exposure to Herbicides

United States
Sumithira Vasu
Kiadis Pharma

Recruiting

Trial Testing Safety of IL-21 NK Cells for Induction of R/R AML

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Blasts 10 Percent or More of Bone Marrow Nucleated Cells | Allogeneic Stem Cell Transplant Recipient

United States
Boston Children's Hospital
National Institute of Environmental Health Sciences (NIEHS)

Recruiting

Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD (AeroBPD)

Bronchopulmonary Dysplasia | Environmental Exposure | Chronic Lung Disease of Newborn

United States
Nantes University Hospital

Active, not recruiting

Neuropsychological Development and Executive Functioning of Children Born to HIV- Infected Mothers ( NEUROPSY-HEU ) (NEUROPSY-HEU)

HIV Infections | Executive Dysfunction | Neurophysiologic Abnormality | Exposure During Pregnancy

France
Centre Hospitalier Intercommunal Creteil

Not yet recruiting

Real World Environmental Exposure Study With Healthy and Cystic Fibrosis Subjects (ExpoCF)

Environmental Exposure | Cystic Fibrosis, Pulmonary | Exhaled Breath Condansate
Centre Hospitalier St Anne

Recruiting

EXPRE-SON-REA : Expressive Own Names in Neurophysiologic Assessment of Comatose Patients (EXPRESONREA)

Comatose | Neurophysiologic Abnormality

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Laboratory-Treated (Central Memory/Naive) CD8+ T Cells in Treating Patients With Newly Diagnosed or Relapsed Acute Myeloid Leukemia

Acute Myeloid Leukemia | EBV-Positive Neoplastic Cells Present | HLA-A*0201 Positive Cells Present | Blasts Under 5 Percent of Bone Marrow Nucleated Cells | Elevated WT1

United States
Astana Medical University

Completed

Influence of Vibroacoustic Therapy Modes on the Course of Coronavirus Infection

COVID-19 | Acute Respiratory Failure | Vibration; Exposure

Kazakhstan
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
University of California, San Francisco
Universidad del Valle, Guatemala

Completed

NACER II: Reducing Prenatal Exposures to Household Air Pollution in Rural Guatemala Through a Gas Stove/Behavior Intervention to Improve Neonatal Health

Premature Birth | Fetal Growth Retardation | Infant, Small for Gestational Age | Infections, Respiratory | Exposure to Environmental Pollution, Non-occupational

Guatemala
Andrea Rossetti, MD

Completed

Continuous EEG Randomized Trial in Adults (CERTA)

Coma | Outcome, Fatal | EEG With Abnormally Slow Frequencies | EEG With Periodic Abnormalities

Switzerland
National Cancer Institute (NCI)

Completed

SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
San Diego State University

Completed

Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders

Fetal Alcohol Spectrum Disorders | Prenatal Alcohol Exposure | Fetal Alcohol Syndrome | Partial Fetal Alcohol Syndrome | Alcohol-related Neurodevelopmental Disorder

United States
University of Minnesota
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Prenatal Alcohol Exposure | Fetal Alcohol Syndrome | Partial Fetal Alcohol Syndrome | Alcohol Related Neurodevelopmental Disorder

United States
Vanderbilt University Medical Center
University of California, Los Angeles; University of California, San Francisco and other collaborators

Terminated

Goal of Open Lung Ventilation in Donors (GOLD)

Brain Death | Organ Donation | Organ Transplant Failure or Rejection

United States

Clinical Trials on Blast or Combat Exposure

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bosnia & Herzegovina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations