Clinical Trials on Brain Glioma

Total 32085 results

Cheng-Chia (Fred) Wu
Focused Ultrasound Foundation

Active, not recruiting

Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Diffuse Pontine and Thalamic Gliomas

United States
Medical College of Wisconsin

Not yet recruiting

A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas

Glioma | Brain Cancer | Brain Tumor | Glioma Intracranial | Gliomas Benign | Motor Cortex; Lesion
Luca Szalontay
Midatech Pharma US Inc.

Completed

CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Diffuse Pontine and Thalamic Gliomas

United States
Dushu Lake Hospital Affiliated to Soochow University

Recruiting

Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection

Brain Gliomas

China
Memorial Sloan Kettering Cancer Center
Columbia University; University of Wisconsin, Madison; Keryx Biopharmaceuticals; Keryx / AOI Pharmaceuticals, Inc... and other collaborators

Completed

Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas

Cancer | Brain Cancer | Malignant Gliomas | CNS

United States
National Cancer Institute (NCI)

Recruiting

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Glioma | High Grade Glioma | Malignant Glioma | Gliomas | Low Grade Glioma

United States
Martin-Luther-Universität Halle-Wittenberg
Merck KGaA, Darmstadt, Germany

Terminated

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents (HGG-CilMetro)

Gliomas

Germany
Baylor College of Medicine
M.D. Anderson Cancer Center; University of Oklahoma; The University of Texas... and other collaborators

Completed

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Gliomatosis Cerebri | Brainstem Glioma | Malignant Gliomas | Glial Cell Tumors

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.; Weill Medical College of Cornell University

Completed

Bevacizumab in the Radiation Treatment of Recurrent Malignant Glioma

Brain Cancer | Primary Brain Tumor | Recurrent Malignant Gliomas

United States
Memorial Sloan Kettering Cancer Center
Columbia University; Genentech, Inc.; University of California, San Francisco

Completed

Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma

Glioblastoma | Brain Cancer | Anaplastic Astrocytoma (AA) | Anaplastic Oligodendroglioma (AO) | MALIGNANT GLIOMA | Anaplastic Oligo-astrocytoma (AOA) | Anaplastic Mixed Gliomas | Malignant Glioma NOS

United States
University of Texas Southwestern Medical Center
Cancer Prevention Research Institute of Texas

Completed

Clinical Development of MR Spectroscopy and Imaging in Brain Cancers

Malignant Gliomas | Astrocytomas | Oligodendrogliomas

United States
Sanofi

Completed

A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas

Glioblastoma Multiforme | Malignant Gliomas | Mixed Gliomas

United States
Sklifosovsky Institute of Emergency Care

Recruiting

General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas (GAMMA)

Glioma, Malignant | Gliomas Benign | Metastases to Brain

Russian Federation
Children's Hospital Medical Center, Cincinnati
Genentech, Inc.

Completed

A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas

Diffuse Intrinsic Pontine Glioma | Newly Diagnosed High-Grade Gliomas

United States
Children's Hospital Medical Center, Cincinnati
Novartis

Completed

A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

Glioblastoma | Malignant Glioma of Brain | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brainstem Glioma | Bithalamic High Grade Glioma

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Patients With Brain Stem Glioma

Brain Stem Gliomas

United States
National Cancer Institute (NCI)

Terminated

Sunitinib to Treat Recurrent Brain Cancer

Glioblastoma Multiforme | Malignant Gliomas | Anaplastic Gliomas

United States
Tilburg University

Completed

Effects of Exercise on Cognitive Function in Glioma Patients

Low Grade Glioma of Brain | Anaplastic Glioma of Brain

Netherlands
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium and Radiation Therapy in Treating Young Patients With Pontine Glioma

Untreated Childhood Brain Stem Glioma

United States
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Untreated Childhood Brain Stem Glioma

United States
Nationwide Children's Hospital
Novartis

Not yet recruiting

Study of Ribociclib and Everolimus in HGG and DIPG

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Nationwide Children's Hospital

Not yet recruiting

Targeted Pediatric High-Grade Glioma Therapy

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Beijing Tiantan Hospital
ZhongSheng BioTech Inc.

Recruiting

Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas

WHO Grade III Gliomas | WHO Grade IV Gliomas

China
Children's Hospital of Philadelphia
Blue Earth Diagnostics; Dragon Master Foundation

Not yet recruiting

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

Glioma | Low-grade Glioma | Glioma, Malignant | Low Grade Glioma of Brain | Glioma Intracranial

United States
National Cancer Institute (NCI)

Completed

Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma

Untreated Childhood Brain Stem Glioma

United States
Universitaire Ziekenhuizen KU Leuven

Unknown

Multimodal MR Imaging in Patients With Glioblastoma Treated With Dendritic Cell Therapy

Malignant Gliomas

Belgium
Emory University

Completed

Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Recurrent Brain Tumor | Mixed Gliomas
YM BioSciences

Completed

Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma

Recurrent Diffuse Pontine Gliomas

United States, Canada, Israel
National Cancer Institute (NCI)

Completed

Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors

Brain Tumors | High Grade Gliomas

United States
Meyer Children's Hospital

Terminated

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Anaplastic Astrocytoma | DIPG | Gliomatosis Cerebri | Glioblastoma (GBM) | Brainstem Glioma, Pediatric | Diffuse Spinal Glioma | Bilateral Thalamic Glioma | Midline Diffuse Glioma

Italy
Tata Memorial Hospital

Completed

Fluorescence and Glioma Heterogeneity (ALAglioma)

Malignant Gliomas

India
Oliver Jonas, PhD

Recruiting

Implantable Microdevice In Primary Brain Tumors

Glioblastoma | Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Astrocytoma of Brain | Grade III Glioma | Grade IV Glioma | Grade II Glioma | Oligodendroglioma of Brain

United States
Nationwide Children's Hospital
Pfizer

Not yet recruiting

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | WHO Grade III Glioma | WHO Grade IV Glioma | Infant Type Hemispheric Glioma | Diffuse Midline Glioma, H3K27-altered

United States, Australia, Canada, Germany, Netherlands
Crystal Mackall, MD
National Institutes of Health (NIH); California Institute for Regenerative... and other collaborators

Recruiting

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Glioma of Spinal Cord | Glioma of Brainstem

United States
Bambino Gesù Hospital and Research Institute

Recruiting

GD2-CAR T Cells for Pediatric Brain Tumours

High Grade Glioma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Embryonal Tumor | Brain Tumor Adult | Brain Tumor, Pediatric

Italy
University of Florida
Accelerate Brain Cancer Cure; Lyla Nsouli Foundation

Active, not recruiting

Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) (BRAVO)

Brain Stem Glioma | Diffuse Intrinsic Pontine Glioma (DIPG)

United States
Neurological Associates of West Los Angeles

Enrolling by invitation

The Use of Focused Ultrasound and DCE K-trans Imaging to Evaluate Permeability of the Blood-Brain Barrier

Low Grade Glioma of Brain

United States
National Cancer Institute (NCI)

Completed

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Untreated Childhood Brain Stem Glioma | Giant Cell Glioblastoma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliosarcoma | Brain Stem Glioma | Untreated... and other conditions

United States
University of California, San Francisco
National Institute of Neurological Disorders and Stroke (NINDS); The Chad-Tough... and other collaborators

Recruiting

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent WHO Grade III Glioma | WHO Grade III Glioma

United States, Israel, Australia, Netherlands, Switzerland, New Zealand
Children's Hospital Medical Center, Cincinnati
Novartis

Terminated

A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy

High Grade Glioma | Diffuse Intrinsic Pontine Glioma | Bithalamic High Grade Glioma

United States
Rigshospitalet, Denmark
Karolinska University Hospital; Aarhus University Hospital; Sahlgrenska University... and other collaborators

Not yet recruiting

RE-irradiation of Diffuse MIdline Glioma paTients (REMIT)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Diffuse Glioma | Pontine Tumors | Brain Tumor, Pediatric | Thalamic Tumor
Constantinos Hadjipanayis
Massachusetts General Hospital

Completed

5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor

Malignant Gliomas

United States
Children's Hospital Medical Center, Cincinnati
The DIPG Collaborative

Recruiting

International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Diffuse Midline Glioma

United States
SonoClear AS

Recruiting

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Glioblastoma | High Grade Glioma | Low-grade Glioma | Brain Tumour

Germany, Slovakia, Italy
Dana-Farber Cancer Institute
Celgene; Secura Bio, Inc.

Terminated

Phase I Study of Marizomib + Panobinostat for Children With DIPG (DIPG)

Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Diffuse Glioma | Pediatric Brainstem Glioma | Pediatric Brainstem Gliosarcoma, Recurrent

United States
Weill Medical College of Cornell University

Terminated

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Glioblastoma Multiforme | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brain Stem Glioma | Pilomyxoid Astrocytoma | Glioma of Brainstem | Fibrillary Astrocytoma of Brain | Mixed Oligodendroglioma-Astrocytoma

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Brigham... and other collaborators

Completed

Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiforme

Glioblastoma | Gliosarcoma | Malignant Gliomas

United States
Hadassah Medical Organization

Completed

Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children

Pediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma

Israel
Colombian Foundation for Epilepsy and Neurological...

Unknown

Efficacy of Tranexamic Acid in Brain Tumor Resections (COLFIRE)

Neoplasms | Brain Tumors | Gliomas | Astrocytomas | Meningiomas

Colombia
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial

Meningioma | Low Grade Glioma | Malignant Brain Neoplasm | Malignant Brain Glioma

United States

Clinical Trials on Brain Glioma

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