Clinical Trials on Brainstem Glioma

Total 2909 results

Helsinki University Central Hospital
Turku University Hospital; Oulu University Hospital; Kuopio University Hospital; Tampere University Hospital

Completed

ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors

Brainstem Glioma

Finland
Eurofarma Laboratorios S.A.
Centro de Immunologia Molecular, Cuba

Completed

Nimotuzumab and Radiotherapy in Pediatric Patients With Glioma (POLARIS)

Diffuse Intrinsic Brainstem Gliomas

Brazil, Cuba
Beijing Tiantan Hospital
Duke University

Unknown

Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1) (InSituVac1)

Glioblastoma | High Grade Glioma | Glioma, Malignant | Glioma of Brainstem

China
Hoffmann-La Roche
Pediatric Brain Tumor Consortium

Completed

A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas

Brainstem Glioma

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

First-line Chemotherapy With Temozolomide Alone for Non-enhancing Adult Brainstem Gliomas, With a Diffuse Subtype and Showing Clinical and/or Radiological Infiltrative Pattern of Progression (TEMOTRAD01)

Adult Brainstem Glioma

France
Dana-Farber Cancer Institute
Celgene; Secura Bio, Inc.

Terminated

Phase I Study of Marizomib + Panobinostat for Children With DIPG (DIPG)

Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Diffuse Glioma | Pediatric Brainstem Glioma | Pediatric Brainstem Gliosarcoma, Recurrent

United States
National Cancer Institute (NCI)

Withdrawn

A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With Gliomas

Astrocytoma | Glioblastoma Multiforme | Ependymoma | PNET | Brainstem Glioma
Children's Hospital Medical Center, Cincinnati

Completed

Comparative Effects of Two Anesthetic Techniques on Auditory Brain Response in Children

Auditory Brainstem Response

United States
Baylor College of Medicine
M.D. Anderson Cancer Center; University of Oklahoma; The University of Texas... and other collaborators

Completed

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Gliomatosis Cerebri | Brainstem Glioma | Malignant Gliomas | Glial Cell Tumors

United States
Cantonal Hospital of St. Gallen

Recruiting

Data Collection and Analysis in Brainstem Surgeries

Surgery | Brainstem Lesion | Intraoperative Neurophysiologic Monitoring

Switzerland
Fondation Lenval

Completed

Intranasal Dexmedetomidine for Sedated Hearing Testing

Auditory Brainstem Response

France
National Cancer Institute (NCI)

Completed

AZD8055 for Adults With Recurrent Gliomas

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Brainstem Glioma

United States
Children's Hospital Medical Center, Cincinnati
Novartis

Completed

A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

Glioblastoma | Malignant Glioma of Brain | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brainstem Glioma | Bithalamic High Grade Glioma

United States
Meyer Children's Hospital

Terminated

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Anaplastic Astrocytoma | DIPG | Gliomatosis Cerebri | Glioblastoma (GBM) | Brainstem Glioma, Pediatric | Diffuse Spinal Glioma | Bilateral Thalamic Glioma | Midline Diffuse Glioma

Italy
Crystal Mackall, MD
National Institutes of Health (NIH); California Institute for Regenerative... and other collaborators

Recruiting

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Glioma of Spinal Cord | Glioma of Brainstem

United States
Washington University School of Medicine

Withdrawn

Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas

Astrocytoma | Ependymoma | Oligodendroglioma | Brainstem Glioma | Mixed Glioma | Optic Nerve Glioma
Pontificia Universidade Catolica de Sao Paulo

Completed

Chloral Hydrate to Perform Auditory Brainstem Response (ABR)

Auditory Brainstem Response in Children | Sedation With Chloral Hydrate

Brazil
Clinica Universidad de Navarra, Universidad de...
DNAtrix, Inc.; Alcyone Lifesciences, Inc.

Completed

Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas

Neoadjuvant Therapy | Brainstem Glioma

Spain
Children's National Research Institute

Recruiting

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Diffuse Intrinsic Pontine Glioma | Brainstem Glioma

United States
Brigham and Women's Hospital
National Cancer Institute (NCI); Dana-Farber Cancer Institute; University of...

Recruiting

MCT for the Harvard/UCSF ROBIN Center

Neuroblastoma | Glioma, Childhood Brainstem

United States
Weill Medical College of Cornell University

Terminated

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Glioblastoma Multiforme | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brain Stem Glioma | Pilomyxoid Astrocytoma | Glioma of Brainstem | Fibrillary Astrocytoma of Brain | Mixed Oligodendroglioma-Astrocytoma

United States
National Cancer Institute (NCI)

Recruiting

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Glioma | High Grade Glioma | Malignant Glioma | Gliomas | Low Grade Glioma

United States
Sanofi

Completed

A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas

Glioblastoma Multiforme | Malignant Gliomas | Mixed Gliomas

United States
University of Miami

Recruiting

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

Glioblastoma Multiforme | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | DIPG Brain Tumor | H3 K27M | Fibrillary Astrocytomas | Diffuse Intrinsic Brainstem Glioma

United States
Julie Krystal
Janssen Pharmaceuticals

Recruiting

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Pleomorphic Xanthoastrocytoma | Pilocytic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Low-grade Glioma | DIPG | Brainstem Glioma | Optic Nerve Glioma | Pilomyxoid Astrocytoma | Glioma, Astrocytic

United States
Second Affiliated Hospital, School of Medicine,...

Active, not recruiting

Stereotactic Aspiration for Primary Brainstem Hemorrhage Based on 'Zhe-er Classification'

Primary Brainstem Hemorrhage

China
National Cancer Institute (NCI)

Terminated

Sunitinib to Treat Recurrent Brain Cancer

Glioblastoma Multiforme | Malignant Gliomas | Anaplastic Gliomas

United States
Beijing Tiantan Hospital
ZhongSheng BioTech Inc.

Recruiting

Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas

WHO Grade III Gliomas | WHO Grade IV Gliomas

China
Hospital Infantil de Mexico Federico Gomez

Completed

Application of Palliative Treatment in Children With Brain Stem Glioma and Recurrent High-grade Tumors in the Central Nervous System With the Nanomaterial NPt-Ca

Brain Tumor, Pediatric, Brainstem Glioma | Brain Tumor, Pediatric, Recurrent

Mexico
Universitaire Ziekenhuizen KU Leuven

Unknown

Multimodal MR Imaging in Patients With Glioblastoma Treated With Dendritic Cell Therapy

Malignant Gliomas

Belgium
Tata Memorial Hospital

Completed

Fluorescence and Glioma Heterogeneity (ALAglioma)

Malignant Gliomas

India
University Hospital Tuebingen

Completed

Vegetative Monitoring During Brainstem-associated Surgery

Brain Tumor, Recurrent | Vestibular Schwannoma | Brainstem Glioma | Brainstem Neoplasm

Germany
CHU de Reims

Completed

Use of BRASS in Sedated Critically-ill Patients as a Predictable Mortality Factor (BRASS-ICU)

Brainstem Response

France
Dana-Farber Cancer Institute
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Brigham... and other collaborators

Completed

Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiforme

Glioblastoma | Gliosarcoma | Malignant Gliomas

United States
Constantinos Hadjipanayis
Massachusetts General Hospital

Completed

5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor

Malignant Gliomas

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Patients With Recurrent or Refractory Mixed Gliomas

Mixed Gliomas

United States
University of Colorado, Denver
AstraZeneca

Completed

Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant Gliomas (IRUSZACT0073)

Malignant Gliomas

United States
Peking Union Medical College Hospital
Beijing Tiantan Hospital; Tianjin Medical University General Hospital

Unknown

Efficacy and Safety of TMZ Plus CDDP in the Patients With Recurrent Malignant Gliomas

Malignant Gliomas

China
London Health Sciences Centre
University of Western Ontario, Canada; London Regional Cancer Program, Canada

Terminated

Imaging Study of Glioblastomas Treated With Avastin

Malignant Gliomas

Canada
Rigshospitalet, Denmark
Odense University Hospital; Aalborg University Hospital

Completed

Cetuximab, Bevacizumab and Irinotecan for Patients With Malignant Glioblastomas

Malignant Gliomas

Denmark
Eli Lilly and Company
Children's Oncology Group

Completed

A Study of Pemetrexed in Children With Recurrent Cancer

Osteosarcoma | Ependymoma | Medulloblastoma | Rhabdomyosarcoma | Sarcoma, Ewing's | Neuroblastoma (Measurable Disease) | Neuroblastoma (Metaiodobenzylguanidine | Positive Evaluable) | Non-brainstem High-grade Glioma

United States
National Cancer Institute (NCI)

Completed

ZD6474 to Treat Advanced Brain Cancer in Patients

Recurrent High-Grade Gliomas | Malignant Gliomas | Progressive Low-Grade Gliomas

United States
M.D. Anderson Cancer Center
Celgene

Terminated

Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase I

Malignant Gliomas

United States
Neurological Surgery, P.C.

Terminated

Study of LBH589 (Panobinostat) to Treat Malignant Brain Tumors

Recurrent Malignant Gliomas

United States
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas

Malignant Gliomas | Astrocytomas | Oligodendrogliomas

United States
University of Alberta
Capital Health, Canada

Completed

The Safety and Efficacy of DCA for the Treatment of Brain Cancer

Malignant Gliomas, Glioblastoma Multiforme

Canada
Tocagen Inc.

Terminated

A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511

Astrocytoma | Glioblastoma Multiforme | Gliomas, Malignant

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium

Terminated

Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
M.D. Anderson Cancer Center
BioMed Valley Discoveries, Inc

Recruiting

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Low-Grade Gliomas in Adults

Gliomas

United States

Clinical Trials on Brainstem Glioma

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