Clinical Trials on Cancer, Rectum

Total 52999 results

Wuhan Union Hospital, China

Recruiting

Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer

Rectal Cancer | Cancer of Rectum | Cancer of the Rectum | Rectum Cancer | Rectum Neoplasms | Neoplasms, Rectal | Rectal Tumors

China
Washington University School of Medicine

Completed

Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum (NORMAL-R)

Rectal Cancer | Cancer of Rectum | Cancer of the Rectum | Neoplasm, Rectum | Rectum Cancer | Rectum Neoplasms | Adenocarcinoma of the Rectum

United States
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Adenocarcinoma of the Rectum

United States
University of Utah

Not yet recruiting

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer (FACE)

Metastatic Colon Cancer | Metastatic Rectum Cancer

United States
Vejle Hospital
Aarhus University Hospital

Terminated

Predictive Value of 18F-FAZA in Rectum Cancer (FAZA)

Locally Advanced Rectum Cancer

Denmark
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Rectal Adenocarcinoma | Recurrent Rectal Cancer

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer

United States
Centre Hospitalier Universitaire, Amiens

Completed

Informativeness to Digital Rectal Examination (RIFIONA)

Hernia | Diverticulitis | Colon Cancer | Rectal Bleeding | Upper Rectum Cancer

France
Mater Misericordiae University Hospital
Penn State University; Krankenhaus der Barmherzigen Bruder Graz; Institut de... and other collaborators

Not yet recruiting

CLASSICA: Validating AI in Classifying Cancer in Real-Time Surgery Study 1

Rectal Cancer | Rectum Neoplasm | Rectum Polyp

Ireland
National Cancer Institute (NCI)

Completed

Oxaliplatin, Fluorouracil, and External-Beam Radiation Therapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum

Adenocarcinoma of the Rectum | Stage II Rectal Cancer | Stage III Rectal Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer

Adenocarcinoma of the Rectum | Stage II Rectal Cancer | Stage III Rectal Cancer

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Terminated

Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal Cancer

Adenocarcinoma of the Rectum | Stage II Rectal Cancer | Stage III Rectal Cancer

United States, Canada, Puerto Rico, Peru
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer (STELLAR)

Cancer, Rectum

China
Institut Cancerologie de l'Ouest
Fondation ARC

Active, not recruiting

64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum)

Rectal Cancer

France
Maastricht Radiation Oncology

Completed

Rectal Study: Value of Repeated FDG-PET-CT Scans in Rectal Cancer

Rectum Cancer

Netherlands
University Hospital, Geneva

Recruiting

Neo-adjuvant Pembrolizumab and Radiotherapy in Localised MSS Rectal Cancer (PEMREC)

Rectal Cancer | Rectum Cancer

Switzerland
San Carlo di Nancy Hospital

Recruiting

Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial (LOTHVEIN)

Colorectal Cancer | Anastomotic Leak | Colon Cancer | Colon Neoplasm | Rectum Cancer | Rectum Neoplasm | Anastomotic Leak Rectum | Anastomotic Leak Large Intestine

Italy
AC Camargo Cancer Center

Unknown

Study of Blood Components as Probable Prognostic and Predictive Markers of Response to Treatment in Advanced Colon and Rectal Cancers (BMACR)

Colon Cancer Stage IIb | Rectum Cancer, Adenocarcinoma | Colon Cancer Stage IIIa | Colon Cancer Stage IIIc | Colon Cancer Stage IIIb

Brazil
SCRI Development Innovations, LLC
Genentech, Inc.

Completed

5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer

Colorectal Cancer | Rectal Cancer | Cancer of the Rectum

United States
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Preoperative Radiotherapy And ASTX660 in Rectum Cancer (PRAAR1)

Locally-advanced Rectal Cancer

France
Washington University School of Medicine

Terminated

PET/MR for Rectal Cancer Treatment Monitoring and Surveillance

Rectal Cancer | Cancer of the Rectum

United States
Peking University Third Hospital

Completed

The Physical Dosimetry Study and Preliminary Clinical Results of 3D-printing Non Co-planar Template Assisted With CT-guidance for Iodine-125 Seed Brachytherapy in Pelvic Recurrent Rectum Carcinoma After Surgery and External Beam Radiotherapy

Rectum Cancer, Recurrent | Brachytherapy, Radioisotope
Siemens Molecular Imaging

Completed

Efficacy Study of [F-18]RGD-K5 Positron Emission Tomography (PET) as a Tool to Monitor Response to an Anti-angiogenic Drug (K5-101)

Non-squamous Non-small Cell Lung Cancer | Metastatic Breast Cancer | Metastatic Colon/Rectum Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Effectiveness and Implementation of mPATH-CRC

Cancer | Colorectal Cancer | Colon Cancer | Rectum Cancer

United States
Federation Francophone de Cancerologie Digestive

Completed

First Line Treatment by FOLFIRINOX for Patients With a Rectum Cancer With Synchronous Non Resectable Metastasis

Adenocarcinoma of Rectum

France
Kantonsspital Winterthur KSW

Recruiting

Long-term Cohort Study of Mesorectal Excision for Rectal Cancer (TME-KSW)

Cancer | Rectum

Switzerland
Fox Chase Cancer Center
National Cancer Institute (NCI)

Terminated

Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Umraniye Education and Research Hospital

Completed

Evaluating Factors Affecting Survival in Colon and Rectum Cancer

Colon Cancer | Rectum Cancer
University of California, San Francisco

Completed

Self-monitoring and Reminder Texts to Increase Physical Activity After Cancer: a Pilot Randomized Controlled Trial (Smart Pace)

Colon Cancer | Rectum Cancer

United States
M.D. Anderson Cancer Center
Bayer; Xencor, Inc.

Withdrawn

Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME)

Colorectal Cancer | Colon Cancer | Rectum Cancer

United States
National Cancer Institute (NCI)

Terminated

Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma...

United States
Hospital San Carlos, Madrid

Completed

"Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study".

Rectal Cancer Stage II | Rectal Cancer Stage III | Rectal Cancer, Adenocarcinoma | Distant Metastasis | Local Recurrence of Malignant Tumor of Rectum

Spain
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Southwest Oncology Group

Completed

Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
National Cancer Institute (NCI)

Completed

A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
University Hospital Ostrava

Recruiting

PREHAB - Improving Condition Before Surgery

Cancer, Rectum | Cancer, Digestive System

Czechia
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery

Mucinous Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer

United States
Blokhin's Russian Cancer Research Center

Enrolling by invitation

Induction and Consolidation Chemotherapy in Patients With Locally Advanced CRM-positive Rectal Cancer (RuCorT-03)

Rectal Cancer | Rectum Carcinoma | Rectal Neoplasms Malignant

Russian Federation
Blokhin's Russian Cancer Research Center

Enrolling by invitation

Neoadjuvant Chemotherapy in Patients With Moderate Risk Mid Rectal Cancer (RuCorT-02)

Rectal Cancer | Rectum Carcinoma | Rectal Neoplasms Malignant

Russian Federation
Fundación de Investigación Biomédica - Hospital...
Hospital Universitario La Fe; Hospital Alemão Oswaldo Cruz; Complejo Hospitalario...

Not yet recruiting

Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment (LORENA)

Rectal Cancer | Rectum Neoplasm
Blokhin's Russian Cancer Research Center

Enrolling by invitation

Neoadjuvant Chemotherapy in Patients With Intermediate Risk Upper and Mid Rectal Cancer (RuCorT-01)

Rectal Cancer | Rectum Carcinoma | Rectal Neoplasms Malignant

Russian Federation
Hospital Central de la Defensa Gómez Ulla
Clinica Universidad de Navarra, Universidad de Navarra

Enrolling by invitation

Patient Reported Outcomes Following Cancer of the Rectum (PROCaRe)

Rectal Cancer | PROM | Functional Bowel Disorder

Spain
Providence Health & Services
Oregon Health and Science University

Completed

Immunoscore in Rectal Cancer

Rectal Cancer | Rectal Adenocarcinoma | Cancer of the Rectum | Neoplasms, Rectal | Rectal Tumors

United States
University of Southern California
National Cancer Institute (NCI)

Withdrawn

Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal...

United States
National Cancer Institute (NCI)

Terminated

Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal...

United States
Samsung Medical Center

Unknown

Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients

Adenocarcinoma of Rectum

Korea, Republic of
Assiut University

Recruiting

Neo-adjuvant Short Course Chemo-radiation Therapy in Locally Advanced Rectal Cancer Patients

Neo-adjuvant Short Course Chemo-radiotherapy in Locally Advanced Cancer Rectum

Egypt
University Hospital Gregorio Marañón
Hospital del Río Hortega; Hospital de Leon; University of Navarrra Hospital (Clinica...

Recruiting

Patient Reported Outcomes Following Cancer of the Rectum (PROCaRe)

Rectal Cancer | Sphincter Ani Incontinence

Spain
Federation Francophone de Cancerologie Digestive
Merck Sharp & Dohme LLC; Pierre Fabre Laboratories

Recruiting

Encorafenib Plus Cetuximab in a Neoadjuvant Setting in Patients With BRAF Mutation Localised Colon or Upper Rectum Cancer (NEORAF)

Colorectal Cancer | BRAF V600E Mutation Positive

France

Clinical Trials on Cancer, Rectum

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