Clinical Trials on Cardiac Function Impaired

Total 13580 results

Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Taiho Oncology, Inc.

Completed

Evaluating Patients With Impaired Hepatic Function

Impaired Hepatic Function

United States
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Hepatic Function

Impaired Hepatic Function

United States
Tetraphase Pharmaceuticals, Inc.

Completed

A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With Impaired Hepatic Function and Healthy Subjects

Impaired Hepatic Function

United States
Repros Therapeutics Inc.

Completed

Evaluate the Safety and PK of Proellex® in Female Patients With Impaired Hepatic Function and Healthy Adults

Impaired Liver Function

United States
Alexion

Recruiting

Study of ALXN2050 in Participants With Hepatic Impairment

Healthy | Impaired Hepatic Function

United States
Royal Devon and Exeter NHS Foundation Trust
University of Exeter

Completed

Increasing Mitochondrial Function on Skeletal Muscle Performance in Older Men (Rejuvenate)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Hepatic Function

Patients With Impaired Hepatic Function

Japan
Tel-Aviv Sourasky Medical Center

Unknown

The Differential Pattern of Deposition of Nano Particles in the Airways of Exposed Workers (Nanoexposure)

Inadequate or Impaired Respiratory Function
UCB Biopharma S.P.R.L.

Terminated

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Impaired Hepatic Function | Healthy Study Participants

United States
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
University of Copenhagen
Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen

Completed

Effects of Exercise Training on Cardiovascular Health in Middle-aged Women

Cardiovascular Diseases | Metabolic Diseases | Blood Platelet Disorders | Menopause | Cardiac Function Impaired

Denmark
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Apatinib in Subjects With Impaired Renal Function

Subjects With Impaired Renal Function and Healthy Subjects
Astellas Pharma Inc

Completed

ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis

Patients With Impaired Renal Function and Haemodialysis

Japan
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
University of Exeter
Royal Devon and Exeter NHS Foundation Trust

Terminated

Assessing the Effects of Increased Mitochondrial Function Exercise Training on Muscle Performance (Rejuvenate2)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
Universidade Metodista de Piracicaba

Completed

Positive Airway Pressure Versus Breathing Exercises With Load Inspiratory in Patients Undergoing Bariatric Surgery

Inadequate or Impaired Respiratory Function

Brazil
University of Sao Paulo General Hospital

Completed

Effects of THW and rhTSH in Glomerular Filtration Rate During RIT

Other Impaired Renal Function Disorder

Brazil
Daiichi Sankyo, Inc.

Completed

A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment

Hepatic Impairment | Moderate Impaired Hepatic Function

United States
Allergan

Completed

Study of Ulipristal Acetate in Female Patients With Moderately or Severely Impaired Renal Function, Compared With Matched Healthy Female Subjects

Renal Function

United States
Modra Pharmaceuticals

Withdrawn

Oral Docetaxel in Patients With Normal or Impaired Liver Function

Solid Tumor, Adult | Impaired Liver Function

Netherlands
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
University Hospital, Grenoble

Completed

Comparison of the Effects of an Hypertonic Solution With Ringer Lactate on Right Ventricular Function Following Cardiac Surgery (SUCCESS)

Hypovolemia | Right Ventricular Impaired Function

France
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
Centre Hospitalier Régional d'Orléans

Completed

Evaluation of Whole-body CZT Camera in Gated Tomographic Radionuclide Angiography (STARGAC)

Cardiac Function

France
Assiut University

Completed

Preoperative Immunonutrition and Cardiac Patients

Cardiac Function

Egypt
University of Debrecen

Completed

Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain

Pain | Inadequate or Impaired Respiratory Function

Hungary
Óscar Cano Pérez
Spanish Society of Cardiology

Recruiting

The Left Bundle Cardiac Resynchronization Therapy Trial

Heart Failure | Left Bundle-Branch Block | Impaired Left Ventricular Function

Spain
Universidad Antonio de Nebrija

Completed

Cervical Functionality and Posture (CERFUPOS) (CERFUPOS)

People With Impaired Motor Function in the Cervical Region

Spain
NYU Langone Health

Completed

A Comparative Trial of Standard 12 Lead ECG to the 12 Lead ECG Glove to Assess Cardiac Electrical Function (HandEKG)

Cardiac Electrical Function

United States
Yangzhou University

Completed

Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period

General Anesthesia | Dexmedetomidine | Cardiac Function | Cardiac Electrophysiology

China
Al-Azhar University
University Hospital Fattouma Bourguiba

Completed

Laparoscopic Assisted Dismembered Pyeloplasty Versus Open Pyeloplasty in (UPJO) With Poorly Function Kidney in Pediatrics

Uretro-pelvic Junction Obstruction | Poorly Function Kidney

Egypt
Children's Medical Center Dallas

Completed

Compassionate Use of Omegaven in the Treatment of Parenteral Nutrition Induced Hepatic Injury

Liver Disease | Parenteral Nutrition Associated Liver Disease | Impaired Liver Function

United States
University Hospital, Linkoeping
The Swedish Research Council; Ostergotland County Council, Sweden; Pharma Nord

Completed

Intervention With Selenium and Q10 on Cardiovascular Mortality and Cardiac Function in the Elderly Population in Sweden (KiSel-10)

Cardiac Function | Cardiovascular Mortality

Sweden
VA Office of Research and Development

Active, not recruiting

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

Cognitive Function | Functional Status

United States
Universidade Metodista de Piracicaba

Completed

Effects of Respiratory Muscle Training in Obese Women

Hypertension | Diabetes | Inadequate or Impaired Respiratory Function

Brazil
China Medical University Hospital

Not yet recruiting

Effect of Electroacupuncture at Neiguan on Cardiac and Gastric Function

Cardiac and Gastric Function
Aarhus University Hospital Skejby

Completed

Conventional vs Ultrasound Guided Arteria Cannulation.

Disorder of Cardiac Function

Denmark
Radford University

Recruiting

Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men

Cardiac Function and Hemodynamics

United States
Boehringer Ingelheim

Completed

Pradaxa Study in Non-valvular Atrial Fibrillation Patients With Severely Impaired Renal Function

Atrial Fibrillation

United States
Shire

Completed

Study of SSP-004184 (FBS0701) in Healthy Adults and Elderly Subjects and in Subjects With Impaired Renal Function

Impaired Renal Function

United States
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Renal Function

Impaired Renal Function

United States
Assistance Publique - Hôpitaux de Paris

Completed

Computer Prescribing System and Impaired Renal Function (Ordoclic-IR)

Impaired Renal Function

France
Vedic Lifesciences Pvt. Ltd.
Enovate Biolife Pvt Ltd

Completed

Study to Assess the Effect of OXYJUN on Ejection Fraction and Markers of Cardiovascular Injury (Enduoxy)

Cardiac Function in Young Athletes

India
Stanford University

Terminated

Quality of Life in Adults Impaired Functioning - A Randomized Controlled Trial of Bidet vs Usual Toileting

Toileting in Adults With Impaired Functional Status | Caregiver Burden for Those Who Care for Adults With Impaired Functional Status | UTI in Adults With Impaired Functional Status

United States
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Suvorexant in Participants With Impaired Renal Function (MK-4305-023)(COMPLETED)

Insomnia

Clinical Trials on Cardiac Function Impaired

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Finland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations