Clinical Trials on Cholangiocarcinoma

Total 748 results

Nathan Bahary, MD
Bayer

Completed

A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy

Metastatic Biliary Tract Carcinoma

United States
City of Hope Medical Center

Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer (ELUCIDATE)

Hepatocellular Carcinoma | Primary Liver Cancer | Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | Hepatic Cancer | Hepatic Carcinoma | Primary Liver Carcinoma

United States, Japan
University of California, Davis
National Cancer Institute (NCI)

Recruiting

Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG) (LIVELONG)

Oligoprogressive | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Small Bowel Cancer | Intrahepatic Cholangiocarcinoma | Gall Bladder Cancer | Extrahepatic Cholangiocarcinoma | Appendiceal Cancer | Biliary Cancer | Gastroesophageal-junction Cancer

United States
Washington University School of Medicine

Active, not recruiting

Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy

Pancreatic Cancer | Pancreatitis | Pancreas Cancer | Duodenal Cancer | Ampullary Cancer | Pancreas Neuroendocrine Tumor | Distal Extrahepatic Cholangiocarcinoma

United States
iOMEDICO AG

Recruiting

Liver Cancer Registry Platform (JADE)

Hepatocellular Carcinoma (HCC) | Cholangiocarcinoma

Germany
Bing Hu

Completed

Endobiliary RFA for Unresectable Malignant Biliary Strictures

Cholangiocarcinoma | Ampullary Carcinoma

China
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Completed

A Randomized Study of GEMOX With or Without Cetuximab in Locally Advanced and Metastatic BTC (BTC)

Cholangiocarcinoma | Adenocarcinoma of Gallbladder

Taiwan
University Hospital Plymouth NHS Trust
University of Plymouth

Completed

Recurrence After Whipple's (RAW) Study

Pancreatic Cancer | Surgery | Bile Duct Cancer | Pancreatic Ductal Adenocarcinoma | Survivorship | Cholangiocarcinoma, Extrahepatic | Cancer Recurrence | Recurrent Cancer | Pancreatic Ductal Carcinoma | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampullary Cancer | Cholangiocarcinoma Resectable | Cancer... and other conditions

Spain, United Kingdom, Australia, Austria, Italy, Mexico, Sudan, Pakistan
University of Southern California
National Cancer Institute (NCI); Van Andel Research Institute

Active, not recruiting

Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer

Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7 | Recurrent Gallbladder Carcinoma | Unresectable Gallbladder Carcinoma | Recurrent Hepatocellular Carcinoma and other conditions

United States
Oslo University Hospital

Recruiting

Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy

Metastatic Colorectal Cancer | Cholangiocarcinoma | Pancreas Adenocarcinoma

Norway
Sumitomo Pharma America, Inc.

Completed

A Study of BBI503 in Adult Patients With Advanced Hepatobiliary Cancer

Hepatocellular Carcinoma | Cholangiocarcinoma

Canada
M.D. Anderson Cancer Center
Helsinn Healthcare SA

Withdrawn

Phase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion/Amplification

Cholangiocarcinoma | Liver Cancer

United States
Walid Shaib, MD
GlaxoSmithKline; Emory University

Withdrawn

Maintenance Niraparib and Dostarlimab in Advanced Cholangiocarcinoma

Metastatic Cancer | Cholangiocarcinoma | HRD
Indiana University

Completed

A Pilot Study to Assess Theragnostically Planned Liver Radiation to Optimize Radiation Therapy

Hepatocellular Carcinoma | Cholangiocarcinoma | Liver Cancer

United States
Guangzhou Medical University

Unknown

Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable Cholangiocarcinoma

Cholangiocarcinoma

China
The Second Hospital of Nanjing Medical University

Unknown

ncRNAs in Exosomes of Cholangiocarcinoma

Cholangiocarcinoma | Benign Biliary Stricture

China
Qilu Hospital of Shandong University
LanZhou University; Beijing Friendship Hospital; The Second Hospital of Hebei... and other collaborators

Recruiting

Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma

Cholangiocarcinoma | Endoscopic Retrograde Cholangiopancreatography | Klatskin Tumor | Biopsy, Fine-Needle

China
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Senior Adult Hepatobiliary Prehab Study

Cholangiocarcinoma | Liver Metastases | Hepatobiliary Cancer

United States
Toray Industries, Inc

Completed

A Study of TRK-950 in Patients With Advanced Solid Tumors

Cholangiocarcinoma | Colon Cancer | Locally Advanced or Metastatic Solid Carcinomas

France, United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Erlotinib Hydrochloride in Treating Patients With Metastatic or Unresectable Biliary Tumors

Gastrointestinal Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct | Cholangiocarcinoma of the Gallbladder

United States
Xuzhou Central Hospital

Completed

Unilateral Stenting Versus Bilateral Stenting for Malignant Hilar Biliary Obstruction

Hepatocellular Carcinoma | Cholangiocarcinoma | Gallbladder Carcinoma

China
Weill Medical College of Cornell University

Withdrawn

Comparison of Biliary Stenting Alone vs. Stenting With Photodynamic Therapy (PDT) During ERCP (PDT)

Cholangiocarcinoma

United States
Changhai Hospital
Xijing Hospital; First People's Hospital of Hangzhou; LanZhou University; Peking... and other collaborators

Withdrawn

Application of Endoscopic Scissors Cutting ENBD Tube in the Treatment of Malignant Hilar Biliary Strictures (ENBD)

Endoscopic Retrograde Cholangiopancreatography | Klatskin Tumor

China
Ruijin Hospital
Intuitive Surgical

Recruiting

Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors (PORTAL)

Pancreatic Adenocarcinoma | Chronic Pancreatitis | Ampullary Adenocarcinoma | Cholangiocarcinoma, Extrahepatic | Pancreatic Cysts | Pancreatic Endocrine Tumors | Duodenal Adenocarcinoma

China
University of Washington

Recruiting

Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma | Stage IV Liver Cancer | Stage IVA Liver Cancer | Stage IVB Liver Cancer | Vascular Thrombosis

United States
First Affiliated Hospital Xi'an Jiaotong University
First Affiliated Hospital, Sun Yat-Sen University; Shaanxi Provincial People... and other collaborators

Unknown

Superior Bilioenteric Anastomosis by Magnetic Compressive Technique (CTREG)

Hilar Cholangiocarcinoma | Bile Duct Injury | Choledochal Cyst | Biliary Calculi

China
Amsterdam UMC, location VUmc
Leiden University Medical Center; Dutch Cancer Society

Recruiting

[68Ga]Ga-FAPI-46 Positron Emission Tomography (PET) Scan to Improve the Imaging of Pancreatic and Bile Duct Cancer (PANSCAN-1)

Pancreatic Cancer | Cholangiocarcinoma

Netherlands
TransThera Sciences (Nanjing), Inc.

Active, not recruiting

Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma

Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Fusion | FGFR1 Alteration | FGFR3 Alteration

United States
Changhai Hospital

Unknown

Unilateral Versus Bilateral Stents for Bismuth Type II and III Malignant Hilar Strictures

Cholangiocarcinoma

China, Slovakia
Criterium, Inc.
University of Colorado, Denver; Novartis

Terminated

Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Cholangiocarcinoma | Esophageal Adenocarcinoma | Colorectal Adenocarcinoma | Hepatocellular Adenocarcinoma

United States
Massachusetts General Hospital
Boehringer Ingelheim; Incyte Corporation

Not yet recruiting

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

Cholangiocarcinoma | Advanced Solid Tumor | Metastatic Solid Tumor | Unresectable Solid Tumor

United States
National Cancer Institute (NCI)

Active, not recruiting

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Glioblastoma | WHO Grade 3 Glioma | Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Glioma | Recurrent Cholangiocarcinoma | WHO Grade 2 Glioma

United States
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Unknown

A Phase 1 Study of ZSP1241 in Participants With Advanced Solid Tumors

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Cholangiocarcinoma

China
Mayo Clinic
National Cancer Institute (NCI)

Completed

Sirolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients At High Risk for Cholangiocarcinoma Recurrence After Liver Transplant or Surgery

Hepatic Complication

United States
RenJi Hospital

Not yet recruiting

The Construction of Clinical Database and Multiomics Biobank Based on a Multicentral Prospective Cohort of Benign and Malignant Biliary Tract Diseases

Biliary Tract Diseases | Intrahepatic Cholangiocarcinoma | Biliary Tract Neoplasms | Gallbladder Cancer | Extrahepatic Bile Duct Cancer | Gall Stone
María Teresa Moreno Asencio

Recruiting

Analysis of the Incidence of Cholangiocarcinoma on Choledochal Cyst in a Western Center (QuiCo)

Incidence of Cholangiocarcinoma on Choledochal Cysts | Postoperative Complications in Choledochal Cysts | Choledochal Cyst Monitoring

Spain
Michael J Cavnar, MD

Terminated

Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Bile Duct Neoplasms

United States
Yonsei University

Unknown

Efficacy and Safety of Endobiliary Radiofrequency Ablation by Using a Novel RF Catheter (ELRA®) on Maintaining the Patency of Endobiliary Metal Drainage in Patients With Malignant Biliary Strictures : A Double-arm Comparable Study

Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer

Korea, Republic of
Seoul National University Hospital

Completed

Radiofrequency Ablation Using Octopus Electrodes for Treatment of Focal Liver Malignancies

Hepatocellular Carcinoma | Cholangiocarcinoma | Metastasis

Korea, Republic of
Sameek Roychowdhury

Active, not recruiting

Infigratinib for the Treatment of Advanced or Metastatic Solid Tumors in Patients With FGFR Gene Mutations

Cholangiocarcinoma | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Hepatopancreatobiliary Surgery Institute of Gansu...

Completed

Best Biliary Drainage Option in Advanced Klatskin Tumor

Cholangitis

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Intrahepatic Cholangiocarcinoma | Gallbladder Carcinoma | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Malignant Neoplasm in the Peritoneum | Distal Bile Duct Adenocarcinoma | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder...

United States
National Cancer Institute (NCI)

Completed

S0514 Sorafenib in Treating Patients With Unresectable or Metastatic Gallbladder Cancer or Cholangiocarcinoma

Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct | Cholangiocarcinoma of the Gallbladder | Adenocarcinoma of the Gallbladder | Adenocarcinoma With... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Unresectable Extrahepatic Bile Duct Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct | Cholangiocarcinoma of the Gallbladder and other conditions

United States
Washington University School of Medicine

Terminated

Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma

Liver Neoplasms | Cholangiocarcinoma

United States
Stanford University
The University of Texas Health Science Center, Houston; University of Rochester

Terminated

Comparison Bile Duct Brushings, Cholangioscopy-Directed Biopsies and Pediatric Forceps Biopsies in Biliary Strictures

Cholangiocarcinoma | Stricture; Bile Duct

United States
University of Aarhus
Danish Cancer Society

Completed

Changes in Liver Function After Stereotactic Body Radiation Therapy Measured by PET/CT

Hepatocellular Carcinoma | Cholangiocarcinoma | Metastases | Stereotactic Body Radiotherapy

Denmark
The Second Hospital of Nanjing Medical University

Unknown

Endoscopic Biliary RFA of Malignant Bile Duct Obstruction

Cholangiocarcinoma | Bile Duct Obstruction

China
New Mexico Cancer Care Alliance

Terminated

Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers (Gem-ox)

Hepatocellular Carcinoma | Bile Duct Cancer | Gallbladder Cancer | Cholangiocellular Carcinoma | Extrahepatic Bile Duct Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct | Periampullary Adenocarcinoma

United States
Zhejiang Cancer Hospital

Recruiting

Surufatinib Plus Cadonilimab in Patients With Unresectable or Metastatic Bile Duct Adenocarcinoma

Bile Duct Adenocarcinoma

China

Clinical Trials on Cholangiocarcinoma

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