Clinical Trials on Chromosome Aberrations

Total 1098 results

University Hospital, Montpellier

Unknown

Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations

Balanced Chromosomal Translocation

France
Reproductive Medicine Associates of New Jersey

Completed

Predicting Normal vs. Carrier Status in Euploid Embryos of Translocation Carriers

Balanced Chromosomal Translocation

United States
Cervesi Hospital, Cattolica, Italy

Unknown

Genomic DNA in Human Blastocoele Fluid

Chromosomal Aneuploidies | Single Gene Desease

Italy
National Cancer Institute (NCI)
Centers for Disease Control and Prevention; National Institute for Occupational...

Completed

Study of Markers of Cosmic Radiation Exposure and Effect Among Flight Crews

Frequency of Chromosome Aberrations

United States
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Preimplantation Genetic Screening in Women of Advanced Maternal Age

Chromosomal Abnormalities

Spain
KU Leuven

Unknown

Chromosomal Analysis of Single Cells in Human Embryos

Chromosomal Abnormalities

Belgium
YiYang Zhu

Unknown

Comparison of Karyotyping, CMA and NIPT for Prenatal Diagnosing Chromosomal Anomalies

Prenatal Diagnosis

China
First Affiliated Hospital Xi'an Jiaotong University

Active, not recruiting

The Value of Prenatal Ultrasound in Complicated Twin Pregnancy and Its Correlation With Chromosomal Anomalies

Complicated Twin Pregnancy

China
Maastricht University Medical Center

Withdrawn

Diagnostics for the Treatment of Progressive Mucosal Lesions of the Oral Cavity: a Prospective Study

Chromosomal Instability | Low Grade Dysplasia Oral Cavity | Loss of Heterozygostiy | Fluorescence In Situ Hybridization

Netherlands
Natera, Inc.

Completed

Non-invasive Prenatal Diagnostic Validation Study (NIPD)

Sex Chromosome Aberrations | Chromosome 13 Aneuploidy | Chromosome 18 Aneuploidy | Chromosome 21 Aneuploidy | Other Microdeletions

United States
Taizhou Hospital of Zhejiang Province affiliated...
Sir Run Run Shaw Hospital; First Affiliated Hospital of Wenzhou Medical University and other collaborators

Recruiting

Application of Chromosomal Instability in Early Diagnosis of Biliary Tract Carcinoma

Biliary Tract Carcinoma

China
Applied Spectral Imaging Ltd.

Completed

Detection of Chromosomal Aberrations in Urine Samples Using Fluorescent in Situ Hybridization (FISH) (UroVysion Test)

Bladder Cancers

United States
Federico II University

Recruiting

A Pilot Study for Implementation of First Trimester Screening of Aneuploidies in Campania Region (PISTA)

Aneuploidy

Italy
Federico II University

Completed

First Trimester Risk Assessment Based on Ultrasound and Cell-free DNA vs Combined Screening

Aneuploidy

Italy
Istanbul Medipol University Hospital

Completed

Antibiotic, Gingival-biopsy, and Oral-smear Samples.

Anti-bacterial Agents | Cytology | Histopathology | Chromosome-defective Micronuclei

Turkey
Weill Medical College of Cornell University

Completed

Polar Body Biopsy for Preimplantation Genetic Screening (Polar Body)

Aneuploidy

United States
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Aneuploidies and Different Stimulation Protocols

Aneuploidy

Spain
University College, London
British Bone Marrow Registry; Anthony Nolan Research Institute

Completed

Study on the Impact of Stem Cell Donation and Bone Marrow Harvesting on Unrelated Donors

Chromosome Aberrations
Changhai Hospital

Unknown

Application of UCAD for Diagnosing Urothelial Carcinoma.

Diagnoses Disease | Urothelial Carcinoma | Chromosomal Abnormality | Urine Marking

China
Igenomix

Completed

Clinical Value of Mosaicism Diagnosis on the Trophectoderm Biopsies (NS-MOSAICISM)

Aneuploidy | Chromosome Abnormality

Italy
Stanford University

Recruiting

Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos (TAME)

Aneuploidy | Mosaicism

United States
IVI Barcelona

Completed

Aneuploidy Rates of in Vitro Matured Oocytes (IVM)

Aneuploidy

Spain
Instituto Bernabeu

Completed

Validation of a NICS Method Using the Culture Medium

Chromosome Abnormality | Abnormality

Spain
Eyup Hakan Duran

Recruiting

Preimplantation Genetic Testing for Aneuploidy Counseling (PGT-A)

Patient Education

United States
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA; Juno Therapeutics, Inc.

Not yet recruiting

Embryos With Preimplantation Genetic Testing for Aneuploidies (PGT-A) Inconclusive Result: Clinical Implications

Embryo Disorder
The University of Hong Kong

Recruiting

RCT of niPGT for Aneuploidy and Morphology Compared With Morphology Alone in IVF

Preimplantation Diagnosis

China
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Embryo Aneuploidies and Ovarian Stimulation

Embryo Aneuploidies

Spain
Instituto Valenciano de Infertilidad, IVI VALENCIA

Terminated

Embryo Aneuploidies and Morphokinetics in Ovarian Stimulated and Non Stimulated IVF Cycles (AMOS)

Euploid Embryos

Spain
Cindy Cisneros

Completed

Development of a Prenatal Test for Fetal Aneuploidy Detection

Fetal Complications

United States
Reproductive Endocrinology Associates of Charlotte

Completed

Aneuploidy Rates in Advanced Maternal Age Patients Supplemented With Coenzyme Q10 (CoQ10) Versus Those That Are Not: a Pilot Study

Aneuploidy | Mitochondrial DNA

United States
IVI Madrid

Terminated

Aneuploidy Rate and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

Aneuploidy Rate

Spain
Al Baraka Fertility Hospital
Ibn Sina Hospital; Sadat City University

Completed

Utilizing Free DNA in Embryo Culture for PGT

Genetic Diseases, Inborn | Mutation | Chromosome Abnormalities
Center for Reproductive an Genetic Health

Unknown

The Effectiveness of Blastocentesis Versus Trophectoderm Biopsy

Abnormal Karyotype

United Kingdom
European Society of Human Reproduction and Embryology

Completed

The Eshre Study Into The Evaluation of Oocyte Euploidy by Microarray Analysis (ESTEEM)

Aneuploid Oocytes

Belgium, Germany, Greece, Israel, Italy, Spain
Bart CJM Fauser

Terminated

A Study of the Effects of a Novel Ovarian Stimulation Regimen on Embryo Aneuploidy Rates in In Vitro Fertilization (IVF)

In Vitro Fertilization

Netherlands
Wayne State University

Unknown

Prenatal Computer-Aided Genetics Education Module (CAGEM)

Aneuploidy | Autosomal Recessive Disorder

United States
Nordic MDS Group

Completed

Lenalidomide in High-risk MDS and AML With Del(5q) or Monosomy 5

AML | MDS

Denmark, Norway, Sweden
Clinique Ovo

Active, not recruiting

DFI and Aneuploidies

Embryo Disorder

Canada
Premaitha Health

Completed

A Safer Pre-Natal Diagnosis Using Free DNA in Maternal Blood (IONA)

Aneuploidy, NIPT

United Kingdom
Guangzhou Women and Children's Medical Center

Recruiting

Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies

Pregnancy | Intrauterine Growth Restriction | Fetal Anomaly | Chromosomal Anomalies

China
Shanghai First Maternity and Infant Hospital
Children's Hospital of Fudan University; International Peace Maternity and...

Unknown

Prenatal Screening, Diagnosis and Intrauterine Intervention of Fetal Abnormal Chromosome and Structure in Twins Pregnancy

Twin Pregnancy With Antenatal Problem | Chromosome Abnormality
KU Leuven

Completed

Preimplantation Genetic Screening in Women Over 35 Year

In Vitro Fertilization

Belgium
The University of Texas Health Science Center at...
National Center for Research Resources (NCRR)

Recruiting

Chromosome 18 Clinical Research Center (Chromosome18)

Growth Hormone Deficiency | Chromosome Aberrations | Hypomyelination

United States
Goethe University

Completed

Evaluation of Efficacy and Safety of Nilotinib in Combination With Chemotherapy in Elderly Patients With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Philadelphia Chromsome Positive Acute Lymphoblastic Leukemia

Spain, Germany, France
Assisting Nature

Recruiting

Invasive PGT-A Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection

Infertility | Aneuploidy | Chromosome Abnormality

Greece
Assisting Nature

Recruiting

Time Lapse Assisted Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection

Infertility | Aneuploidy | Chromosome Abnormality

Greece
Igenomix

Recruiting

RCT Study to Validate niPGT-A Clinical Benefit. (niPGT-A_RCT)

Infertility | Aneuploidy | Chromosome Abnormality

France, Argentina, Spain, United States, Brazil, Italy
Instituto Valenciano de Infertilidad, IVI Alicante
Igenomix; IVI Murcia

Terminated

Aneuploidies in Embryos and Spermatozoa From Patients With Y-chromosome Microdeletions

Male Sterility Due to Y-chromosome Deletions

Spain
Novartis Pharmaceuticals

Completed

Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome & /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic Phase ('MACS1252)

CML in Chronic Phase

Germany, Italy, Spain, Belgium, Croatia, Hungary, Netherlands, Austria, France, Greece, Sweden, Switzerland, Bulgaria, Romania, Slovenia, United Kingdom, Lithuania, Slovakia, Denmark, Finland, Norway, Poland, Czech Republic, Portugal, E... and more
Igenomix

Completed

Multi-center Study to Validate niPGT-A (niPGT-A)

Infertility | Aneuploidy | Chromosome Abnormality

Mexico, Turkey, United States, Argentina, Spain, Brazil, Italy, Peru

Clinical Trials on Chromosome Aberrations

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