Clinical Trials on Colorectal Neoplasms

Total 106683 results

National Cancer Center, Korea

Unknown

Phase II Study of Irinotecan,Oxaliplatin Plus TS-1 in Untreated Metastatic Colorectal Cancer (TIROX2)

Colorecal Neoplasms | Secondary

Korea, Republic of
Chinese University of Hong Kong

Recruiting

The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong (ACNC)

Colorectal Cancer | Colorectal Neoplasia

Hong Kong
Bristol-Myers Squibb
Novartis

Active, not recruiting

An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread (CheckMate 9N9)

Colorectal Cancer | Colorectal Neoplasm | Colorectal Tumors | Colorectal Carcinoma

Italy, United States, Canada, Spain, Argentina, Australia, Belgium, Chile, Czechia, Germany
Hôpital Edouard Herriot

Completed

Endoscopic Characterization of Colorectal Neoplasia With the Different Published Classifications

Colorectal Neoplasia

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Lung | Resectable Colorectal Carcinoma

United States
Koen Rovers
Hoffmann-La Roche; Comprehensive Cancer Centre The Netherlands; Dutch Cancer...

Recruiting

Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases (CAIRO6)

Colorectal Cancer | Peritoneal Neoplasms | Colorectal Neoplasm | Peritoneal Carcinomatosis | Colorectal Carcinoma | Peritoneal Cancer | Peritoneal Metastases | Colorectal Adenocarcinoma | Colorectal Neoplasms Malignant | Peritoneal Neoplasm Malignant Secondary Carcinomatosis | Peritoneal Neoplasm Malignant...

Netherlands, Belgium
Hospital Clinic of Barcelona
Instituto de Salud Carlos III; Grupo Cooperativo para el Cribado del Cancer... and other collaborators

Completed

Colorectal Cancer Screening in Average-risk Population: Immunochemical Fecal Occult Blood Testing Versus Colonoscopy

Colorectal Cancer | Colorectal Neoplasm

Spain
Inova Health Care Services
Novartis Pharmaceuticals

Completed

New Individualized Therapy Trial for Metastatic Colorectal Cancer (NITMEC)

Colorectal Cancer | Colorectal Neoplasm

United States
Kaiser Permanente
The Permanente Medical Group

Withdrawn

Predicting Risk for Post-polypectomy Colorectal Cancer (PREDICT)

Colorectal Cancer | Colorectal Adenoma | Colorectal Polyp | Neoplasm, Colorectal

United States
Universitätsklinikum Hamburg-Eppendorf

Terminated

Piecemeal Versus En Bloc Resection of Large Rectal Adenomas (PERLA)

Colorectal Adenomatous Polyp | Colorectal Adenoma With Mild Dysplasia | Colorectal Adenoma With Severe Dysplasia | Colorectal Low Grade Intraepithelial Neoplasia | Colorectal High Grade Intraepithelial Neoplasia

Germany, United Kingdom
National Taiwan University Hospital

Unknown

Application of CO2 Insufflations in Colonoscopy Randomized Trial

Colorectal Cancer | Colorectal Neoplasm

Taiwan
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Gut Microbiome in Colorectal Cancer (GO)

Gastrointestinal Microbiome | Neoplasm, Colorectal

United States
NuCana plc

Active, not recruiting

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Neoplasm, Colorectal

United States, Spain, United Kingdom, Italy, Germany, France
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Genentech, Inc.

Active, not recruiting

Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | BRAF NP_004324.2:p.V600X | KRAS wt Allele

United States
University of Washington
National Cancer Institute (NCI)

Completed

Colorectal Cancer Screening Intervention in UWPN Clinics

Colorectal Neoplasia

United States
Istituto Clinico Humanitas

Completed

Non-cathartic Computed Tomographic Colonography to Screen Subjects With a Family History of Colorectal Cancer

Colorectal Neoplasia

Italy
National Cancer Institute (NCI)

Active, not recruiting

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Stage IIIA Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Solid Neoplasm

United States, Canada
University of Aarhus
Aarhus University Hospital

Recruiting

DANISH.MRD: Danish Assessment of Minimal Residual Disease by Liquid Biopsies (DANISH_MRD)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage I

Denmark
Carol Davila University of Medicine and Pharmacy

Recruiting

Endoscopic Submucosal Dissection Registry (ESDREG)

Neoplasm, Colorectal | Neoplasm, Stomach | Neoplasm, Esophagus | Neoplasm, Duodenal

Romania
South Tyneside and Sunderland NHS Foundation Trust
Newcastle University

Recruiting

COLO-COHORT (Colorectal Cancer Cohort) Study

Colorectal Cancer | Colorectal Neoplasm | Colorectal Adenoma | Predictive Cancer Model | Model

United Kingdom
National Cancer Institute (NCI)

Recruiting

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

Colorectal Cancer | Liver Metastases | Colorectal Carcinoma | Colorectal Adenocarcinoma | Colorectal Cancer With Hepatic Metastases

United States
Shandong University

Completed

A New Quantitative Fecal Immunochemical Test in Detecting Colorectal Advanced Adenoma

Colorectal Cancer | Colorectal Neoplasm | Colorectal Adenoma

China
Grupo Espanol Multidisciplinario del Cancer Digestivo
Amgen; Pivotal S.L.

Completed

FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status (OPALO)

Neoplasm Metastasis | Colorectal Neoplasms | Colorectal Cancer Metastatic | Colorectal Carcinoma

Spain
Intuitive Surgical

Completed

A Prospective Single-Center Evaluation of SureForm™ Staplers in Robotic-assisted Colorectal Procedures

Benign Colorectal Neoplasm | Benign Colon Tumor | Malignant Colorectal Tumor

United States
London North West Healthcare NHS Trust
St Mark's Foundation

Completed

Optimisation and Performance of Reduced Preparation CT Colography

Patients With Potential Colorectal Neoplasia

United Kingdom
M.D. Anderson Cancer Center

Recruiting

An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Resectable Colorectal Carcinoma

United States
Chloe Atreya, MD, PhD
Merck Sharp & Dohme LLC; MedPacto, Inc.

Recruiting

Preoperative Immunotherapy (Pembrolizumab) for Patients With Colorectal Cancer and Resectable Hepatic Metastases

Metastatic Malignant Neoplasm in the Liver | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

United States
Transgene

Terminated

Study of TG6002 (VV TK-RR-FCU1) in Combination With 5-FC in Patients With Advanced Gastro-intestinal Tumors.

Colorectal Neoplasm | Digestive System Neoplasm

France, Spain, Belgium
Zealand University Hospital

Recruiting

NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer (NEOLAR)

Intestinal Neoplasms | Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colorectal Neoplasm | Chemotherapy Effect | Intestinal Disease

Denmark
City of Hope Medical Center

Recruiting

Early Onset Colorectal Cancer Detection (ENCODE)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage IV | Colorectal Neoplasms Malignant | Colorectal Cancer Stage I

United States, Japan, Italy, Spain
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
NuCana plc

Completed

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States, France, United Kingdom
Arjun Mittra
National Cancer Institute (NCI)

Recruiting

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Peritoneum

United States
Emory University
Bristol-Myers Squibb; National Cancer Institute (NCI); National Institutes of...

Active, not recruiting

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Refractory Colorectal Carcinoma | Metastatic Microsatellite Stable Colorectal Carcinoma | Stage IVC Colorectal Cancer

United States
Ruijin Hospital
HuaDao (Shanghai) Biomedical Co., Ltd.

Not yet recruiting

A Clinical Research of CAR T Cells Targeting CEA Positive Colorectal Cancer (CRC) (CRC)

Stage III Colorectal Cancer | Colorectal Cancer Liver Metastasis
The Queen Elizabeth Hospital
Novartis; Amgen

Completed

Safety Study of the Combination of Panitumumab, Irinotecan and Everolimus in the Treatment of Advanced Colorectal Cancer (PIE)

Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

Australia
Novartis Pharmaceuticals

Completed

A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal Cancer

Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States
ProgenaBiome

Recruiting

A Pilot Study to Explore the Role of Gut Flora in Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Cancer Metastatic | Colorectal Carcinoma | Colorectal Adenocarcinoma | Colorectal Sarcoma

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Safety and Efficacy of Reduced-port Laparoscopic Surgery for Patients Of Colon and Upper Rectal Cancer

Colorectal Neoplasm

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Fruquitinib Combined With Camrelizumab in Non MSI-H/dMMR Refractory Colorectal Cancer

Colorectal Neoplasm

China
University of New Mexico
National Cancer Institute (NCI)

Active, not recruiting

Enhancing Prevention Pathways Toward Tribal Colorectal Health

Colorectal Neoplasm

United States
GSO Global Clinical Research BV
Karyopharm Therapeutics Inc

Terminated

Phase 1 Trial To Evaluate mFOLFOX6 With Selinexor In Patients With Metastatic Colorectal Cancer (SENTINEL)

Colorectal Neoplasm

Germany, Belgium
Daiichi Sankyo Co., Ltd.
AstraZeneca; Daiichi Sankyo, Inc.

Completed

DS-8201a in Human Epidermal Growth Factor Receptor2 (HER2)-Expressing Colorectal Cancer (DESTINY-CRC01)

Colorectal Neoplasm

United States, Spain, Japan, Italy, United Kingdom
Isofol Medical AB

Completed

Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer

Colorectal Neoplasm

Denmark, Norway, Greece, Sweden
Konkuk University Hospital

Completed

The Usefulness of I-scan in Screening Colonoscopy

Colorectal Neoplasm

Korea, Republic of
Fudan University

Unknown

Recombinant Human Endostatin in Combination With mFOLFOX6 in Patients With Metastatic Colorectal Cancer

Colorectal Neoplasm

China
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
Pawel Kalinski
National Cancer Institute (NCI)

Completed

Safety of Labeled Dendritic Cell (DC) Vaccines and Feasibility of Tracking by Magnetic Resonance Imaging (MRI)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States
Jeremy Meyer
University Hospital, Geneva; Hôpital Fribourgeois; Spital Biel, Switzerland

Not yet recruiting

Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy (PRORHEM)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Adenocarcinoma | Colorectal Polyp | Colorectal Neoplasms Malignant | Colorectal Neoplasms, Benign

Clinical Trials on Colorectal Neoplasms

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