Clinical Trials on Congenital Malformations

Total 8797 results

Centre Hospitalier Universitaire Dijon

Recruiting

Evaluation of Rapid First-line Genome Sequencing for Prenatal Diagnosis of Congenital Malformations in Comparison With Chromosomal Microarray and Exome Sequencing (PRENATOMEultra)

Congenital Malformation

France
Rennes University Hospital

Completed

Pregnancy Environment and Newborn Malformations (PENEW)

Congenital Malformation

France
University of Michigan

Enrolling by invitation

Dynamic MRI and Quantitative MR CSF Flow Studies in Craniovertebral Junction Anomalies

Chiari Malformations
King's College Hospital NHS Trust
King's College London

Completed

A Review of Surgical Management of Congenital Pulmonary Airway Malformations (CPAM): A Decade of Experience (CPAM)

Congenital Disorders | Pulmonary Arteriovenous Malformation

United Kingdom
Orfagen
FDA Office of Orphan Products Development

Completed

Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study.

Congenital Venous Malformation

United States, France
Children's Hospital of Fudan University
Second Affiliated Hospital of Wenzhou Medical University; Guangzhou Women and... and other collaborators

Recruiting

Genomic Sequencing and Personalized Treatment for Birth Defects in Neonatal Intensive Care Units

Genetic Disease | Congenital Malformation | Multiple Malformation

China
West China Hospital
Xiamen Health Commission; Xiamen Health and Medical Big Data Center

Completed

A Population-based Study of Drug Exposures and Adverse Pregnancy Outcomes in China (DEEP)

Pregnancy | Congenital Malformation | Drug Exposure

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Identification of Genetic Mutations Involved in Chiari Type I Malformations (ChiariGene)

Chiari Malformation, Type 1

France
Assiut University

Recruiting

Modalities of Surgical Treatment of Chiari Malformation Disease : Clinical Study and Outcomes

Chiari Malformation, Type 1

Egypt
University of Illinois at Chicago

Completed

Duragen Versus Duraguard in Chiari Surgery

Chiari Malformation

United States
Xuanwu Hospital, Beijing

Recruiting

PFDD Versus PFDRT in Chiari Decompression Surgery

Tonsillectomy | Chiari Malformation Type I

China
Hacettepe University

Recruiting

Investigation of the Effects of Exercise Program in Patients With Chiari Type 1 Malformation

Arnold Chiari Malformation

Turkey
Al-Azhar University

Completed

Treatment of Venous Malformation

Venous Malformation

Egypt
Duke University

Completed

The Genetics of Chiari Type I Malformation

Chiari Type I Malformation

United States
Hospices Civils de Lyon

Not yet recruiting

Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection (3DLP)

Pulmonary Malformation

France
University Hospital, Toulouse

Completed

Electromagnetic Navigation During Ultrasound Guided Foam Sclerotherapy for Venous Malformations (SCLERONAV)

Venous Malformation

France
Suez Canal University

Completed

Complications of Ethanol-amine Oleate Intralesional Sclerotherapy

Venous Malformation

Egypt
Oslo University Hospital

Active, not recruiting

Compare Two Different Sclerosing Agents in the Treatment of Venous Malformations

Venous Malformation

Norway
Carmel Medical Center

Unknown

Cohort Prospective Study of Children With Head and Neck Cystic Malformation Who Are Treated With Intracystic OK432 (OK432)

CYSTIC MALFORMATION

Israel
Mayo Clinic

Completed

Genetic Variants in Nicotinamide Adenine Dinucleotide (NAD) Synthesis Pathway

Congenital Malformation | Vacterl Association

United States
Central Hospital, Nancy, France
University of Lorraine

Unknown

Postual Control in Pediatric Chiari I Malformation

Pediatric | Chiari I Malformation

France
University Hospital, Bordeaux

Completed

Arnold Chiari Malformation: the Otological Assessment as an Objective Criteria for Surgical Treatment (MCoto)

Arnold-Chiari Malformation, Type 1

France
Assistance Publique - Hôpitaux de Paris

Completed

Genetic and Molecular Abnormalities in Congenital Cystic Adenomatoid Malformations (MAKP)

Congenital Cystic Adenomatoid Malformation (CCAM)

France
University of Alberta

Withdrawn

Initiation of Resuscitation While Attached to the Cord With Congenital Heart Disease (INSPIRE-CHD)

Hypoplastic Left Heart Syndrome | Congenital Heart Defect | TGA - Transposition of Great Arteries | Congential Absence of Heart Structure | Congenital Malformation of Heart, Unspecified | Hypoplastic Right Heart Syndrome | Congential Malformations of Aortic Valve | Congential Malformations of Great...

Canada
Venthera, Inc., a BridgeBio company

Terminated

First in Human Trial of Topical VT30 in Pts With Venous/Lymphatic Malformations Assoc With PIK3CA or TEK Gene Mutations

Lymphatic Malformation | Venous Malformation | Venolymphatic Malformation

United States
University Hospital, Tours

Completed

suPERficial Slow-flow Vascular malFORMations Treated With sirolimUS (PERFORMUS)

Vascular Malformation

France
Stanford University
Boston Children's Hospital

Recruiting

Trametinib in the Treatment of Complicated Extracranial Arterial Venous Malformation

Arterial Disease | Venous Malformation

United States
Yonsei University

Completed

Urodynamic Evaluation in Patients With Anorectal Malformation According to Spinal Cord Abnormalities

Anorectal Malformation

Korea, Republic of
China Medical University Hospital
Academia Sinica, Taiwan

Unknown

Genomic Study of Congenital Malformation

Genomic Aberrations in Patients Diagnosed as Congenital Malformation With Unknown Etiology

Taiwan
Assiut University

Unknown

Laparoscopically Assisted Anorectal Pull-through Versus Posterior Sagittal Anorectoplasty

Anorectal Malformation
St. Luke's-Roosevelt Hospital Center

Completed

Safety of Apollo Micro Catheter in Pediatric Patients

Brain Arteriovenous Malformation | Brain Vascular Malformations | Vein of Galen Malformation

United States
Johns Hopkins University

Recruiting

Patient Reported Outcomes for Vascular Malformations EmbolizatioN (PROVEN)

Vascular Malformations | VM - Vascular Malformation

United States
University Hospital Erlangen

Completed

Influence of Flat-knitted Compression Stockings Class I and II on Venous Malformations

Vascular Diseases | Vascular Malformations | Venous Malformation | Vascular Malformation Peripheral

Germany
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Development of a Patient-reported Outcome Measure for Chiari Malformation and Syringomyelia (BCS-score)

Syringomyelia | Chiari Malformation

France
Washington University School of Medicine
Patient-Centered Outcomes Research Institute; Mayo Clinic; The University of... and other collaborators

Completed

Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia

Syringomyelia | Arnold-Chiari Malformation, Type 1 | Chiari Malformation Type I | Type I Arnold-Chiari Malformation

United States
University Hospital, Lille
University of Lille Nord de France

Completed

The Impact of the Birth of a Child With a Rare Abdomino-thoracic Malformation (INEMAT)

Congenital Malformation

France
University Hospital, Limoges

Recruiting

Impact of CErebral Endovascular PROcedures on the Systemic Immune responSe Response (PROCESS)

Cerebral Arterio-venous Malformation

France
National Institute of Neurological Disorders and...

Completed

Genetic Analysis of the Chiari I Malformation

Syringomyelia | Type I Arnold Chiari Malformation

United States, Russian Federation
Imagine Institute

Completed

Computational Anatomy in Surgery for Childhood Tumours and Malformations (IMAG2)

Tumor | Malformation | Paediatric Surgery | 3D Imaging

France
USFetus
University of Southern California; Wellington Hospital

Recruiting

Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele

Neural Tube Defects | Myelomeningocele | Spina Bifida | Chiari Malformation

United States
First Affiliated Hospital, Sun Yat-Sen University

Unknown

Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery

Arteriovenous Malformation

China
Erasmus Medical Center

Recruiting

The COllaborative Neonatal Network for the First CPAM Trial (CONNECT)

Congenital Pulmonary Airway Malformation

Netherlands
Medical University of South Carolina

Recruiting

Weekly Sirolimus Therapy

Lymphatic Malformation | Venous Malformation

United States
Balgrist University Hospital

Completed

Measurements Of Lower Limbs And Spine Based On Biplanar Radiographs: Microdose Compared To Standard Dose Protocol

Scoliosis | Underdevelopment; Congenital Malformation, Lower Limb

Switzerland
St. Joseph's Hospital and Medical Center, Phoenix

Completed

Dural Graft Equivalent Comparison Trial (DECOMPRESS)

Chiari Malformation

United States
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Comparison of Two Protocols of Optimization of X Ray Radiations in Pediatric Interventional Neuroradiology (MINIRAD)

Occlusion or Malformation of a Cerebral Vessel

France
National Health Service, United Kingdom

Unknown

Assessing the Effects of Air-cooling on Capillary Malformations

Laser | Capillary Malformation | Skin Cooling

United Kingdom
Odense University Hospital
Aarhus University Hospital; University of Southern Denmark

Unknown

Long-term Outcome in Patients With Anorectal Malformations (LOPAM)

Anorectal Malformation
Shanghai Jiao Tong University School of Medicine

Unknown

the Efficiency of Endoscopic Treatment for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation

Gastrointestinal Vascular Malformation

China
Sohag University

Recruiting

Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations

Vascular Malformations | Microcystic Lymphatic Malformation | Combined Vascular Malformation

Egypt

Clinical Trials on Congenital Malformations

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Rare Diseases

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