Clinical Trials on Dose-escalation
Total 8784 results
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Esperion Therapeutics, Inc.CompletedSafety Evaluation of Escalating DosesUnited States
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BeiGeneRecruitingLocally Advanced or Metastatic Solid Tumors for Phase 1,Dose Escalation and Phase 2 Safety Lead-in, HNSCC, NSCLC and RCC Participants for Phase 2Australia, United States, Spain, France, Italy, Korea, Republic of, Poland
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OnxeoSpectrum Pharmaceuticals, IncCompletedDose Escalation: Solid Tumors | MTD: Soft Tissue SarcomasDenmark, United Kingdom
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University Hospital OlomoucUniversity Hospital Ostrava; Masaryk Memorial Cancer InstituteRecruitingHypoxia | Head and Neck Cancer | Dose Escalation | FMISOCzechia
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Asan Medical CenterRecruitingQuality of Life | Prostate Cancer | Radiation Toxicity | Biochemical Recurrence | Survival | Radiation | Hypofractionation | Dose EscalationKorea, Republic of
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Bergen University CollegeHelse-Bergen HFCompleted
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Ruijin HospitalRecruitingEsophageal Cancer | Salvage Radiotherapy | Dose-escalation | Mediastinal Lymph Node RecurrenceChina
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Hadassah Medical OrganizationNexcella, IncRecruiting
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Radboud University Medical CenterTerminatedStage III Non-small Cell Lung Cancer | Individualized Radiation Dose EscalationNetherlands
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Shandong New Time Pharmaceutical Co., LTDRecruitingDose-Escalation Study, Relapsed or Refractory Multiple MyelomaChina
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Fudan UniversityUnknownOropharyngeal Carcinoma | De-escalationChina
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Fudan UniversityRecruitingOropharyngeal Carcinoma | Immune Checkpoint Inhibitor | De-escalationChina
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University of Alabama at BirminghamAmerican Cancer Society, Inc.CompletedDecision Making ,Shared | De-escalationUnited States
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Sun Yat-sen UniversityFirst Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Hunan Cancer... and other collaboratorsRecruitingNasopharyngeal Carcinoma | De-escalation TherapyChina
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ModernaTX, Inc.AstraZenecaActive, not recruitingDose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma | Dose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC LymphomaUnited States, Israel, Australia
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Sun Yat-sen UniversityFirst Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern... and other collaboratorsRecruitingNasopharyngeal Carcinoma | De-escaltion TherapyChina
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University of RochesterAgency for Healthcare Research and Quality (AHRQ)CompletedCompletion of Three Dose Series of HPV | Improvement in Vaccine Intervals Between HPV DosesUnited States
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Dr. Reddy's Laboratories LimitedCompletedRapidly Escalating MigraineUnited States
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Shenyang Northern HospitalNot yet recruitingST Elevation Myocardial Infarction | Dual Antiplatelet Therapy | Optical Coherence Tomography | Antiplatelet De-escalation | Neointimal CoverageChina
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Washington University School of MedicineCompletedSeptic Shock | Severe Sepsis | Respiratory Arrest | Cardiopulmonary Arrest | Escalation of CareUnited States
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Pepperdine UniversityRecruitingHigh Nitrate Dose | Moderate Nitrate Dose | Low Nitrate Dose | Nitrate-depleted DoseUnited States
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Novartis PharmaceuticalsTerminatedIn Escalation: All Patients With Solid Tumors and Lymphoma | In Expansion: Melanoma, Non-small Cell Lung CancerUnited States, Italy, Taiwan, Belgium, Spain, Germany, Japan
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Northumbria UniversityCompletedLow Fat Meal - Unadjusted Insulin Dose | High Fat Meal - Unadjusted Insulin Dose | High Fat Meal - Adjusted Insulin Dose +30 Percent | High Fat Meal - Adjusted Insulin Dose +Split Dose
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Fujian Akeylink Biotechnology Co., Ltd.The First Hospital of Jilin UniversityRecruitingPharmacokinetics | Food Affect | Single Ascending Dose | Maximum Applicable DoseChina
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Hospital Geral de FortalezaUnknown
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Chulalongkorn UniversityHIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...RecruitingSafety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...Thailand
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University of California, Los AngelesWithdrawn7-dose Control - Progressive Muscle Relaxation Only | 5-dose - Pairs Progressive Muscle Relaxation With Fruit 5 Consecutive Days | 7-dose - Pairs Progressive Muscle Relaxation With Fruit 7 Consecutive Days | 9-dose - Pairs Progressive Muscle Relaxation With Fruit 9 Consecutive Days
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Medical University of South CarolinaCompleted
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TakedaCompletedDose Finding StudyUnited States
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TakedaCompletedDose Finding StudyUnited States
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TakedaCompleted
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Sixth Affiliated Hospital, Sun Yat-sen UniversityNot yet recruitingPreoperative | Midazolam | DoseChina
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Duke UniversityTerminatedSplit Dose CTUnited States
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Spherium BiomedHospital Universitario La PazCompletedSafety, Tolerability and Pharmacokinetic Profile of an Infusion of Cilastatin in Healthy Volunteers.Dose Finding StudySpain
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TakedaCompleted
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TakedaRichmond Pharmacology LimitedCompleted
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Novartis PharmaceuticalsCompletedMetastatic Colorectal Cancer | Gastric Cancer | Advanced Solid Tumors | Metastatic Breast Cancer | Gastroesophageal Junction Cancer | Recurrent Glioblastoma Multiforme | Advanced Pancreatic Adenocarcinoma | Safety | Triple Negative Metastatic Breast Cancer | Dose Escalation | Preliminary Efficacy | Hormone Receptor...Canada, United Kingdom, Spain, Germany, Italy, Belgium, Australia, United States
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Mayo ClinicRecruitingShivering | Dose Finding StudyUnited States
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TakedaCompletedAscending Single Dose Study
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Guangzhou Women and Children's Medical CenterUnknownDose-Response Relationship, Drug
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Rambam Health Care CampusCompleted
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Peking University Third HospitalNot yet recruitingHysteroscopic Surgery | Etomidate Induced Dose
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University of MemphisUniversity of Tennessee Health Science Center; USP Labs, Inc.Completed
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Erzurum Regional Training & Research HospitalKaradeniz Technical UniversityCompletedResearch on the Effectiveness of a Corticosteroid, Single Dose and Three Doses of Ozone Injection in Shoulder Impingement SyndromeTurkey
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University of LiegeNot yet recruitingProtamine Adverse Reaction | Protamine Dose
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Philips Electronics Nederland B.V. acting through...Leiden University Medical CenterTerminated
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Guangzhou Women and Children's Medical CenterCompleted
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University Hospital, BrestCompletedMeasure of the X-ray DoseFrance
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Malmö UniversityCompletedLow-Dose CBCT Protocol for Pre-Surgical Evaluation of the Mandibular Third Molar, a Feasible Choice?Cone Beam Couputed Tomography, Dose ReductionSweden
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Astellas Pharma Europe B.V.CompletedHealthy Subjects | Pharmacokinetics | EC905 | Multiple DoseUnited Kingdom