Clinical Trials on Drug Drug Interactions

Total 3195 results

Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Ketoconazole on the Pharmacokinetics of NKTR-118

Healthy Volunteers | Bioavailability | Drug- Drug Interactions

United States
Jemincare

Completed

A DDI Study of JMKX000623 and Metformin Hydrochloride

Healthy | Drug-Drug Interaction

China
KBP Biosciences
Covance

Completed

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Healthy | Drug Drug Interaction

United States
University of Southern Denmark
SignaTope GmbH, Germany

Completed

Flucloxacillin as an Inducer of CYP-enzymes

Healthy Volunteers | Drug Drug Interaction

Denmark
University Hospital, Basel, Switzerland

Completed

Pharmacokinetic Interactions of Metamizole (Dipyrone) in Healthy Subjects

Inhibition | Drug-Drug Interaction | Induction

Switzerland
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
Johns Hopkins University
Washington State University; National Center for Complementary and Integrative...

Completed

Interactions Between Cannabinoids and Cytochrome P450-Metabolized Drugs

Drug-Interactions

United States
Biogen

Completed

A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen

Drug Interactions

United States
GlaxoSmithKline

Completed

Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation

Drug Interactions

Korea, Republic of
Gerd Mikus

Completed

Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

Drug Interactions

Germany
Gerd Mikus

Completed

Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan

Drug Interactions

Germany
Lexicon Pharmaceuticals

Completed

Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects

Drug Interactions

United States
Gebro Pharma GmbH

Completed

S(+)-Ibuprofen Effects on Asprin Treated Volunteers

Drug Interactions

Austria
Universidad Nacional de Córdoba

Unknown

Study for Early Detection of Drug Interactions in Older Hospitalized Patients Using on Line Software (SEDDI)

Drug Interactions

Argentina
University Hospital Inselspital, Berne

Completed

Effect of Fluvastatin on Top of Clopidogrel and Aspirin in Patients After DES Implantation on Platelet Aggregation (EFA-1)

Drug-Interactions

Switzerland
Guangdong Raynovent Biotech Co., Ltd

Completed

A Drug Interaction Study Assess the Effects of ZSP1273 Tablets on the Pharmacokinetics of Warfarin and Midazolam

Warfarin | Drug Drug Interaction | Midazolam

China
University of Southern Denmark

Completed

The Effect of Dicloxacillin on Oral Absorption of Drugs

Healthy Volunteers | Drug-drug Interaction

Denmark
Biota Scientific Management Pty Ltd

Completed

A Drug-Drug Interaction Study to Evaluate the Effect of Vapendavir on the Pharmacokinetics of Midazolam in Healthy Male and Female Volunteers

Drug-Drug Interaction Healthy Volunteers

United States
CTI BioPharma
PPD

Completed

Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

Drug Interactions

United States
Seoul National University Bundang Hospital

Enrolling by invitation

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Methotrexate in Elderly Subjects

Drug Interactions

Korea, Republic of
Nanjing Sanhome Pharmaceutical, Co., Ltd.

Completed

A Drug-drug Interaction Study of SH229 Tablets and Daclatasvir Dihydrochloride Tablets in Healthy Subjects

Drug Interactions

China
Bayer

Completed

Study to Learn More About the Effect of Itraconazole (ITZ) Given Repeatedly by Mouth on the Way How the Study Drug BAY1902607 Given One Time by Mouth Acts in the Human Body of Healthy Male Participants

Drug Interactions

Germany
Gerd Mikus

Completed

Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Bosentan Before and During Clarithromycin

Drug Interactions

Germany
Vertex Pharmaceuticals Incorporated

Completed

Phase 1 PK Interaction Study Between VX-509 and Prednisone or Methylprednisolone in Healthy Male Subjects

Drug Interactions

United States
Abbott

Completed

A Study to Evaluate the Interaction Between Vicodin® CR and Ethanol in Healthy Male and Female Moderate Alcohol Drinkers

Drug Interactions

Canada
Emalex Biosciences Inc.
Syneos Health; Nuventra

Terminated

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Drug-Interactions

United States
Bayer

Completed

Microgynon Riociguat Drug Interaction Study in Healthy Postmenopausal Women

Drug Interactions

Germany
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
Bayer

Completed

Effect of Ketoconazole on the Pharmacokinetics of Refametinib

Drug Interactions

United States
University of Tennessee

Completed

Alcohol Inhibits Drug Metabolism by Carboxylesterases

Drug Interactions

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-Drug Interaction of Pyrotinib With a Moderate CYP3A Inducer

Healthy Subjects, Drug-drug Interaction, Pyrotinib

China
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction

France
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Drug-Drug Interaction (DDI)

France
Taipei Veterans General Hospital, Taiwan

Completed

Modeling and Application of Triple Drug Response Surface Models

Pharmacodynamics | Drug Interactions

Taiwan
University of Washington
Fred Hutchinson Cancer Center; National Institute of General Medical Sciences...

Completed

Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions

Adverse Drug Interactions

United States
Lawson Health Research Institute

Completed

Coffee Interaction With the Antihypertensive Drug Felodipine

Food-Drug Interactions

Canada
University of Utah
Cubist Pharmaceuticals LLC

Completed

Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin

Pharmacokinetics | Drug Interactions

United States
University of Illinois at Chicago

Completed

Hop Botanical Dietary Supplements - Metabolism and Safety in Women

Food-Drug Interactions

United States
Melinta Therapeutics, Inc.

Completed

Study to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects

VA Drug Interactions

United States
Xspray Pharma AB
Axis Clinicals Limited

Completed

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Pharmacokinetics | Drug Interactions

United States
Medical University of South Carolina
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Drug Interactions and Bioavailability of Cranberry

Healthy | Drug Interactions

United States
Boryung Pharmaceutical Co., Ltd

Completed

Drug Interaction Study of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects

Drug-Drug Interaction

Korea, Republic of
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of Quizartinib on the Pharmacokinetics of the P-gp Substrate Dabigatran Etexilate in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany

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