Clinical Trials on Drug Mechanism

Total 3174 results

University of Cincinnati
Children's Hospital Medical Center, Cincinnati

Completed

Pharmacokinetics and Pharmacodynamics of Extended-Infusion Cefepime in Continuous Renal Replacement Therapy

Drug Mechanism
Nova Scotia Health Authority

Unknown

In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects

Drug Mechanism

Canada
Johanna Kujala

Completed

Detection of Paracetamol Concentration in Blood-, Saline- and Urine Samples - a Validation Study for a Novel Technique

Healthy | Drug Mechanism

Finland
Bezmialem Vakif University

Completed

Does Vildagliptin Affect Portal Vein Pressure In Patients With Type 2 Diabetes Mellitus? A Cross Sectional Study

Drug Usage | Drug Mechanism

Turkey
University of Wisconsin, Madison

Completed

The Effects of Mindfulness Training on Pain Regulation, Negative Affect, Attention, and Social Stress

Focus on Pain Regulation Mechanisms | Social Stress Mechanisms | Basic Affective Mechanisms | Attention Mechanisms | Brain Mechanisms | Immune Mechanisms | Endocrine Mechanisms

United States
Brigham and Women's Hospital
Harvard Medical School (HMS and HSDM)

Recruiting

Revisiting the Mechanism of the Anti-inflammatory Effect of Colchicine

Colchicine Mechanism of Action

United States
Rigshospitalet, Denmark

Recruiting

The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling

Major Depressive Disorder | Sexual Behavior | Mood Change | Mood Disturbance | Affect Altered | Affect Blunted | Drug Mechanism

Denmark
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Topical Formulations of Liposomal Local Anesthetics

Administration, Topical | Administration, Topical Drug | Anesthetic Drugs

Brazil
Xiangya Hospital of Central South University

Unknown

Study on the Neurovascular Coupling Function in Patients Undergoing Cardiac Surgery

Neurovascular Coupling Mechanism and Cognitive Function
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Remimazolam Improves the Safety in Elderly Patients Undergoing Gastrointestinal Endoscopy

Recovery | Drug Effect | Safety | Psychotropic Drugs | Anesthetics, Intravenous | Anesthetics

China
KU Leuven

Recruiting

Understanding the Neural Mechanisms Behind tDCS

tDCS Mechanisms

Belgium
Rutgers, The State University of New Jersey

Completed

The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota

Mechanisms, Defense

United States
University Hospital, Tours

Not yet recruiting

Development and Qualification of Methods for Analyzing the Mucosal Immune Response to COVID-19 (MUCOVID)

Certain Disorders Involving the Immune Mechanism

France
California Pacific Medical Center Research Institute

Completed

Role of Serotonin in Acute and Subacute MDMA Effects

MDMA Mechanism of Action

United States
China Medical University, Taiwan
Ministry of Science and Technology, Taiwan

Recruiting

The Effect of Laser Acupuncture in Different Meridians on the Autonomic Nervous System and Its Brain Mechanisms

Heart Rate Variability | Laser Acupuncture | Meridian | Brain Mechanism

Taiwan
Albert Einstein College of Medicine

Completed

Studies of Sulfur Metabolism in Humans

Metabolic Side Effects of Drugs

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Molecular Basis of Human Phagocyte Interactions With Bacterial Pathogens

Host Defense Mechanisms

United States
Christian Ruff

Not yet recruiting

Brain Network Mechanisms Causally Underlying Human Decisions Revealed by Brain Stimulation and Functional MRI

Behavior and Behavior Mechanisms
Duke University

Terminated

Fathers Raising Responsible Men (FRRM): Addressing Sexual Health (FRRM)

Behavior and Behavior Mechanisms

United States
New York University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Couple & Family Contexts (CFC)

Behavior and Behavior Mechanisms

United States
Hôpital le Vinatier

Recruiting

Impact of Another Person's Presence on Brain and Behavioral Performance (SOFEE)

Behavior and Behavior Mechanisms

France
New York University
Planned Parenthood Federation of America

Completed

Evaluating a Digital Health Information Tool (Chat/Text)

Behavior and Behavior Mechanisms

United States
New York University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents

Behavior and Behavior Mechanisms

United States
Johns Hopkins University

Active, not recruiting

Families Talking Together Plus: An Approach to Promote Sexual Delay and Strengthen Sexual Risk Avoidance Education (FTT+)

Behavior and Behavior Mechanisms

United States
University of Georgia
ZeaVision, LLC

Completed

The Effects of a Zeaxanthin Intervention on Visuomotor Function

Behavior and Behavior Mechanisms

United States
University of Michigan
Robert Wood Johnson Foundation

Completed

Impacts of Public Announcements of Goals and Outcomes on Goal Completion (Commit to Steps)

Behavior and Behavior Mechanisms

United States
Columbia University
National Institute of Mental Health (NIMH)

Completed

A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents

Behavior and Behavior Mechanisms

United States
Aarhus University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Recruiting

TDM for Optimized Outcome in Patients With mRCC.

Kidney Cancer | Renal Cell Carcinoma Metastatic | Drug Toxicity | Drug Side Effect | Drug Mechanism

Denmark
Mount St. Mary's College, Los Angeles, CA

Unknown

The Effects of Mid-thoracic Manipulation on Heart Rate Variability.

Neurophysiological Mechanisms Underlying Spinal Manipulation

United States
Agri Ibrahim Cecen University

Completed

Mindfulness-based Psychoeducation and Defense Mechanisms, Mindful Awareness

Mindfulness | Awareness | Psychoeducation | Defense Mechanisms

Turkey
Balance Therapeutics

Completed

A Study to Investigate the Mass Balance of BTD-001 (HV103)

Molecular Mechanisms of Pharmacological Action

United Kingdom
University of Florida
National Institute of Dental and Craniofacial Research (NIDCR)

Not yet recruiting

Dental-Child Interaction Training (DCIT)

Child Behavior | Behavior and Behavior Mechanisms
Swiss Federal Institute of Technology
Psychiatric University Hospital, Zurich; Eye Hospital Jules Gonin

Completed

Visuo-Tactile Integration and Body Ownership in the Human Brain

Behavior and Behavior Mechanisms | Body Representation

Switzerland
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Validation of a Making Decision Hybrid (Ecologic and Virtual) Task (LABLife)

Healthy Volunteers | Behavior and Behavior Mechanisms
University of Malaya
Ministry of Health, Malaysia

Unknown

Pharmacometabolomics of Andrographis Paniculata And Metformin In Healthy Volunteers Under Fasting Condition

Pharmacokinetics | Molecular Mechanisms of Pharmacological Action

Malaysia
University of Copenhagen
Carlsberg Foundation

Completed

Metabolic Imprints of Alcoholic Beverages (MetAl)

Metabolic Side Effects of Drugs and Substances

Denmark
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Deimplementing CXR After CVC (DRAUP) in the ICU

Implementation Science | Behavior and Behavior Mechanisms

United States
University Hospital, Basel, Switzerland

Completed

Acute Effects of the Two Alternative Sweeteners D-allulose and Erythritol on Metabolism

Physiological Satiation Mechanisms

Switzerland
Glostrup University Hospital, Copenhagen

Completed

Pupillary Response After Glaucoma Medication (pupil)

Drug Effect (Glaucoma Drugs)

Denmark
Luye Pharma Group Ltd.

Completed

Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Schizophrenia Spectrum and Other Psychotic Disorders | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Neurotransmitter Agents | Central...

United States
Fondation Lenval

Completed

Pharmacogenetics Anomaly Research in Children and Adolescents With Pharmacological Resistance to Psychotropic Drugs (M4P)

Psychotropic Drugs | Drug Resistance

France
Luye Pharma Group Ltd.

Completed

Relative Bioavailability of LY03010 Compared to Listed Drug

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Central Nervous System Depressants | Neurotransmitter Agents | Schizophrenia Spectrum

United States
Meir Medical Center

Unknown

The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies

High Risk Pregnancies | Telomere Length | Mechanisms of Telomter Homeostasis

Israel
Clinical Hospital Centre Zagreb
Croatian Science Foundation; University of Zagreb School of Medicine

Recruiting

Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Cardiovascular Drugs

Croatia
University of Iowa
Iowa Fraternal Order of Eagles

Completed

INcreasing Steps in PREgnancy Study (INSPiRE)

Pregnancy Related | Exercise | Sedentary Behavior | Behavior and Behavior Mechanisms

United States
University Hospital, Basel, Switzerland

Completed

Effect of Different Concentrations of Xylitol and Erythritol on Gut Peptide Release and Gastric Emptying in Humans

Physiological Satiation Mechanisms

Switzerland
The University of Tennessee, Knoxville

Withdrawn

Assessment of Thoughts and Feelings Occurring During and After a Meal

Feeding Behavior | Behavior | Food Habits | Behavior and Behavior Mechanisms

United States
University of Nevada, Las Vegas

Completed

Immediate Effects of Manipulation Versus Stretching on Upper Trapezius Pressure Pain Thresholds

Neurophysiological Mechanisms Manipulation

United States
Children's Hospital of Philadelphia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Peers for Promoting Adolescent Transplant Health (Peers4PATH)

Behavior and Behavior Mechanisms

United States
Medical University of Vienna

Completed

Head Elevation in Prone Position

Lung Mechanics | Gas Exchange

Austria

Clinical Trials on Drug Mechanism

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Norway

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Rare Diseases

Drug Interventions

Dietary Supplements

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