Clinical Trials on Drug-Drug Interaction (DDI)

Total 3063 results

Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Drug-Drug Interaction (DDI)

France
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Healthy Subjects | Pharmacokinetics | DDI (Drug-Drug Interaction)

Germany
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Hutchison Medipharma Limited

Completed

Fruquintinib Food Effect and Proton Pump Inhibitor Study

Food-drug Interaction | Drug Interaction

United States
University of Southern California

Recruiting

Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor

Drug Drug Interaction

United States
Daewoong Pharmaceutical Co. LTD.

Active, not recruiting

Phase 1 Clinical Trial to Evaluate the Effect of DWP14012 on the Pharmacokinetics of DWC202201 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Enrolling by invitation

Drug-drug Interactions Between DWC202211 and DWC202212 in Healthy Subjects (DWJ1610)

Drug-drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and DWC202202 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Italfarmaco

Completed

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Drug-Drug Interaction

Portugal
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Blade Therapeutics

Completed

Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Pharmacokinetic Interaction Between DWP14012 and DWC202005 in Healthy Volunteers

Drug-drug Interaction

Australia
Nanjing Yoko Biomedical Co., Ltd.

Completed

Drug-drug Interaction Study Between Edaravone and 2-Aminoethanesulfonic Acid in Compound Edaravone Injection

Drug-drug Interaction

China
Repros Therapeutics Inc.

Completed

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

Drug-drug Interaction

United States
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Drug Drug Interaction

United States, Sweden
Asceneuron S.A.

Not yet recruiting

Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy Subjects

Drug Drug Interaction

Netherlands
Daewoong Pharmaceutical Co. LTD.

Recruiting

Drug-drug Interactions Between DWC202313 and DWC202314 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Indiana University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-Drug Interaction

United States
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
CMP Development, LLC

Completed

Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)

Drug Drug Interaction

India
Pyramid Biosciences

Completed

A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers

Drug-drug Interaction

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Drug-drug Interaction Study of SPH3127

Drug Drug Interaction

China
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
University Hospital, Basel, Switzerland

Completed

Inhibition Metamizole 2020

Drug-drug Interaction

Switzerland
Genfit

Completed

Study to Investigate the Potential Drug-Drug Interaction Between Elafibranor and Indomethacin

Drug-drug Interaction

France
Santhera Pharmaceuticals

Completed

A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate

Drug-Drug Interaction

France
Sunnybrook Health Sciences Centre
University Health Network, Toronto

Completed

Effect of an Automated Paging System on Response to Critical Laboratory Values

Drug Drug Interactions | Critical Laboratory Values | Drug Laboratory Interactions

Canada
Guangdong Raynovent Biotech Co., Ltd

Completed

Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin

Drug Drug Interaction

China
Italfarmaco

Completed

The Potential of Givinostat as DDI Victim in Co-administration P-gp Inhibitor (Part 2)

Drug Drug Interaction

Portugal
Guangdong Raynovent Biotech Co., Ltd

Completed

Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid

Drug Drug Interaction

China
Italfarmaco

Completed

Givinostat and Metabolites Pharmacokinetics in Urine and Plasma (Part 3)

Drug Drug Interaction

Portugal
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and Aspirin in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Chong Kun Dang Pharmaceutical

Completed

CKD-506 Drug-Drug Interaction Study in Healthy Male Subjects

Drug Drug Interaction

Netherlands
HUYABIO International, LLC.

Completed

Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects

Drug-drug Interaction

United States, Australia
Haisco Pharmaceutical Group Co., Ltd.

Completed

Drug-drug Interaction Between Ciprofol and Mefanamic Acid or Valproate

Drug Drug Interaction

China
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy Subjects

Drug-drug Interaction

Australia
Guangdong Raynovent Biotech Co., Ltd

Completed

Study to Investigate the Potential Drug-Drug Interaction Between ZSP1273 and Oseltamivir

Drug-drug Interaction

China
University of California, San Francisco

Completed

Drug-Drug Interaction Between Rifampin and Fluvastatin

Drug-drug Interaction

United States
Hutchison Medipharma Limited
Covance

Completed

Fruquintinib CYP3A Inhibitor and Inducer Study

Drug Drug Interaction

United States
SymBio Pharmaceuticals

Completed

Drug-Drug Interaction Study of Intravenous Administration of SyB V-1901 and Cyclosporine in Japanese Healthy Subjects

Drug Drug Interaction

Japan
Biosplice Therapeutics, Inc.

Completed

Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers

Drug-Drug Interaction

United States
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib

Drug-drug Interaction

United States
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin

Drug-drug Interaction

United States
Lexicon Pharmaceuticals

Completed

A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects

Drug-drug Interaction

United States

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