Clinical Trials on Ebola Vaccines

Total 1087 results

Universitätsklinikum Hamburg-Eppendorf
Goethe University; German Federal Ministry of Education and Research; Bernhard... and other collaborators

Not yet recruiting

Immunity Induced by VSV-EBOV and Assessment of a Booster Dose in Individuals at Potential Occupational Risk for Exposure (PREPARE)

Ebola Vaccine

Germany
Inovio Pharmaceuticals
GeneOne Life Science, Inc.; Defense Advanced Research Projects Agency

Completed

Open-Label Study of INO-4212 With or Without INO-9012, Administered IM or ID Followed by Electroporation in Healthy Volunteers

Ebola Vaccine

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Prevenar® to Pneumo 23 in Reducing Carriage in Children

Vaccines, Pneumococcal | Vaccines, Pneumococcal Conjugate Vaccine
Makerere University
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda; Epicentre; Makerere University Lung Institute and other collaborators

Not yet recruiting

Solidarity/Tokomeza Ebola Trial (TOKOMEZA)

Sudan Ebola Virus Vaccines
Centre Hospitalier Universitaire Vaudois
GlaxoSmithKline; University of Lausanne; University of Lausanne Hospitals; World... and other collaborators

Completed

A Clinical Trial on the Candidate Vaccine cAd3-EBOZ in Healthy Adults in Switzerland

Ebola Vaccines

Switzerland
National Institute of Allergy and Infectious Diseases...

Completed

Experimental Vaccine for Prevention of Ebola Virus Infection

Ebola Virus Disease | Ebola Hemorrhagic Fever | Ebola Virus Vaccines | Envelope Glycoprotein, Ebola Virus | Filovirus

United States
Pfizer

Completed

Study to Evaluate 13 Valent Pneumococcal Conjugate Vaccine (13vPnC) Vaccine Followed by 23-valent Pneumococcal Polysaccharide Vaccine (23vPS) Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Vaccines, Pneumococcal Conjugate Vaccine

United States, Spain, France, Canada, Germany, Czechia, Sweden, Belgium, Poland, Netherlands
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects

Vaccines, Pneumococcal Conjugate Vaccine

South Africa
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects

Vaccines, Pneumococcal Conjugate Vaccine
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Prevenar Immunogenicity in High Risk Children

Vaccines, Pneumococcal Conjugate Vaccine
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Immunogenicity of Vaxelis™ in Children Previously Vaccinated With Vaxelis™ or Hexyon™ (V419-016)

Vaccines, Combined | Hexavalent Vaccine

Germany, Italy, Spain
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants in Brazil

Vaccines, Pneumococcal Conjugate Vaccine

Brazil
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Japanese Infants

Vaccines, Pneumococcal Conjugate Vaccine

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants

Vaccines, Pneumococcal Conjugate Vaccine

Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Post-Marketing Study of the Safety of Prevenar (Pneumococcal Conjugate Vaccine, 7-valent)

Vaccines, Pneumococcal Conjugate Vaccine

Philippines
Pfizer

Completed

A Phase 3 Trial Evaluating the Safety, Tolerability, and Immunogenicity of a 13-valent Pneumococcal Conjugate Vaccine in Japanese Elderly Adults Aged 65 Years Old and Older

Pneumococcal Vaccines | Pneumococcal Conjugate Vaccine

Japan
National Institute of Allergy and Infectious Diseases...

Completed

Ebola and Marburg Virus Vaccines

Ebola Virus Disease | Ebola Vaccines | Marburg Virus Disease | Marburgvirus | Ebolavirus

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating A 13-Valent Pneumococcal Conjugate Vaccine Administered to Infants in Taiwan

Vaccines | Pneumococcal Conjugate Vaccine

Taiwan
London School of Hygiene and Tropical Medicine
University of Sierra Leone; Janssen Vaccines & Prevention B.V.

Active, not recruiting

Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study

Infections | RNA Virus Infections | Virus Diseases | Mononegavirales Infections | Hemorrhagic Fevers, Viral | Hemorrhagic Fever, Ebola | Filoviridae Infections | Physiological Effects of Drugs | Vaccines | Ebola | Immunologic Factors

Sierra Leone
National Institute of Allergy and Infectious Diseases...

Completed

Partnership for Research on Ebola Vaccines in Liberia (PREVAIL)

Ebola Virus

Liberia
Institut National de la Santé Et de la Recherche...

Terminated

Tolerance and Activity Evaluation of High Doses of Favipiravir Against Ebola Virus in the Semen (FORCE)

Ebola Virus Survivor

Guinea
Merck Sharp & Dohme LLC
National Institute of Allergy and Infectious Diseases (NIAID); BioProtection...

Completed

Safety and Immunogenicity of Prime-Boost Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-002)

Ebola Viruses
National Institute of Allergy and Infectious Diseases...
US Military HIV Research Program

Completed

Ebola Sudan Chimpanzee Adenovirus Vector Vaccine in Healthy Adults

Ebola Virus

Uganda
University of Oxford
National Institute of Allergy and Infectious Diseases (NIAID); Wellcome Trust

Completed

A Study to Assess New Ebola Vaccines, cAd3-EBO Z and MVA-BN® Filo

Ebola | Ebola Zaire

United Kingdom
Merck Sharp & Dohme LLC
United States Department of Defense; BioProtection Systems Corporation

Completed

Vaccine Treatment for Ebola Virus in Healthy Adults (V920-001)

Ebola Virus
Dalhousie University
Canadian Institutes of Health Research (CIHR); NewLink Genetics Corporation

Completed

Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine (VSVΔG-ZEBOV)

Ebola Viruses
Centers for Disease Control and Prevention, China

Recruiting

Combined Immunization of COVID-19 Inactivated Vaccine With QIV and PPV23 (QIV;PPV23)

Pneumococcal Vaccines | Safety | Influenza Vaccines | COVID-19 Vaccines | Immunogenicity, Vaccine

China
Janssen Vaccines & Prevention B.V.
Institut National de la Santé Et de la Recherche Médicale, France; University...

Completed

A Study to Assess Safety, Tolerability, and Immunogenicity of Three Heterologus 2-dose Regimens of the Candidate Prophylactic Vaccines for Ebola in Healthy Adults

Ebola Viral Disease

France, United Kingdom
Merck Sharp & Dohme LLC

Completed

Evaluation of the Safety and Immunogenicity of Three Consistency Lots and a High-Dose Lot of rVSV-ZEBOV-GP (V920 Ebola Vaccine) in Healthy Adults (V920-012)

Prevention of Ebola Infection
Bandim Health Project

Active, not recruiting

OPV as Potential Protection Against COVID-19

Mortality | COVID | Morbidity | Poliovirus Vaccine, Oral | Non-Specific Effects of Vaccines

Guinea-Bissau
National Institute of Allergy and Infectious Diseases...

Completed

Investigational Therapeutics for the Treatment of People With Ebola Virus Disease

Ebola Virus

United States, Congo, The Democratic Republic of the
Merck Sharp & Dohme LLC
Department of Health and Human Services; BioProtection Systems Corporation

Completed

Placebo Controlled, Dose Response, Safety and Immunogenicity Study of Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-004)

Ebola Virus
Chimerix

Withdrawn

An Open-Label, Multicenter Study of the Safety and Anti Viral Activity of Brincidofovir (BCV, CMX001) for Ebola Virus Disease (CMX)

Ebola Virus
Jiangsu Province Centers for Disease Control and...
Beijing Institute of Biotechnology; Tianjin Cansino Biotechnology Inc

Completed

A Clinical Trial to Evaluate the Recombinant Human Type5 Adenovirus Vector Based Ebola Virus Disease Vaccine

Ebola Disease

Sierra Leone
Cerus Corporation

Terminated

A Prospective, Open Label, Phase 1 Safety Study of Passive Immune Therapy During Acute Ebola Virus Disease Using Transfusion of INTERCEPT Plasma Prepared From Volunteer Donors Who Have Recovered From Ebola Virus Disease

Acute Ebola Virus Disease

United States
London School of Hygiene and Tropical Medicine

Completed

Ad26.ZEBOV Booster in HIV+ Adults Previously Vaccinated With Ad26.ZEBOV/MVA-BN-Filo (EBOVAC HIV+ Booster Study)

Hiv | Ebola Virus Disease | Ebola

Kenya, Uganda
Janssen Vaccines & Prevention B.V.

Completed

A Study of 2-dose Vaccine Regimen Using 3 Consecutive Lots of Ad26.ZEBOV and MVA-BN-Filo in Adult Participants

Ebola

United States
University of Oxford

Active, not recruiting

A Study in Tanzania of a New Vaccine Against Two Types of Ebola

Ebola

Tanzania
National Institute of Allergy and Infectious Diseases...
Gilead Sciences

Completed

GS-5734 to Assess the Antiviral Activity, Longer-Term Clearance of Ebola Virus, and Safety in Male Ebola Survivors With Evidence of Ebola Virus Persistence in Semen

Ebola

Guinea, Liberia
Emergent BioSolutions
Centers for Disease Control and Prevention

Completed

VA-006 Vaccinia Vaccine (ACAM2000) for the Production of VIGIV

Smallpox Vaccine Adverse Reaction

United States
Bandim Health Project

Enrolling by invitation

Measles Vaccination at Health System Contacts

Mortality | Measles Vaccine | Hospital Admission | Non-specific (Heterologous) Effects of Vaccines

Guinea-Bissau
Novavax

Completed

Study to Evaluate the Immunogenicity and Safety of an Ebola Virus (EBOV) Glycoprotein (GP) Vaccine in Healthy Subjects

Ebola

Australia
University of Oxford

Completed

A Study of a New Vaccine Against Two Types of Ebola

Ebola

United Kingdom
MRC/UVRI and LSHTM Uganda Research Unit
Ministry of Health, Uganda

Recruiting

Addressing Medium- to Long-term EBOLA Associated Psychological Distress and Psychosocial Problems in Central Uganda (Ebola+D)

Ebola Virus Disease

Uganda
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Not yet recruiting

Pilot Study Evaluating the Impact of Delay Between Administration of Inmazeb Administration and Vaccination by Ervebo on Vaccine Immune Response on Healthy Volunteers

Ebola Virus Disease

Guinea
ANRS, Emerging Infectious Diseases

Not yet recruiting

Prophylaxis Vaccine Antibodies Ebola (PROVAE)

Ebola Virus Disease

Guinea
National Institute of Allergy and Infectious Diseases...
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Active, not recruiting

Partnership for Research on Ebola VACcinations (PREVAC)

Ebola Virus Disease

Guinea, Liberia, Mali, Sierra Leone
Janssen Vaccines & Prevention B.V.
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Completed

A Study of 2-dose Vaccination Regimen of Ad26.ZEBOV and MVA-BN-Filo in Infants

Ebola Virus Disease

Guinea, Sierra Leone
London School of Hygiene and Tropical Medicine
Institut National de la Santé Et de la Recherche Médicale, France; Universiteit... and other collaborators

Completed

EBOVAC-Salone Extension

Ebola Virus Disease

Sierra Leone
Universiteit Antwerpen
Johnson & Johnson; University of Kinshasa; Innovative Medicines Initiative; Coalition... and other collaborators

Completed

Study to Evaluate the Immunogenicity and Safety of a Heterologous Vaccine Regimen Against Ebola (EBOVAC3DRC)

Ebola Virus Disease

Congo, The Democratic Republic of the

Clinical Trials on Ebola Vaccines

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