Clinical Trials on Emphysema

Total 458 results

Spiration, Inc.
Tigermed Consulting Co., Ltd; Olympus Corporation

Completed

The Spiration Valve System for the Treatment of Severe Emphysema (REACH)

Pulmonary Disease, Chronic Obstructive | Empyhsema

China
Pulmonx Corporation

Recruiting

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema (CONVERT_II)

Emphysema or COPD | Emphysema, Pulmonary

Spain, Germany, Italy
Pulmonx Corporation

Active, not recruiting

Zephyr Etude Post-Inscription (French Registry)

Emphysema or COPD

France
Heidelberg University

Unknown

Endoscopic Lung Volume Reduction After Catheter-based CV Measurement in Patients With Heterogeneous Emphysema and Complete Interlobar Fissures

Heterogeneous Emphysema

Germany
Royal Brompton & Harefield NHS Foundation Trust

Completed

Use of Endobronchial Valves in Non-Upper Lobe Heterogeneous Emphysema

Heterogeneous Emphysema

United Kingdom
Aeris Therapeutics

Completed

Biologic Lung Volume Reduction (BLVR) Phase 2 Homogeneous Study

Homogeneous Emphysema

United States
Pulmonx Corporation

Completed

Safety and Feasibility Study of the Chartis System With Heterogeneous Emphysema Prior to Endobronchial Lung Volume Reduction (ELVR)

Heterogeneous Emphysema

Germany
University Medical Center Groningen

Completed

Chartis Collateral Ventilation Measurement: Conscious Sedation Versus General Anesthesia

Emphysema or COPD

Netherlands
Aeris Therapeutics

Completed

A Dose Ranging Study of the Aeris Polymeric Lung Volume Reduction (PLVR) System in Patients With Advanced Upper Lobe Predominant Emphysema

Advanced Emphysema

Germany
University Medical Center Groningen

Recruiting

Biological Investigation of Explanted Endobronchial Lung Valves Study (Bio-EXCEL)

Emphysema or COPD

Netherlands
Rabin Medical Center

Unknown

Emphysematous Lung Sealant Therapy in Homogeneous Emphysema

Patients With Advanced Homogeneous Emphysema

Israel
Aeris Therapeutics

Withdrawn

Phase 3 Study of the Biologic Lung Volume Reduction (BLVR) System in Advanced Upper Lobe Predominant (ULP) Emphysema

Advanced Upper Lobe Predominant Emphysema
Universität Duisburg-Essen

Recruiting

LVRS Versus BLVR in Patients With Homogenous Emphysema, CLUB-HE Trial

Emphysema or COPD

Germany
University Medical Center Groningen

Withdrawn

Introduction of the Vapor Treatment in The Netherlands (NEVEL)

Emphysema or COPD
Uptake Medical Technology, Inc.
MedPass International

Completed

A Pilot Study to Assess Treatment of Patients With Homogeneous Emphysema Using Sequential Segmental Bronchoscopic Thermal Vapor Ablation (NEXT STEP) (NEXT STEP)

Emphysema or COPD

Germany
Pulmonx Corporation

Completed

To Improve Lung Function and Symptoms for Emphysema Patients Using Zephyr Valves (TRANSFORM)

COPD | Heterogeneous Emphysema

Netherlands, Sweden, United Kingdom, Germany, France, Belgium
SurgiQuest, Inc.

Unknown

SurgiQuest AirSeal in Robotic Partial Nephrectomy - (TARPAN Study) (TARPAN)

Subcutaneous Emphysema

United States
Zoar Engelman

Recruiting

Airway Bypass - Safety and Feasibility Study (AIRWAY)

Emphysema or COPD

Georgia
Shanghai Chest Hospital

Not yet recruiting

A Multi-center RCT to Evaluate Subsegmental BTVA Treatment for Severe Emphysema (BTVA)

Severe Emphysema
Beijing Municipal Science & Technology Commission

Unknown

A Clinical Evaluation of Baofeikang Granule in Combined Pulmonary Fibrosis and Emphysema Treatment

Combined Pulmonary Fibrosis and Emphysema

China
Apreo Health, Inc.

Recruiting

Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema (BREATHE-2)

Emphysema or COPD

United Kingdom, Austria, Netherlands
Beth Israel Deaconess Medical Center

Recruiting

Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction (SAVED-1)

Emphysema or COPD

United States
Beth Israel Deaconess Medical Center
Pulmonx Corporation

Recruiting

Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema (COMPLETE-1)

Emphysema or COPD

United States
Uptake Medical Technology, Inc.

Recruiting

Post-Market BTVA Registry

Emphysema or COPD

Switzerland, Germany, Austria
Chelsea and Westminster NHS Foundation Trust

Unknown

Bronchoscopic Intrabullous Autologous Blood Instillation (BIABI) for Emphysema (BIABI)

Bullous Emphysema

United Kingdom
Pulmonx Corporation

Recruiting

Zephyr Valve Japan Post-Marketing Surveillance

Emphysema | COPD | Severe Emphysema

Japan
Apreo Health, Inc.

Recruiting

First in Human Study to Assess an Implant to Treat Severe Emphysema (BREATHE-1)

Emphysema or COPD

Australia
Pulmonx Corporation

Active, not recruiting

Fissure Closure With the AeriSeal System for CONVERTing Collateral Ventilation Status (CONVERT) (CONVERT)

Emphysema | COPD | Severe Emphysema

United Kingdom, France, Netherlands, Germany, Australia, Italy, Switzerland
University Medical Center Groningen

Completed

Evaluation of the Free Flow Medical Lung Tensioning Device System for the Treatment of Severe Emphysema (EFFORT)

Emphysema or COPD

Netherlands, Germany
University of Massachusetts, Worcester
UMass Memorial Health

Enrolling by invitation

Healthy at Home Pilot

COPD | COPD Exacerbation | Emphysema or COPD

United States
Asan Medical Center

Unknown

The Microbiome of Sputum, Urine and Feces in Healthy Persons and Chronic Obstructive Pulmonary Disease (COPD) Patients (COPD)

Pulmonary Disease, Chronic Obstructive | Microbiota | Emphysema or COPD

Korea, Republic of
Aarhus University Hospital

Recruiting

The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility

Chronic Obstructive Pulmonary Disease | Emphysema or COPD

Denmark
University Hospital, Basel, Switzerland

Recruiting

Comparison Between the Non-powered AEON™ Endostapler and Echelon FLEX™ Powered Plus Stapler With Regards to the Closure of Lung Tissue After Lung Resection in the Presence of Severe Lung Emphysema (Stapler)

Lung Resection | Postoperative Air Leak

Switzerland
Pulmonx International Sàrl

Completed

Improving Patient Outcomes by Selective Implantation of the Zephyr EBV - Study (IMPACT)

COPD Patients With Homogeneous Emphysema | Endoscopic Lung Volume Reduction With Endobronchial Valve

Germany, Austria, Netherlands
Rabin Medical Center

Unknown

The Value of Bronchoscopic Lung Volume Reduction by Endobronchial Valves in Patients With Single Lung Transplantation and Overinflation of the Native Lung

Native Lung Overinflation in Patients That Underwent Single Lung Transplantation Due to Emphysema

Israel
Heidelberg University

Terminated

Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency

Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)

Germany
Grifols Therapeutics LLC

Enrolling by invitation

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency (SPARTA-OLE)

Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency

United States, New Zealand, Denmark, Australia, Finland, Estonia, Canada, Poland, Russian Federation, Sweden, France
Alliance of Cardiothoracic and Vascular Surgeons

Terminated

Outpatient Chest Tube Management Following Thoracic Resection Improves Patient Length of Stay and Satisfaction Without Compromising Outcomes

Pneumothorax | Lung Cancer | Subcutaneous Emphysema

United States
Hospices Civils de Lyon

Unknown

Genetics of the Combined Pulmonary Fibrosis and Emphysema Syndrome (GENES-SEF)

Emphysema | Pulmonary Fibrosis | Healthy Subjects | Combined Pulmonary Fibrosis and Emphysema Syndrome

France
Grifols Therapeutics LLC

Active, not recruiting

Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD) (SPARTA)

Pulmonary Emphysema in Alpha-1 PI Deficiency

United States, Australia, Denmark, New Zealand, Estonia, Poland, Russian Federation, Sweden, Brazil, Canada, France, Finland
IHF GmbH - Institut für Herzinfarktforschung

Not yet recruiting

BENTO - Bronchoscopic Lung Volume Reduction in Severe Emphysema Using Thermoablation

Emphysema or Chronic Obstructive Pulmonary Disease

Germany
Boston Scientific Corporation
PneumRx, Inc.

Completed

Evaluation of the PneumRx Lung Volume Reduction Coil to Treat Emphysema

Emphysema

Germany, Netherlands
University Medical Center Groningen
Maastricht University Medical Center; Center of Expertise for Chronic Organ...

Completed

A Trial on the Effects of Bronchoscopic Lung Volume Reduction in Severe Emphysema. (SOLVE)

Emphysema

Netherlands
Boston Scientific Corporation
PneumRx, Inc.

Terminated

LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009) (CROSSOVER)

Emphysema

United States, Netherlands, France, Canada, United Kingdom
Lifetech Scientific (Shenzhen) Co., Ltd.

Active, not recruiting

Cinenses Lung Volume Reduction Reverser System First-in-man Study Treating Patients With Severe Emphysema

Emphysema

Germany
University Hospital, Toulouse

Terminated

Hyperinflation Assessment After Treatment by Lung Volume Reduction Coil (HEAT-LVRC)

Emphysema

France
Spiration, Inc.

Completed

REACH SVS Control Patient Cross-Over Study

Emphysema

China
Heidelberg University
Asklepios Kliniken Hamburg GmbH; Lung Clinic Hemer; Otto Wagner Hospital

Unknown

Spiration Valve System 9 mm European Post Market Evaluation Study

Emphysema

Germany
Hospital de Clinicas de Porto Alegre
Ministry of Health, Brazil; Conselho Nacional de Desenvolvimento Científico... and other collaborators

Completed

Safety Study of Bone-marrow Derived Mesenchymal Stromal Cells Associated With Endobronchial Valves in Emphysema

Pulmonary Emphysema

Brazil
CHU de Reims
PneumRx, Inc.

Unknown

Lung Volume Reduction Coil Treatment in Emphysema. (STICREVOLENS)

Emphysema

France

Clinical Trials on Emphysema

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