Clinical Trials on Eosinophilic Granulomatosis

Total 704 results

Medical University Innsbruck

Recruiting

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Characterizing Eosinophils (PROMETHEos)

Eosinophilic Asthma | Eosinophilic Pneumonia | EGPA - Eosinophilic Granulomatosis With Polyangiitis | Samter Triad | HES - Hypereosinophilic Syndrome

Austria
Assistance Publique - Hôpitaux de Paris
French Vasculitis Study Group

Completed

Rituximab in Eosinophilic Granulomatosis With Polyangiitis (REOVAS)

Eosinophilic Granulomatosis With Polyangiitis (EGPA)

France
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

A Study of Reslizumab in Patients 12 Years of Age and Older With Severe Eosinophilic Asthma

Eosinophils, Asthma

United States, Belgium, Canada, Czechia, France, Germany, Hungary, Israel, Poland, Romania, Russian Federation, Spain, Ukraine
Stanford University

Enrolling by invitation

Gastrointestinal STRING Test With Oral Immunotherapy (STRING)

Food Allergy | Eosinophilic Disorder

United States
Ann & Robert H Lurie Children's Hospital of Chicago

Recruiting

Eosinophilic Gastrointestinal Disorders Registry

Eosinophilic Gastroenteritis | Eosinophilic Esophagitis | Eosinophilic Colitis | Eosinophilic Gastrointestinal Disease

United States
AstraZeneca

Completed

Study to Characterise Patients Receiving Benralizumab in the Framework of an Individualized Access Program in Spain (ORBE)

Severe Eosinophilic Asthma

Spain
Medical University of Graz

Not yet recruiting

Clock Proteins as Prognostic Markers (CLOCK-PM)

Severe Eosinophilic Asthma
Imperial College London
AstraZeneca

Enrolling by invitation

Explore the Efficacy and Mechanism of Action of Tezepelumab in Eosinophilic Granulomatosis With Polyangiitis (RACEMATE)

EGPA - Eosinophilic Granulomatosis With Polyangiitis

United Kingdom
University Medical Center Groningen
GlaxoSmithKline

Recruiting

eGPA and Local Inflammation Within the Ear, Nose and Throat Area

EGPA - Eosinophilic Granulomatosis With Polyangiitis

Netherlands
McMaster University
St. Joseph's Healthcare Hamilton; AstraZeneca

Completed

Benralizumab in Patients With Inadequate Response to Anti-IL5 Monoclonal Antibody Therapies

Severe Prednisone Dependent Eosinophilic Asthma

Canada
Children's Hospital Medical Center, Cincinnati
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Recruiting

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages (OMEGA)

Eosinophilic Gastritis | Eosinophilic Gastroenteritis | Eosinophilic Esophagitis | Eosinophilic Colitis | Eosinophilic Gastrointestinal Disorders (EGIDs)

United States
Allakos Inc.

Completed

A Study to Assess AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis) (ENIGMA 2)

Eosinophilic Gastritis | Eosinophilic Duodenitis

United States
Children's Hospital Medical Center, Cincinnati
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Completed

Characteristics of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

Eosinophilic Gastritis | Eosinophilic Gastroenteritis | Eosinophilic Esophagitis | Eosinophilic Colitis

United States
Allakos Inc.

Completed

An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis

Eosinophilic Gastritis | Eosinophilic Gastroenteritis | Eosinophilic Duodenitis

United States
IRCCS Policlinico S. Matteo
Italian Society of Pediatric Allergy & Immunology - Pediatric Centers

Recruiting

National, Multicenter, Retrospective, Prospective Study to Evaluate Pediatric Gastrointestinal Eosinophilic Disorders (GOLDEN)

Eosinophilic Esophagitis | Eosinophilic Colitis | Eosinophilic Gastritis or Gastroenteritis | Eosinophilic Gastrointestinal Disorders

Italy
Arkansas Children's Hospital Research Institute

Withdrawn

Eosinophilic Gastrointestinal Disorders Patient Registry

Eosinophilic Gastritis | Eosinophilic Esophagitis | Eosinophilic Colitis | Eosinophilic Enteritis

United States
Mayo Clinic
GlaxoSmithKline

Withdrawn

Mepolizumab for Eosinophilic Fasciitis

Eosinophilic Fasciitis
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Unknown

Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-5 Humanized Monoclonal Antibody Injection

add-on Maintenance Treatment of Patients With Severe Eosinophilic Asthma

China
Regeneron Pharmaceuticals
Sanofi

Recruiting

A Trial to Learn if Dupilumab is Safe for and Helps Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis (ENGAGE)

Eosinophilic Gastritis | Eosinophilic Duodenitis | Eosinophilic Gastrointestinal Disease

United States, Poland, Italy, Japan, Australia
University of Pennsylvania
University of South Florida; University of Oxford

Completed

The ANCA Vasculitis Questionnaire (AAV-PRO©) (AAV-PRO)

Vasculitis | Churg-Strauss Syndrome (CSS) | Microscopic Polyangiitis (MPA) | Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA) | Granulomatosis With Polyangiitis (Wegener's) (GPA) | Wegener Granulomatosis (WG) | ANCA-Associated Vasculitis (AAV)

United States
Ahram Canadian University

Recruiting

High-Intensity Laser Therapy for Eosinophilic Fasciitis

Eosinophilic Fasciitis

Egypt
Children's Hospital Medical Center, Cincinnati
National Institutes of Health (NIH); Regeneron Pharmaceuticals

Active, not recruiting

Dupilumab in Eosinophilic Gastritis

Eosinophilic Gastritis | Eosinophilic Gastroenteritis

United States
AstraZeneca

Completed

Efficacy and Safety of Benralizumab in Patients With Eosinophilic Gastritis and/or Gastroenteritis (The HUDSON GI Study) (HUDSON GI)

Eosinophilic Gastritis | Eosinophilic Gastroenteritis

Italy, Spain, United States, Vietnam, Japan, Netherlands, Ukraine, Poland, Brazil
Allakos Inc.

Completed

A Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis (ENIGMA)

Eosinophilic Gastritis | Eosinophilic Gastroenteritis

United States
Allakos Inc.

Completed

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis (EoDyssey)

Eosinophilic Gastroenteritis | Eosinophilic Duodenitis

United States
Children's Hospital Medical Center, Cincinnati
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Completed

SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study (SOFEED)

Eosinophilic Esophagitis (EoE) | Eosinophilic Gastrointestinal Disorders (EGIDs)

United States
Federico II University

Recruiting

The Potential Role of Compounds Derived From Ultra-processed Foods in Pathogenesis of Eosinophilic Esophagitis

Esophagitis, Eosinophilic

Italy
National Institute of Allergy and Infectious Diseases...

Completed

Omalizumab to Treat Eosinophilic Gastroenteritis

Gastroenteritis

United States
GlaxoSmithKline

Completed

An Evaluation Of Mepolizumab In Therapy Of Eosinophilic Oesophagitis In Adult Patients

Oesophagitis, Eosinophilic

Switzerland
Children's Hospital Medical Center, Cincinnati
AstraZeneca

Completed

Benralizumab for Eosinophilic Gastritis (BEGS) (BEGS)

Eosinophilic Gastritis or Gastroenteritis

United States
Allakos Inc.

Withdrawn

A Study to Assess Subcutaneous AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (ENIGMA-SC)

Eosinophilic Gastritis | Eosinophilic Duodenitis

United States
Hamamatsu University

Completed

The Efficacy of Three Months-prednisolone Therapy for Chronic Eosinophilic Pneumonia

Chronic Disease | Eosinophilic Pneumonia

Japan
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)

Eosinophilic Oesophagitis

United States
GlaxoSmithKline

Completed

Intravenous Mepolizumab In Children With Eosinophilic Esophagitis

Oesophagitis, Eosinophilic

United States, Canada, United Kingdom, Australia
Medical University of Graz

Recruiting

Prostaglandin and Cannabinoid Receptors in EoE

Eosinophilic Esophagitis (EoE)

Austria
AQILION AB

Completed

SAD, MAD and Food Effect Evaluation of Safety, Tolerability, and PK of AQ280 in Healthy Subjects

Eosinophilic Esophagitis (EoE)

United Kingdom
Regeneron Pharmaceuticals
Sanofi

Active, not recruiting

Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE) (EoE KIDS)

Eosinophilic Esophagitis (EoE)

United States, Canada
Shire
Takeda Development Center Americas, Inc.

Terminated

Continuation Study With Budesonide Oral Suspension (BOS) for Adolescent and Adult Participants With Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis (EoE)

United States
Shire

Completed

OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension

Eosinophilic Esophagitis (EoE)

United States
Shire

Completed

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) (ORBIT2)

Eosinophilic Esophagitis (EoE)

United States
Children's Hospital Medical Center, Cincinnati
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Registry for Eosinophilic Gastrointestinal Disorders (REGID) (EoE)

Eosinophilic Esophagitis | Eosinophilic Gastrointestinal Disorders (EGID) | Eosinophilic Disorder

United States
AstraZeneca

Recruiting

A Real World Study to Capture Clinical and Patient Centered Outcomes in Adults With Severe Eosinophilic Asthma Treated With Benralizumab. (EMPOWAIR)

Severe Eosinophilic Asthma

Greece
AstraZeneca

Active, not recruiting

Patient Reported Outcomes in Adults With Severe Eosinophilic Asthma on Benralizumab. (POWER)

Severe Eosinophilic Asthma

Canada
University of Rostock

Unknown

Impact of Benralizumab Treatment on Circulating Dendritic Cells in Patients With Eosinophilic Asthma

Severe Eosinophilic Asthma

Germany
Allakos Inc.

Completed

An Extension Study of Lirentelimab in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)

Eosinophilic Gastritis | Eosinophilic Duodenitis

United States
Marc Rothenberg

Completed

Data Bank for Eosinophilic Disorders

Gastritis | Eosinophilic Gastroenteritis | Eosinophilic Esophagitis | Enteritis | Eosinophilic Colitis

United States
Areteia Therapeutics

Recruiting

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) (EXHALE-3)

Asthma | Eosinophilic Asthma | Asthma; Eosinophilic

United States, South Africa, United Kingdom, Korea, Republic of
Areteia Therapeutics

Recruiting

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma. (EXHALE-2)

Asthma | Eosinophilic Asthma | Asthma; Eosinophilic

United States, United Kingdom, Georgia, Romania, Brazil, Bulgaria, Korea, Republic of, Poland, Serbia, Argentina
AstraZeneca

Completed

Real World Study With Benralizumab in Severe Asthma in Switzerland (BEEPS)

Severe Eosinophilic Asthma

Switzerland
AstraZeneca

Completed

Real World Evidence of Benralizumab in Eosinophilic Severe AsThma in Russia (BEST)

Severe Eosinophilic Asthma

Russian Federation

Clinical Trials on Eosinophilic Granulomatosis

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