Clinical Trials on FMF

Total 90 results

University of Ulm

Active, not recruiting

Ruxolitinib and Pomalidomide Combination Therapy in Patients With Primary and Secondary MF (POMINC)

Primary Myelofibrosis | Secondary Myelofibrosis | Post-PV MF | PMF | SMF | Post-ET MF

Germany
Assiut University

Not yet recruiting

FMF and Atheroscelerosis

FMF
Tianjin Medical University Second Hospital

Recruiting

Pemigatinib for FGF/FGFR Alterations Advanced Pan Solid Tumors

Solid Tumor | FGF Receptor Gene Mutation | FGF Amplification | FGF Receptor Gene Family Rearrangement | FGF Receptor Gene Translocation

China
University of Nottingham

Completed

Effects of Five Days of Physical Inactivity on Endothelial Function in Healthy Humans

FMD

United Kingdom
Assaf Harofeh MC
Weizmann Institute of Science

Not yet recruiting

Assessing the Potential Role of the Gut Microbiome in Modulating Physical Abilities in Humans

FMT | Physical Abilities
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Arterial Remodeling in Smokers (TCA)

Smoking | FMD | IMT

Germany
Kartos Therapeutics, Inc.

Recruiting

KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment (BOREAS)

Primary Myelofibrosis (PMF) | Post-Polycythemia Vera MF (Post-PV-MF) | Post-Essential Thrombocythemia MF (Post-ET-MF)

United States, Korea, Republic of, Germany, Australia, Hungary, France, Spain, Italy, Taiwan, Thailand, Brazil, Poland, Turkey, Israel, Portugal, Romania, Argentina, Bulgaria, Canada, Croatia, Czechia, Lithuania, Mexico, Philippines, United... and more
Rejuven Dermaceutical Co., Ltd.

Completed

RJV001 Study in Adults Receiving Abdominoplasty

Submental Fat (SMF) | Double Chin

United States
Sheba Medical Center

Unknown

Colchicine Levels in the Serum of FMF (Familial Mediterranean Fever) Patients

FMF | Colchicine Resistance | Colchicine Toxicity

Israel
General and Teaching Hospital Celje

Completed

Novel Therapeutics and Endothelial Dysfunction in T1DM Patients (ENDIS)

Diabetes Mellitus, Type 1 | Biomarkers | Endothelial Dysfunction | Arterial Stiffness | FMD | Incretins | Endothelial Progenitor Cells | SGLT 2 Inhibitors | Glucose Excursions | FPF

Slovenia
Ajax Therapeutics, Inc.

Not yet recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | PMF | Post-Essential Thrombocythemia Myelofibrosis | PPV-MF | PET-MF

United States
Novartis Pharmaceuticals

Completed

Exploratory Phase II Study of INC424 Patients With Primary Myelofibrosis (PMF) or Post Polycythaemia Myelofibrosis (PPV MF) or Post Essential Thrombocythaemia Myelofibrosis (PET-MF) (MACS2030)

Primary Myelofibrosis (PMF) | Post Polycythaemia Myelofibrosis (PPV MF) | Post Essential Thrombocythaemia Myelofibrosis (PET-MF)

United Kingdom
Novartis Pharmaceuticals

Completed

A Phase I Study of Oral BGJ398 in Asian Patients

Tumor With Alterations of the FGF-R

China, Japan
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis

Primary Myelofibrosis (PMF) | Post-polycythemia Vera Myelofibrosis(Post-PV MF) | Post-essential Thrombocythemia Myelofibrosis(Post-ET MF)

China
Imago BioSciences, Inc., a subsidiary of Merck...

Completed

Bomedemstat (IMG-7289/MK-3543) in Participants With Myelofibrosis (IMG-7289-CTP-102/MK-3543-002)

Myelofibrosis | Primary Myelofibrosis (PMF) | Post-polycythemia Vera Myelofibrosis (PPV-MF) | Post-essential Thrombocythemia Myelofibrosis (PET-MF)

Germany, United States, Australia, Italy, United Kingdom
Taipei Veterans General Hospital, Taiwan
National Yang Ming University

Completed

Study Effect of Red Wine Consumption on Endothelial Progenitor Cells and Endothelial Function

Endothelial Progenitor Cells Numbers | Endothelial Function (FMD)

Taiwan
Icahn School of Medicine at Mount Sinai
Dompé Farmaceutici S.p.A

Recruiting

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

Myelofibrosis (PMF) | Post Essential Thrombocythemia Myelofibrosis (ET-MF) | Post Polycythemia Vera Related Myelofibrosis (PV-MF)

United States
Kartos Therapeutics, Inc.

Recruiting

Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis

Primary Myelofibrosis (PMF) | Post-Polycythemia Vera Myelofibrosis (Post-PV-MF) | Post-Essential Thrombocythemia Myelofibrosis (Post-ET-MF)

United States, Mexico, Bulgaria, Poland, Russian Federation, Belarus, Georgia, South Africa, Ukraine
Samus Therapeutics, Inc.

Terminated

Assess the Safety, Tolerability Oral PU-H71 in Subjects Taking Ruxolitinib

Primary Myelofibrosis (PMF) | Post-Polycythemia Vera Myelofibrosis (Post-PV MF) | Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF)

United States
GlaxoSmithKline

Active, not recruiting

Extended Access of Momelotinib in Adults With Myelofibrosis

Neoplasms | Primary Myelofibrosis (PMF) | Post-polycythemia Vera Myelofibrosis (Post-PV MF) | Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)

United States, Hungary, Israel, Spain, Taiwan, France, Australia, Germany, Belgium, Canada, Singapore, Korea, Republic of, United Kingdom, Denmark, Austria, Romania, Italy, Bulgaria, Poland, Netherlands
Mayo Clinic

Recruiting

The Feasibility and Acceptability of Utilizing Telehealth for Increasing Access to Bariatric Surgery

Telehealth | Face-2-Face (F2F)

United States
Sierra Oncology, Inc.

Completed

Efficacy of Momelotinib Versus Best Available Therapy in Anemic or Thrombocytopenic Subjects With Primary Myelofibrosis (MF), Post-polycythemia Vera MF, or Post-essential Thrombocythemia MF (Simplify 2)

Primary Myelofibrosis (PMF) | Post-essential Thrombocythemia Myelofibrosis (Post-ET MF) | Post-polycythemia Vera (Post-PV)

United States, Canada, France, Italy, Germany, Spain, Israel, United Kingdom
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Stool Transplant to Control Treatment-related Diarrhea

Fecal Microbiota Transplantation (FMT)

United States
Nutricia Research

Active, not recruiting

Renoir: A Randomised, Double-blind, Controlled Trial to Evaluate the Effects of a New Human Milk Fortifier on Growth and Tolerance in Preterm Infants. (Renoir)

Growth | Tolerance | Safety | Subjects in Need of a Human Milk Fortifier (HMF)

Netherlands, France, Germany, United Kingdom
University of Erlangen-Nürnberg Medical School

Completed

Influence of Nitric Oxide on Flow Mediated Dilation

FMD - Flow Mediated Dilation

Germany
Rambam Health Care Campus

Withdrawn

The Effect of Probiotics on Response to Therapy and on Adverse Effect in Patients Treated With Colchicine for Familial Mediterranean Fever.

Familial Mediterranean Fever (FMF )
Assistance Publique - Hôpitaux de Paris
Institut Imagine

Not yet recruiting

Are Mast Cells Involved in Autoinflammatory Diseases (INFLAMAST)

Autoinflammatory Disease | FMF | TRAPS | MKD | Cryopyrin Associated Periodic Syndrome | Haploinsufficiency

France
Szeged University

Unknown

Pulmonary Arterial Pressure Response During Exercise (PAPCOPDHS)

Healthy Subjects | COPD Patients | Semi-supine Echo (SSE) | Flow-mediated Vasodilatation (FMD) | High Sensitive C-reactive Protein (hsCRP)

Hungary
Halic University

Completed

Kinesiophobia in Familial Mediterranean Fever

FMF

Turkey
Assistance Publique - Hôpitaux de Paris

Unknown

Consequences of DNA Repair and Telomere Defects on the Function of the Immune System: Application to CVID and Immune Deficiencies With Dysmorphic Syndromes (IMMUNEREP)

Immune Deficiency and Early BMF in Childhood

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (KIN-ATTACK-FMF)

FMF

France
R-Pharm International, LLC
Atlant Clinical LLC; Center for Pharmaceutical Analytics LLC; Unimed Laboratories... and other collaborators

Recruiting

Safety and Efficacy of RPH-104 Used to Prevent Recurrent Fever Attacks in Adult Patients With Colchicine Resistant or Colchicine Intolerant Familial Mediterranean Fever

Familial Mediterranean Fever | FMF

Armenia, Georgia, Russian Federation
R-Pharm International, LLC
R-Pharm; Atlant Clinical LLC; Unimed Laboratories CJSC; Data Management 365; Center...

Recruiting

Efficacy and Safety of RPH-104 for Resolution and Prevention of Recurring Attacks in Adult Subjects With Familial Mediterranean Fever With Resistance to or Intolerance of Colchicine

Familial Mediterranean Fever | FMF

Armenia, Georgia, Russian Federation
Assaf Harofeh MC
Weizmann Institute of Science

Not yet recruiting

The Role of Microbiome in Recurrent Obesity

Obesity | Weight Loss | FMT
Istanbul University - Cerrahpasa (IUC)

Recruiting

The Effect of Video Game on Children With Familial Mediterranean Fever

FMF

Turkey
Ari M Grinspan

Terminated

Refined Fecal Microbiota Transplantation (FMT) for Ulcerative Colitis (UC) (REFOCUS)

Ulcerative Colitis | FMT | Fecal Microbiota Transplant

United States
University of Michigan
National Institute of Nursing Research (NINR)

Completed

Light Treatment to Improve Symptom Management of Fibromyalgia Syndrome

Fibromyalgia | FMS

United States
Astellas Pharma Global Development, Inc.

Completed

A Study of ASP2215 (Gilteritinib) Combined With Atezolizumab in Patients With Relapsed or Treatment Refractory FMS-like Tyrosine Kinase (FLT3) Mutated Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML) | Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation

United States
Novartis Pharmaceuticals

Available

Managed Access Programs for INC424, Ruxolitinib

Primary Myelofibrosis (PMF) | Polycythemia Vera (PV) | Post Polycythemia Myelofibrosis (PPV MF) | Thrombocythemia Myelofibrosis (PET-MF) | Severe/Very Severe COVID-19 Illness | Steroid Refractory Acute Graft Versus Host Disease (SR aGVHD) | Steroid Refractory Chronic Graft Versus Host Disease...
Astellas Pharma Inc

Active, not recruiting

A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FLT3 Mutation

Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation

China, Malaysia, Russian Federation, Singapore, Thailand
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Role of Oxygen for Vascular Dysfunction

Endothelial Dysfunction | Oxygen Saturation | Microcirculation | FMD | IMT | Oxygen Pressure | Carbon Dioxide Pressure | Forced Expiratory Volume After 1 Second

Germany
Novartis Pharmaceuticals

Completed

Asian Phase II Study of INC424 in Patients With Primary Myelofibrosis (MF), Post-PV MF or Post-ET MF

Primary Myelofibrosis (MF) | Post-Polycythemia Vera (PV) MF | Post-Essential Thrombocythemia (ET) MF

Taiwan, Japan, Korea, Republic of, China
University of Palermo

Completed

Gluten-related Disorders in Familial Mediterranean Fever Patients

Familial Mediterranean Fever (FMF) | Not-celiac Wheat Sensitivity (NCWS)

Italy
National Human Genome Research Institute (NHGRI)
Merck Sharp & Dohme LLC; Duke University; University of Massachusetts, Worcester

Recruiting

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

Fever | Genetic Diseases | Familial Mediterranean Fever (FMF) | Autoinflammation | Periodic Fever | ROSAH | ALPK1

United States
Astellas Pharma Korea, Inc.

Recruiting

A Study to Assess the Safety of Xospata in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-Like Tyrosine Kinase 3 (FLT3) Mutation

Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation

Korea, Republic of
University of Aarhus

Completed

Faecal Microbiota Transplantation for Patients With Diabetes Mellitus Type 1 and Severe Gastrointestinal Neuropathy (Fadigas)

Diabetes Mellitus, Type 1 | Faecal Microbiota Transplantation (FMT) | Gastrointestinal Neuropathy

Denmark
Finch Research and Development LLC.

Withdrawn

Efficacy, Safety, and Tolerability Study of Oral Full-Spectrum MicrobiotaTM (CP101) in Subjects With Autism Spectrum Disorder and Associated GI Symptoms (SPROUT) (SPROUT)

Autism Spectrum Disorder | Autism | ASD | FMT | Fecal Transplant | Autistic Thinking | Autistic Behavior | Fecal Microbiota Transplant | Finch | CP101 | SPROUT
Astellas Pharma Global Development, Inc.

Completed

A Study of ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Therapy for Subjects With FMS-like Tyrosine Kinase 3 (FLT3/ITD) Acute Myeloid Leukemia (AML) in First Complete Remission

Acute Myeloid Leukemia (AML) | Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) / Internal Tandem Duplication (ITD) Mutation

Taiwan, Poland, Serbia, United States, Brazil, Canada, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Portugal, Romania, Spain, Sweden, United Kingdom
Astellas Pharma Global Development, Inc.

No longer available

Early Access Program (EAP) of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or With FLT3-Mutated AML in Complete Remission (CR) With Minimal Residual Disease (MRD)

Acute Myeloid Leukemia (AML) | FMS-like Tyrosine Kinase-3 (FLT3) Mutations

Australia, Italy, United Kingdom
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Synbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis (SYNCH)

Probiotics | Non-Alcoholic Fatty Liver Disease | Microbiome | Gut Microbiome | Fecal Microbiota Transplantation | Intestinal Microbiome | FMT | Non Alcoholic Steatohepatitis | Prebiotics

Netherlands

Clinical Trials on FMF

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CROs in Slovakia

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