Clinical Trials on Focal Seizures

Total 2180 results

SK Life Science, Inc.

Active, not recruiting

Randomized, Double-blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in POS

Partial Seizure | Focal Seizure

China, Japan, Korea, Republic of
Byteflies
Thomas Jefferson University

Recruiting

EpiCare@Home Validation Study for Focal Onset Seizures

Epilepsy | Seizures | Seizures, Focal | Seizure, Refractory

United States
Beth Israel Deaconess Medical Center
AbbVie

Recruiting

BOTOX Effects on Seizure Severity and Susceptibility

Drug-resistant Focal Seizure

United States
Neuroelectrics Corporation

Recruiting

Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy

Epilepsy | Seizures | Refractory Epilepsy | Epilepsy, Tonic-Clonic | Epilepsy in Children | Seizures, Focal | Focal Seizure

Spain, United States, France, Belgium
Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
Aziende Chimiche Riunite Angelini Francesco S.p.A
Hippocrates Research

Completed

This is a Retrospective Study on the Use of CENOBAMATE as Adjunctive Treatment in Patients Suffering From Epilepsy in Early Access Program in Germany, France and UK (CENOR)

Epilepsy | Focal Onset Seizure

United Kingdom, France, Germany
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Unknown

A Real World Study on the Efficacy and Safety of Lacosamide as Add-on Therapy for Focal-onset Epilepsy

Epilepsy | Focal-Onset Seizure

China
SK Life Science, Inc.

Completed

A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures.

Epilepsy | Epilepsy, Complex Partial | Seizure Disorder | Complex Partial Seizures | Epilepsy, Focal
SK Life Science, Inc.

Completed

A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures.

Epilepsy | Epilepsy, Complex Partial | Seizure Disorder | Complex Partial Seizures | Epilepsy, Focal
Biogen

Completed

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy (OPUS)

Epilepsy, Focal Seizures, Partial Seizures

United States
Aziende Chimiche Riunite Angelini Francesco S.p.A
Iqvia Pty Ltd

Recruiting

Cenobamate in Adults With Focal-Onset Seizures (BLESS)

Epilepsy | Neurological Disorder | Focal-Onset Seizure

Italy
Reliev Technologies

Not yet recruiting

Seizures Detection in Real Life Setting (ECEME)

Focal Epilepsy | Epilepsy; Seizure
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Focal Onset Seizures

United States, Spain, Italy, Croatia, Portugal, Poland, Chile, Argentina, Austria, Czechia
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE2)

Focal Onset Seizures

United States, Spain, Australia, Poland, Canada, Bulgaria, Italy, United Kingdom
All India Institute of Medical Sciences, Bhubaneswar

Completed

Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures

Seizures, Focal

India
Supernus Pharmaceuticals, Inc.

Active, not recruiting

BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures (FIAS)

Focal Impaired Awareness Seizures

Australia
Rapport Therapeutics Inc.

Not yet recruiting

Study Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With Refractory Focal Epilepsy

Focal Onset Seizures
Janssen Research & Development, LLC

Completed

A Study to Investigate JNJ-40411813 in Combination With Levetiracetam or Brivaracetam in Epilepsy

Focal Onset Seizures

Germany, Korea, Republic of, Belgium, United States, Russian Federation, Poland, Ukraine, Spain
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part A

Epilepsy | Focal Seizures

United Kingdom, Spain, Czechia
Equilibre Biopharmaceuticals B.V.

Terminated

Study of EQU-001 for Uncontrolled Focal Onset Seizures

Focal Onset Seizures

United States, Israel
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part B

Epilepsy | Focal Seizures

Italy, Poland, United Kingdom, Spain, Hungary, Czechia
NeuroPace

Recruiting

RNS System RESPONSE Study (RESPONSE)

Epilepsy | Drug Resistant Epilepsy | Focal Epilepsy | Partial Seizure | Neurostimulator; Complications

United States
El Instituto Nacional de Neurologia y Neurocirugia...

Completed

TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure Disorder

Psychogenic Non-Epileptic Seizure

Mexico
King's College London
King's College Hospital NHS Trust

Completed

Subcutaneous EEG: Forecasting of Epileptic Seizures (SUBER)

Epilepsies, Focal

United Kingdom
Brain Sentinel

Unknown

An Exploratory Trial Using sEMG to Differentiate PNES From Epileptic Seizures

Epilepsy | Non-Epileptic Seizure | Motor Seizure

Austria
Wei Zhao
The Affiliated Hospital of Qingdao University; Qianfoshan Hospital; The Second...

Recruiting

Antiepileptic Drugs in Elderly Patients

Seizure, Epileptic

China
Overseas Pharmaceuticals, Ltd.
GX pharma technology (beijing) Co., Ltd

Active, not recruiting

An Open Label, Balanced, Randomized, 3×3 Latin Square Design Comparing of Brivaracetam Sustained-release Tablets and Brivaracetam Tablets in the Oral Comparative Pharmacokinetic(PK) Study in Chinese Healthy Adult Subjects Under Fasting Conditions.

Partial Seizure

China
Dartmouth-Hitchcock Medical Center

Completed

Project UPLIFT for Psychogenic Non-Epileptic Seizures (PNES)

Depression | Non-Epileptic Seizure | Psychogenic Non-Epileptic Seizure | Psychogenic Seizure

United States
Boston Children's Hospital

Recruiting

Genetics of Epilepsy and Related Disorders

Epilepsy | Dravet Syndrome | Infantile Spasms | Epileptic Encephalopathy | Ohtahara Syndrome | Early Myoclonic Epileptic Encephalopathy | PCDH19-related Epilepsy and Related Conditions | KCNQ2-Related Epileptic Encephalopathy | Epilepsy of Infancy With Migrating Focal Seizures (Disorder)

United States
Central Hospital, Nancy, France
Dr Coraline HINGRAY; Pr Raymund SCHWAN; Dr Vincent LAPREVOTE; Dr Jean Pierre VIGNAL and other collaborators

Unknown

Evaluation of a Telephone Follow-up Procedure on the Quality of Life in Psychogenic Non-epileptic Seizures (EDUQ-CPNE)

Psychogenic Non Epileptic Seizure

France
Abbott

Terminated

A Study of the Safety and Efficacy of Depakote Sprinkle Capsules in the Treatment of Partial Seizures in Children

Partial Seizure Disorder

United States
Cerebral Therapeutics LLC

Terminated

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

Refractory Epilepsy

Israel, Australia
Michael A. Gelfand, MD, PhD
Epilepsy Foundation

Completed

Novel Helmet Design in Patients With Seizures

Generalized Tonic Clonic Seizure | Drug Resistant Epilepsy | Drop Seizures | Complex Partial Seizure | Fall Due to Seizure

United States
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Enrolling by invitation

An Open-label Study of XEN1101 in Epilepsy (X-TOLE4)

Focal Epilepsy | Tonic-Clonic Seizures

Spain, United States, Canada, Poland
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures

Epilepsy | Epilepsies, Partial | Partial Seizure Disorder | Complex Partial Seizure Disorder

Costa Rica, Peru, El Salvador, Guatemala
Overwatch Digital Health
Bracane Company

Unknown

Study to Validate Novel Seizure-Detection Algorithm

Epilepsy | Seizures | Seizure Disorder | Epileptic Seizures | Seizures, Motor | Epileptic

United States
State Budgetary Healthcare Institution, National...

Enrolling by invitation

Thermocoagulation in Drug Resistant Focal Epilepsy

Epilepsy | Epilepsies, Partial | Epilepsy Intractable | Seizures, Focal

Russian Federation
Chinese University of Hong Kong

Unknown

Post-market Study of AMPA Receptor Antagonists for Epilepsy Patients in Hong Kong

Generalized Epilepsy | Focal Epilepsy | Partial Seizures, Simple

Hong Kong
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
İpek Dokurel

Active, not recruiting

Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy? (levcbz)

Epilepsy; Syndrome, Seizures of Localized Onset

Turkey
Children's Hospital of Fudan University

Recruiting

Etiology and Treatment of Neonatal Seizure

Seizures | Seizure Disorder | Seizure Newborn | Seizure Generalized

China
Hôpital Armand Trousseau
Hopital Universitaire Robert-Debre; Centre Hospitalier Intercommunal Creteil; Versailles Hospital and other collaborators

Completed

Nervous System Infections Among Patients With Febrile Seizure

Encephalitis | Meningitis | Seizure | Febrile Seizure

France
Assistance Publique - Hôpitaux de Paris

Terminated

Perampanel in Focal Status Epilepticus (PEPSI)

Epilepticus; Status, Focal Motor

France
UCB Pharma GmbH

Completed

Study Evaluating Changes in Total Drug Load and Seizure Frequency Using Vimpat® (Lacosamide) in Combination Therapy (VICTOS)

Focal Epilepsy With and Without Secondary Generalization

Germany, Austria
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Sandoz Inc. and UCB Pharma, Inc (Keppra) 750 mg Levetiracetam Tablets In Healthy Adults Volunteers Under Fasting Conditions

Seizure
Taipei Medical University WanFang Hospital

Completed

Utility of Laboratory Testing for Children With Seizure in Emergency Department

Seizure

Taiwan
AstraZeneca

Completed

Acid Suppressing Drug Seizure Epidemiology Study

Seizure

Spain

Clinical Trials on Focal Seizures

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