Clinical Trials on Genetic Sucrase-Isomaltase Deficiency

Total 1476 results

QOL Medical, LLC

Recruiting

7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels

Congenital Sucrase-Isomaltase Deficiency | CSID | Sucrase Isomaltase Deficiency

United States
Steno Diabetes Center Copenhagen
The Novo Nordisk Foundation Center for Basic Metabolic Research; Department... and other collaborators

Completed

The Effect on Metabolism, Food Intake and Preferences of a Knockout Gene Variant Involved in Carbohydrate Metabolism

Diabetes Mellitus, Type 2 | Metabolic Disease | Sucrase Isomaltase Deficiency | Sucrose Intolerance Congenital

Greenland
Lovisenberg Diakonale Hospital
University of Bergen

Not yet recruiting

Sucrase-isomaltase Deficiency as a Cause of Irritable Bowel Syndrome

Irritable Bowel Syndrome | Functional Gastrointestinal Disorders | Sucrase Isomaltase Deficiency | Sucrose Intolerance Due to Sucrase-Isomaltase Deficiency | Carbohydrate; Malabsorption
QOL Medical, LLC

Completed

Adult Pilot Study for Reference Ranges and Optimal Cut-offs for the Sucrose Challenge Test and Sucrose Breath Test

Congenital Sucrase-Isomaltase Deficiency

United States
QOL Medical, LLC

Withdrawn

A Trial to Evaluate the Frequency of Genetic Sucrase-Isomaltase Deficiency Genotypes, and the Efficacy and Safety of Sucraid® (Sacrosidase) Oral Solution in Subjects With Chronic Diarrhea and Sucrase Deficiency (GSID-E)

Genetic Sucrase-Isomaltase Deficiency
QOL Medical, LLC
Johns Hopkins University; Massachusetts General Hospital; Baylor College of Medicine and other collaborators

Completed

Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Prevalence Study (GPS) (CSID GPS)

Congenital Sucrase-isomaltase Deficiency (CSID)

United States
Nottingham University Hospitals NHS Trust
CICbioGUNE; Christian-Albrechts-University of Kiel; University of Veterinary...

Not yet recruiting

Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity (GenMalCarb)

Irritable Bowel Syndrome (IBS) | Sucrase Isomaltase Deficiency
Region Skane

Enrolling by invitation

The Effect of Sugar Load in IBS Patients Depending on Sucrase-isomaltase Genes

Irritable Bowel Syndrome | Sucrase-Isomaltase Deficiency

Sweden
National Institute of Allergy and Infectious Diseases...

Recruiting

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

Primary Immune Deficiency

United States, Turkey
University Hospital, Caen

Completed

Pediatric Intensive Care Unit and Primary Immune Deficiency (PICUPID)

Immuno-Deficiency

France
Eli Lilly and Company

Completed

Observational Study of Somatropin Treatment in Children (GeNeSIS)

Growth Hormone (GH) Deficiency | Short Stature Homeobox Containing Gene (SHOX) Deficiency | SHOX Deficiency-related Disorder | Non-GH-deficient Growth Disorders
Stanford University
Grace Science Foundation

Terminated

NGLY1 Deficiency: A Prospective Natural History Study

Genetic Syndrome

United States
CSL Behring

Completed

Study of Immune Deficiency Patients Treated With Subcutaneous Immunoglobulin (IgPro20, Hizentra®) on Weekly and Biweekly Schedules

Primary Immune Deficiency | Secondary Immune Deficiency

Canada
CSL Behring

Completed

Study of Subcutaneous Immunoglobulin in Patients With PID Requiring IgG Replacement Therapy

Primary Immune Deficiency

United States
University Hospital, Caen

Completed

Intensive Care Unit and Secondary and Primary Immune Deficiency (ICUSPID)

Primary Immune Deficiency Disorder

France
CSL Limited

Completed

Ig NextGen 10% in Patients With Primary Immune Deficiency (PID)

Primary Immune Deficiency (PID)

Australia
Hopital Foch
Siemens Healthcare QT

Recruiting

A Prospective Monocentric Study to Assess the Concordance of Lung MRI Compared to Chest CT Scan to Assess the Extent and Severity of Bronchial and Parenchymal Pulmonary Lesions in Adult Patients With Primary Immune Deficiency (PID) . (IRMvsSCANNER)

Primary Immune Deficiency

France
Green Cross Corporation
Atlantic Research Group

Recruiting

Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency

Primary Immune Deficiency

United States
CSL Behring

Completed

Retrospective Chart Review of Subcutaneous IgG Use in Infants

Primary Immune Deficiency

United States
Caja Costarricense de Seguro Social

Completed

Primary Immunodeficiencies in Costa Rican Adults

Primary Immune Deficiency in Adults

Costa Rica
Therapure Biopharma Inc

Unknown

Study of PlasmaCap IG in Adults and Children With PIDD

Primary Immune Deficiency Diseases (PIDD)

United States, Canada
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)

Primary Immune Deficiency

Japan
CSL Behring

Completed

Extension Study of Subcutaneous Immunoglobulin Human in Patients With Primary Immunodeficiency (PID)

Primary Immune Deficiency

United States
CSL Limited

Completed

Safety Study of Subcutaneous Ig NextGen 16% in Patients With Primary Immunodeficiency

Primary Immune Deficiency

Australia, New Zealand
Assistance Publique - Hôpitaux de Paris

Recruiting

Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE) (ARTEGENE)

Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency

France
University of Zurich

Recruiting

Identification of New Inborn Errors of Immunity

Primary Immune Deficiency Disorder

Switzerland
Octapharma

Completed

Study to Monitor Subcutaneous Human Immunoglobulin Administered at Modified Dosing Regimens in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

United States
Octapharma

Completed

Study of Octanorm Subcutaneous IG in Patients With PID

Primary Immune Deficiency Disorder

United States, Canada, Czechia, Hungary, Poland, Russian Federation, Slovakia
University of South Florida

Unknown

Evaluate Bacteriophage as a Useful Immunogen in Patients With Primary Immune Deficiency Diseases (PIDD) (Bacteriophage)

Primary Immune Deficiency Diseases

United States
Assistance Publique - Hôpitaux de Paris

Completed

Primitive Immunodeficiency and Pregnancy (PREPI)

Primary Immune Deficiency

France
University of Zurich

Recruiting

Pathophysiology of Inborn Immunodeficiencies

Primary Immune Deficiency Disorder

Switzerland
National Institute of Allergy and Infectious Diseases...

Terminated

Antibody Production in Immune Disorders

Primary Immune Deficiency

United States
Green Cross Corporation

Withdrawn

Study of Immune Globulin Intravenous (Human) GC5101F in Subjects With Primary Humoral Immunodeficiency

Primary Immune Deficiency Disorder
Kuwait Society for Allergy and Clinical Immunology

Completed

Primary Immunodeficiency in Kuwait

Primary Immune Deficiency Disorder

Kuwait
Karolinska University Hospital

Completed

Study of Vitamin D3 Substitution to Patients With Primary Immunodeficiency (VITAPID)

Primary Immune Deficiency Disorder

Sweden
Octapharma

Completed

Octagam 5% Versus Comparator Post Marketing Trial

Primary Immune Deficiency Disorder

United States
Baylor College of Medicine
Children's National Research Institute

Recruiting

Hepatic Histopathology in Urea Cycle Disorders

Ornithine Transcarbamylase Deficiency | Urea Cycle Disorder | Carbamyl Phosphate Synthetase Deficiency | Argininosuccinic Aciduria | Hyperargininemia | Citrullinemia 1 | ARGI Deficiency | ASL Deficiency | ASS Deficiency | NAGS Deficiency

United States
Octapharma

Completed

Study to Evaluate the Efficacy, Tolerability and Safety of Octanorm in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

Russian Federation
CSL Behring

Completed

Follow-up Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)

Primary Immune Deficiency Disorder

Japan
ADMA Biologics, Inc.

Completed

Open Label, Phase III Study of NABI-IGIV 10% [Immune Globulin Intravenous(Human), 10%] In Subjects With Primary Immune Deficiency Disorders (PIDD)

Primary Immune Deficiency Disorders (PIDD)

United States
The First Hospital of Jilin University
National Natural Science Foundation of China

Unknown

Study on the Mechanism of Neurodevelopment Dysplasia of Fetal Brain Caused by ASNS Gene Mutation

Genetic Diseases, Inborn | Asparagine Synthetase Deficiency

China
ADMA Biologics, Inc.

Completed

Study to Evaluate Safety and Pharmacokinetics of BIVIGAM® in Primary Immune Deficiency Subjects Aged 2 to 16

Humoral Immune Response

United States
Instituto Grifols, S.A.

Completed

Safety and Efficacy Study of Flebogamma 5% DIF IGIV in Pediatric Subjects

Primary Immune Deficiency Disease

United States
ADMA Biologics, Inc.

Completed

Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)

Primary Immune Deficiency Disorder

United States
Eunice Kennedy Shriver National Institute of Child...
Children's National Research Institute

Terminated

Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease
GWT-TUD GmbH

Completed

Facilitated Immunoglobulin Administration Registry and Outcomes Study (FIGARO) (FIGARO)

Primary Immunodeficiency | Secondary Immune Deficiency

Germany, Italy, France
Instituto de Desarrollo e Investigaciones Pediátricas...

Unknown

Iron Deficiency Anemia, Iron Supplementation and Genomic Stability in Infants

Iron-deficiency | Anemia

Argentina
Federal Research Institute of Pediatric Hematology...

Completed

TCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PID

Primary Immune Deficiency Disorder | Hematopoietic Stem Cell Transplantation

Russian Federation
University of Alberta
Octapharma

Recruiting

Observational Study of Subcutaneous Immunoglobulin (Cutaquig) in Patients With Primary and Secondary Immunodeficiency.

Primary Immune Deficiency Disorder | Secondary Immune Deficiency

Canada
University of Pennsylvania

Terminated

Phase I Study of Adenoviral Vector Mediated Gene Transfer for Ornithine Transcarbamylase in Adults With Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease

Clinical Trials on Genetic Sucrase-Isomaltase Deficiency

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