Clinical Trials on Genotype

Total 166 results

University of Southern Denmark
Odense University Hospital

Terminated

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Cytochrome P450 Phenotype and Genotype Metrics

Denmark
Chinese Academy of Sciences
LanZhou University

Completed

Cytochrome P450 2C19 Variant is Related to Pharmacokinetics of Glipizide Extended Release Tablet in Chinese Subjects

Pharmacokinetic | Genotype

China
Biohaven Pharmaceuticals, Inc.

Active, not recruiting

Trial in Adult Subjects With Spinocerebellar Ataxia

Spinocerebellar Ataxias | Spinocerebellar Ataxia Genotype Type 1 | Spinocerebellar Ataxia Genotype Type 2 | Spinocerebellar Ataxia Genotype Type 3 | Spinocerebellar Ataxia Genotype Type 6 | Spinocerebellar Ataxia Genotype Type 7 | Spinocerebellar Ataxia Genotype Type 8 | Spinocerebellar Ataxia Genotype...

United States
Matthias Schwab

Completed

Open Label Study for the Functional Characterization of Drug Metabolism and Transport (IKP243)

Genotype-related Drug Metabolism

Germany
Samsung Medical Center

Unknown

Isoniazid Dosage Prediction Model Development

NAT2 Genotype

Korea, Republic of
Bristol-Myers Squibb

Completed

Study of the Safety & PK of INX-08189 in Chronically-infected HCV, Treatment-naïve Subjects

HCV (Genotype 1)

United States, Puerto Rico
Sequenom, Inc.
NAFTNet

Completed

A Noninvasive Test for Fetal RHD Genotype (NAFTnet RHD)

Rhesus D Genotype

United States, Canada
Sequenom, Inc.
Sequenom Center for Molecular Medicine

Completed

Evaluation of a Noninvasive Fetal RHD Genotyping Test (IRIS)

Rhesus D Genotype

United States
Bispebjerg Hospital
University of Copenhagen; Duke University; The Ministry of Science, Technology... and other collaborators

Completed

Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype

Carboxylesterase 1 (CES1) Genotype | CES1 Activity

Denmark
California Pacific Medical Center Research Institute
Children's Mercy Hospital Kansas City

Withdrawn

The Impact of Genetic Variation in CYP2D6 on the Pharmacokinetics and Pharmacodynamics of Methamphetamine

Methamphetamine Metabolism, CYP2D6 Genotype

United States
National Research Council, Spain
IMDEA Food; CEIP (primary school) Jara Carrillo (Alcantarilla, Murcia, Spain); IES (secondary school) Alcántara (Alcantarilla, Murcia, Spain)

Completed

Genotype, Metabotype and Diet in a Cohort of Children and Adolescents From the Southeast of Spain. (PolyMicroBio)

Genotype, Metabotype and Dietary Habits

Spain
Inje University

Completed

STUDY The Effect of HNF-4A G60D Variant on the In VIVO CYP2D6 Activity By Tolterodine Pharmacokinetic Study (HNF4a)

Healthy Subjects | Genotype Guided(HNF4a)
University of Southern Denmark

Completed

Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and Clopidogrel

CYP2C19 Genotypes

Denmark
National Taiwan University Hospital

Not yet recruiting

UGT1A1 Genotyping in Taiwanese Cancer Patients

The Influence of the UGT1A1 Genotype
Bispebjerg Hospital
University of Copenhagen; Duke University; The Ministry of Science, Technology... and other collaborators

Completed

Impact of CES1 Genotype on Metabolism of Methylphenidate

Carboxylesterase 1 (CES1) Genotype | CES1 Activity

Denmark
Northwell Health

Terminated

1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain

High Risk MC4R Genotype | Low Risk MC4R Genotype | One Week or Less Antipsychotic Lifetime Exposure

United States
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Evaluate Pharmacokinetics and Safety of Slow Release DHEA (DHEA)

Asthma | Genotype

United States
Krishnadevaraya College of Dental Sciences & Hospital

Not yet recruiting

Comparison of Microneedling and CTG for Gingival Augmentation- A RCT

Gingival Phenotype
Hacettepe University

Completed

Can Modified Coronally Advanced Tunnel be an Alternative in Gingival Phenotype Modification?

Gingival Phenotype

Turkey
Central Hospital, Nancy, France

Recruiting

FAMILY INHERITANCE, GENE-GENE AND GENE-ENVIRONMENT INTERACTIONS IN THE FIELD OF CARDIOVASCULAR AND RENAL DISEASES. Fifth Visit of the STANISLAS Cohort

Cardiovascular Diseases | Risk Factors | Nutrition | Cohort Studies | Genotype

France
London School of Hygiene and Tropical Medicine
University of Ulster

Terminated

Pilot Evaluation of the Effect of Riboflavin Supplementation on Blood Pressure and Possible Effect Modification by the MTHFR C677T Genotype (RiboBP)

High Blood Pressure | MTHFR C677T Genotype

Gambia
National Eye Institute (NEI)

Recruiting

Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene

Retinal Disease | Genotype

United States
Gilead Sciences

Completed

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 4 or 5 HCV Infection

Chronic Genotype 4 HCV | Chronic Genotype 5 HCV

France
Korea University Anam Hospital
National Cancer Center, Korea; Korean Breast Cancer Study Group

Unknown

CYP2D6 Genotype on the Clinical Effect of Tamoxifen (ASTRRA-CYP2D6)

Breast Neoplasms | Genotype | Tamoxifen | CYP2D6

Korea, Republic of
Children's Mercy Hospital Kansas City
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Biomarkers of CYP2D6 and CYP3A4 Variability in Pediatrics

Drug Metabolism Phenotype

United States
Herlev Hospital

Completed

Study of the Correlation Between Specific Genes and Cognitive Dysfunction After Surgery

Cognitive Impairment | Genotype

Denmark
Misr International University

Recruiting

Assessment of Gingival Thickness Using Colored Periodontal Probe

Gingival Phenotype

Egypt
Seoul National University Hospital

Completed

Clinical Trial to Evaluate the Influence of Genotype on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Influence of Genotype of Drug Metabolizing Enzyme or Transporter on the Pharmacokinetics/Pharmacodynamics of Clopidogrel | Influence of Aspirin on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Korea, Republic of
Peking University

Recruiting

Targeted Treatment Plus Tislelizumab and HAIC for Advanced CRCLM Failed From Standard Systemic Treatment

Liver Metastasis Colon Cancer | MSS | ctDNA Genotype | Failed From Standard Treatment

China
National Institute of Mental Health (NIMH)

Completed

Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers

fMRI | Brain Disease | Brain Mapping | Genotype | Allelic Frequencies of Genetic Markers

United States
The University of Hong Kong
The Hong Kong Polytechnic University; Griffith University

Completed

Physical Exercise Training to Enhance Executive and Social Functions

Broad Autism Phenotype

Hong Kong
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.

Completed

A Phase III Study to Evaluate Efficacy and Safety of TG-2349 in Combination With DAG181 and RBV for HCV Type I Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
Peking University People's Hospital

Completed

To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
University of Alabama at Birmingham
National Institutes of Health (NIH); Mereo BioPharma

Completed

Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency (ATALANTa)

Emphysema or COPD | Alpha-1 Antitrypsin Deficiency (AATD) | Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I Mutations

United States
Eunice Kennedy Shriver National Institute of Child...

Not yet recruiting

Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnancy: A Deep Phenotype Study

Cardiovascular Phenotype | Metabolic Phenotype | Hypertensive Disease | Psychological Phenotype | Audio

United States
Universitas Padjadjaran

Completed

Disorders of Sex Development (DSD) 46.XY in Three Siblings

Genotype

Indonesia
ANRS, Emerging Infectious Diseases
Bristol-Myers Squibb

Completed

Therapy With Asunaprevir, Daclatasvir, Ribavirin and Pegylated Interferon Alpha-2a in HCV Genotype 4-infected Patients Who Have Failed to a Previous Therapy With Peg-Interferon/Ribavirin (ANRS HC32 QUATTRO)

Hepatitis C Virus Genotype 4 Infection

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

Recurrent Mixed Phenotype Acute Leukemia | Acute Leukemia of Ambiguous Lineage | Acute Undifferentiated Leukemia | Acute Bilineal Leukemia | Acute Biphenotypic Leukemia | Mixed Phenotype Acute Leukemia | Mixed Phenotype Acute Leukemia, B/Myeloid, Not Otherwise Specified | Mixed Phenotype Acute Leukemia...

United States
ANRS, Emerging Infectious Diseases
Bristol-Myers Squibb

Withdrawn

Pilot Study to Assess Efficacy and Safety of a Triple Therapy With Asunaprevir, Daclatasvir, and BMS-791325 in HCV Genotype 4-infected Patients After Failure of Pegylated Interferon-Ribavirin Regimen (QUATTROTURBO)

Hepatitis C Virus Genotype 4 Infection

France
University of Ulster
DSM Nutritional Products, Inc.

Unknown

RIBOGENE: Optimisation of Riboflavin Status in Hypertensive Adults With a Genetic Predisposition to Elevated Blood Pressure (RIBOGENE)

Participants With the MTHFR 677TT Genotype

United Kingdom
University of Maryland, Baltimore

Active, not recruiting

Blinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPAL

Mixed Phenotype Acute Leukemia (MPAL) | Measurable Residual Disease (MRD)

United States
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1b Study of PPI-461 in Patients With HCV Genotype 1

Chronic Genotype 1 Hepatitis C Virus Infection

United Kingdom, Denmark, United States
Memorial Sloan Kettering Cancer Center
Tel-Aviv Sourasky Medical Center; Sheba Medical Center; Princess Alexandra Hospital...

Active, not recruiting

Risk Stratification Among Individuals Who Have Many Moles on Their Skin

High-Risk Nevus Phenotype

United States
Aga Khan University

Completed

Interferon-gamma With Interferon Alpha and Ribavirin for Hepatitis C Non-responders

Hepatitis C | Genotype 3 | Non-responders | Relapsers

Pakistan
National Cancer Institute (NCI)

Active, not recruiting

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Recurrent Mixed Phenotype Acute Leukemia | Refractory Mixed Phenotype Acute Leukemia

United States
University of Nebraska

Completed

Determine the Efficacy and Safety of Harvoni in Genotype 1 Chronic Hepatitis c Infected People Who Are Alcoholics

Genotype 1 Hepatitis C Virus

United States
Idera Pharmaceuticals, Inc.

Completed

Study of Combination Treatment With IMO-2125 and Ribavirin in Naïve Hepatitis C-infected, Genotype 1 Patients

Hepatitis C, Treatment Naïve, Genotype 1 Patients

France
Yassin Abdelghaffar Charity Center for Liver Disease...
Society of Friends of Liver Patients in the Arab World (SLPAW); Egyptian Cure...

Completed

Treatment of Egyptian Hepatitis C Genotype 4 Infected Children (and Adolescents) With Combined Sofosbuvir & Daclatasvir

Hepatitis C Genotype 4

Egypt
Bristol-Myers Squibb

Completed

Safety and Efficacy Study of Daclatasvir (BMS-790052) Plus Pegylated Interferon-Alfa 2a and Ribavirin in Patients Coinfected With Untreated Hepatitis C Virus and HIV Virus

Hepatitis C, Genotype 1

United States, Australia, France, Germany, Spain, Canada, Puerto Rico, Argentina, Brazil, Russian Federation, United Kingdom, Italy, Belgium
Beijing Anzhen Hospital

Recruiting

Genotyping GUided Antiplatelet theRapy in pAtieNts Treated With Drug Eluting stEnts (GUARANTEE)

Angina, Stable | Acute Coronary Syndrome | Drug-Eluting Stents | Genotype

China

Clinical Trials on Genotype

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gabon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations