Clinical Trials on Growth Hormone Deficiency With Pituitary Anomalies

Total 307 results

AEterna Zentaris

Completed

Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency

Growth Hormone Deficiency With Pituitary Anomalies

United Kingdom, United States, France, Poland, Spain, Austria, Germany, Italy, Serbia
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Slovakia
Eli Lilly and Company

Completed

A Prospective Observational Study of Effect of Somatropin on Growth Hormone Deficient Adults (HypoCCS)

Hypopituitarism | Pituitary Insufficiency | Growth Hormone Deficiency, Adult
Rabin Medical Center

Recruiting

Effect of Nutritional Formula Supplementation on Growth Rate of Growth Hormone (GH) Treated Children With Growth Hormone Deficiency (GHD) After the Second Year of Therapy

Growth Retardation | IGHD - Isolated Growth Hormone Deficiency

Israel
Novo Nordisk A/S

Completed

First Human Dose Trial of NNC0195-0092 (Somapacitan) in Healthy Subjects

Healthy | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
The Cleveland Clinic
Massachusetts General Hospital; Oregon Health and Science University; Allegheny...

Completed

The Glucagon Stimulation Test for Evaluation of Adult Growth Hormone Deficiency and Adrenocorticotropic Axis (GST)

Adult Growth Hormone Deficiency | Hypothalamic-pituitary Disorders

United States
Novo Nordisk A/S

Recruiting

Investigating Efficacy and Safety of Once-weekly NNC0195-0092 (Somapacitan) Treatment Compared to Daily Growth Hormone Treatment (Norditropin® FlexPro®) in Growth Hormone Treatment naïve Pre-pubertal Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children

United States, India, Japan, Israel, Austria, Belgium, Brazil, France, Slovenia, Sweden, Turkey, Germany, Ukraine
Novo Nordisk A/S

Completed

A Trial Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Dose of Long-acting Growth Hormone (Somapacitan) Compared to Daily Dosing of Norditropin® SimpleXx® in Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children

France, Israel, Austria, Spain, Switzerland, North Macedonia, Norway, Slovenia, Belgium, Sweden
Novo Nordisk A/S

Completed

Trial to Compare the Efficacy and Safety of NNC0195-0092 (Somapacitan) With Placebo and Norditropin® FlexPro® (Somatropin) in Adults With Growth Hormone Deficiency. (REAL 1)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

United States, Poland, India, Japan, Russian Federation, United Kingdom, Germany, Sweden, Israel, Malaysia, Turkey, South Africa, Australia, Latvia, Lithuania, Romania, Brazil, Norway, Ukraine
Novo Nordisk A/S

Completed

French National Registry of Adults With Growth Hormone Deficiency Treated With Somatropin

Growth Hormone Disorder | Adult Growth Hormone Deficiency

France
Novo Nordisk A/S

Completed

A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily Norditropin NordiFlex® in Adults With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Denmark, Sweden
Novo Nordisk A/S

Completed

A Trial to Evaluate the Safety of Once Weekly Dosing of Somapacitan (NNC0195-0092) and Daily Norditropin® FlexPro® for 52 Weeks in Previously Human Growth Hormone Treated Japanese Adults With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Long-term Trial on Growth Hormone Deficiency in Adults (GHDA)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Growth Hormone Deficiency in Adults (GHDA)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone Deficiency (REAL 2)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Denmark, France, Germany, Japan, Sweden, United Kingdom
Novo Nordisk A/S

Completed

Safety and Efficacy of Somatropin in Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children

United States
Novo Nordisk A/S

Completed

Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Sweden, Austria, Spain, Switzerland, Germany, France, Australia, Poland, United Kingdom, Norway, Belgium, Hungary
Novo Nordisk A/S

Completed

Assessing the Minimal Important Difference (MID) of the Treatment Related Impact Measure-Adult Growth Hormone Deficiency (TRIM-AGHD)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

United States
LG Life Sciences
BioPartners GmbH

Completed

Treatment of Adults With Growth Hormone Deficiency

Adult Growth Hormone Deficiency | Pituitary Disorders

United States
Ascendis Pharma Endocrinology Division A/S

Completed

A Phase 3 Trial of the Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)

Endocrine System Diseases | Pituitary Diseases | Hormones | Growth Hormone Deficiency, Pediatric | hGH (Human Growth Hormone)

United States, Armenia, Australia, Belarus, Bulgaria, Georgia, Greece, Italy, New Zealand, Poland, Romania, Russian Federation, Turkey, Ukraine
LG Life Sciences
BioPartners GmbH

Completed

Treatment of Adults With Growth Hormone Deficiency

Adult Growth Hormone Deficiency | Pituitary Disorders
Novo Nordisk A/S

Completed

Validation of Two Measures for Growth Hormone Deficiency in Children, the Treatment Related Impact Measure of Childhood Growth Hormone Deficiency (TRIM-CGHD) and the Treatment Burden Measure of Childhood Growth Hormone Deficiency (TB-CGHD)

Growth Hormone Deficiency in Children | Growth Disorder

United States, United Kingdom
Novo Nordisk A/S

Terminated

Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Greece
EMD Serono

Completed

Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency

Pituitary Dwarfism | Childhood-onset Growth Hormone Deficiency

United States
Versartis Inc.

Terminated

Versartis Trial in Pre-pubertal Japanese Children With Growth Hormone Deficiency (GHD) to Assess Long-Acting Growth Hormone (Somavaratan, VRS-317)

Growth Disorders | Pediatric Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Various Degrees of Impaired Renal Function Compared to Subjects With Normal Renal Function

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
Novo Nordisk A/S

Completed

Effect of Growth Hormone in Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Growth Disorder | Idiopathic Short Stature

United States
Novo Nordisk A/S

Completed

Liquid Somatropin Formulation in Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children

Turkey
Novo Nordisk A/S

Completed

Long-term Trial on Growth Hormone Deficiency in Adults (GHDA)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Novo Nordisk A/S

Completed

Observational Study of the Safety and Efficacy of Norditropin® in Adult Patients With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Japan
Pfizer

Withdrawn

A Study to Compare the Experiences of Taking Daily Growth Hormone Injections to Weekly Ngenla in Children With Low Levels of Growth Hormone

Pediatric Growth Hormone Deficiency
Ascendis Pharma Endocrinology Division A/S

Active, not recruiting

A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency

Endocrine System Diseases | Adult Growth Hormone Deficiency | Hormone Deficiency

United States, Armenia, Georgia, Greece, Ukraine, Australia, Canada, France, Israel, Italy, Japan, Malaysia, Poland, Romania, Serbia, Slovakia, Spain, Turkey, United Kingdom, Germany, Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

Safety and Efficacy Study of Recombinant Human Growth Hormone in Adult Growth Hormone Deficiency Patients (HM10560A)

Adult Growth Hormone Deficiency

Hungary
EMD Serono

Terminated

Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study

Growth Hormone Deficiency (GHD)

United States
National Institute of Diabetes and Digestive and...
Genentech, Inc.

Completed

Consequence of Lifetime Isolated Growth Hormone Deficiency

Growth Hormone Deficiency

Brazil
Novo Nordisk A/S

Enrolling by invitation

A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information

Adult Growth Hormone Deficiency

United States, Saudi Arabia, Germany, Slovenia
Cinnagen

Completed

Comparing Efficacy and Safety of CinnaGen Biosimilar Growth Hormone (CinnaTropin®) Versus Nordilet in Children With Idiopathic Growth Hormone Deficiency

Idiopathic Growth Hormone Deficiency
Versartis Inc.

Completed

Versartis Trial in Children to Assess Long-Acting Growth Hormone (VERTICAL)

Pediatric Growth Hormone Deficiency

United States
Versartis Inc.
Premier Research Group plc

Completed

Versartis International Trial in Adults With Long-Acting Growth Hormone (VITAL)

Adult Growth Hormone Deficiency

United States, Australia, Germany, United Kingdom
Pfizer

Terminated

Efficacy of Somatropin in Adult Patients With Isolated Growth Hormone Deficiency (IGHD)

Growth Hormone Deficiency

Germany
Eli Lilly and Company

Completed

Extension Study on Safety of Long-Term Growth Hormone Replacement in Adult Patients With Growth Hormone Deficiency

Adult Growth Hormone Deficiency

Japan
TJ Biopharma Co., Ltd.

Completed

A Study to Evaluating the Efficacy and Safety of Recombinant Long-acting Human Growth Hormone (TJ101) in Children With Growth Hormone Deficiency

Pediatric Growth Hormone Deficiency

China
OPKO Health, Inc.

Terminated

A Phase 3, Multicenter Study To Evaluate The Efficacy And Safety Of MOD-4023 In Adults With Growth Hormone Deficiency

Adult Growth Hormone Deficiency

Israel
Merck KGaA, Darmstadt, Germany

Completed

An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)

Adult Growth Hormone Deficiency

United Kingdom, Germany, Australia, Sweden
Ascendis Pharma A/S

Completed

A Safety, Pharmacokinetic and Pharmacodynamic Study of ACP-001 (TransCon hGH) in Adults With Growth Hormone Deficiency

Adult Growth Hormone Deficiency

Sweden, Denmark, Germany, Italy
Ascendis Pharma A/S

Completed

Safety, PK/PD (Pharmacokinetics/Pharmacodynamics) and Efficacy of ACP-001 Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)

Growth Hormone Deficiency (GHD)

Egypt, Turkey, Germany, Poland, France, Hungary, Russian Federation, Ukraine, Belarus, Bulgaria, Czech Republic, Greece, Romania, Slovenia
Versartis Inc.
Premier Research Group plc

Terminated

Open-label Extension Study to Evaluate the Safety of Long-term Twice-monthly Administration of Somavaratan in Adult Growth Hormone Deficiency (AGHD)

Adult Growth Hormone Deficiency (AGHD)
Ascendis Pharma Endocrinology Division A/S

Completed

A Safety, Tolerability and Efficacy Study of TransCon hGH in Children With Growth Hormone Deficiency

Endocrine System Diseases | Pituitary Diseases | Hormone Deficiency | Growth Hormone Deficiency, Pediatric

United States, Canada, Australia, New Zealand
Odense University Hospital

Unknown

Bone Structure in Patients With Adult Onset Growth Hormone Deficiency Assessed Using High Resolution Peripheral Quantitative Computed Tomography

Adult Onset Growth Hormone Deficiency

Denmark
Ascendis Pharma A/S

Completed

A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial (enliGHten)

Endocrine System Diseases | Pituitary Diseases | Hormone Deficiency | Growth Hormone Deficiency, Pediatric

United States, Armenia, Belarus, Bulgaria, Georgia, Greece, Russian Federation, Ukraine, Australia, New Zealand, Poland

Clinical Trials on Growth Hormone Deficiency With Pituitary Anomalies

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