Clinical Trials on Growth Hormone Insensitivity Syndrome (GHIS)

Total 2984 results

Insmed Incorporated

Completed

IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Laron Syndrome

Laron Syndrome | Growth Hormone Insensitivity Syndrome (GHIS)

United States, Argentina, Australia, Brazil, China, Egypt, Germany, Israel, Italy, Norway, Peru, Slovakia, Turkey, United Kingdom
Ipsen
University of Oklahoma

Completed

Long-Term Treatment With rhIGF-1 in GHIS

Growth Hormone Insensitivity Syndrome

United States
Oregon Health and Science University

Completed

Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates

Growth Hormone Deficiency

United States
Novo Nordisk A/S

Completed

A Single Dose Trial in Growth Hormone Deficient Children Investigating Safety, Pharmacokinetics and Pharmacodynamics of Long Acting Growth Hormone

Growth Hormone Disorder | Growth Hormone Deficiency in Children

Israel, Denmark, Belgium, Spain, Macedonia, The Former Yugoslav Republic of, Turkey, United Kingdom, France, Slovenia, Czech Republic
Novo Nordisk A/S

Withdrawn

An Observational Study on Treatment Compliance by Children Treated With Growth Hormone (IMPACT)

Growth Hormone Disorder | Growth Hormone Deficiency in Children
Novo Nordisk A/S

Completed

Effect of Somatropin on Left Ventricular Mass in Growth Hormone Deficient Adult Patients

Growth Hormone Disorder | Adult Growth Hormone Deficiency

France
Novo Nordisk A/S

Completed

Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Denmark
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Adults (NordiWIN)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Germany
Novo Nordisk A/S

Completed

A Single Dose Trial in Healthy Caucasians and Japanese Subjects Investigating the Pharmacokinetics of Somatropin

Healthy | Growth Hormone Disorder | Adult Growth Hormone Deficiency

United States
Novo Nordisk A/S

Completed

An Observational Study Validating a Score That Quantifies the Therapeutic Response to Treatment With Norditropin® (GET)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Germany
Novo Nordisk A/S

Completed

Observational Study of Norditropin NordiFlex® With NordiFlex PenMate™

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Delivery Systems

Germany, Netherlands, Sweden
Teva Pharmaceutical Industries, Ltd.

Terminated

A Phase 2, Safety and Dose-Finding Study in Treatment-Naive, Pre-Pubertal, Growth Hormone-Deficient Children

Growth Hormone-Deficiency

Belarus, Bulgaria, Georgia, Greece, Hungary, Israel, Poland, Romania, Russian Federation, Serbia, Spain, Turkey, Ukraine
University of Aarhus
Aarhus University Hospital

Unknown

Effects of Growth Hormone and IGF-1 on Anabolic Signals and Stem Cell Recruitment in Human Skeletal Muscle

Growth Hormone Deficiency | Growth Hormone Treatment

Denmark
Ipsen

Completed

A Post Marketing Surveillance Study for NutropinAq® in Adults With Growth Hormone Deficiency

Growth Hormone Disorders

United Kingdom
OPKO Health, Inc.

Completed

Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Pediatric Growth Hormone Deficiency

Greece, Hungary, Slovakia
OPKO Health, Inc.

Completed

Long Term Follow up Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Growth Hormone Deficiency (GHD)

United States, Belarus, Greece, Hungary, Russian Federation, Ukraine
Altus Pharmaceuticals

Completed

Study of an Extended-Release, Crystalline Formulation of Recombinant Human Growth Hormone (ALTU-238) in Growth Hormone Deficient Adults to Determine Pharmacokinetics, Pharmacodynamics, and Drug Safety

Adult Growth Hormone Deficiency

United States
OPKO Health, Inc.

Completed

MOD-4023 (Long-Lasting Human Growth Hormone (hGH)) Study in Growth Hormone Deficient Adults (GHDA)

Adult Growth Hormone Deficiency

Czechia, Hungary, Israel, Serbia, Slovakia, Slovenia
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Trail to Compare Pharmacokinetics of Two PEG-rhGH Injections With Different Preparations

Pediatric Growth Hormone Deficiency (PGHD)

China
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Bioequivalence Study of Two Different PEG-rhGH Preparations.

Pediatric Growth Hormone Deficiency (PGHD)

China
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Trial to Compare Pharmacokinetics of Two Different PEG-rhGH Preparations

Pediatric Growth Hormone Deficiency (PGHD)

China
Novo Nordisk A/S

Completed

Validation of a Questionnaire That Identifies the Reasons for Non-adherence to Existing Growth Hormone Therapy

Growth Hormone Deficiency in Children

Germany
Pfizer

Recruiting

Ngenla Subcutaneous Injection Special Investigation

Growth Hormone Deficiency Without Epiphyseal Closure

Japan
GeneScience Pharmaceuticals Co., Ltd.

Unknown

Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children

Growth Retardation

China
AEterna Zentaris

Completed

Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test.

Diagnosis of Adult Growth Hormone Deficiency (AGDH)

United States
Northwell Health

Recruiting

Randomized Clinical Trial of Two Different Initial Growth Hormone Doses in Children

Growth | Growth Disorders | Growth Failure | Growth Hormone Treatment

United States
Pfizer

Not yet recruiting

Korean Post-marketing Surveillance Ngenla® Pre-filled Pen Injection for the Treatment of Pediatric Patients With Growth Disturbance Due to Insufficient Secretion of Growth Hormone

Pediatric Growth Hormone Deficiency
LG Life Sciences
BioPartners GmbH

Unknown

Treatment of Children With Insufficient Secretion of Growth Hormone (BPLG-004)

Growth Hormone Deficiency (GHD)

United States
University of Palermo

Completed

Three-times-weekly Versus Daily Growth Hormone (GH) Treatment in naïve GH-deficient Children (GH 3 wk dose)

Growth Hormone Treatment

Italy
Prof. Eli Hershkovitz

Unknown

Detection of Difficulties and Improvement Compliance to Growth Hormone Treatment

Growth Hormone Treatment
University of Aarhus
Bispebjerg Hospital

Completed

The Effect of Local Injectet GH on the Collagen Synthesis in the Ligamentum Patella

Elderly | Growth Hormone

Denmark
Merck KGaA, Darmstadt, Germany

Completed

Metabolic Endocrinology and Growth Hormone in Adults (MEGHA FRANCE)

Adult Growth Hormone Deficiency
University of Minnesota

Recruiting

Assessment of Adherence, Quality of Life, Clinical Response and Safety of Daily and Long-Acting Growth Hormone Therapy (LAuGH TRACK)

Growth Hormone Deficiency | Growth Hormone Treatment

United States
Pennington Biomedical Research Center

Completed

Single Low-Dose of Supplement Amino Acid

Growth Hormone | Amino Acid

United States
Novo Nordisk A/S

Completed

Dose Study in Healthy Males Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083 Compared to Norditropin® SimpleXx®

Healthy | Growth Hormone Disorder

Denmark
Imperial College London
Novo Nordisk A/S

Completed

The Effect of Growth Hormone Replacement on Liver Fat

Fatty Liver | Growth Hormone, Recombinant

United Kingdom
University Hospital Birmingham

Recruiting

The Effects of Growth Hormone Treatment Discontinuation in Adults on Metabolic Profile, Body Composition and Quality Of Life (GAMBOL Study) (GAMBOL)

Adult Growth Hormone Deficiency

United Kingdom
Novo Nordisk A/S

Completed

Dose Study in Healthy Japanese Males Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083

Healthy | Growth Hormone Disorder

Germany
Ascendis Pharma Endocrinology Division A/S

Completed

A Phase 3 Trial of the Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)

Endocrine System Diseases | Pituitary Diseases | Hormones | Growth Hormone Deficiency, Pediatric | hGH (Human Growth Hormone)

United States, Armenia, Australia, Belarus, Bulgaria, Georgia, Greece, Italy, New Zealand, Poland, Romania, Russian Federation, Turkey, Ukraine
Versartis Inc.

Completed

Long-Acting Growth Hormone in Children Compared to Daily rhGH (VELOCITY)

Growth Disorders
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Children (GrowthWIN II)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age | Growth Disorder | Idiopathic Short Stature

Germany
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Slovakia
Lactalis
Biosearch S.A.

Completed

Tolerance of Infants With Cow's Milk Protein Allergy to Extensively Hydrolyzed Rice Protein or Casein Infant Formulas (JUNGLO)

Growth Failure | Tolerance | Cow Milk Protein Sensitivity

Spain
EMD Serono

Completed

r-hGH Liquid Multidose Versus Freeze-dried Multidose Bioequivalence Trial

Growth Hormone Deficiency | Growth Failure

Germany
Rabin Medical Center

Recruiting

Effect of Nutritional Formula Supplementation on Growth Rate of Growth Hormone (GH) Treated Children With Growth Hormone Deficiency (GHD) After the Second Year of Therapy

Growth Retardation | IGHD - Isolated Growth Hormone Deficiency

Israel
Rabin Medical Center

Withdrawn

Fluids Administration During Combined Clonidine-Arginine Growth Hormone Stimulation Test

Growth Hormone Deficiency

Israel
Rambam Health Care Campus
Weizmann Institute of Science

Unknown

Exploring Interactions Between Growth Hormone and the Microbiome

Growth Hormone Deficiency

Israel
Novo Nordisk A/S

Completed

First Human Dose Trial of NNC0195-0092 (Somapacitan) in Healthy Subjects

Healthy | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
ShangHai Ji Ai Genetics & IVF Institute

Recruiting

Effect of GH on the Blastocyst Euploid Rate in AMA Patients

Preimplantation Genetic Testing | Growth Hormone | Age, Parental

China
Pfizer

Completed

Evolution Of Growth Rate In Children With Growth Retardation Due to Glucocorticosteroid Therapy And Treated By Genotonorm

Growth Hormone Deficiency

France

Clinical Trials on Growth Hormone Insensitivity Syndrome (GHIS)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Macedonia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations