Clinical Trials on Heart Valve Diseases

Total 377114 results

Woolsthorpe Technologies, LLC

Completed

Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000

Aortic Valve Disease | Mitral Regurgitation | Mitral Valve Prolapse | Congestive Heart Failure | Ischemic Cardiomyopathy | Tricuspid Regurgitation

United States
St. Antonius Hospital
ZonMw: The Netherlands Organisation for Health Research and Development

Enrolling by invitation

Evaluating Edge-to-edge Transcatheter Tricuspid Valve Repair in Patients With Severe Symptomatic Tricuspid Regurgitation (TRACE-NL)

Cardiac Catheterization | Tricuspid Valve Regurgitation, Nonrheumatic | Heart Failure, Right Sided | Valve Regurgitation, Tricuspid

Netherlands
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - First In Human Israel (TWIST-FIHIL)

Mitral Valve Regurgitation (Degenerative or Functional)

Israel
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Pilot in Georgia (TWIST-PILOT-GE)

Mitral Valve Regurgitation (Degenerative or Functional)

Georgia
Innovalve Bio Medical Ltd.

Not yet recruiting

TVMR With the Innovalve System Trial - TWIST-BE TWIST-PILOT-BE

Mitral Valve Regurgitation (Degenerative or Functional)
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Pilot Study in Italy (TWIST-PILOT-IT)

Mitral Valve Regurgitation (Degenerative or Functional)

Italy
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Early Feasibility Study (TWIST-EFS)

Mitral Valve Regurgitation (Degenerative or Functional)

United States
Innovative Cardiovascular Solutions
Yale Cardiovascular Research Group

Recruiting

Evaluation of Safety and Effectiveness of the EMBLOK EPS During TAVR

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Insufficiency | Aortic Valve Replacement

United States
Boston Scientific Corporation
Quintiles, Inc.

Withdrawn

REPRISE China - Clinical Evaluation in China

Stenoses, Aortic Valve

China
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, France, Germany, Italy, Switzerland, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE MRace: Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant (EXPLORE MRace)

Mitral Valve Disease

Brazil
P+F Products + Features GmbH
Meditrial USA Inc.

Not yet recruiting

Munich Transcatheter Mitral Valve Safety and Effectiveness (MUSE)

Mitral Regurgitation | Mitral Valve Disease

Brazil, Argentina, Chile
IRCCS Policlinico S. Donato

Not yet recruiting

Performance of Currently Available traNscaTHEter Aortic Valve Platforms in Inoperable Patients With Pure Aortic regurgitatiON of a Native Valve. The PANTHEON International Project. (PANTHEON)

Aortic Regurgitation

Italy
Nanjing First Hospital, Nanjing Medical University

Recruiting

Transcatheter Self-expandable Valve Implantation for the Treatment of Severe Native Aortic Regurgitation (SEASON-AR)

Aortic Valve Disease

China
Edwards Lifesciences

Recruiting

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial (CLASP II TR)

Tricuspid Valve Insufficiency | Tricuspid Regurgitation | Tricuspid Valve Disease

United States, Canada
Centre Hospitalier Universitaire, Amiens

Recruiting

Characteristics and Prognosis of Moderate or Severe Tricuspid Regurgitation (EPIT)

Tricuspid Valve Disease

France
Polares Medical SA

Terminated

Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (EXPLORE MR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Switzerland, Germany
HLT Inc.

Withdrawn

HLT® Meridian® TAVR Valve System Early Feasibility Study for Aortic Regurgitation (RIVAL - AR EFS)

Aortic Regurgitation

United States
JenaValve Technology, Inc.

Active, not recruiting

THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

Aortic Regurgitation

United States, Germany, Netherlands
Biostable Science & Engineering

Completed

The HAART 300 Annuloplasty Ring Trial Extended Safety and Performance

Aortic Insufficiency

Germany, Czech Republic
Edwards Lifesciences

Recruiting

TRISCEND JAPAN Study (TRISCEND JAPAN)

Cardiovascular Diseases | Heart Valve Diseases | Tricuspid Valve Regurgitation

Japan
Abbott Medical Devices

Recruiting

Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation (RESOLVE-MR)

Mitral Valve Regurgitation

Norway, United Kingdom, Saudi Arabia, France, Germany, Italy, Austria, Belgium, Czechia, Israel, Netherlands, Spain, Switzerland
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
Epygon

Recruiting

First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System

Mitral Valve Regurgitation

Spain, Austria, Italy, Serbia
HighLife SAS
MedPass International; ICON plc

Active, not recruiting

HighLife™ Transcatheter Mitral Valve Replacement System Study

Mitral Valve Insufficiency | Mitral Valve Regurgitation

France, Germany
Abbott Medical Devices

Active, not recruiting

An Observational Real-world Study Evaluating Severe Tricuspid Regurgitation Patients Treated With the Abbott TriClip™ Device (bRIGHT) (bRIGHT)

Tricuspid Valve Regurgitation

Spain, Denmark, Switzerland, Germany, Netherlands, Italy, Austria, Portugal
Edwards Lifesciences

Active, not recruiting

The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study (CLASP)

Mitral Valve Regurgitation

United States, Greece, Canada, Australia, Germany, Italy, Switzerland
Michele De Bonis

Completed

Validation of the EuroSCORE II in Open and Trans-catheter Mitral Valve Repair.

Mitral Valve Regurgitation

Italy
Mitralix

Completed

MERIT Study - Mistral Percutaneous Mitral Valve Repair FIM Study (MERIT)

Mitral Valve Regurgitation

Belgium
University of Ulm

Completed

Coronary and Structural Interventions Ulm - Transcatheter Mitral Valve Repair (CSI-Ulm-TMVR)

Mitral Valve Regurgitation

Germany
Odense University Hospital
University of Southern Denmark; Danish Heart Foundation

Unknown

Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI) (HEMI)

Mitral Valve Regurgitation

Denmark
MiCardia Corporation

Unknown

Dynamic Annuloplasty System With Activation for the Treatment of Mitral Regurgitation (DYANA)

Mitral Valve Regurgitation

Germany, Netherlands, Canada
AZ Sint-Jan AV

Not yet recruiting

TriBEL Registry: National Belgian Registry of Percutaneous Tricuspid Valve Repair Using a Transcatheter Edge-to-edge Repair Technique (TriBEL)

Tricuspid Valve Regurgitation
Fondazione GISE Onlus
University of Padova; Abbott

Recruiting

GISE Registry of Transcatheter Treatment of Mitral Valve Regurgitation With the MitraClip G4

Mitral Valve Regurgitation

Italy
Shanghai NewMed Medical Co., Ltd.

Recruiting

Mi-thos® Transcatheter Mitral Valve Replacement Study

Mitral Valve Regurgitation

China
Kephalios

Recruiting

OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety and Effectiveness Evaluation

Mitral Valve Regurgitation

Austria, Germany, Italy, Switzerland
Abbott Medical Devices

Active, not recruiting

Expanded Clinical Study of the Tendyne Mitral Valve System

Mitral Valve Regurgitation

United States, Norway, Germany, France, United Kingdom, Netherlands, Switzerland, Australia, Italy, Sweden
Edwards Lifesciences

Completed

Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System

Tricuspid Valve Regurgitation

United States
Neovasc Inc.

Active, not recruiting

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System (TIARA-I)

Mitral Valve Regurgitation

United States, Canada, Belgium
Kephalios

Completed

OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety Evaluation

Mitral Valve Regurgitation

Austria
National Heart, Lung, and Blood Institute (NHLBI)

Completed

New Techniques to Evaluate Mitral Regurgitation

Mitral Valve Regurgitation

United States
Abbott Medical Devices

Completed

Mitral Adjustable Annuloplasty Ring Feasibility and Safety Study (MAARS)

Mitral Valve Regurgitation

Netherlands, Italy, Germany
Sorin Group USA, Inc.

Completed

Safety and Efficacy Study of the Sorin 3D Annuloplasty Ring For Mitral Repair (MEMO3D)

Mitral Valve Regurgitation

United States, Canada
Cliniques universitaires Saint-Luc- Université...

Recruiting

Clinical Evaluation of the Free Margin Cusp Sizer (CALIBRATE) (CALIBRATE)

Aortic Valve Regurgitation | Aortic Root Aneurysm

Belgium
Erasmus Medical Center

Recruiting

Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort II: Structural Heart Interventions (PLUTO-II) (PLUTO-II)

Heart Failure | Aortic Stenosis | Valvular Heart Disease | Mitral Insufficiency | Tricuspid Insufficiency

Netherlands
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation

Mitral Regurgitation | Degenerative Mitral Valve Disease

China
Polares Medical SA

Terminated

Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation (EXPLORE DMR)

Degenerative Mitral Valve Disease

United States
Michele De Bonis

Completed

Commissural Closure to Treat Severe Mitral Regurgitation: Standing the Test of Time.

Degenerative Mitral Valve Disease

Italy
Hangzhou Valgen Medtech Co., Ltd

Enrolling by invitation

Safety and Effectiveness Study of Dragonfly System for Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease

China
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease

Clinical Trials on Heart Valve Diseases

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