Clinical Trials on Hematopoetic Myelodysplasia

Total 2980 results

University of Florida
Hyundai Hope On Wheels

Completed

Phase I, Dose Escalation Study of Decitabine

Leukemia, Lymphoblastic, Acute | Leukemia, Myeloid Acute | Hematopoetic Myelodysplasia

United States
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Recruiting

G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for RAEB-1,REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT

Myelodysplastic Syndrome | Allogeneic Hematopoietic Stem Cell Transplantation | Conditioning

China
Nanfang Hospital of Southern Medical University
Liuzhou Workers Hospital; Peking University People's Hospital; Sun Yat-Sen Memorial... and other collaborators

Completed

G-CSF+Decitabine+BUCY vs BUCY Conditioning Regimen for RAEB-1, REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT

Myelodysplastic Syndrome | Allogeneic Hematopoietic Stem Cell Transplantation | Conditioning

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Recruiting

G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for High-risk MDS Undergoing Allo-HSCT

Myelodysplastic Syndrome | Allogeneic Hematopoietic Stem Cell Transplantation | Conditioning

China
University Health Network, Toronto

Completed

Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/Myeloproliferative Neoplasm (DSC-SR)

Myelodysplastic/Myeloproliferative Neoplasm | Allogeneic Hematopoietic Cell Transplant | Steroid Refractory GVHD

Canada
Massachusetts General Hospital
Dana-Farber Cancer Institute; Beth Israel Deaconess Medical Center; Brigham and...

Terminated

Study of Velcade and Thalidomide in Patients With Myelodysplasia

Myelodysplastic Syndrome

United States
Centre Hospitalier Universitaire, Amiens

Completed

Development of an in Vitro Hematopoietic Culture System and Application to Myelodysplastic Syndromes. (HEMASTEM)

Myelodysplastic Syndromes | Hematopoietic Cell Proliferation

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

INSPIRE: Internet and Social-media Program With Information and Resources for Long-Term Cancer Survivors Who Underwent Stem Cell Transplant (INSPIRE)

Depression | Hematopoietic and Lymphoid Cell Neoplasm | Myelodysplastic Syndrome | Cancer Survivor

United States
Karolinska University Hospital
Nordic MDS Group

Recruiting

A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS

Myelodysplastic Syndromes | Acute Myeloid Leukemia With Myelodysplasia Related Disease and < 30% Blasts | Mixed Myelodysplastic/Myeloproliferative Disease

Sweden
Center for International Blood and Marrow Transplant...
Medical College of Wisconsin

Completed

Study of Quality of Life in Older vs. Younger Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes

Myelodysplastic Syndromes | Hematopoietic Cell Transplant

United States
University Hospital, Grenoble
Novartis

Recruiting

Evaluating Low-dose Deferasirox (DFX) in Patients With Low-risk MDS Resistant or Relapsing After ESA Agents (LODEFI)

Myelodysplasia

France
Massachusetts General Hospital
Dana-Farber Cancer Institute; Celgene Corporation

Completed

A Phase 1 Dose Escalating Trial of Bortezomib in Combination With Lenalidomide in Patients With Myelodysplasia

Myelodysplasia

United States
Peter MacCallum Cancer Centre, Australia
Celgene Corporation

Unknown

Lenalidomide and Recombinant Human Stem Cell Factor for Treatment of Myelodysplasia

Myelodysplasia

Australia
Washington University School of Medicine
National Marrow Donor Program; Predictive BioDiagnostics, LLC

Completed

Study for the Evaluation of a GVHD Negative Outcome Score (GNOS) in Matched Unrelated or Haploidentical Hematopoietic Stem Cell Transplant

Hematopoietic Stem Cell Transplantation | Stem Cell Transplantation, Hematopoietic | Transplantation, Hematopoietic Stem Cell

United States
Randy Windreich

Completed

Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS) | Hematopoietic Stem Cell Transplant (HSCT)

United States
Saint-Louis Hospital, Paris, France
University Hospital, Clermont-Ferrand; University Hospital, Grenoble; Hospital...

Completed

Allogeneic Hematopoietic Stem Cell Transplantation Evaluation in High Risk Myelodysplasia: an Observational Non-interventional Study (ONIalloMDS)

Myelodysplasia

France
Emory University

Withdrawn

Patient-Driven Transfusion Thresholds in Hematological Disorders: A Pilot Study

Hematopoietic and Lymphoid Cell Neoplasm | Leukemia | Anemia | Myelodysplastic Syndrome | Aplastic Anemia | Bone Marrow Failure

United States
Sherif S. Farag
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Acute Lymphoid Leukemia | Leukemia, Myelogenous, Chronic | Hematopoetic Myelodysplasia

United States
University Hospital, Geneva

Recruiting

Precision Dosing of Busulfan in Children Undergoing HSCT (BuGenes01)

Allogeneic Hematopoietic Stem Cell Transplantation | Hematopoietic Stem Cell Transplantation | Autologous Hematopoietic Stem Cell Transplantation

Switzerland
Merck Sharp & Dohme LLC

Terminated

Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED)

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic | Myelodysplasia | Myelomonocytic
Wuhan Union Hospital, China

Recruiting

Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Allogeneic Hematopoietic Stem Cell Transplantation | Acute Myeloid Leukemia, Adult | Myelodysplastic Syndrome(MDS)

China
Sherif Farag

Withdrawn

Azacitidine Plus Nivolumab Following Reduced-intensity Allogeneic PBSC Transplantation for Patients With AML and High-risk Myelodysplasia

Aml | AML, Adult
Dana-Farber Cancer Institute

Not yet recruiting

Peer Support Intervention for Patients Undergoing Hematopoietic Stem Cell Transplantation (STEPP)

Hematopoietic Malignancy | Hematopoietic Neoplasms

United States
Hongnan Mo

Unknown

Recombinant Human Thrombopoietin for Mobilization of Peripheral Blood Progenitor Cells for Autologous Transplantation

Hematopoietic Stem Cell Transplantation | Thrombocytopoietin | Hematopoietic Stem Cell Mobilization

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Pfizer; The Leukemia and Lymphoma Society

Terminated

A Phase 1 Trial of TST of PD 0332991 Followed by Cytarabine and Mitoxantrone for Adults With Relapsed and Refractory Acute Leukemias and High-Risk Myelodysplasia

Refractory Acute Leukemia | Relapsed Acute Leukemia | High-Risk Myelodysplasia

United States
Johann Wolfgang Goethe University Hospital
Institut für Sportwissenschaften, Frankfurt; Fresenius University of Applied...

Completed

Physical Exercise Therapy in Pediatric Stem Cell Transplantation (BISON)

Hematopoetic Stem Cell Transplantation

Germany
Charlotte Niemeyer, MD

Completed

Serial Analysis of Chimerism in Patients With Refractory Cytopenia (RC) Transplanted With Reduced Intensity Conditioning (RIC)

Myelodysplastic Syndrome (MDS) | Refractory Cytopenia of Childhood | Hematopoietic Stem Cell Transplantation (SCT) | Reduced Intensity Conditioning (RIC)

Germany
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Therapy-Related Acute Myeloid Leukemia | Acute Myeloid Leukemia With Myelodysplasia-Related Changes

United States
The First Affiliated Hospital of Soochow University

Recruiting

Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Myeloid Leukemia and Myelodysplastic Syndromes Undergoing Allo-HSCT

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Allogeneic Hematopoietic Stem Cell Transplantation

China
Capital Research Institute of Pediatrics

Unknown

Modified Post-Transplant Cyclophosphamide Regimen for Children With Juvenile Myelomonocytic Leukemia

Hematopoietic System--Cancer
Brown University
Memorial Hospital of Rhode Island; Roger Williams Medical Center

Terminated

Decitabine, Cytarabine, GCSF for Refractory AML/MDS

Leukemia | Myelodysplasia

United States
National Cancer Institute (NCI)

Active, not recruiting

Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Previously Treated Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Secondary Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia,...

United States
Universitaire Ziekenhuizen KU Leuven

Unknown

Belgian Cross-sectional Allogeneic Transplant Survivor Study (BE-C@TS)

Hematopoietic Stem Cell Transplantation | Hematopoietic Stem Cell Transplantation, Allogeneic
Sunnybrook Health Sciences Centre
Queen's University; Ontario Molecular Pathology Research Network

Unknown

Mutational Analysis as a Prognostic and Predictive Marker of Cardiovascular (CVD) Disease in Patients With Myelodysplasia

Cardiovascular Diseases | Inflammation | MDS

Canada
National Cancer Institute (NCI)

Not yet recruiting

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | Acute Myeloid Leukemia Post Cytotoxic Therapy | Acute Myeloid Leukemia, Myelodysplasia-Related
Jazz Pharmaceuticals

Completed

A Post-Marketing Observational Study of VYXEOS™

Therapy-Related Acute Myeloid Leukemia | Acute Myeloid Leukemia With Myelodysplasia-Related Changes

United States
Hong Kong Children's Hospital

Recruiting

CD62L Depleted Donor Lymphocyte Infusion With T Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation

Hematopoietic Organs; Disorder

Hong Kong
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Development and Piloting an Avatar-based Intervention to Support Patients Undergoing Stem Cell Transplantation

Hematopoietic Cell Transplantation

United States
Wake Forest University Health Sciences

Completed

Interactive Group Drumming (IGD) in Hospital Experience of Patients Undergoing Hematopoietic Stem Cell Transplant - A Pilot Study

Hematopoietic Cell Transplant

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic Syndromes

Acute Leukemia | Myelodysplasia | Chronic Leukemia

United States
Nationwide Children's Hospital

Active, not recruiting

Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic Malignancies and Myelodysplasia

Hematologic Malignancy | Myelodysplasia

United States
medac GmbH
Synteract, Inc.

Recruiting

Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics

Myelodysplastic Syndrome (MDS) | Acute Myeloid Leukaemia (AML) | Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab and Ipilimumab After Donor Stem Cell Transplant in Treating Patients With High Risk Refractory or Relapsed Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation Recipient

United States
Hong Kong Children's Hospital
The University of Hong Kong; Hong Kong Sanatorium & Hospital

Recruiting

Total Lymphoid Irradiation as Conditioning for Pediatric Haploidentical Hematopoietic Stem Cell Transplantation

Hematopoietic Organs; Disorder

Hong Kong
Mayo Clinic
Arizona State University

Active, not recruiting

Physical Activity Intervention for Hematopoietic Cell Transplant Recipients and Caregivers

Hematopoietic Cell Transplant

United States
Columbia University
Nemours Children's Clinic; Johns Hopkins All Children's Hospital

Completed

Probiotic Use in Children Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

Hematopoietic Organs; Disorder

United States
Alejandro Lucia
Hospital General Universitario Gregorio Marañon; Hospital Infantil Universitario... and other collaborators

Not yet recruiting

Exercise and Health Counseling in Pediatric Hematopoietic Stem Cell Transplantation (HENKO)

Hematopoietic System--Cancer

Spain
Emory University
Incyte Corporation

Recruiting

Virtual Rehabilitation in HCT

Hematopoietic Cell Transplant

United States
Leland Metheny

Available

Access Protocol. Infusion of CD34+ Enriched, T Cell Depleted Hematopoietic Stem Cell Grafts.

Hematopoietic/Lymphoid Cancer

United States
Fondazione Italiana Sindromi Mielodisplastiche-ETS

Completed

Identification of Mechanism in the Erythroid Response in Patients With Myelodysplasia Undergoing Chelation Therapy (BIOFER12)

Myelofibrosis | Aplastic Anemia | Myelodysplasia

Italy

Clinical Trials on Hematopoetic Myelodysplasia

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