Clinical Trials on Hepatic Tumor

Total 19850 results

Quantum Surgical

Completed

Multicenter Study to Evaluate a New Robotic Device for Image-guided Percutaneous Needle Placement

Hepatic Tumor

France
University Hospital, Montpellier

Completed

Impact of New Interventional Imaging Modality Use on Patient Radiation Exposure in Transarterial Chemoembolization

Hepatic Tumor

France
National Taiwan University Hospital

Recruiting

Anesthesia on Gut Microbiota and Metabolomics

Hepatic Tumor Resection

Taiwan
Centre Hospitalier Universitaire de Nīmes

Completed

Evaluation of the Reproducibility of Ablation Volumes at One Month After Microwave Treatment Compared to the Manufacturer's Abacus: on the Kidney, Liver and Lung (Ablation)

Renal Tumor | Hepatic Tumor

France
Mauna Kea Technologies

Unknown

Robotic Endomicroscopy to Better Define Resection Strategies Applied to Hepatic Surgery (PERSEE)

Hepatocarcinoma | Hepatic Tumor | Hepatic Metastasis

France
H. Lundbeck A/S

Completed

Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects

Heptic Impairment

Germany
Bibo Wang
Eastern Hepatobiliary Surgery Hospital

Completed

Butorphanol in Pain Following Ablation for Hepatic Tumor

Visceral Pain | Hepatic Tumor | Microwave Ablation

China
PharmaMar

Recruiting

Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment

Hepatic Impairment | Advanced Solid Tumor

Spain
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment

Cancer | Solid Tumor | Hepatic Impairment

United States
Nektar Therapeutics

Completed

A Study in Cancer Patients With Hepatic Impairment to Evaluate the Pharmacokinetics and Safety of NKTR-102 (Etirinotecan Pegol)

Advanced or Metastatic Solid Tumors in Patients With Hepatic Impairment

United States
Epizyme, Inc.
Sponsor GmbH

Recruiting

A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function

Hepatic Impairment | Advanced Malignant Solid Tumor

France, Belgium, United States, Poland, Slovakia
Sun Yat-sen University

Completed

Assessment of Hepatic Fibrosis by Shear Wave Elastography in Patients With Liver Malignancy: A Prospective Single-center Study

Hepatic Fibrosis | Liver Tumor
Novartis Pharmaceuticals

Completed

Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic Function

Hepatic Impairment | Solid Tumors

Belgium, Germany, Netherlands, Italy, Singapore, United States
AstraZeneca

Completed

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Solid Tumors

United States
Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

Liver Failure | Advanced or Metastatic Solid Tumor

France, United States
AeRang Kim

Active, not recruiting

MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Desmoid Tumor | Germ Cell Tumor | Relapsed Pediatric Solid Tumors | Refractory Pediatric Solid Tumors | Hepatic Tumor

United States
Advanced Accelerator Applications

Completed

A Study Comparing Treatment With 177Lu-DOTA0-Tyr3-Octreotate to Octreotide LAR in Patients With Inoperable, Progressive, Somatostatin Receptor Positive Midgut Carcinoid Tumours (NETTER-1)

Carcinoid Tumor of the Small Bowel | Neuroendocrine Tumour

United States, United Kingdom, Italy, Belgium, France, Germany, Portugal, Spain
National Cancer Institute (NCI)

Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Solid Tumor | Refractory Solid Tumors | Malignant Solid Tumors | Other Neoplasms Solid Tumors | Pediatric Solid Tumor

United States
Istituto Clinico Humanitas

Terminated

Methylprednisolone N Acetylcysteine in Hepatic Resections (MENHIR)

Ischemic Reperfusion Injury | Liver Tumour | Insufficiency; Hepatic, Postoperative

Italy
University of Miami

Completed

Follow-up Yttrium-90 Internal Pair Production PET/CT vs Brehmsstrahlung Imaging in Patients With Primary/Metastatic Liver Tumors

Liver Cancer | Hepatic Tumors

United States
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
Peking University People's Hospital

Completed

To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
Mayo Clinic

Completed

MR-Guided Laser Ablation of Hepatic Tumors

Soft Tissue Tumors

United States
AeRang Kim

Terminated

A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors

Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Solid Tumors | Pediatric Cancer | Rhabdomyosarcoma | Wilms Tumor | Soft Tissue Sarcomas | Germ Cell Tumors | Hepatic Tumor

United States
Chinese University of Hong Kong

Terminated

Irreversible Electroporation for Inoperable Hepatic and Pancreatic Malignancy (IRE)

Pancreatic Cancer | Hepatic Malignant Tumors

Hong Kong
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
University Medical Center Goettingen

Recruiting

Pelvic Cancer Registry for Online Adapted Radiotherapy (PRoART)

Pelvic Tumor | Thoracic Tumor

Germany
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Severe Hepatic Impairment | Normal Hepatic Function

Bulgaria
Pfizer

Completed

Pharmacokinetics Of Orally Administered Fx-1006A In Subjects With Hepatic Dysfunction

Mild Hepatic Dysfunction | Moderate Hepatic Dysfunction

South Africa
West China Hospital

Recruiting

Deep Learning Magnetic Resonance Imaging Radiomics for Diagnostic Value of Hepatic Tumors in Infants

Hepatoblastoma | Hepatic Hemangioendothelioma

China
Elpiscience Biopharma, Ltd.

Active, not recruiting

A Study of ES102 (OX40 Agonist) in Patients With Advanced Solid Tumors

Neoplasms | Solid Tumors | Malignant Tumor

China
Elpiscience Biopharma, Ltd.

Terminated

A Study of ES101 (PD-L1x4-1BB Bispecific Antibody) in Patients With Advanced Solid Tumors

Neoplasms | Solid Tumors | Malignant Tumor

China
Centre Hospitalier Universitaire, Amiens
Assistance Publique - Hôpitaux de Paris

Unknown

Optimization of Health Expenditure in Liver Surgery

Hepatocellular Carcinoma | Hilar Cholangiocarcinoma | Liver Metastasis | Intra Hepatic Cholangiocarcinoma

France
Shanghai Children's Medical Center
The First Affiliated Hospital of Anhui Medical University; Zhengzhou Children... and other collaborators

Completed

PIVKA-II Combined With Alpha-Fetoprotein for Diagnostic and Prognostic Value of Hepatic Tumors in Infants (PIVKA-II)

Hepatoblastoma | Hepatic Hemangioendothelioma

China
Denver Health and Hospital Authority
University of Colorado, Denver; Johnson & Johnson Consumer Inc., McNeil Consumer... and other collaborators

Withdrawn

APAP-CYS Protein Adduct Concentrations in Patients With Liver-Directed Therapy Intended to Treat Hepatic Tumors

Acetaminophen Exposure

United States
Hong Kong Children's Hospital

Recruiting

Ultrasound Measurements of Hepatic Vasculatures and Hepatic Doppler Assessment of Healthy Children

Portal Vein | Hepatic Veins | Hepatic Artery | Liver Circulation

Hong Kong
Dana-Farber Cancer Institute
Massachusetts General Hospital; Novartis; Beth Israel Deaconess Medical Center; Brigham and Women's Hospital

Completed

Pasireotide in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors

Neuroendocrine Tumor | Carcinoid Tumor | Pancreatic Neuroendocrine Tumor

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Healthy Volunteers | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
Roswell Park Cancer Institute
NeuroEndocrine Tumor Research Foundation (NETRF)

Recruiting

Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors

Lung Atypical Carcinoid Tumor | Metastatic Pancreatic Neuroendocrine Tumor | Lung Typical Carcinoid Tumor

United States
Dana-Farber Cancer Institute
Bayer; Novartis

Completed

Sorafenib in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors

Neuroendocrine Tumor | Carcinoid Tumor | Pancreatic Neuroendocrine Tumor

United States
AstraZeneca

Completed

An Open-Label, Dose-Escalation Study of AZD2461

Refractory Solid Tumors | Cancer Tumor

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of Paris (DEVINHEF)

Fulminating Hepatic Failure

France
Vanquish Oncology, Inc.
University of Illinois at Chicago

Completed

Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 1

Solid Tumor | Neuroendocrine Tumors | Pancreatic Neuroendocrine Tumor

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Study of ZG2001 in Participants With KRAS Mutated Advanced Solid Tumours

Solid Tumor | KRAS Mutation-Related Tumors

China
Eisai Inc.

Completed

A Pharmacokinetic and Safety Study of E7080 in Subjects With Mild (10 mg), Moderate (10 mg), and Severe Hepatic Impairment (5 mg) and Normal Hepatic Function (10 mg)

Hepatic Impairment | Hepatic Function

United States
Georgetown University
Immune System Key Ltd

Recruiting

NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors

Solid Tumor | KRAS Mutation-Related Tumors

United States
National Cancer Institute (NCI)

Recruiting

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus Everolimus in Patients With Metastatic Unresectable Midgut Neuroendocrine Tumors, NET RETREAT Trial

Metastatic Midgut Neuroendocrine Tumor | Unresectable Midgut Neuroendocrine Tumor | Metastatic Midgut Neuroendocrine Tumor G1 | Metastatic Midgut Neuroendocrine Tumor G2

United States, Canada
Agios Pharmaceuticals, Inc.

Completed

A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function

Moderate Hepatic Impairment

United States

Clinical Trials on Hepatic Tumor

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