Example: Heart Attack

Clinical Trials on Heredodegenerative Disorders, Nervous System

Total 1276 results

NCT00006176

Completed

Clinical and Genetic Studies of Familial Presenile Dementia With Neuronal Inclusion Bodies

Conditions: Familial Dementia With Neuroserpin Inclusion Bodies; Nervous System Heredodegenerative Disorder
NCT03109301

Withdrawn

Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

Conditions: Neoplasms, Nerve Tissue; Neurofibromatosis 1; Heredodegenerative Disorders, Nervous System; Peripheral Nervous System Diseases
NCT04601051

Not yet recruiting

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN)

Conditions: Hereditary Transthyretin Amyloidosis; Amyloid Neuropathies, Familial; Heredodegenerative Disorders, Nervous System; Neurodegenerative Diseases, Nervous System Diseases; Amyloid Neuropathies; Peripheral Nervous System Diseases; Genetic Diseases, Inborn; Amyloidosis, Familial; Metabolism, Inborn Errors; Proteostasis
NCT02429947

Completed

An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients

Conditions: Charcot Marie Tooth Disease (CMT); Hereditary Sensory and Motor Neuropathy; Nerve Compression Syndromes; Tooth Diseases; Congenital Abnormalities; Genetic Diseases, Inborn; Heredodegenerative Disorders, Nervous System
NCT01485965

Completed

A Open-label Food Effect Study With SEN0014196 in Subjects With Huntington Disease

Conditions: Huntington's Disease
NCT01485952

Completed

An Exploratory Clinical Trial in Early Stage Huntington's Disease Patients With SEN0014196

Conditions: Huntington Disease
NCT04594590

Not yet recruiting

Natural History Study of SLC25A46 Mutation-related Mitochondriopathy

Conditions: Neurodegenerative Disease, Hereditary; Mitochondrial Diseases; Optic Atrophy
NCT04580979

Not yet recruiting

Natural History Study of FDXR Mutation-related Mitochondriopathy

Conditions: Neurodegenerative Disease, Hereditary; Mitochondrial Diseases; Optic Atrophy
NCT03332030

Suspended

Stem Cells in NF1 Patients With Tumors of the Central Nervous System

Conditions: Neurofibromatosis Type 1; Tumors of the Central Nervous System
NCT01558479

Unknown status

The Parkinson's Genetic Research Study

Conditions: Parkinson's Disease
NCT04014244

Not yet recruiting

Dextrose, Corticosteroids and Surgical Release in Carpal Tunnel Syndrome

Conditions: Peripheral Nervous System Diseases; Nerve Compression Syndromes; Carpal Tunnel Syndrome
NCT03651609

Recruiting

Treatment for Ulnar Neuropathy at the Elbow

Conditions: Peripheral Nervous System Diseases; Nerve Compression Syndromes; Cubital Tunnel Syndrome
NCT02415153

Active, not recruiting

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Conditions: Neurofibromatosis Type 1; Recurrent Childhood Brain Stem Glioma; Recurrent Childhood Visual Pathway Glioma; Recurrent Primary Central Nervous System Neoplasm; Refractory Primary Central Nervous System Neoplasm
NCT01222728

Completed

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

Conditions: Neoplasms; Nervous System Disease; Vestibular Disease
NCT02750982

Completed

Laughter Therapy Effects on Mood, Stress and Self-efficacy in People With Neurological Diseases.

Conditions: Alzheimer's Disease; Amyotrophic Lateral Sclerosis; Brain Injury; Huntington's Disease; Multiple Sclerosis; Parkinson's Disease; Stroke; Spinal Cord Injury
NCT00937794

Completed

Screening Study to Identify Pediatric Patients With Hunter Syndrome Who Demonstrate Evidence of Central Nervous System (CNS) Involvement and Who Are Currently Receiving Treatment With Elaprase®

Conditions: Hunter Syndrome
NCT00352495

Completed

Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

Conditions: Brain and Central Nervous System Tumors; Neurofibromatosis Type 1
NCT02876939

Completed

Proprioception and Sensorimotor Control in Hereditary Sensory and Autonomic Neuropathy

Conditions: Atunomic Neuropathy
NCT03363217

Recruiting

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Conditions: Low-grade Glioma; Plexiform Neurofibroma; Central Nervous System Glioma
NCT02994719

Active, not recruiting

Gait Analysis in Neurological Disease

Conditions: Parkinson's Disease; Parkinsonian Disorders; Atypical Parkinson Disease; Progressive Supranuclear Palsy; Multiple System Atrophy; Corticobasal Degeneration; Gait, Frontal; Huntington Disease
NCT01238315

Withdrawn

Safety and Efficacy Study of HuCNS-SC in Subjects With Neuronal Ceroid Lipofuscinosis

Conditions: Neuronal Ceroid Lipofuscinosis
NCT01733407

Completed

L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1

Conditions: Hereditary Sensory and Autonomic Neuropathy Type I
NCT02362438

Recruiting

Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy

Conditions: Giant Axonal Neuropathy; Gene Transfer
NCT02553265

Completed

Carbidopa for the Treatment of Excessive Blood Pressure Variability

Conditions: Dysautonomia, Familial; Baroreflex Failure Syndrome
NCT01963650

Terminated

Natural History Study of Children With Metachromatic Leukodystrophy

Conditions: Lipid Metabolism Disorders; Metachromatic Leukodystrophy (MLD); Nervous System Diseases; Brain Diseases; Central Nervous System Diseases; Demyelinating Diseases; Metabolism, Inborn Errors; Genetic Diseases, Inborn; Sphingolipidoses; Hereditary Central Nervous System Demyelinating Diseases; Metabolic Inborn Brain Diseases; Lysosomal Storage Diseases; Metabolic Diseases; Sulfatidosis