Clinical Trials on High Risk of Significant Coronary Artery Disease

Total 6516 results

University Hospital Plymouth NHS Trust

Completed

Cardiac GSI Feasibility Study

High Risk of Significant Coronary Artery Disease

United Kingdom
Boston Children's Hospital

Completed

FITT Exercise Counseling With Interactive Accelerometry and Physical Activity in Adolescents at Increased Risk of Early Cardiovascular Disease: A Pilot Study

Coronary Artery Disease Risk High

United States
Humanitas Hospital, Italy

Recruiting

Implementation of Contemporary Coronary CT Angiography in Clinical Practice (CONCORDE)

Coronary Arteriosclerosis | Coronary Syndrome | Coronary Artery Disease of Significant Bypass Graft

Italy
Xijing Hospital

Recruiting

Interventional Ventricular Assist System for PCI in CHIP Patients (REC-CHIPMCS)

High-Risk Percutaneous Coronary Intervention (High-risk PCI) | Left Ventricular Assist Devices

China
AstraZeneca

Completed

A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet

High Risk Coronary Artery Disease

United Kingdom
Abbott Medical Devices

Completed

HeartMate PHP™ CE Mark Clinical Investigation Plan (HM PHP CE Mark)

High Risk Percutaneous Coronary Intervention

Colombia, Netherlands, Paraguay, Poland
Abiomed Inc.

Enrolling by invitation

Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

High-Risk Percutaneous Coronary Intervention

United States
Magenta Medical Ltd.

Recruiting

Magenta Elevate™ EFS in High-Risk PCI Patients

High-risk Percutaneous Coronary Intervention

United States
Abiomed Inc.

Active, not recruiting

Impella ECP Early Feasibility Study (ECP EFS)

High-risk Percutaneous Coronary Intervention

United States
Magenta Medical Ltd.

Active, not recruiting

Magenta Elevate™ First-in-Human Clinical Study in High-Risk PCI Patients (ELEVATE I)

High-Risk Percutaneous Coronary Intervention

Georgia
Hospital San Carlos, Madrid
Laboratorios Farmacéuticos Rovi, S.A.; S&H MEDICAL SCIENCE SERVICE, S.L.

Active, not recruiting

Registry of Secondary Revascularization (REVASEC)

Coronary Arteriosclerosis | Stent Stenosis | Coronary Artery Disease Progression | Stent Restenosis | Coronary Artery Disease of Significant Bypass Graft

Spain
Instituto Nacional de Cardiologia Ignacio Chavez

Terminated

Drug-eluting Balloon Versus Drug-eluting Stent for High Bleeding Risk Angioplasty (DEBORA)

Coronary Artery Disease (CAD) | Percutaneous Coronary Intervention (PCI) | High Bleeding Risk

Mexico
Biotronik France
MedPass International

Unknown

PaneLux PTCA : Proposing an Alternative Treatment to patiEnts for Whom DES Implantation is Not Indicated, Thanks to Pantera LUX Drug Eluting Balloon (PaneLux PTCA)

Coronary Artery Disease | High Bleeding Risk Patients

France
Beijing Anzhen Hospital

Unknown

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With High Risk Coronary Artery Disease (FORWARD) (FORWARD)

Dyslipidemia | High Risk Coronary Artery Disease

China
Biosensors Europe SA

Recruiting

ULTRA LONG: BioFreedom Ultra

Coronary Artery Disease | High Bleeding Risk Patients

United Kingdom
University of Évora
São João de Deus School of Nursing; Horizon 2020 - Portugal 2020 (ALT20-03-0145-FEDER-000007...

Completed

Multimodal Exercise Programs for Fall Prevention: A Randomized Controlled Trial

Fallers | High Risk of Falling

Portugal
Instituto Nacional de Cardiologia Ignacio Chavez

Recruiting

Zotarolimus vs Sirolimus Eluting Stent in High Bleeding Risk (ZEVS-HBR)

Coronary Artery Disease | Percutaneous Coronary Intervention | High Bleeding Risk

Mexico
Aarhus University Hospital Skejby

Active, not recruiting

Coronary Hybrid Revascularisation Study

Significant Coronary Artery Disease

Denmark
University of Chicago
Northwestern University; University of Illinois at Chicago; Rush University Medical... and other collaborators

Active, not recruiting

Comprehensive Care Physician: Integrated Inpatient and Outpatient Care for Patients at High Risk of Hospitalization (CCP)

Medicare Patients | High Risk of Hospitalizations

United States
ECRI bv
University of Bern; European Cardiovascular Research Center; Terumo Medical Corporation and other collaborators

Completed

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen (MASTER DAPT)

Coronary Artery Disease | PCI | High Bleeding Risk

Netherlands, France, United Kingdom, Australia, Singapore, Japan, Italy, Poland, Spain, Switzerland, Israel, Argentina, Austria, Bahrain, Bangladesh, Belgium, Bulgaria, Czechia, Denmark, Estonia, Germany, Hungary, India, Korea, Republic... and more
Hadassah Medical Organization

Unknown

Fertility Preservation by Ovarian and Oocyte Cryopreservation (HFPP)

Female Patients Aged 5-35 Prior to Systemic Chemotherapy | With Significant Risk of Ovarian Toxicity

Israel
Federal State Budgetary Institution National Medical...
Kemerovo Cardiology Center, Tarasov Roman Sergeevich; Tomsk National Research...

Recruiting

Management Tactics for Patients High Risk With Acute Coronary Syndrome Without ST Segment Elevation and Multivessel Coronary Artery Disease (NSTE-ACSMT)

Coronary Syndrome, Acute, Non-ST Elevation, High Risk Patients

Russian Federation
Queen's University, Belfast

Completed

Pharmacist-led Medicines Management Outpatient Service (MMC)

Patients at High Risk of Medicine-related Problems

United Kingdom
University Hospital, Montpellier

Not yet recruiting

Impact of Assessment and Management of Comorbidities in Internal Medicine on Cardiovascular Risk (COMMEDCARDIO)

Patients at High-Risk of a Cardiovascular Event
Meir Medical Center

Unknown

The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies

High Risk Pregnancies | Telomere Length | Mechanisms of Telomter Homeostasis

Israel
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Laboratory Implications of Non Obstructive Atherosclerotic Plaques Identified by Multiple Detector Coronary Angiotomography

Cardiovascular Risk Factor | Platelet Aggregation, Spontaneous | Discrete Coronary Artery Stenosis | Coronary Angiography of Multiple Detectors

Brazil
Institut Curie

Completed

Use of Specific Genetic Alteration s of Tumoral Cells Identified by the Next Generation Sequencing Techniques (NGS) to Follow Peripheral Samples of Children With Metastatic and/or High Risk Solid Tumor - NGSKids (NGSKids)

Metastatic and/or High Risk Solid Tumor of Children

France
Wake Forest University Health Sciences

Completed

Validation and Implementation Design of an Epic Systems 30-day Unplanned Readmission Risk Model

Unplanned Hospital Readmissions | Patients at High Risk of Unplanned Readmission

United States
Yonsei University

Not yet recruiting

Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >75 Years: the SCOPE-75 RCT Study

Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease

Korea, Republic of
Boston Scientific Corporation

Not yet recruiting

VITALYST Early Feasibility Study in High-Risk PCI Patients (VITALYST EFS) (VITALYST EFS)

Heart Disease, Coronary | High-risk Percutaneous Coronary Intervention

United States, Sweden
Air Liquide Santé International
Eurofins Biomnis; MONITORING FORCE GROUP CROs; Inferential

Completed

Cardiovascular Safety of Xenon in General Anaesthesia, in Patient With Cardiovascular Risk in Non Cardiac Surgery (CARVASAXe)

Elevated Cardiac Risk | Coronary Arteries Disease Risk

France
Tryton Medical, Inc.

Completed

Prospective, Single Blind, Rand Controlled Study to Evaluate the Safety & Effectness of Tryton Side Branch Stent Used With DES Treatmt of de Novo Bifurcation Lesions in MB & SB in Native Coronaries (TRYTON)

Coronary Atherosclerosis of Native Coronary Artery | Bifurcation Lesions: de Novo Lesions of the Main and Side Branch of Native Coronary Artery

United States
Elixir Medical Corporation
Istituto Clinico Humanitas

Active, not recruiting

DYNAMX Bioadaptor ImplanTation for the trEatment of Complex Coronary Lesions (DYNAMITE)

Coronary Artery Disease | Chronic Total Occlusion of Coronary Artery | Multi Vessel Coronary Artery Disease | Bifurcation of Coronary Artery | Long Lesions Coronary Artery Disease

Italy
Western University, Canada

Completed

Effects of Two In-hospital Antepartum Interventions on Functional Ability and Quality of Life in Early Postpartum Women.

High-Risk Pregnancy

Canada
Pi-cardia

Completed

The ShortCut™ Study Protocol

Risk of Coronary Obstruction Following TAVR Procedure

United States, Germany, Israel, United Kingdom, France
Nova Scotia Health Authority
Pfizer; Cape Breton District Health Authority

Completed

A Novel Approach to Cardiovascular Health by Optimizing Risk Management (ANCHOR) (ANCHOR)

Cardiovascular Risk Reduction of Having a Coronary Event

Canada
University of Michigan

Completed

The Seatbelt Intervention Study

High Risk Population of Part-time Seatbelt Users
Johns Hopkins University

Recruiting

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography] (PET; CT)

Coronary Artery Disease | Atherosclerosis | Coronary Atherosclerosis of Native Coronary Artery

United States
Tufts Medical Center
National Heart, Lung, and Blood Institute (NHLBI); Sinai Hospital of Baltimore

Completed

Safety Study of PZ-128 in Subjects With Multiple Coronary Artery Disease Risk Factors

Vascular Disease | Coronary Artery Disease Risk Factors Multiple

United States
National Cerebral and Cardiovascular Center

Recruiting

REASSURE-NIRS Registry (REASSURENIRS)

Lipid-Rich Atherosclerosis of Coronary Artery

Japan
Tilburg University
Elisabeth-TweeSteden Ziekenhuis; The Elisabeth-TweeSteden Hospital

Active, not recruiting

TweeSteden Mild Stenosis Study (TWIST)

Coronary Artery Disease | Non-significant Coronary Artery Disease | Mild Stenosis | Vascular Irregularities

Netherlands
Abbott Medical Devices

Completed

ABSORB FIRST is a Registry Designed to Evaluate the Safety and Performance of Absorb Bioresorbable Vascular Scaffold (Absorb BVS) Used in Real-world Patients.

Coronary Artery Disease | Coronary Disease | Coronary Occlusion | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Coronary Artery Stenosis | Coronary Artery Restenosis

Belgium
CONRAD
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Microbicide Safety and Acceptability in Young Men (Project Gel)

HIV Negative | High Risk MSM | 18-30 Years of Age

United States, Puerto Rico
Centre Hospitalier Universitaire Dijon

Terminated

Retinal Microvascularization and Cardiovascular Disease (NESTOR)

High Cardiovascular Risk Patients | Low Cardiovascular Risk Patients

France
Chinese Academy of Medical Sciences, Fuwai Hospital

Completed

A Single-center, Prospective,Randomized Study of Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Dual Anti-platelet Therapy After Coronary Artery Bypass Grafting (ATCCC)

Antiplatelet Therapy of Coronary Artery Bypass

China
Hadassah Medical Organization

Unknown

The Fusion Versus The Affinity Oxygenation Systems

Complication of Coronary Artery Bypass Graft
Recep Tayyip Erdogan University Training and Research...

Completed

TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries

High Caries Risk | Low Caries Risk

Turkey
Novosibirsk Scientific Research Institute for Circulatory...

Recruiting

The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.

to Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass Grafting

Russian Federation
University Hospital of Cologne
Karolinska Institutet; University Hospital of North Norway; Goethe University; McGill... and other collaborators

Unknown

Impact of Prescription Quality, Infection Control and Antimicrobial Stewardship on Gut Microbiota Domination by Healthcare-Associated Pathogens (PILGRIM)

Patients at High Risk of Antibacterial Treatment Upon Admission

Germany
Aristotle University Of Thessaloniki
LABNET IAE - Private Reference Diagnostic Laboratory

Unknown

Correlation of Genetic Polymorphisms and Clinical Parameters With the Complexity of Coronary Artery Disease

Coronary Artery Disease | Coronary Arteriosclerosis | Cardiovascular Risk Factor

Greece

Clinical Trials on High Risk of Significant Coronary Artery Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Poland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations