Clinical Trials on High Thymidylate Synthase Expression

Total 26 results

Istituto Scientifico Romagnolo per lo Studio e...
Pierre Fabre Laboratories

Terminated

Open-label, Multicenter, Randomized Phase II Trial of Treatment With Cisplatin and Pemetrexed or Cisplatin and Oral Vinorelbine in Chemotherapy Naïve Patients Affected by Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer With High Thymidylate Synthase Expression (HighTySy)

Carcinoma, Non-Small-Cell Lung | Secondary | Advanced Stage IIIB | High Thymidylate Synthase Expression

Italy
University of Ulm
Pfizer, Berlin Germany; Medac, Hamburg, Germany; Study Group Oncology of Gastrointestinal...

Completed

Response Prediction in Metastasized Colorectal Cancer Using Intratumoral Thymidylate Synthase (FOGT5)

Colorectal Cancer | Biopsy | Non Resectable Metastasis | Reference Lesion | Thymidylate Synthase Quantitation

Germany
Shanghai Henlius Biotech

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of HLX07 in nsqNSCLC Patients With High EGFR Expression

HLX07, nsqNSCLC, High EGFR Expression

China
University of Malaya
Pfizer; Cancer Research Malaysia; Pantai Hospital Kuala Lumpur; Hospital Sultan...

Recruiting

Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature

Triple Negative Breast Cancer | HRD 100 Gene Expression High

Malaysia
Boston Children's Hospital

Withdrawn

Primary Care iSBIRT to Reduce Serious Teen Health Risks

Depression | Substance-related Disorders | High-risk Sex

United States
University of Colorado, Denver
Nationwide Children's Hospital; University of Rochester

Recruiting

Nurse Family Partnership for Women With Previous Live Births

Pregnancy, High Risk | Post Partum Depression | Child Development

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Recruiting

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma

Diffuse Large B-Cell Lymphoma | High-grade B-cell Lymphoma | Double Expressor Lymphoma | High Grade B-Cell Lymphoma w/MYC & BCL2 or BCL6 Rearrangements | High Grade B-Cell Lymphoma w/MYC, BCL2 & BCL6 Rearrangements

United States
Istanbul University
Istanbul University - Cerrahpasa (IUC)

Completed

The Effect of Stress Reduction Program on Pregnancy Process and Mental Health in High Risk Pregnant Women

Depression, Postpartum | Pregnancy, High Risk | Stress Disorder | Anxiety in Pregnancy

Turkey
Joseph Tuscano
National Cancer Institute (NCI); ADC Therapeutics S.A.

Recruiting

Loncastuximab Tesirine and Rituximab Followed by DA-EPOCH-R for Treating Patients With High-Risk Diffuse Large B-cell Lymphoma

High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Double-Expressor Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements

United States
Turku University Hospital
University of Turku; Academy of Finland; Foundation for Paediatric Research,... and other collaborators

Completed

A Prenatal Mentalization-focused 4D Ultrasound and a Pregnancy Diary Intervention for Substance-abusing Women

Substance-Related Disorders | Depression | Anxiety | Pregnancy, High Risk | Parenting | Maternal-Fetal Relations | Prenatal Care | Fetal Exposure During Pregnancy | Perinatal Outcome

Finland
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas

Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Double-Expressor Lymphoma | EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise... and other conditions

United States
University of Udine

Recruiting

The Supplementation Therapy in Autism and Response to Treatment Study (START)

Depressive Symptoms | Autism Spectrum Disorder | Anxiety State | Autism | Asperger Syndrome | Autism Spectrum Disorder High-Functioning

Italy
University of Turin, Italy
EMDR Europe

Recruiting

RCT Comparing EMDR and CBT for Treatment of Resistant Depression

Depression | Heart Rate Variability | Functional Magnetic Resonance Imaging | Cognitive Behavioral Therapy | Eye Movement Desensitization and Reprocessing | Neurobiological Processing | High Definition Electroencefalography

Italy
Cedars-Sinai Medical Center
University of California, Los Angeles; National Institutes of Health (NIH); Maternal... and other collaborators

Recruiting

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women (RISE)

Depression | Inflammation | Stress, Psychological | Pregnancy Complications | Depression, Postpartum | Anxiety | Pregnancy Related | Pregnancy, High Risk | Discrimination, Racial | Perinatal Depression | Anxiety in Pregnancy | Racism

United States
Norbert Hermanns
Helmholtz Zentrum München; University of Giessen; German Center for Diabetes...

Completed

Towards a Better Understanding of Diabetes Distress, Depression and Poor Glycaemic Control in T2DM (DIA-LINK2)

Diabetes Mellitus, Type 2 | Stress, Psychological | Depressive Symptoms | Glucose, High Blood

Germany
Yang I. Pachankis, PhD
S for Science

Active, not recruiting

Psychiatric Orders in Psychoanalytic Treatment of ASD

PTSD | Anxiety Disorders | OCD | Borderline Personality Disorder | Social Anxiety Disorder | Depression, Anxiety | Depression, Unipolar | ADHD - Combined Type | Grief | Depression Anxiety Disorder | Depression and Suicide | Autism Spectrum Disorder High-Functioning | Avoidant Personality Disorder | Agoraphobia With... and other conditions

China
Norbert Hermanns
Helmholtz Zentrum München; University of Giessen; German Center for Diabetes...

Completed

Towards a Better Understanding of Diabetes Distress, Depression and Poor Glycaemic Control (DIA-LINK Study) (DIA-LINK)

Diabetes Mellitus, Type 1 | Stress, Psychological | Depressive Symptoms | Glucose, High Blood

Germany
Monte Rosa Therapeutics, Inc

Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast Cancer

United States, Canada
Lisa Gallagher
The Cleveland Clinic; National Endowment for the Arts, United States; Cuyahoga...

Terminated

Arts & Health Education to Improve Health, Resilience, and Well-Being

Depression | Heart Diseases | Stroke | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Chronic Pain | Asthma | Anxiety | COPD | CHF | High Cholesterol

United States
National Center for Complementary and Integrative...

Completed

Women's Use of Alternative Medicine: A Multiethnic Study

Depression | Arthritis | Urinary Tract Infection | Osteoporosis | Heart Disease | Uterine Fibroids | High Blood Pressure | Headaches
University of Tennessee
Sponsor GmbH

Recruiting

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence (MedAAAction)

Depression | Coronary Artery Disease | Stroke | Hypertension | Diabetes | Chronic Kidney Diseases | Anxiety | Chronic Lung Disease | Pulmonary Embolism | Congestive Heart Failure | Arrythmia | Heart Attack | High Cholesterol/Hyperlipidemia

United States
Curis, Inc.
The Leukemia and Lymphoma Society

Completed

Study to Assess the Safety, Tolerability and Pharmacokinetics of Fimepinostat (CUDC-907) in Patients With Lymphoma

Lymphoma | Refractory Lymphoma | Relapsed Lymphoma | Relapsed and/or Refractory Lymphoma | Relapsed Ddiffuse Large B-Cell Lymphoma (DLBCL) | Refractory Diffuse Large B-Cell Lymphoma (DLBCL) | Relapsed and/or Refractory Diffuse Large B-Cell Lymphoma (DLBCL) | Double-hit Lymphoma (DHL) | Triple-hit Lymphoma... and other conditions

United States
BicycleTx Limited

Recruiting

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

Head and Neck Cancer | Ovarian Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Advanced Solid Tumor Historically Known for High EphA2 Expression | Urothelial Cancer | Gastric/Upper Gastrointestinal Cancer

United States, Belgium, Korea, Republic of, Spain, United Kingdom
VA Office of Research and Development

Completed

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

Depression | Insomnia | Dementia | Fibromyalgia | Anxiety | Chronic Low Back Pain | Lumbar Spinal Stenosis | Myofascial Pain Syndrome | Sacroiliac Joint Pain | Hip Ostearthritis | Maladaptive Coping | Lateral Hip and Thigh Pain | Recent Leg Length Discrepancy

United States
Universitair Ziekenhuis Brussel
Kom Op Tegen Kanker; Agentschap voor Innovatie door Wetenschap en Technologie...

Recruiting

Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma Patients (VUBAR)

Gastric Cancer | Colorectal Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Endometrial Cancer | Urothelial Carcinoma | Biliary Tract Cancer | Locally Advanced Breast Cancer | Cancer of Pancreas | Uterine Cancer | Salivary Gland Cancer | Metastatic Breast Carcinoma | Solid Tumor With Intermediate...

Belgium
Willows Health
Nottingham Trent University

Not yet recruiting

Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) (BRANCH-P)

Depression | Heart Diseases | Cardiovascular Diseases | HIV Infections | Obesity | Diabetes | Cancer | Chronic Kidney Diseases | Arthritis | Bulimia | Alzheimer Disease | Cellulitis | Cirrhosis | Eczema | Osteoporosis | Appendicitis | Bronchitis | Bowel Disease | Gout | Alcoholic Liver Disease | Flu | High Cholesterol | Allergies | Indigestion | ... and other conditions

United Kingdom

Clinical Trials on High Thymidylate Synthase Expression

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