Clinical Trials on Hyperkalemic Periodic Paralysis

Total 2115 results

University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Hyper- and Hypokalemic Periodic Paralysis Study (HYP-HOP)

Hyperkalemic Periodic Paralysis | Hypokalemic Periodic Paralysis

United States, Italy, United Kingdom
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders

Paralysis, Hyperkalemic Periodic | Paramyotonia Congenita | Hypokalemic Periodic Paralysis
Grete Andersen, MD

Completed

Lamotrigine as Treatment of Myotonia

Hyperkalemic Periodic Paralysis | Myotonia Congenita | Paramyotonia Congenita | Dystrophia Myotonica Type 1 | Potassium-Aggravated Myotonia

Denmark
University College, London

Terminated

Bumetanide in Hypokalaemic Periodic Paralysis

Hypokalemic Periodic Paralysis

United Kingdom
Institut National de la Santé Et de la Recherche...

Recruiting

Utility and Validation's Study of a Smartphone Application for Periodic Paralysis (RaDiCo-PP)

Periodic Paralyses

France
AstraZeneca

Active, not recruiting

A Multicenter, Prospective, Non-interventional Cohort Study to Evaluate the Safety and Treatment Pattern of Sodium Zirconium Cyclosilicate for Hyperkalaemia Management in Real World Practice in China (ACTUALIZE)

Hyperkalaemia

China
AstraZeneca

Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia (PEDZ-K)

Hyperkalaemia

China, Germany, United States, Ukraine, Spain, Japan, United Kingdom, Canada, Poland, Romania, Russian Federation, Brazil
West China Hospital

Unknown

Genetic and Morphological Analysis of Thyrotoxic Periodic Paralysis

Thyrotoxic Periodic Paralysis
AstraZeneca

Terminated

Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia (GRAZE)

Hyperkalaemia

United States
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
Ramathibodi Hospital

Completed

Genetic Analysis of Thyrotoxic Periodic Paralysis

Thyrotoxic Periodic Paralysis
Medical University of Vienna

Completed

Perioperative Fluid Management in Patients Receiving Cadaveric Renal Transplants

Metabolic Acidosis | Hyperkalaemia Requiring Postoperative Dialysis

Austria
AstraZeneca

Active, not recruiting

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone (REALIZE-K)

Heart Failure With Reduced Ejection Fraction | Hyperkalaemia

United States, Spain, Canada, Brazil, Hungary, Czechia, Ukraine, Poland, United Kingdom
Hacettepe University

Completed

Motivation's Effect on Home Exercise in Children With OBPP

Obstetric Paralyses
St George's, University of London

Recruiting

Lokelma for RAAS Maximisation in CKD & Heart Failure. (LIFT)

Chronic Kidney Diseases | Heart Failure With Reduced Ejection Fraction | Hyperkalemia | ACE Inhibitor Induced Hyperkalaemia | Mineralocorticoid Resistant Hyperkalemia

United Kingdom
AstraZeneca

Completed

Safety of Oral Resin for Treatment of Hyperkalemia in Chinese Patients With Renal Insufficiency (SCRUTINIZE)

Hyperkalaemia

China
Centre Integre Universitaire de Sante et Services...
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Evidence for Potassium Restriction in Hemodialysis (EvoKe-HD)

Hyperkalemia, Diminished Renal Excretion

Canada
AstraZeneca

Completed

Retrospective Study to Describe Prevalence of Hyperkalemia in Russian Population Based on Large Laboratory Network (HEKATE)

Hyperkalemia Elevated Plasma K+ Cardiovascular Disease (CVD)

Russian Federation
Portsmouth Hospitals NHS Trust
Vifor Pharma

Recruiting

Hyperkalaemia and Its Impact on Therapy With RAASi (REVIEW)

Heart Failure With Reduced Ejection Fraction | Left Ventricular Systolic Dysfunction | Hyperkalaemia

United Kingdom
Zydus Lifesciences Limited

Completed

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZYIL1 in Subjects With Cryopyrin Associated Periodic Syndromes (CAPS)

Cryopyrin Associated Periodic Syndrome

Australia
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Associação Fundo de Incentivo...

Completed

Dopamine Transporter Density Profiles in Patients With Periodic Limb Movements (DOPATRANSPLM)

Periodic Limb Movements in Sleep

Brazil
Inflazome UK Ltd

Completed

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With IZD334

Healthy Volunteers | Cryopyrin Associated Periodic Syndrome

Australia
University of California, Irvine

Recruiting

Comparison of Potassium Binders in the ER (KBindER)

Acute Hyperkalemia | Oral Potassium Binders

United States
Assistance Publique - Hôpitaux de Paris
Institut Imagine

Not yet recruiting

Are Mast Cells Involved in Autoinflammatory Diseases (INFLAMAST)

Autoinflammatory Disease | FMF | TRAPS | MKD | Cryopyrin Associated Periodic Syndrome | Haploinsufficiency

France
University Hospital, Montpellier
Centre Hospitalier Universitaire de Nīmes; National University of Ireland,... and other collaborators

Completed

BCI Post-stroke Neurorehabilitation (BCI-stroke)

Paralytic Stroke | Poststroke/CVA Hemiparesis | Hand Flaccid Paralysis

France
Umm Al-Qura University

Recruiting

Multiwave Locked System Laser for Patients With Bell's Palsy. (MLS)

Laser Therapy | Bell Palsy | Facial Paralyses, Idiopathic

Saudi Arabia
China Medical University Hospital

Completed

Effect of Laser Acupuncture Treatment on Chronic Facial Paralysis

Bell Palsy | Idiopathic Facial Paralyses

Taiwan
University Hospital, Lille

Completed

Adult Outcomes of Children With CAPS (CAPS)

Cryopyrin Associated Periodic Syndrome

France
Handok Inc.

Terminated

HL2351 CAPS Phase II Study

Cryopyrin-Associated Periodic Syndromes (CAPS)

Korea, Republic of
Novartis Pharmaceuticals

Completed

The Safety and Efficacy of Canakinumab in Patients Aged 4 Years or Older Diagnosed With Cryopyrin-associated Periodic Syndromes (CAPS) in Canada

Cryopyrin Associated Periodic Syndrome

Canada
Vifor Pharma, Inc.

Recruiting

Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

Hyperkalemia

United States, Israel
University of Aleppo

Recruiting

Levalbuterol Compared to Albuterol Regarding Cardiac Side Effects and Potassium Lowering Effects.

Hyperkalemia

Syrian Arab Republic
Portsmouth Hospitals NHS Trust
Vifor Pharma

Recruiting

IMpact of hyPeRkalaemia on thErapy With Renin angiotenSin aldoSterone System Inhibitors (IMPRESS)

Hyperkalemia

United Kingdom
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Completed

The Safety and Tolerability of WS016 in Healthy Chinese Volunteers

Hyperkalemia

China
AstraZeneca

Completed

A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 (ENERGIZE)

Hyperkalemia

United States, Russian Federation, Italy, Denmark
ZS Pharma, Inc.

Completed

Safety & Efficacy of Zirconium Silicate in Mild to Moderate Hyperkalemia

Hyperkalemia

United States, Australia
The University of Texas Health Science Center,...
Memorial Hermann Hospital

Completed

Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns (PS)

Hyperkalemia

United States
Michael Frass

Completed

Homeopathic Treatment of Children Suffering From PFAPA (HOMPFAPA)

Periodic Fever Syndrome

Austria
Aclaris Therapeutics, Inc.

Terminated

Study of ATI-450 in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS)

Cryopyrin-Associated Periodic Syndrome

United States
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Nebulized Salbutamol Facilitate Management of Hyperkalemia Postreperfusion During Liver Transplantation

Liver Transplantation
NephroNet, Inc.
AstraZeneca

Recruiting

A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia (ADAPT)

Hyperkalemia

United States
Oslo University Hospital

Completed

Effects of Patiromer on Pharmacokinetics of Immunosuppresive Drugs in Renal Transplant Recipients (TACPAT)

Hyperkalemia | Kidney Transplant

Norway
The Rogosin Institute
Weill Medical College of Cornell University

Completed

Pharmacokinetic Study of Tacrolimus and Mycophenolate Mofetil in Kidney Transplant Recipients With Hyperkalemia Receiving Patiromer

Hyperkalemia | Kidney Transplant

United States
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Recruiting

A Study to Evaluate the Safety and Efficacy of WS016 in Patients With Hyperkalemia.

Hyperkalemia

China
Alexandria University

Recruiting

SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients

Hyperkalemia

Egypt
Zeria Pharmaceutical

Completed

A Comparative Study of ZG-801 and Placebo in Patients With Hyperkalemia

Hyperkalemia

Japan
AstraZeneca

Completed

Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects (DIALIZE China)

Hyperkalemia

China
AstraZeneca

Completed

A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia. (HARMONIZE Asia)

Hyperkalemia

China
Ardelyx

Completed

A Study Evaluating the Safety and Efficacy of RDX013 for the Treatment of Hyperkalemia (Redukx)

Hyperkalemia

United States
Relypsa, Inc.

Terminated

An Open-Label, Multiple Dose Study to Evaluate the Pharmacology, Safety, and Tolerability of Patiromer in Participants on Hemodialysis

Hyperkalemia

United States

Clinical Trials on Hyperkalemic Periodic Paralysis

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