Clinical Trials on Hypertension With Abnormal Renal Function

Total 1578 results

Peking University

Completed

A Pilot Trial of Manlikang in Reducing Salt Intake and Blood Pressure Among Patients With Hypertension

Hypertension | Hypertension With Abnormal Renal Function

China
University of Giessen

Completed

Changes in Renal Function and Body Composition in Pulmonary Hypertension

Pulmonary Hypertension | Renal Function Abnormal

Germany
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency

Subjects With Varying Degrees of Renal Insufficiency and | Subjects With Normal Renal Function

United States
Englewood Hospital and Medical Center

Withdrawn

Neuropsychological Testing Using Mobile Devices

Inpatients With Normal Neurological Function

United States
Northwestern University
National Heart, Lung, and Blood Institute (NHLBI); American Society for Transplantation

Withdrawn

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

High Blood Pressure | Liver Transplant | Renal Function Abnormal

United States
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Subjects With Liver Function Injury | Normal Liver Function Subject

China
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Hannover Medical School

Withdrawn

Cardiopulmonary Interactions in Patients With Heart Failure

Heart Failure | Pulmonary Hypertension | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction

Germany
Sanofi

Completed

A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment

Hepatic Function Abnormal

Bulgaria, France
Sanofi

Completed

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Belgium
Sanofi

Terminated

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

Korea, Republic of, Germany
Geisinger Clinic

Completed

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

Abnormal Liver Function

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Sanofi

Completed

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Germany
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
University of Saskatchewan
Canadian Institutes of Health Research (CIHR)

Completed

Synchrotron Imaging of Human Ovaries Ex Situ

Abnormal Female Reproductive Function

Canada
Astellas Pharma Inc

Completed

ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis

Patients With Impaired Renal Function and Haemodialysis

Japan
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Apatinib in Subjects With Impaired Renal Function

Subjects With Impaired Renal Function and Healthy Subjects
Mitsubishi Tanabe Pharma America Inc.

Completed

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Renal Impairment | Normal Renal Function

Germany
Erasme University Hospital

Unknown

Study of Catheter Based Renal Denervation Therapy in Hypertension (DEPART)

Renal Function | Resistant Hypertension | Ambulatory Blood Pressure | Renal Denervation

Belgium
Shanghai 10th People's Hospital

Completed

Compare the Renal Protective Effects of Febuxostat and Benzbromarone

Chronic Kidney Disease | Hyperuricemia | Abnormal Renal Function

China
Shanghai 10th People's Hospital

Unknown

Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients

Chronic Kidney Disease | Hyperuricemia | Abnormal Renal Function

China
Tenax Therapeutics, Inc.

Active, not recruiting

Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients

Heart Failure With Normal Ejection Fraction | Hypertension Pulmonary Secondary Heart Failure | Right Sided Heart Failure With Normal Ejection Fraction

United States
Medical University of Vienna

Completed

Pharmacodynamic Effects of Riociguat in Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (DYNAMIC)

Hypertension, Pulmonary | Heart Failure With Normal Ejection Fraction

Austria
Wageningen University
Top Institute Food and Nutrition

Completed

The Effects of Sodium and Potassium on Blood Pressure, Vascular Function and Renal Function (KaNa)

Hypertension | Blood Pressure | Vascular Function | Renal Function

Netherlands
Medical University of South Carolina

Completed

LYmphangiogenesis FacTors in Heart Failure States (LYFT-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction

United States
Chulalongkorn University

Recruiting

Association Between Renal Reserve Function and Progression of Renal Function to Predict CKD Risk in Thai Elderly

Renal Function Abnormal | Elder

Thailand
University of Leipzig
ReCor Medical, Inc.

Recruiting

Renal Denervation to Treat Heart Failure With Preserved Ejection Fraction (UNLOAD-HFpEF)

Heart Failure With Preserved Ejection Fraction | Hypertension, Renal

Germany
Pulnovo Medical (Wuxi) Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Recruiting

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure (PADN-HF-PH)

Cardiovascular Diseases | Vascular Diseases | Heart Failure | Hypertension | Pulmonary Hypertension | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Heart Failure With Mid Range Ejection Fraction

China
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Vanderbilt University Medical Center

Recruiting

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals (RARE-PAH)

Idiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo | Healthy Individuals With no Cardiopulmonary Disease

United States
Massachusetts General Hospital
Roche Diagnostics

Recruiting

Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure (PREFER-HF)

Cardiovascular Risk Factor | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Heart Failure, Right Sided | Heart Failure With Mid Range Ejection Fraction

United States
RWTH Aachen University

Unknown

Impact of Acute Cerebral Diseases on the Autonomous Nervous System: Progression and Correlation to Therapy and Outcome (Pupillometry)

Cerebral Aneurysm | Pupillary Function, Abnormal

Germany
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

PK Properties Of Gabapentin In Subjects With Impaired Renal Function

Japan
Seoul National University Hospital

Unknown

Evaluation of PK and Biomarkers After UDCA Administrations to Subjects Who Are Overweight and Have Liver Problems

Overweight | Abnormal Liver Function Tests

Korea, Republic of
Tenax Therapeutics, Inc.

Completed

Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF (HELP)

Heart Failure With Normal Ejection Fraction | Heart Failure, Right Sided | Hypertension Pulmonary Secondary

United States
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); Office of Dietary Supplements...

Completed

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP)

Second Hand Smoke | Pulmonary Function; Newborn, Abnormal | Infant Wheeze | In-utero Nicotine

United States
Gladwin, Mark, MD
National Heart, Lung, and Blood Institute (NHLBI); University of Pittsburgh; National...

Withdrawn

Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension

Pulmonary Hypertension | Heart Failure With Normal Ejection Fraction | Pulmonary Heart Disease and Diseases of Pulmonary Circulation

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); Beth Israel Deaconess Medical... and other collaborators

Active, not recruiting

Circulating RNAs in Acute Congestive Heart Failure (CRUCiAL)

Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Acute Congestive Heart Failure

United States
Memorial Hospital of Rhode Island
University of California, San Diego; National Heart, Lung, and Blood Institute... and other collaborators

Unknown

WHISH-2-Prevent Heart Failure

Heart Failure | Physical Activity | Elderly | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Women | Strength Training

United States
Novartis Pharmaceuticals

Completed

Safety and Tolerability and Efficacy of LCZ696 in Japanese Hypertensive Patients With Renal Dysfunction

Hypertension With Renal Dysfunction

Japan
Daiichi Sankyo Co., Ltd.

Completed

Study of CS-3150 in Combination With ARB or ACE Inhibitor in Hypertensive Patients With Moderate Renal Impairment

Hypertension With Moderate Renal Impairment

Japan
CorAssist Cadiovascular Ltd.

Terminated

ImCardia for DHF to Treat Diastolic Heart Failure (DHF) Patient a Pilot Study (ImCardia)

Heart Failure With Normal Ejection Fraction
Martin Angst

Completed

Evaluation of Immune Signaling Networks in Healthy Human Volunteers

Normal Immune Cell Function

United States
Tao Zhang

Unknown

Effects of Dexmedetomidine and Dopamine on Renal Function After Major Surgery

Renal Function

China
Central Hospital, Nancy, France

Not yet recruiting

Urinary Creatinine Excretion Time in the Neonatal Period (C-Rex)

Renal Function

France

Clinical Trials on Hypertension With Abnormal Renal Function

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Papua New Guinea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations