Clinical Trials on Immune Reconstitution Inflammatory Syndrome

Total 11379 results

National Institute of Allergy and Infectious Diseases...

Recruiting

PET Imaging and Lymph Node Assessment of IRIS in People With AIDS

Immune Reconstitution Inflammatory Syndrome

United States
Duke University
GlaxoSmithKline; Kilimanjaro Christian Medical Centre, Tanzania; Kibongoto National...

Completed

Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST) (THIRST)

HIV | Tuberculosis

Tanzania
National Institute of Allergy and Infectious Diseases...

Completed

Immune Reconstitution Syndrome in HIV-Infected Patients Taking Antiretroviral Therapy

Immune Reconstitution Inflammatory Syndrome

United States, Thailand
Instituto Nacional de Ciencias Medicas y Nutricion...
University of Pennsylvania; University of Witwatersrand, South Africa; Case Western... and other collaborators

Unknown

Maraviroc (CCR5) Antagonism to Decrease the Incidence of the Immune Reconstitution Inflammatory Syndrome in HIV-Infected Patients (CADIRIS)

HIV Infections | HIV | Immune Reconstitution Inflammatory Syndrome

Mexico, United States, South Africa
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Hospital Tuebingen; Albert Schweitzer Hospital

Completed

Prediction and Pathogenesis of the Immune Reconstitution Inflammatory Syndrome (IRIS)

Opportunistic Infections | Immune Reconstitution Inflammatory Syndrome

Gabon
University of Cape Town
Imperial College London; Institute of Tropical Medicine, Belgium; European and... and other collaborators

Completed

Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone (Pred-ART)

HIV | Tuberculosis | Immune Reconstitution Inflammatory Syndrome

South Africa
University of Minnesota
Pfizer; Minnesota Medical Foundation

Withdrawn

Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trial

Tuberculosis | Immune Reconstitution Inflammatory Syndrome | HIV-infection/Aids | Immune Reconstitution Syndrome

Thailand
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.

Kaposi Sarcoma | Human Immunodeficiency Virus | Immune Reconstitution Syndrome

Mexico
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pediatric Urgent Start of Highly Active Antiretroviral Treatment (HAART) (PUSH)

Human Immunodeficiency Virus | Immune Reconstitution Inflammatory Syndrome

Kenya
Biogen
Elan Pharmaceuticals

Terminated

Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS) (IRIS)

Leukoencephalopathy, Progressive Multifocal | Immune Reconstitution Inflammatory Syndrome

Germany, United States
Jongmin Lee

Completed

Presepsin as Detective Marker of Sepsis in Immunodeficiency ICU Patients (PREICU)

Sepsis | Immune Deficiency

Korea, Republic of
Shandong Qilu Cell Therapy Engineering Technology...
Shandong Public Health Clinical Center

Recruiting

Mesenchymal Stem Cells for Immune Non-responder Patients With HIV Infection

AIDS Virus | Disorder of Immune Reconstitution

China
Beijing 302 Hospital

Unknown

Safety and Efficacy of Allogenic Adoptive Immune Therapy for Immune Reconstitution in Chronic HIV-1 Infected Patients

Human Immunodeficiency Virus | Disorder of Immune Reconstitution

China
Fu-Sheng Wang

Unknown

Umbilical Cord Mesenchymal Stem Cells for Immune Reconstitution in HIV-infected Patients

Human Immunodeficiency Virus | Disorder of Immune Reconstitution

China
China Medical University Hospital

Recruiting

TCM Constitution, Pattern Types, and Disease Factors in Primary Lung Cancer.

Syndrome | Risk Factors | Body Constitution | Medicine, Chinese Traditional

Taiwan
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
Xiangya Hospital of Central South University

Unknown

Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status

Sepsis | Inflammatory Disorder of Immune System
The University of Queensland
Royal Brisbane and Women's Hospital

Unknown

Exercise in Critically Ill Patients With Sepsis

Sepsis Syndromes

Australia
National Cancer Institute (NCI)

Recruiting

Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS) | KSHV | HHV-8

United States
Cabaletta Bio

Recruiting

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy

Idiopathic Inflammatory Myopathy | Dermatomyositis | Immune-Mediated Necrotizing Myopathy | Anti-Synthetase Syndrome

United States
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Electro-acupuncture at Zusanli, Qihai, and Guanyuan Acupoints Regulate Immune Function in Patients With Sepsis (EAIm-sepsis)

Sepsis | Immune Dysfunction

China
Charles University, Czech Republic

Recruiting

Immune Homeostasis in Sepsis and Septic Shock (IMHOTEP)

Sepsis | Immune Deficiency | Immunologic Paralysis | Immunologic Suppression

Czechia
University of Cologne

Completed

Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial Surgery

Systemic Inflammatory Response Syndrome (SIRS)

Germany
CytoAgents, Inc.
TFS HealthScience

Recruiting

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

Cytokine Release Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Collection of Blood, Bone Marrow, Leukapheresis, and Tissue Biopsy Samples From Patients and Their Family Members for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases Laboratory Research Studies

Idopathic Inflammatory/Autoimmune Syndromes

United States
St Mark's Hospital Foundation

Completed

Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn's Disease Patients

Celiac Disease | Malabsorption Syndromes | Crohn's Disease | Short Bowel Syndrome

United Kingdom
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; Commissariat... and other collaborators

Recruiting

Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis (RECORDS)

Sepsis

France
Mayo Clinic

Completed

The Effects of HIV Protease Inhibitors in Severe Sepsis

Sepsis

United States
Nanjing First Hospital, Nanjing Medical University

Completed

The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis

Sepsis | Enteral Feeding | Immune System Disorder

China
Second Affiliated Hospital, School of Medicine,...

Completed

The Study of NT-proBNP Combined With HS-cTnT in Evaluating the Prognosis of Sepsis

Sepsis

China
Ludwig-Maximilians - University of Munich
City of Munich

Completed

Validation of Progranulin as a Biomarker for Sepsis (PROGRANULIN)

Sepsis

Germany
Université Catholique de Louvain

Terminated

Perioperative Evaluation of Immuno-inflammatory Parameters

Combined Inflammatory and Immunologic Defect

Belgium
Rutgers, The State University of New Jersey

Completed

The Effects of Epinephrine in Endotoxemia in Normal Volunteers (Epi)

Immune System

United States
University Hospital, Limoges

Terminated

Following of Myeloid-derived Suppressor Cells (MDSC) in Severe Sepsis: What Relationship With Systemic Inflammatory Syndrome? (MDSC)

Severe Sepsis | Inflammatory Response Syndrome, Systemic

France
Arkansas Children's Hospital Research Institute
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial) (GRIPIT)

SIRS (Systemic Inflammatory Response Syndrome(

United States
Hellenic Institute for the Study of Sepsis

Completed

A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis (PROVIDE)

Sepsis | Macrophage Activation Syndrome

Greece
Medical University of Gdansk

Completed

Bands in Peripheral Blood After Coronary Artery Bypass Grafting With and Without Cardiopulmonary Bypass

Inflammatory Response Syndrome, Systemic | Granulocyte Immature Forms

Poland
Oxford University Clinical Research Unit, Vietnam
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Recruiting

Anakinra in Dengue With Hyperinflammation ( AnaDen )

Cytokine Storm | Dengue | Severe Dengue | Macrophage Activation Syndrome | Anakinra | Dengue With Warning Signs | Anti-inflammatory Agents | Hyperinflammatory Syndrome | Immuno-modulation

Vietnam
Chinese PLA General Hospital

Completed

Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients

Sepsis | SIRS(Systemic Inflammatory Response Syndrome)

China
Chinese PLA General Hospital

Unknown

The Changes of CD4+T Lymphocyte Subsets in Septic Patients

Sepsis | SIRS(Systemic Inflammatory Response Syndrome)

China
Immunexpress
Johns Hopkins University; Northwell Health; Rush University Medical Center; Intermountain... and other collaborators

Completed

VENUS: Septic Gene Expression Using SeptiCyte (VENUS)

Sepsis | Systemic Inflammatory Response Syndrome (SIRS)

United States
Seattle Children's Hospital
Immunexpress

Completed

Genotypes and Phenotypes in Pediatric SIRS and Sepsis (GAPPSS)

Sepsis | Systemic Inflammatory Response Syndrome (SIRS)

United States
University of Arkansas

Terminated

Near-Continuous, Noninvasive Blood Pressure Monitoring to Improve Outcomes in Pediatric Transport

Pediatric Patients With SIRS (Systemic Inflammatory Response Syndrome)

United States
Shanghai Public Health Clinical Center

Recruiting

Study of MDW Levels Predicting the Development of Sepsis in Hospitalized HIV-infected Patients and Correlation With Prognosis

HIV Infections | Sepsis

China
Suez Canal University

Recruiting

Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis (BIS6)

Sepsis, Severe

China
Radboud University Medical Center
UMC Utrecht; Prothya Biosolutions

Completed

In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II (VECTORII)

Sepsis | Inflammation | Endotoxemia | Innate Immune Response

Netherlands
Iuliu Hatieganu University of Medicine and Pharmacy

Completed

Interventions Meant to Improve the Outcome of Critical Care Patients in the ED

Sepsis Syndrome | Emergency Department | Biomarker

Romania
Germans Trias i Pujol Hospital

Completed

Switching From Protease Inhibitor (PI) to Etravirine in HIV-1 Infected Subjects With Viremia Suppression

HIV

Spain
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Genotypic Tropism Testing In Proviral Dna To Guide CCR5 Antagonist Treatment In Subjects With Undetectable HIV-1 Viremia

HIV

Spain
University of Nottingham

Completed

Effect of Lipopolysaccharide on Skeletal Muscle Functions (LPS)

Sepsis

United Kingdom

Clinical Trials on Immune Reconstitution Inflammatory Syndrome

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