Clinical Trials on LVOTO - Left Ventricular Outflow Tract Obstruction

Total 951 results

National Heart, Lung, and Blood Institute (NHLBI)

Completed

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

Mitral Valve Failure

United States
St. Antonius Hospital

Recruiting

Reverse Remodeling After PTSMA in Severe But Asymptomatic LVOT Obstruction (RASTA)

HOCM, Hypertrophic Obstructive Cardiomyopathy | LVOTO - Left Ventricular Outflow Tract Obstruction | Remodeling, Ventricular

Netherlands
Medical University of Warsaw

Recruiting

Polish Registry of Common Carotid Artery Access for TAVI (POL-CAROTID)

Aortic Valve Stenosis | Ventricular Outflow Obstruction, Left

Poland
Medical University of Warsaw

Recruiting

Polish Transcatheter Aortic Valve-in-Valve Implantation (ViV-TAVI) Registry

Aortic Valve Stenosis | Aortic Valve Insufficiency | Ventricular Outflow Obstruction, Left

Poland
Oslo University Hospital

Completed

Better Patient Selection to Transcatheter Aortic Valve Implantation

Myocardial Fibrosis | Aortic Valve Stenosis | Left Ventricular Dysfunction

Norway
Universitätsklinikum Hamburg-Eppendorf

Unknown

Non-invasive Blood Pressure and Cardiac Output Measurement by Using Applanation Tonometry

Atrial Fibrillation | Aortic Valve Stenosis | Left Ventricular Failure | Left Ventricular Impaired Function

Germany
University of Edinburgh

Unknown

Mechanism of Decompensation Evaluation - Aortic Stenosis (MODE-AS)

Myocardial Fibrosis | Aortic Stenosis | Left Ventricular Hypertrophy

United Kingdom
Odense University Hospital

Unknown

Effect of Angiotensin II Receptor Blockers (ARB) on Left Ventricular Reverse Remodelling After Aortic Valve Replacement in Severe Valvular Aortic Stenosis

Atrial Fibrillation | Aortic Valve Stenosis | Left Ventricular Hypertrophy

Denmark
Hanmi Pharmaceutical Company Limited

Completed

Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease

Hypertension | Aortic Stenosis | Aortic Regurgitation | Left Ventricular Hypertrophy | LVM

Korea, Republic of
University of Aarhus
Aarhus University Hospital

Recruiting

Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis Intervention (DAPAS)

Aortic Stenosis | Left Ventricle Hypertrophied

Denmark
Central Hospital, Nancy, France

Unknown

Ventriculo-arterial Coupling Modification Evaluated by PRAM During TAVI Procedure (PRAM-TAVI)

Aortic Valve Stenosis | Ventricular Dysfunction, Left

France
MyoKardia, Inc.

Completed

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction (PIONEER-HCM)

Cardiomyopathy, Hypertrophic Obstructive | Left Ventricular Outflow Tract Obstruction

United States
Massachusetts General Hospital

Recruiting

Imaging Histone Deacetylase in the Heart

Diabetes | Aortic Valve Stenosis | Heart Failure With Normal Ejection Fraction | Left Ventricular Hypertrophy

United States
University of Edinburgh
Sir Jules Thorn Charitable Trust

Active, not recruiting

Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS (EVoLVeD)

Aortic Valve Stenosis | Hypertrophy, Left Ventricular

United Kingdom
University Hospital, Bonn

Completed

Transcatheter Aortic Valve Implantation Without Predilation (SIMPLIFy TAVI)

Aortic Stenosis | Left Ventricular Function Systolic Dysfunction | High-risk Patients | Transcatheter Aortic Valve Implantation

Germany
University of Monastir

Completed

STI Combined to Valsalva Maneuver for the Diagnosis of Left Ventricular Dysfunction in COPD Exacerbations (STICOPD)

Obstructive Chronic Bronchitis With Acute Exacerbation

Tunisia
Venus MedTech (HangZhou) Inc.
TheraGenesis GmbH of Oppenheim, Germany; IQVIA MedTech BV of Antwerp, Belgium

Not yet recruiting

Observational Study of Venus P-Valve (Registry)

Right Ventricular Outflow Tract Dysfunction
European Association of Cardiovascular Imaging

Unknown

Prognostic Impact of Myocardial Longitudinal Strain in Asymptomatic Aortic Stenosis: a Meta-Analysis

Aortic Valve Stenosis | Left Ventricular Function | Asymptomatic Conditions

France
Medical University of Vienna

Completed

Glutamate and Diastolic Function in Patients Undergoing Aortic Valve Repair

Myocardial Ischemia | Aortic Stenosis | Cardiopulmonary Bypass | Hypertrophy, Left Ventricular

Austria
Boston University
Gilead Sciences

Completed

Study of Ranolazine in the Treatment of Pulmonary Hypertension Associated With Diastolic Left Ventricular Dysfunction

Pulmonary Hypertension | Diastolic Left Ventricular Dysfunction

United States
Medtronic Cardiovascular

Completed

Melody® Transcatheter Pulmonary Valve Post-Approval Study

Dysfunctional Right Ventricular Outflow Tract (RVOT) Conduit

United States
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study

Aortic Valve Stenosis | Hypertrophic Cardiomyopathy | Mitral Valve Disease | Left Ventricular Septal Hypertrophy

United States
University Hospital, Limoges

Withdrawn

Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized mulTi-cEntric Double-blind Phase II Study (ARISTOTE)

Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement | Hypertrophy, Left Ventricular | Angiotensin Receptor Antagonists | Heart Valve Prosthesis Implantation | Valsartan

France
GE Healthcare
Oregon Health and Science University

Completed

A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System

Heart Valve Diseases | Pulmonary Hypertension | Right Ventricular Dysfunction | Left Ventricular Dysfunction

United States
Institut für Pharmakologie und Präventive Medizin

Completed

Pulmonic SAPIEN S3™ THV Registry (PulmonicS3)

Pulmonary Valve Malfunction | Right Ventricular Outflow Tract (RVOT) Dysfunction

Switzerland, Germany, Canada
Actelion

Completed

Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction (MELODY-1)

Pulmonary Hypertension

United States, Austria, Belgium, Canada, Czechia, France, Germany, Israel, Italy, Spain, Switzerland
Assistance Publique Hopitaux De Marseille

Completed

Right and Left Ventricle Remodeling Predictors After Pulmonary Valve Replacement in Patients With Repaired Tetralogy of Fallot

Tetralogy of Fallot With Pulmonary Stenosis

France
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)

Pulmonary Disease | Heart Failure With Preserved Ejection Fraction | Left Ventricular Hypertrophy/Hypertension

United States
Assiut University

Not yet recruiting

Role of Echocardiography in the Assessment of Right Ventricular Function in the Pediatric Population With Valvular Pulmonary Stenosis.

Right Ventricular Dysfunction
Tanta University

Completed

Left Ventricular Diastolic Dysfunction as a Predictor of Weaning Failure From Mechanical Ventilation

Mechanical Ventilation Complication | Weaning Failure | Diaphragmatic Disorder | Left Ventricular Diastolic Dysfunction

Egypt
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Medico-economic Evaluation of a Non-chirurgical Pulmonary Valve Replacement (REVALV) (REVALV)

Dysfunction of the Prosthetic Conduct | Lesions of the Right Ventricular Outflow Tract

France
Cytokinetics

Completed

Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)

Heart Failure

United States, Canada, Germany, Italy, Netherlands, Belgium, France, Czechia, Australia, Russian Federation, Hungary, Poland, Bulgaria, Slovakia, United Kingdom, Finland, Greece, Lithuania, Norway
Montreal Heart Institute

Recruiting

Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI (COME-TAVI)

Aortic Valve Stenosis | Left Bundle-Branch Block

Canada
Azienda Ospedaliera, Universitaria Policlinico...
Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy

Unknown

Stenting of Renal Artery Stenosis in Coronary Artery Disease Study (RASCAD)

Renal Artery Stenosis | Left Ventricular Hypertrophy

Italy
Sahlgrenska University Hospital, Sweden

Completed

Cardiac Dysfunction in Critically Ill Patients With COVID-19 (CARDYCOVID)

Covid19 | Pulmonary Hypertension | Right Ventricular Dysfunction | Left Ventricular Dysfunction

Sweden
The University of Hong Kong

Unknown

Opportunistic Screening for Asymptomatic Left Ventricular Dysfunction in Coronavirus Disease 2019 (COVID19) Survivors

COVID-19

Hong Kong
Poznan University of Medical Sciences

Completed

Reduction of Left Ventricular Hypertrophy After Eplerenone Therapy

Obstructive Sleep Apnea | Left Ventricular Hypertrophy | Hypertension,Essential
University of Michigan

Completed

Hemodynamic Comparison of Tissue Aortic Valves

Aortic Valve Stenosis

United States
Lisa Gundestrup

Not yet recruiting

Aortic Stenosis Associated Left Ventricular Remodeling - An Investigation of Genetic and Gender Specific Differences in 170 Patients Undergoing Aortic Valve Replacement Surgery (SALVAGE)

Aortic Valve Stenosis
University Hospital, Rouen

Active, not recruiting

Aortic Stenosis: Determinants and Prognostic Value of Preoperative Left Ventricular Remodeling After Valvular Replacement

Aortic Valve Stenosis

France
Queen Silvia Children's Hospital, Gothenburg, Sweden
Sahlgrenska University Hospital, Sweden; Swedish Heart Lung Foundation

Recruiting

Effect of Fetal Aortic Valvuloplasty on Outcomes (FASSprosp)

Aortic Valve Stenosis | Congenital Heart Disease | Hypoplastic Left Heart Syndrome | Fetal Cardiac Disorder

United States, Austria, Canada, Finland, Germany, Poland, Spain, Sweden
Wake Forest University Health Sciences
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) (PHRASE)

Kidney Diseases | Hypertension | Pediatric Obesity | Proteinuria | Albuminuria | Kidney Injury | Blood Pressure Disorders | Autonomic Dysfunction | Pediatric Kidney Disease | Left Ventricular Dysfunction | Left Ventricular Hypertrophy | Kidney Dysfunction | Autonomic Imbalance | Left Ventricular Diastolic Dysfunction and other conditions

United States
University Hospital, Strasbourg, France

Unknown

Effects of High Dose Atorvastatin in Patients With Surgical Aortic Stenosis

Aortic Valve Stenosis | Ventricular Hypertrophy

France
Lahey Clinic
Tufts Medical Center

Withdrawn

Ventricular Remodeling In Patients With Aortic Stenosis Assessed Echocardiography

Aortic Stenosis

United States
Sahajanand Medical Technologies Limited
Qmed Consulting A/S

Not yet recruiting

Hydra Single-centre Experience - Copenhagen, Denmark

Aortic Valve Stenosis

Denmark
Fundación EPIC

Recruiting

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation (FAST TRACK)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases

Spain
Ole De Backer

Recruiting

Re-hospitalisation After Transcatheter Aortic Valve Implantation (HOSPITAVI)

Aortic Valve Stenosis | Aortic Valve Disease

Denmark
Guilherme Attizzani, MD

Recruiting

MRI in Transcatheter Aortic Valve Replacement Patients (MRI in TAVR)

Aortic Valve Stenosis

United States
Leipzig Heart Science gGmbH
Heart Center Leipzig - University Hospital

Recruiting

RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation (DOUBLE-CHOICE)

Aortic Valve Stenosis

Germany
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Hamburg AoRtic Valve cOhoRt (HARbOR)

Aortic Valve Stenosis

Germany

Clinical Trials on LVOTO - Left Ventricular Outflow Tract Obstruction

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