Clinical Trials on Lipodystrophy

Total 170 results

University of Texas Southwestern Medical Center
Takeda Pharmaceuticals North America, Inc.

Completed

HIV Acquired Lipodystrophy (HAL) Classification, Measurement and Fat Response to Thiazolidinedione (TZD) (Pioglitazone) (HAL)

HIV Infections

United States
University of Texas Southwestern Medical Center
Amylin Pharmaceuticals, LLC.

Completed

Therapeutic Approaches to HAART-Induced Lipodystrophy

HIV Infections | Lipodystrophy

United States
Theratechnologies

Completed

TH9507 in Patients With HIV-Associated Lipodystrophy

HIV Infections | Lipodystrophy

United States, Canada
University of California, Los Angeles
University Health Network, Toronto; Merck Sharp & Dohme LLC; Tufts University; Vanderbilt... and other collaborators

Completed

Raltegravir Therapy for Women With HIV and Fat Accumulation

HIV Infections | Lipodystrophy

United States, Canada
National Institute of Diabetes and Digestive and...

Completed

A Study to Determine How and Why HIV-Infected Subjects on Anti-viral Treatment Develop Lipodystrophy

HIV Infections | Lipodystrophy

United States
Hvidovre University Hospital
Pfizer

Completed

The Effect of Low-Dose Human Growth Hormone Therapy in HIV Infected Patients

HIV Infections | Lipodystrophy

Denmark
National Institute of Diabetes and Digestive and...

Completed

Leptin to Treat Lipodystrophy

Lipodystrophy

United States
Grace McComsey

Recruiting

The Cleveland Cardiometabolic Cohort

HIV | Lipodystrophy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adults

Metabolic Diseases | HIV Infections | Nutrition Disorders | Lipodystrophy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Metabolic Diseases | HIV Infections | Nutrition Disorders | Lipodystrophy

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs

HIV Infections | Lipodystrophy | HIV Seronegativity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in a Single Patient With Partial Lipodystrophy

Obesity | Hypertriglyceridemia

United States
Recros Medica, Inc.

Completed

CONFORM: Rotational Fractional Resection for Submental Contouring

Lipodystrophy | Skin Laxity

United States
University of Texas Southwestern Medical Center
FDA Office of Orphan Products Development

Completed

Cholic Acid for Hepatic Steatosis in Lipodystrophy

Hepatic Steatosis

United States
Kirby Institute
National Heart, Lung, and Blood Institute (NHLBI); St Vincent's Hospital, Sydney

Completed

HIV Infection And Metabolic Abnormalities Protocol 1 (HAMA001)

Cardiovascular Disease | HIV-Associated Lipodystrophy Syndrome

Australia
Eli Lilly and Company

Active, not recruiting

A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS

Aicardi Goutieres Syndrome | Nakajo-Nishimura Syndrome | Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature Syndrome | STING-Associated Vasculopathy With Onset in Infancy

Japan
National Institute of Allergy and Infectious Diseases...

Completed

Changing to Nonprotease Inhibitor Treatment to Improve Side Effects

HIV Infections | Lipodystrophy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Perceived Changes in Body Build and Image in Patients Who Are Now Taking or Recently Have Stopped Taking Anti-HIV Drugs

HIV Infections | Lipodystrophy

United States
Alaa Hassan M. Elhawary

Unknown

Hemoglobin Level, Coagulopathy Profile and Electrolyte Balance

Obesity | Lipodystrophy

Egypt
Jared Jagdeo, MD, MS
Allergan; VA Northern California Health Care System; East Bay Institute for Research...

Completed

Voluma Filler Agent For The Treatment of HIV-associated Facial Lipoatrophy

HIV Facial Lipoatrophy

United States
Dermatology Cosmetic Laser Medical Associates of...
Sanofi

Withdrawn

Clinical Trial to Determine the Efficacy of Sculptra™ Dermal Filler for the Correction of Contour Deformities Caused by Lipoatrophy

Emaciation | Lipodystrophy

United States
EMD Serono

Completed

Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients

HIV Infections | Lipodystrophy

United States, Canada
National Institute of Diabetes and Digestive and...

Completed

Leptin to Treat Lipodystrophy

Lipodystrophy

United States
Assistance Publique - Hôpitaux de Paris

Completed

Polyacrylamide Hydrogel Injection in HIV-related Lipoatrophy (LIPOPHILL)

HIV Infection | Antiretroviral Side Effects | Lipodystrophy Syndrome Related to HIV Infection

France
Croma-Pharma GmbH

Completed

Safety and Performance of Princess® VOLUME for the Treatment of Facial Lipoatrophy, Asymmetry or Scars (FLASH2)

Facial Lipoatrophy | Morphological Asymmetry of the Face | Debilitating Scars

Austria
Croma-Pharma GmbH

Completed

Safety and Performance of Princess® FILLER for the Treatment of Facial Lipoatrophy, Asymmetry or Scars (FLASH 1)

Facial Lipoatrophy | Morphological Asymmetry of the Face | Debilitating Scars

Austria
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids

HIV Infections | Lipodystrophy

United States, Puerto Rico
Bristol-Myers Squibb

Completed

An Open-Label Treatment Protocol to Provide Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertriglyceridemia Associated With Lipodystrophy

Lipodystrophy

United States
Kobe University
Boehringer Ingelheim

Active, not recruiting

A Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance (EMPIRE-01)

Insulin Resistance - Type A | Insulin Resistance - Type B | Lipoatrophic Diabetes Mellitus | Insulin Resistance Syndrome

Japan
Weill Medical College of Cornell University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance

HIV Infections | Insulin Resistance | Body Weight Changes | Metabolic Syndrome X | HIV-Associated Lipodystrophy Syndrome

United States
Thomas Benfield

Recruiting

Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil (AVERTAS-2)

HIV Infections | Obesity | Renal Insufficiency | Osteoporosis | Hiv | Weight Gain | HIV Lipodystrophy

Denmark
Gerald Pierone, Jr. M.D.
Suneva Medical, Inc.

Completed

Artefill for the Treatment of HIV-associated Facial Lipoatrophy

HIV-facial Lipoatrophy

United States
Bausch Health Americas, Inc.

Completed

Facial Lipoatrophy Correction Experience With SCULPTRA ("FACES" Study) (FACES)

Facial Lipoatrophy

United States
Indústria Brasileira Equipamentos Médicos - IBRAMED

Completed

Shock Waves for Treatment of Gynoid Lipodystrophy and Localized Fat (ESWT)

Cellulitis | Adiposity | Lipodystrophy

Brazil
Kobe University
Boehringer Ingelheim

Active, not recruiting

A Extension Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance ( EMPIRE-02 ) (EMPIRE-02)

Insulin Resistance - Type A | Insulin Resistance - Type B | Lipoatrophic Diabetes Mellitus | Insulin Resistance Syndrome

Japan
Indústria Brasileira Equipamentos Médicos - IBRAMED

Unknown

Motorized Mechanical Massage Associated With Cosmetics in Improving Body Contour and Appearance of Gynoid Lipodystrophy

Cellulitis of Leg

Brazil
Asociacion para el Estudio de las Enfermedades...

Completed

Prevalence of Lipodystrophy Syndrome and Its Role as Cause of Metabolic Disturbances (METALIP)

Metabolic Syndrome | Lipodystrophy

Spain
Eunice Kennedy Shriver National Institute of Child...

Completed

Metabolism and Body Shape of Healthy Children and Children With Chronic Infections

HIV Infections | Healthy | Hyperlipidemia | Lipodystrophy

United States
Thomas Benfield

Recruiting

Changes in Weight, Body Composition and Cardiac Risk After Discontinuing Abacavir Treatment in HIV-infected Individuals (AVERTAS-1)

Cardiovascular Diseases | HIV Infections | Hiv | Weight Change, Body | HIV Lipodystrophy | HIV Cardiomyopathy

Denmark
National Institute of Diabetes and Digestive and...

Completed

Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome

HIV Infections | Insulin Resistance | Lipodystrophy

United States
Kinderkrankenhaus auf der Bult
Sanofi

Completed

Beneficial Effect of Insulin Glulisine by Lipoatrophy and Type 1 Diabetes (LAS) (LAS)

Type 1 Diabetes | Lipoatrophy
University of Texas Southwestern Medical Center
Takeda; National Institutes of Health (NIH); Amylin Pharmaceuticals, LLC.

Completed

Novel Therapies for Metabolic Complications of Lipodystrophies

Diabetes | Insulin Resistance | Hypertriglyceridemia | Hepatic Steatosis

United States
Eli Lilly and Company

No longer available

Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes

Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE) | Juvenile Dermatomyositis (JDM) | Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI) | Aicardi-Goutières Syndrome (AGS)

United States, United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities

HIV Infections | Hyperinsulinemia | Lipodystrophy

United States
University of California, San Diego

Completed

Aramchol for HIV-associated Nonalcoholic Fatty Liver Disease and Lipodystrophy (ARRIVE)

HIV | Nonalcoholic Fatty Liver Disease

United States
University Hospital, Lille

Completed

Adipocyte, Insulin-resistance and Immunity : Evaluation of Interleukin-7 in Lipodystrophy, Diabetes and Obesity (IL-7norm)

Obesity | Type 2 Diabetes | Lipodystrophy

France
National Institute of Allergy and Infectious Diseases...

Completed

Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients

HIV Infections | Lipodystrophy | Wasting Disease

United States
Federico II University
University of Pisa; University of Roma La Sapienza; Università degli Studi del... and other collaborators

Recruiting

Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE" (SIDERALE2020)

Infections | Obesity | Lipodystrophy | Obesity Associated Disorder | Type2diabetes

Italy
University of Michigan
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy

Nonalcoholic Steatohepatitis | Lipodystrophy | Fatty Liver Disease, Nonalcoholic

United States
Hospital Civil de Guadalajara

Not yet recruiting

Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in PLWH. (BERMESyH)

Metabolic Syndrome | Dyslipidemias | Glucose Intolerance | HIV-1-infection | Lipodystrophy | Lipoatrophy

Clinical Trials on Lipodystrophy

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