Clinical Trials on Localized Osteosarcoma

Total 885 results

Children's Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | Unresectable Osteosarcoma | Resectable Osteosarcoma
Children's Oncology Group
National Cancer Institute (NCI); University College, London; Medical Research...

Completed

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma (EURAMOS-1)

Metastatic Osteosarcoma | Localized Osteosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Blood Samples From Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma | Osteoblastic Osteosarcoma

United States
National Cancer Institute (NCI)

Suspended

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | High Grade Osteosarcoma | Secondary Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Italian Sarcoma Group
Associazione Italiana Ematologia Oncologia Pediatrica

Recruiting

Observational Study in Localized Osteosarcoma (ISG Os2Oss)

Localized Osteosarcoma

Italy
Istituto Ortopedico Rizzoli

Recruiting

Tumor Microenvironment in Patients With Localized Osteosarcoma Treated With Mifamurtide: a Translational Study (Micros)

Localized Osteosarcoma

Italy
University Hospital, Ghent

Completed

A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy

Debilitating Fibrosing Skin Disorders (Localised Scleroderma, Eosinophilic Fasciitis)

Belgium
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children

Osteosarcoma | Localised High Grade Osteosarcoma of the Limbs

France
University Hospital, Strasbourg, France

Completed

Genetic Characterisation of High-grade Paediatric Osteosarcomas

Paediatric Osteosarcomas

France
Klinikum Stuttgart
Klinikum Kassel GmbH (COSS-Biobank)

Not yet recruiting

Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas (COSS-Registry)

Osteosarcoma | High Grade Sarcoma | Recurrent Osteosarcoma | Bone Sarcoma | Undifferentiated Pleomorphic Sarcoma | Bone Tumor | Extraskeletal Osteosarcoma | Osseous Sarcoma | Parosteal Osteosarcoma | Osteoblastic Osteosarcoma | Chondroblastic Osteosarcoma | Fibroblastic Osteosarcoma | Conventional Osteosarcoma | Conventional... and other conditions
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma

United States, Canada, Puerto Rico
M.D. Anderson Cancer Center

Recruiting

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

Recurrent Osteosarcoma | Refractory Osteosarcoma | Metastatic Osteosarcoma | Unresectable Osteosarcoma | Locally Advanced Osteosarcoma

United States
Northwestern University

Terminated

Molecular Effects of Topical Calcipotriene on Morphea

Morphea | Localized Scleroderma

United States
UNICANCER

Recruiting

A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas (REGOBONE)

Chondrosarcomas | Ewing Sarcomas | Osteosarcomas | Chondroma | CIC-Rearranged Sarcoma

France
University Children's Hospital, Zurich

Completed

Genetic Variants in Linear Localized Scleroderma

Morphea

Switzerland
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma

Recurrent Ewing Sarcoma | Recurrent Osteosarcoma | Stage III Osteosarcoma AJCC v7 | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma | Metastatic Ewing Sarcoma | Unresectable Ewing Sarcoma | Unresectable Osteosarcoma

France
Sarcoma Alliance for Research through Collaboration

Active, not recruiting

SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma

Osteosarcoma | Osteosarcoma Recurrent | Osteosarcoma Metastatic | Osteosarcoma in Children

United States
University of Cologne

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Dupilumab in Localized Scleroderma (DupiMorph)

Localized Scleroderma

Germany
Cairo University

Unknown

Fractional Carbon Dioxide Laser Versus UVA 1 in Treatment of Localized Scleroderma

Localized Scleroderma

Egypt
Tigenix S.A.U.

Completed

Intralymphatic eASC Administration in Healthy Volunteers

Localized Adverse Reaction to Administration of Drug

Spain
Castle Creek Biosciences, LLC.

Terminated

A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)

Scleroderma, Localized | Morphea | Scleroderma

United States
Istituto Ortopedico Rizzoli

Completed

an Istitution Experience on Parosteal OsTeosarcoma

Parosteal Osteosarcoma

Italy
Italian Sarcoma Group

Completed

Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma (SERIO)

Metastatic Osteosarcoma | Relapsed Osteosarcoma

Italy
Azienda Ospedaliera Ospedale Infantile Regina Margherita...

Completed

Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma

Osteosarcoma Recurrent | Osteosarcoma Metastatic

Italy
Ipsen

Not yet recruiting

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma (CabOSTar)

Osteosarcoma | Osteosarcoma in Children | Osteosarcoma in Adolescents and Young Adults
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma

United States
Dana-Farber Cancer Institute

Completed

Cabozantinib With Topotecan-Cyclophosphamide

Refractory Ewing Sarcoma | Refractory Osteosarcoma | Relapsed Ewing Sarcoma | Relapsed Osteosarcoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma (DOSa)

Recurrent Osteosarcoma | Refractory Osteosarcoma | Metastatic Osteosarcoma | Metastatic Angiosarcoma | Recurrent Dedifferentiated Liposarcoma | Metastatic Dedifferentiated Liposarcoma | Recurrent Angiosarcoma | Refractory Dedifferentiated Liposarcoma

United States
National Cancer Institute (NCI)

Completed

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Metastatic Malignant Neoplasm in the Lung

United States, Canada, Puerto Rico, Australia, New Zealand
Cutera Inc.

Terminated

Thigh Circumference Reduction Study

Reduction of Localized Excess Fat

United States
Italian Sarcoma Group

Terminated

Phase II Trial for the Treatment of Relapsed Osteosarcoma (OsteoREC2015)

OSTEOSARCOMA

Italy
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Active, not recruiting

Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma

Sarcoma | Osteosarcoma | Osteosarcoma Recurrent | Osteosarcoma in Children

United States
Université de Reims Champagne-Ardenne

Recruiting

Neutrophils in Bone Sarcomas (TANOs)

Osteosarcoma, Chondrosarcoma

France
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Osteosarcoma | Refractory Osteosarcoma

United States
National Cancer Institute (NCI)

Completed

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Metastatic Osteosarcoma

United States
Sidnei Epelman

Unknown

Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma

Refractory or Relapsed Osteosarcoma

Brazil
CrystalGenomics, Inc.

Completed

Phase III Study of CG100649 in Osteoarthritis Patients

Localized Primary Osteoarthritis of Hip | Localized Primary Osteoarthritis of Knee

Korea, Republic of
Lee's Pharmaceutical Limited

Not yet recruiting

Study of ZKAB001 for Maintenance Therapy in Patients With High-grade Osteosarcoma After Adjuvant Chemotherapy

High-grade Osteosarcoma
Peking University People's Hospital

Recruiting

Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum

Osteosarcoma of Pelvis

China
Henan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study.

Osteosarcoma, Advanced

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Jazz Pharmaceuticals

Terminated

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma

Metastatic Osteosarcoma

United States
University of Florida
The V Foundation for Cancer Research

Not yet recruiting

Study of RNA-lipid Particle (RNA-LP) Vaccines for Recurrent Pulmonary Osteosarcoma (OSA)

Pulmonary Osteosarcoma
Azienda Ospedaliera Ospedale Infantile Regina Margherita...

Completed

An Analysis of the Efficacy of High Dose Isofosfamide Through Elastomer

Osteosarcoma Recurrent

Italy
George Clinical Pty Ltd
Novartis

Terminated

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

Osteosarcoma | Metastatic Osteosarcoma

United States
University Hospital, Ghent

Completed

Infiltration of the Vestibulum Vaginae With Botulin Toxin in Patients With Localized Provoked Vulvodynia (VVS-01)

Localized Provoked Vulvodynia

Belgium
InSightec

Unknown

Focal MR-Guided Focused Ultrasound Treatment of Localized Intermediate Risk Prostate Lesions

Localized Intermediate Risk Prostate Lesions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand

Clinical Trials on Localized Osteosarcoma

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