Clinical Trials on MSI-H Mutation Tumor
Total 258 results
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Yonsei UniversityMerck KGaA, Darmstadt, GermanyActive, not recruitingPD-L1 Positive Mutation Tumor | EBV Positive Mutation Tumor | MSI-H Mutation Tumor | POLE/POLD1 Mutation TumorKorea, Republic of
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Sidney Kimmel Comprehensive Cancer Center at Johns...Bristol-Myers Squibb; National Cancer Institute (NCI)RecruitingRefractory MSI - H Solid Tumors Prior of PD-(L) 1 Therapy | MSI-H TumorsUnited States
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Shanghai Henlius BiotechRecruiting
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AkesoAkeso Pharmaceuticals, Inc.TerminatedMSI-H/dMMR Solid TumorChina
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BeiGeneRecruitingMSI-H/dMMR Solid TumorsChina
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Peking University Cancer Hospital & InstituteRecruiting
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Chia Tai Tianqing Pharmaceutical Group Co., Ltd.UnknownMSI-H or dMMR Advanced Solid TumorsChina
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Sidney Kimmel Comprehensive Cancer Center at Johns...Merck Sharp & Dohme LLCActive, not recruitingHigh Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)United States
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Servier Bio-Innovation LLCMerck Sharp & Dohme LLC; Institut de Recherches Internationales ServierNot yet recruitingMSI-H/dMMR Gastroesophageal-junction Cancer | MSI-H/dMMR Gastric Cancer
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University of UtahElevar TherapeuticsTerminatedUrothelial Carcinoma | Advanced Malignancies | Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma | MSI-H or dMMR Solid TumorsUnited States
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University Medical Center GroningenRecruitingMelanoma | Head and Neck Neoplasms | MSI-H CancerNetherlands
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsChina
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Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States
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MapKure, LLCRecruitingSolid Tumor | B-Raf Mutation-Related TumorsUnited States, Australia
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Fujian Cosunter Pharmaceutical Co. LtdUnknownSolid Tumor | C-Met Mutation-Related TumorsChina
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Eli Lilly and CompanyActive, not recruitingPancreatic Cancer | Solid Tumor | Cutaneous Melanoma | Microsatellite Instability-High (MSI-H) Solid Tumors | Breast Cancer (HR+HER2-)France, Spain, Belgium, Korea, Republic of, United States, Taiwan, Canada
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Turning Point Therapeutics, Inc.TerminatedAdvanced Solid Tumor | Metastatic Solid Tumor | KRAS Mutation-Related TumorsUnited States
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University of California, San FranciscoGlaxoSmithKlineRecruitingMetastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Sidney Kimmel Comprehensive Cancer Center at Johns...Bristol-Myers Squibb; Vanderbilt University; Avon Breast Health Access FundActive, not recruitingMetastatic Solid Tumor | SF3B1 Gene Mutation | Spliceosome Mutation | U2AF1 Gene Mutation | SRSF2 Gene MutationUnited States
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Shen LinNot yet recruitingTo Evaluate the Safety and Effectiveness of Immunotherapy During the Perioperative Treatment Stage in MSI-H Gastrointestinal CancerChina
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Faeth TherapeuticsActive, not recruitingAdvanced Solid Tumor | PIK3CA Mutation | PTEN Loss of Function MutationUnited States
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Centre Leon BerardAgenus Inc.Not yet recruitingGastric Cancer | Metastatic Cancer | Advanced Cancer | MSI-HFrance
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Medicenna Therapeutics, Inc.Merck Sharp & Dohme LLCRecruitingClear Cell Renal Cell Carcinoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Solid Tumor | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Skin Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Primary Peritoneal Cancer | Endometrial Carcinoma and other conditionsUnited States, Australia, Korea, Republic of, Canada
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University of Campania "Luigi Vanvitelli"CompletedMSI-H Colorectal Cancer
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Fudan UniversityNot yet recruitingGastric Cancer | MSI-H | Adjuvant Therapy | PD-1 ImmunotherapyChina
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Korean Cancer Study GroupUnknownMetastatic Solid Tumor | DDR Gene MutationKorea, Republic of
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Ibrahim Halil SahinBayerNot yet recruitingMSI-H Colorectal CancerUnited States
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Federation Francophone de Cancerologie DigestiveRecruitingTumors | POLD1 Gene Mutation | POLE Exonuclease Domain MutationFrance
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Ibrahim Halil SahinGlaxoSmithKlineNot yet recruitingMMR-D/MSI-H Colorectal CancersUnited States
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Tianjin Medical University Cancer Institute and...RecruitingColon Cancer | Immunotherapy | MSI-H | Adjuvant TherapyChina
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Boehringer IngelheimRecruitingSolid Tumor, KRAS MutationUnited States, Taiwan, Japan
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Prisma Health-UpstateIpsenRecruitingSolid Tumor | ARID1A Gene MutationUnited States
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GERCOR - Multidisciplinary Oncology Cooperative...Bristol-Myers SquibbRecruitingColorectal Cancer Metastatic | MSI-H Colorectal CancerFrance
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Royal Marsden NHS Foundation TrustCompletedMRI | BRCA1 Mutation | BRCA2 Mutation | MammographyUnited Kingdom
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Innovent Biologics (Suzhou) Co. Ltd.Recruiting
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BioMed Valley Discoveries, IncTerminatedAdvanced Solid Tumor | MAP2K1 Gene Mutation | BRAF Gene Mutation | MEK Mutation | BRAF Gene Alteration | MEK Alteration | MAP2K1 Gene Alteration | MAP2K2 Gene Mutation | MAP2K2 Gene AlterationUnited States
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Boehringer IngelheimCompletedSolid Tumors, KRAS MutationJapan
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The First Affiliated Hospital of Zhengzhou UniversityNot yet recruitingCapecitabine | MSI-H Colorectal Cancer | Oxaliplatin | Tislelizumab
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Apexigen America, Inc.CompletedMelanoma | Cancer | Head and Neck Cancer | NSCLC | Urothelial Carcinoma | MSI-HUnited States
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Iambic Therapeutics, IncRecruiting
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Children's Oncology GroupNational Cancer Institute (NCI)RecruitingCentral Nervous System Tumor | Somatic Mutation | Pediatric Central Nervous System Tumor | Discordant TwinUnited States
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS MutationSpain, United Kingdom, United States, Belgium
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Shanghai Jiatan Pharmatech Co., LtdCompletedPIK3CA Mutation-Related TumorsChina
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ImmuneOncia Therapeutics Inc.Not yet recruitingA Study of Phase2, IMC-001 In Patients With Metastatic Or Locally Advanced TMB-H Solid Tumor (TMB-H)TMB-H | Histologically or Cytologically Proven Metastatic or Locally Advanced Solid Tumors
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Olivia Newton-John Cancer Research InstituteBristol-Myers SquibbActive, not recruitingNeuroendocrine Tumors | Advanced Biliary Tract Cancer | Female Reproductive System Neoplasm | MSI-H Solid Malignant TumorNew Zealand, Australia
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Tianjin Medical University Cancer Institute and...RecruitingMSI-H Advanced Colorectal CancerChina
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Sun Yat-sen UniversityActive, not recruitingDMMR Colorectal Cancer | MSI-H Colorectal Cancer | Locally Advanced Colorectal CancerChina
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationAustralia
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West China HospitalFirst Affiliated Hospital of Chongqing Medical University; Sichuan Cancer Hospital... and other collaboratorsRecruitingRectal Cancer | Radiotherapy | Anti-PD-1 Antibody | MSI-H | Mmr DeficiencyChina
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BeBetter Med IncXiangya Hospital of Central South UniversityRecruitingAdvanced or Metastatic Solid Tumor | KRAS G12C MutationChina