Clinical Trials on Malformations

Total 1118 results

University of Michigan

Enrolling by invitation

Dynamic MRI and Quantitative MR CSF Flow Studies in Craniovertebral Junction Anomalies

Chiari Malformations
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Identification of Genetic Mutations Involved in Chiari Type I Malformations (ChiariGene)

Chiari Malformation, Type 1

France
Assiut University

Recruiting

Modalities of Surgical Treatment of Chiari Malformation Disease : Clinical Study and Outcomes

Chiari Malformation, Type 1

Egypt
Xuanwu Hospital, Beijing

Recruiting

PFDD Versus PFDRT in Chiari Decompression Surgery

Tonsillectomy | Chiari Malformation Type I

China
University of Illinois at Chicago

Completed

Duragen Versus Duraguard in Chiari Surgery

Chiari Malformation

United States
St. Luke's-Roosevelt Hospital Center

Completed

Safety of Apollo Micro Catheter in Pediatric Patients

Brain Arteriovenous Malformation | Brain Vascular Malformations | Vein of Galen Malformation

United States
Hacettepe University

Recruiting

Investigation of the Effects of Exercise Program in Patients With Chiari Type 1 Malformation

Arnold Chiari Malformation

Turkey
Duke University

Completed

The Genetics of Chiari Type I Malformation

Chiari Type I Malformation

United States
University Hospital, Limoges

Recruiting

Impact of CErebral Endovascular PROcedures on the Systemic Immune responSe Response (PROCESS)

Cerebral Arterio-venous Malformation

France
Central Hospital, Nancy, France
University of Lorraine

Unknown

Postual Control in Pediatric Chiari I Malformation

Pediatric | Chiari I Malformation

France
Venthera, Inc., a BridgeBio company

Terminated

First in Human Trial of Topical VT30 in Pts With Venous/Lymphatic Malformations Assoc With PIK3CA or TEK Gene Mutations

Lymphatic Malformation | Venous Malformation | Venolymphatic Malformation

United States
University Hospital, Bordeaux

Completed

Arnold Chiari Malformation: the Otological Assessment as an Objective Criteria for Surgical Treatment (MCoto)

Arnold-Chiari Malformation, Type 1

France
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Washington University School of Medicine
Patient-Centered Outcomes Research Institute; Mayo Clinic; The University of... and other collaborators

Completed

Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia

Syringomyelia | Arnold-Chiari Malformation, Type 1 | Chiari Malformation Type I | Type I Arnold-Chiari Malformation

United States
National Institute of Neurological Disorders and...

Completed

Genetic Analysis of the Chiari I Malformation

Syringomyelia | Type I Arnold Chiari Malformation

United States, Russian Federation
King's College Hospital NHS Trust
King's College London

Completed

A Review of Surgical Management of Congenital Pulmonary Airway Malformations (CPAM): A Decade of Experience (CPAM)

Congenital Disorders | Pulmonary Arteriovenous Malformation

United Kingdom
University Hospital Erlangen

Completed

Influence of Flat-knitted Compression Stockings Class I and II on Venous Malformations

Vascular Diseases | Vascular Malformations | Venous Malformation | Vascular Malformation Peripheral

Germany
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Development of a Patient-reported Outcome Measure for Chiari Malformation and Syringomyelia (BCS-score)

Syringomyelia | Chiari Malformation

France
Centre hospitalier de l'Université de Montréal...

Active, not recruiting

Transvenous Approach for the Treatment of Cerebral Arteriovenous Malformations (TATAM)

Unruptured Brain Arteriovenous Malformation | Ruptured Brain Arteriovenous Malformation | Arteriovenous Malformations, Cerebral

Canada, France
Rennes University Hospital

Completed

Pregnancy Environment and Newborn Malformations (PENEW)

Congenital Malformation

France
Al-Azhar University

Completed

Treatment of Venous Malformation

Venous Malformation

Egypt
University Hospital, Tours

Completed

suPERficial Slow-flow Vascular malFORMations Treated With sirolimUS (PERFORMUS)

Vascular Malformation

France
USFetus
University of Southern California; Wellington Hospital

Recruiting

Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele

Neural Tube Defects | Myelomeningocele | Spina Bifida | Chiari Malformation

United States
Medical University of South Carolina

Recruiting

Weekly Sirolimus Therapy

Lymphatic Malformation | Venous Malformation

United States
Hospices Civils de Lyon

Not yet recruiting

Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection (3DLP)

Pulmonary Malformation

France
University Hospital, Toulouse

Completed

Electromagnetic Navigation During Ultrasound Guided Foam Sclerotherapy for Venous Malformations (SCLERONAV)

Venous Malformation

France
Suez Canal University

Completed

Complications of Ethanol-amine Oleate Intralesional Sclerotherapy

Venous Malformation

Egypt
Sohag University

Recruiting

Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations

Vascular Malformations | Microcystic Lymphatic Malformation | Combined Vascular Malformation

Egypt
Yonsei University

Completed

Urodynamic Evaluation in Patients With Anorectal Malformation According to Spinal Cord Abnormalities

Anorectal Malformation

Korea, Republic of
Children's Hospital of Fudan University
Second Affiliated Hospital of Wenzhou Medical University; Guangzhou Women and... and other collaborators

Recruiting

Genomic Sequencing and Personalized Treatment for Birth Defects in Neonatal Intensive Care Units

Genetic Disease | Congenital Malformation | Multiple Malformation

China
Oslo University Hospital

Active, not recruiting

Compare Two Different Sclerosing Agents in the Treatment of Venous Malformations

Venous Malformation

Norway
Carmel Medical Center

Unknown

Cohort Prospective Study of Children With Head and Neck Cystic Malformation Who Are Treated With Intracystic OK432 (OK432)

CYSTIC MALFORMATION

Israel
Assiut University

Unknown

Laparoscopically Assisted Anorectal Pull-through Versus Posterior Sagittal Anorectoplasty

Anorectal Malformation
Hospital Israelita Albert Einstein

Completed

Fetoscopic Open Spina Bifida Repair Using the SAFER Technique

Chiari Malformation Type 2 | Myelomeningocele | Meningomyelocele | Open Spina Bifida | Chiari Malformation With Spina Bifida

Brazil
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Neuroradiology Assesses Chiari Malformation's Impact on Airways, Cranial Base, and Sleep Disorders in Children. (CHDSB)

Malformation Brain

Italy
Johns Hopkins University

Recruiting

Patient Reported Outcomes for Vascular Malformations EmbolizatioN (PROVEN)

Vascular Malformations | VM - Vascular Malformation

United States
Centre hospitalier de l'Université de Montréal...
Centre Hospitalier Régional et Universitaire de Brest

Recruiting

Treatment of Brain AVMs (TOBAS) Study (TOBAS)

Arteriovenous Malformations | Unruptured Brain Arteriovenous Malformation | Ruptured Brain Arteriovenous Malformation | AVM | BAVM

France, United States, Canada, Brazil, Chile, Colombia
National Health Service, United Kingdom

Unknown

Assessing the Effects of Air-cooling on Capillary Malformations

Laser | Capillary Malformation | Skin Cooling

United Kingdom
Centre Hospitalier Universitaire Dijon

Recruiting

Evaluation of Rapid First-line Genome Sequencing for Prenatal Diagnosis of Congenital Malformations in Comparison With Chromosomal Microarray and Exome Sequencing (PRENATOMEultra)

Congenital Malformation

France
Orfagen
FDA Office of Orphan Products Development

Completed

Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study.

Congenital Venous Malformation

United States, France
Kent State University
Utah State University; The University of Akron

Active, not recruiting

Examining Different Components of Online Acceptance and Commitment Therapy for People With Chiari Malformation

Chronic Pain | Chiari Malformation

United States
Kent State University
Utah State University; Conquer Chiari

Completed

Online Acceptance and Commitment Therapy for Chronic Pain in Sample of People With Chiari Malformation

Chronic Pain | Chiari Malformation

United States
First Affiliated Hospital, Sun Yat-Sen University

Unknown

Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery

Arteriovenous Malformation

China
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Efficacy and Safety of Anti-angiogenic Therapy With IV Bevacizumab in Patients With Symptomatic Cerebral Arteriovenous Malformations (BevacizuMAV)

Cerebral AV Malformation
Microvention-Terumo, Inc.
ClinSearch

Terminated

PHIL Evaluation in the Endovascular Treatment of Intracranial Cerebral ArterioVenous Malformation (cAVM)

Cerebral AV Malformation

United Kingdom, Spain, Denmark, France, Sweden
Stanford University
Boston Children's Hospital

Recruiting

Trametinib in the Treatment of Complicated Extracranial Arterial Venous Malformation

Arterial Disease | Venous Malformation

United States
Centre Hospitalier Universitaire Dijon
Novartis Pharmaceuticals

Recruiting

Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients With Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP) (SESAM)

Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)

France
St. Joseph's Hospital and Medical Center, Phoenix

Completed

Dural Graft Equivalent Comparison Trial (DECOMPRESS)

Chiari Malformation

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Cerebral Vascular Malformations: From Multimodal Imaging, to Endovascular, Surgical or Combined Treatment

AVM (Arteriovenous Malformation) Intracranial

Italy
Southern Medical University, China

Recruiting

Clinical Study of the Treatment of Chiari Malformation Combined With Type II Skull Base Depression

Chiari Malformation | Basilar Invagination | Atlantoaxial Dislocation

China

Clinical Trials on Malformations

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Medical Conditions

Drug Interventions

CROs by country

CROs in Myanmar

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Rare Diseases

Drug Interventions

Dietary Supplements

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