Clinical Trials on Metabolic Side Effects of Drugs and Substances

Total 11148 results

Albert Einstein College of Medicine

Completed

Studies of Sulfur Metabolism in Humans

Metabolic Side Effects of Drugs

United States
University of Copenhagen
Carlsberg Foundation

Completed

Metabolic Imprints of Alcoholic Beverages (MetAl)

Metabolic Side Effects of Drugs and Substances

Denmark
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Olympic Seafood AS

Completed

Safety and Tolerability of Krill Powder Supplement in Slightly Overweight People With Moderately Elevated Blood Pressure

Adverse Drug Event | Side Effects of Drugs

Finland
Indiana University
National Institute of General Medical Sciences (NIGMS)

Completed

Bupropion Stereoselective Disposition and CYP2D6-mediated Drug Interactions in Healthy Volunteers

Adverse Effect of Drug Therapy Metabolism Medications (Diagnosis)

United States
Walter Reed National Military Medical Center
United States Department of Defense; General Services Administration (GSA)

Active, not recruiting

Reducing Concurrent Opioid-Benzodiazepine Prescriptions

Adverse Drug Effect of Opioids | Adverse Drug Effect of Benzodiazepines

United States
Companion Dx Reference Lab, LLC

Unknown

Utility of PharmacoGenomics for Reducing Adverse Drug Effects (UPGRADE)

Genetics of Drug Metabolism

United States
Jørgen Bjerggaard Jensen
Odense University Hospital; Karolinska University Hospital; Zealand University... and other collaborators

Recruiting

NORTH-REG Dwell-Time Study

Side Effect of Drug

Denmark, Sweden, Iceland
Lobe Sciences Ltd.
Pharmaceutical Research Unit, Jordan

Completed

Evaluation of Safety, Rate and Extent of Absorption of Psilocin Mucate (Psilocin-1)

Side Effect of Drug

Jordan
Companion Dx Reference Lab, LLC

Unknown

Pharmacogenomics Registry to Assess Clinical Utility (PREACT)

Drug Side Effects
Assiut University

Completed

Efficacy of Repetitive Trans-spinal Magnetic Stimulation on Axial Motor Symptoms in PD (rTSMS)

Adverse Effect of Drug Therapy Levodopa

Egypt
Mayo Clinic

Not yet recruiting

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: (PREPARE-Mayo)

Side Effect of Drug | Pharmacogenomic Drug Interaction | Drug Metabolism, Poor, CYP2D6-Related | Ineffective Drug Action | Drug Metabolism, Poor, CYP2C19-Related

United States
Sun Yat-sen University

Not yet recruiting

the SDMEAI Study: a Multi-center Epidemiological Study

Artificial Intelligence | Eye Involvement of Systemic Diseaes | Adverse Drug Effect on Eye
Seoul National University Hospital
Asan Medical Center; Myongji Hospital

Unknown

The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department

Side Effect of Drug | Sedation and Analgesia

Korea, Republic of
Fundação Bahiana de Infectologia
Hospital de Clinicas de Porto Alegre; Universidade Federal do Rio Grande do... and other collaborators

Recruiting

Dolutegravir and Clinical Outcomes Among ART-recipients in Brazil (CODE)

HIV Infections | Clinical Outcomes | Adverse Drug Event | Effect of Drugs

Brazil
St. Antonius Hospital
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

Postoperative Pain | Opioid Use | Side Effect of Drug

Netherlands
Wolfson Medical Center

Completed

The Use of STOPP/START Criteria for Medication Intervention Among Elderly Population Living in a Geriatric Hospital (STOPP)

Adverse Drug Effects

Israel
Clinical Hospital Centre Zagreb
Croatian Science Foundation; University of Zagreb School of Medicine

Recruiting

Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Cardiovascular Drugs

Croatia
Getz Pharma

Completed

Research on Human Insulin rDNA Safety and Efficacy in Patients With Type 2 Diabetes Mellitus (RISE)

Type 2 Diabetes Treated With Insulin | Adverse Drug Event | Effect of Drug

Pakistan
Tanta University

Completed

The Effect of Opioid Free Anesthesia in Bariatric Surgeries (Opioidfree)

Adverse Effect of Drugs and Medicaments in Therapeutic Use | Adverse Effects in the Therapeutic Use of Anaesthetics

Egypt
Renaissance RX
Syntactx

Unknown

Diagnosing Adverse Drug Reactions Registry (DART)

Genetics of Drug Metabolism

United States
Duke University
Boston Medical Center; Centers for Disease Control and Prevention; Children's...

Completed

FLUAD® vs. Fluzone® High-Dose Study

Quality of Life | Pain | Adverse Drug Event | Injection Site Reaction | Side Effect of Drug

United States
Saint-Joseph University

Completed

Evaluation of Efficacy and Safety of Subcutaneous Acetaminophen (APAPSubQ)

Pain | Fever | Drug Effect | Drug Reaction

Lebanon
Jinnah Postgraduate Medical Centre

Completed

Comparison of Efficacy of Tranexamic Acid Mesotherapy Versus 0.9% Normal Saline for Melasma

Effect of Drugs | Adverse Effects of Medical Drugs

Pakistan
Assaf-Harofeh Medical Center

Unknown

ACEIs and ARBs Treatment in Diabetic Patients -Drug Interactions and Adverse Drug Effects

Diabetes Mellitus Type 2

Israel
Oslo University Hospital

Active, not recruiting

Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals (MePhaCard)

Drug Effect | Adverse Drug Effect | Heart Arrhythmia

Norway
Alexandria University

Completed

Lubiprostone for Functional Constipation in the Under 18 Years Patients

Drug Side Effect | Treatment Efficacy | Clinical Efficacy

Egypt
Izmir Ataturk Training and Research Hospital

Not yet recruiting

The Effects Of Anticholinergic Burden On Daily Living Activities In Elderly Patients

Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Anticholinergic Adverse Reaction | Anticholinergic Syndrome | Antiarrhythmic Drug Adverse Reaction | Antiparkinsonism Drugs Causing Adverse Effects in Therapeutic Use | Antispasmodic Adverse Reaction
Universidade Federal do Rio de Janeiro

Recruiting

Immunomodulatory Effect of Dexmedetomidine as an Adjuvant Drug in Laparoscopic Cholecystectomies

Physiological Effects of Drugs

Brazil
Guangdong Provincial Hospital of Traditional Chinese...
Peking Union Medical College Hospital

Not yet recruiting

Efficacy and Safety of Expanded UCMSCs On Patients With Moderate to Severe Psoriasis (UCMSCs)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment in Patients With Moderate to Severe Psoriasis

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Peking University People's Hospital
Peking University Shougang Hospital; Jiangsu HengRui Medicine Co.

Recruiting

Apatinib Plus IE Chemotherapy (Ifosfamide and Etoposide) for Relapsed or Refractory Osteosarcoma (AIEO)

Effect of Drug | Toxicity, Drug

China
Diakonhjemmet Hospital
University of Oslo; Diakonhjemmet Hospital Pharmacy; Diakonhjemmet Foundation

Completed

Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial (EPIMERR)

Drug-Related Side Effects and Adverse Reactions | Drug Interaction Potentiation | Medication Compliance | Remission | Medicinal Substance; Adverse Effect

Norway
Andreas Benesic, MD
MetaHeps GmbH

Unknown

Cells of Monocytic Origin as Surrogate Markers for Individual Drug Effects and Hepatotoxicity

Adverse Reaction to Drug | Drug-induced Disorder of Liver

Hong Kong, Australia, Germany, Japan, Korea, Republic of
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis (ADMSP)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
NHS Greater Glasgow and Clyde
Public Health Scotland

Recruiting

ASSIST: A Surveillance Study of Illicit Substance Toxicity (ASSIST)

Drug Effect | Drug Use | Drug Abuse | Drug Toxicity | Illicit Drug Use | Overdose, Drug | Illicit Drug Overdose | Illicit Drug Intoxication

United Kingdom
Hasselt University
Jessa Hospital

Unknown

Measuring the Incidence of Hospital Readmissions Based on Adverse Drug Events

Incidence of Readmissions | ADE's Due to Anticoagulants

Belgium
Kasr El Aini Hospital

Recruiting

Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events

Tonsillectomy | Adenoidectomy | Drug-Related Side Effects and Adverse Reaction

Egypt
Zhejiang University

Completed

Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer

Quality of Life | Complications | Adverse Drug Event | Length of Stay | Hospital Costs

China
Chulalongkorn University
Mahidol University

Completed

Quality of Life of Patients With a History of Drug Allergy in Thailand

Quality of Life

Thailand
Bursa Yüksek İhtisas Education and Research Hospital

Completed

Evaluation of Deltoid Exercises on Injection Site Pain After (BNT162b2) COVID - 19 Vaccination

Injection Site Reaction | Vaccines, Adverse Effects

Turkey
Kwang Dong Pharmaceutical co., ltd.

Completed

Phase I Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics of KD101 in Healthy Male Subjects

Drug Toxicity

Korea, Republic of
Tanta University

Unknown

The Off Label Use of Glycopyrrolate in the Adults Intensive Care Unit.

Effect of Drugs

Saudi Arabia
Suez Canal University

Unknown

Dexmedetomidine Adjuvant to General Anesthesia of Abdominal Hysterectomy

Effect of Drugs
Beni-Suef University

Unknown

Comparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative Electroencephalograghy

Effect of Drugs
Peking University People's Hospital
Peking University Shougang Hospital

Completed

Apatinib + Ifosfamide and Etoposide for Relapsed or Refractory Osteosarcoma

Effect of Drug | Toxicity, Drug | Secondary Resistance

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Comparison of Chemoradiotherapy and Chemoradiotherapy Combined With Consolidation Chemotherapy for ESCC

Chemotherapy Effect | Esophageal Squamous Cell Carcinoma | Side Effect of Drug

China
University of Aarhus

Completed

Methadone in Cystectomy Patients (METAMORF)

Pathologic Processes | Pain | Pain, Postoperative | Postoperative Complications | Neurologic Manifestations | Bladder Cancer | Neurologic Symptoms | Signs and Symptoms | Side Effect of Drug

Denmark
Cedars-Sinai Medical Center
National Institute on Aging (NIA)

Not yet recruiting

Population Health Approach to Optimizing Medications in Older Adults (POP-MED)

Medication Adverse Effects

Clinical Trials on Metabolic Side Effects of Drugs and Substances

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