Clinical Trials on Metastatic Seminoma

Total 9398 results

Barts & The London NHS Trust
University College London Hospitals

Completed

Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma (Car-PET)

Metastatic Seminoma

United Kingdom
Daiichi Sankyo, Inc.

Terminated

ARQ 197 for Participants With Relapsed or Refractory Germ Cell Tumors

Non-CNS Germ Cell Tumors (Seminomas and Nonseminomas)

United States, France, United Kingdom
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Retroperitoneal Lymph Node Dissection in Treating Patients With Testicular Seminoma

Lymphadenopathy | Stage I Testicular Seminoma | Stage II Testicular Seminoma

United States
Abramson Cancer Center of the University of Pennsylvania
Massachusetts General Hospital

Completed

Proton Radiotherapy for Stage I, IIA, and IIB Seminoma

Stage I, IIA and IIB Seminoma

United States
University Health Network, Toronto

Recruiting

R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma

Stage II Testicular Seminoma | Lymphadenopathy Retroperitoneal

Canada
Tata Memorial Centre

Not yet recruiting

Radiotherapy vs Observation for Post Chemotherapy Residual Mass in Advanced Seminoma

Seminoma

India
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Therapeutic Strategy Guided by PET-TDM for Patients With Seminoma (SEMITEP)

Seminoma

France
Swiss Group for Clinical Cancer Research

Active, not recruiting

Therapy De-escalation in Seminoma Stage IIA/B

Seminoma

Germany, Switzerland
Heinrich-Heine University, Duesseldorf

Recruiting

PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND

Seminoma

Germany
Centre Hospitalier Universitaire Dijon

Unknown

Epigenetic Integrity of Spermatozoa in Patients With Germinal Testicular Tumours (GAMETH)

Seminomas

France
Centre Leon Berard

Recruiting

De-escalation Study for Stage IIa/IIb < 3 cm Seminoma (EDEN)

Seminoma | Stage II

France
Memorial Sloan Kettering Cancer Center
AstraZeneca

Active, not recruiting

Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors

Nonseminomatous Germ Cell Tumor | Seminoma | Germ Cell Tumor | Dysgerminoma | Pineal Germ Cell Tumor | Germinomatous Germ Cell Tumor

United States
Medical Research Council

Unknown

Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle

Testicular Germ Cell Tumor

United Kingdom
Jennifer King
Exelixis

Recruiting

A Phase II Trial of Cabozantinib With Patients With Refractory GCTs

Ovarian Germ Cell Tumor | Seminoma | Germ Cell Tumor | Non-seminomatous Germ Cell Tumor

United States
Medical Research Council
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular Cancer

Testicular Germ Cell Tumor

United Kingdom, Canada, Norway, Netherlands, South Africa, Brazil, Finland
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Cancer Research UK; European Organisation for... and other collaborators

Active, not recruiting

Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

Seminoma | Teratoma | Choriocarcinoma | Germinoma | Germ Cell Tumor | Yolk Sac Tumor | Mixed Germ Cell Tumor | Childhood Teratoma | Malignant Germ Cell Neoplasm | Extragonadal Seminoma | Non-seminomatous Germ Cell Tumor

United States, Germany, France, Spain, Netherlands, Australia, Belgium, Switzerland, United Kingdom, Italy, Denmark, Ireland
Haukeland University Hospital
Karolinska University Hospital; Oslo University Hospital; University Hospital... and other collaborators

Recruiting

MicroRNA as Markers in Testicular Cancer

Seminoma | Testicular Germ Cell Cancer | Non-Seminoma Testicular Cancer | Stage I Testicular Cancer | Stage II Testicular Cancer | Stage III Testicular Cancer | Stage IV Testicular Cancer | Relapse Testicular Cancer

Norway, Sweden
AHS Cancer Control Alberta

Completed

Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients

Seminoma | Testicular Cancer | Non-seminomatous

Canada
Simbec Research

Unknown

Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma

Testicular Germ Cell Tumor | Nausea and Vomiting
National Cancer Institute (NCI)

Terminated

Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer

Testicular Seminoma | Recurrent Ovarian Germ Cell Tumor | Stage II Ovarian Germ Cell Tumor | Stage III Ovarian Germ Cell Tumor | Ovarian Dysgerminoma | Recurrent Malignant Testicular Germ Cell Tumor | Stage II Malignant Testicular Germ Cell Tumor | Stage III Malignant Testicular Germ Cell Tumor

United States
Memorial Sloan Kettering Cancer Center

Completed

Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain

Metastatic Solid Tumors of Metastatic Disease

United States
St. Olavs Hospital
Karolinska Institutet; Oslo University Hospital; University Hospital of North... and other collaborators

Recruiting

Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer (SWENOTECA-ABC)

Testicular Neoplasms | Seminoma

Norway
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study of the Intra-patient Variability of the Quantitative Parameters of Tumor Perfusion Evaluated With Ultrasound Contrast (VARIA-DCE-US)

GIST Metastatic Cancer | Breast Metastatic Cancer | Kidney Metastatic Cancer | Colon Metastatic Cancer | Rectal Metastatic Cancer

France
University of California, San Diego

Active, not recruiting

Checkpoint Blockade Immunotherapy Combined With Stereotactic Body Radiation in Advanced Metastatic Disease

Metastatic Cancer

United States
Institut Investigacio Sanitaria Pere Virgili
Institut Català d'Oncologia; Hospital Universitario Ramon y Cajal; Hospital Arnau... and other collaborators

Recruiting

The Impact of Radiotherapy on Oligometastatic Cancer

Metastatic Colorectal Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Metastatic Prostate Cancer

Spain
David Palma

Recruiting

A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor. (SABR-SYNC)

Metastatic Tumor

Canada
Institut Claudius Regaud

Completed

Evaluation of an Organized Consultation "Return Home" of Patients With a Cancer (CREDO) (CREDO)

METASTATIC CANCER

France
UNICANCER

Completed

EXPRESS: EXcePtional RESponSe - Exceptional and Unexpected Response to Targeted Therapies (EXPRESS)

Metastatic Cancers

France
Queen Mary University of London

Recruiting

THERApy De-escalation for TESTicular Cancer (THERATEST)

Seminoma

United Kingdom
Swiss Group for Clinical Cancer Research
German Testicular Cancer Study Group

Active, not recruiting

Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma

Seminoma | Testicular Cancer

Germany, Switzerland
Genentech, Inc.

Active, not recruiting

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

Advanced/Metastatic Tumors

Spain, United States, Korea, Republic of, Australia, France, Japan, Canada
The Cooper Health System

Completed

Observation for Patients With Asymptomatic CNS Metastatic Disease

Cancer | Metastatic Cancer

United States
Memorial Sloan Kettering Cancer Center
AstraZeneca

Recruiting

A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer

Solid Tumor | Metastatic Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Solid Carcinoma | Metastatic Tumor

United States
Centre Hospitalier Universitaire de Besancon
National Cancer Institute, France

Completed

Allogenic Immunotherapy Based on Natural Killer (NK) Cell Adoptive Transfer in Metastatic Gastrointestinal Carcinoma Treated With Cetuximab (NK-EGFR01)

Gastrointestinal Metastatic Cancer

France
Duke University

Recruiting

Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data Registry

Metastatic Cancer | Oligometastasis

United States
AO Innovation Translation Center
AO Foundation, AO Spine

Recruiting

Metastatic Tumor Research and Outcomes Network (MTRON)

Metastatic Spine Tumor

United States, Canada, Hungary, Australia, Germany, Italy, Japan, Netherlands, Singapore, Switzerland
Bavarian Nordic

Completed

A Phase 1 Open Label Trial of Intravenous Administration of MVA-BN-Brachyury Vaccine in Patients With Advanced Cancer

Solid Metastatic Tumor

United States
Indiana University School of Medicine
Alaunos Therapeutics

Terminated

Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors

Stage IV Ovarian Germ Cell Tumor | Recurrent Ovarian Germ Cell Tumor | Extragonadal Seminoma | Recurrent Malignant Testicular Germ Cell Tumor | Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor | Stage IV Extragonadal Seminoma | Adult Central Nervous System Germ Cell Tumor | Adult Teratoma | Malignant... and other conditions

United States
Samsung Medical Center

Unknown

Chemotherapy Plus Reduced Radiotherapy in Intracranial Germinoma

Intracranial Germinoma

Korea, Republic of
Centre Leon Berard
Transgene

Completed

Immunization Strategy With Intra-tumoral Injections of Pexa-Vec With Ipilimumab in Metastatic / Advanced Solid Tumors. (ISI-JX)

Advanced Tumor | Metastatic Tumor

France
Stony Brook University
The University of Texas Health Science Center at San Antonio

Recruiting

Definitive Radiation for High-Risk Spine Metastases

Metastatic Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Spine Metastases | Metastatic Tumor | Metastatic Tumor of Bone | Metastatic Tumor to the Spine

United States
AstraZeneca

Completed

Phase I Orally Administered 14C-AZD2171 in Patients With Solid Metastatic Tumors

Advanced Solid Metastatic Tumor

United Kingdom
Children's Oncology Group

Not yet recruiting

Chemotherapy Followed by Response-Based Reduced Radiation Therapy for Patients With Central Nervous System Germinomas

Childhood Central Nervous System Germinoma | Intracranial Germ Cell Tumor
Institut de Cancérologie de la Loire
Saint-Louis Hospital, Paris, France; Gustave Roussy, Cancer Campus, Grand Paris

Withdrawn

Phase II Trial Assessing the Efficacy of Immuno-Radiation Abscopal Effect in Patients With Metastatic Cancers (IRAM)

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Head and Neck Cancer

France
Novartis Pharmaceuticals

Terminated

A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers

Metastatic and Advanced Solid Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings

Testicular Seminoma | Testicular Yolk Sac Tumor | Childhood Malignant Ovarian Germ Cell Tumor | Childhood Malignant Testicular Germ Cell Tumor | Ovarian Embryonal Carcinoma | Ovarian Yolk Sac Tumor | Testicular Embryonal Carcinoma | Ovarian Choriocarcinoma | Ovarian Mixed Germ Cell Tumor | Testicular Choriocarcinoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors

Stage IV Ovarian Germ Cell Tumor | Recurrent Ovarian Germ Cell Tumor | Stage III Testicular Cancer | Recurrent Malignant Testicular Germ Cell Tumor | Recurrent Extragonadal Seminoma | Recurrent Malignant Extragonadal Germ Cell Tumor | Recurrent Malignant Extragonadal Non-Seminomatous Germ Cell... and other conditions

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

Metastatic Cancers

United States
M.D. Anderson Cancer Center

Not yet recruiting

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

OligoProgressive Metastatic Disease

United States
I-Mab Biopharma Co. Ltd.

No longer available

Expanded Access Protocol for Subjects With Relapsed or Refractory Advanced Solid Tumors Receiving TJ210001

Solid Tumor Metastatic Cancer Advanced Cancer

Clinical Trials on Metastatic Seminoma

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