Clinical Trials on Mitral Valve Disease

Total 376539 results

Closed Joint-Stock Company NeoCor
Research Institute for Complex Problems of Cardiovascular Diseases, Russia; CT Medical Limited Liability Company

Recruiting

Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease

Diseases of Mitral and Aortic Valves | Valvular Heart Disease (Aortic and Mitral Valves) | Rheumatic Disorders of Mitral and Aortic Valves | Other Congenital Malformations of Aortic and Mitral Valves | Mitral Valve Insufficiency and Aortic Valve Insufficiency

Russian Federation
Abbott Medical Devices

Active, not recruiting

HALO: A Single Arm Prospective Investigation of the SJM™ Masters HP™ 15mm Rotatable Mechanical Heart Valve

Mitral Valve Disease | Damaged Mitral Valve | Malfunctioning Mitral Heart Valve | Mitral Valve Replacement

United States
Suez Canal University
National Research Centre, Egypt

Completed

Outcome of Preserved Mitral Valve Apparatus During Mitral Valve Replacement (EarlyOutcome)

Mitral Valve Replacement | Diseases of Mitral Valves | Abnormality of Mitral Valve Annulus (Disorder)

Egypt
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Left Atrial Fibrosis in Mitral Valve Repair Surgery (ALIVE Trial) (ALIVE)

Mitral Regurgitation | Surgery | Cardiac Valve Disease | Mitral Valve Disease | Mitral Valve Surgery | Mitral Valve Repair

Netherlands
Eric Y. Yang, MD PhD

Unknown

Primary Mitral Regurgitation Repair

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Ventricular Remodeling | Mitral Valve Disease | Degenerative Mitral Valve Disease | Chronic Mitral Disease | Myxomatous Mitral Valve Degeneration

United States
Caisson Interventional LLC

Active, not recruiting

Caisson Transcatheter Mitral Valve Replacement (TMVR) (INTERLUDE)

Mitral Regurgitation | Valve Disease, Heart | Valve Heart Disease | Mitral Valve Disease | Mitral Valve Failure | Mitral Disease

United States
University Hospital, Basel, Switzerland

Recruiting

Registry for Mitral Valve Surgery at Department of Cardiac Surgery University Hospital of Basel/ Switzerland

Mitral Valve Disease | Mitral Valve Surgery

Switzerland
Abbott Medical Devices

Recruiting

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT)

Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Valve Disease, Heart | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada
InnovHeart

Active, not recruiting

SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation

Heart Valve Diseases | Mitral Regurgitation | Valve Heart Disease | Mitral Valve Disease | Mitral Disease

Lithuania, Denmark, Hungary
Jenscare Scientific

Not yet recruiting

A Prospective, Multicenter Study to Evaluate the JensClip Transcatheter Valve Repair System

Mitral Valve Regurgitation | Degenerative Mitral Valve Disease
Foldax, Inc

Active, not recruiting

Clinical Investigation for the Foldax Tria Mitral Valve- India

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease | Mitral Stenosis

India
Pipeline Medical

Active, not recruiting

Chordal Repair for Transcatheter Mitral Valve Repair (TMVr)

Mitral Valve Regurgitation | Degenerative Mitral Valve Disease

Serbia, Georgia, Paraguay
Edwards Lifesciences

Not yet recruiting

ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral

Mitral Regurgitation | Mitral Valve Disease | Mitral Stenosis
Assistance Publique - Hôpitaux de Paris
European Association of Cardiovascular Imaging

Not yet recruiting

European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study (EACVI-MMVD)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Aortic Valve Stenosis With Insufficiency | Tricuspid Valve Insufficiency | Mitral Valve Disease | Tricuspid Valve Disease | Mitral Valve Insufficiency and... and other conditions

France
UMC Utrecht
Leiden University Medical Center; The Interuniversity Cardiology Institute... and other collaborators

Terminated

The Dutch Asymptomatic Mitral Regurgitation Trial (Dutch AMR)

Mitral Valve Insufficiency | Diseases of Mitral Valve | Heart; Disease, Mitral(Valve)

Netherlands
Synecor, LLC

Unknown

The Conveyor Study

Heart Failure | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Disease
Edwards Lifesciences

Active, not recruiting

PARTNER 3 Trial - Mitral Valve in Valve

Heart Failure | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Disease

United States, Australia, Brazil
Abbott Medical Devices

Completed

AVJ-514 Japan Trial

Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency | Functional Mitral Regurgitation | Mitral Stenosis With Insufficiency

Japan
Braile Biomedica Ind. Com. e Repr. Ltda.

Recruiting

Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Mitral Valve Regurgitation | Aortic Valve Incompetence | Mitral Valve Incompetence | Aortic Valve Regurgitation

Brazil
NeoChord

Recruiting

Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System (AcChord)

Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Disease

Germany, Greece, Switzerland
Lawson Health Research Institute

Unknown

Patient Specific Mitral Valve Modeling for Surgical Planning and Training

Mitral Regurgitation | Mitral Valve Prolapse | Mitral Valve Disease
Abbott Medical Devices

Completed

EVEREST II Pivotal Study High Risk Registry (HRR) (HRR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
Abbott Medical Devices

Completed

Pivotal Study of a Percutaneous Mitral Valve Repair System (EVERESTIIRCT)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
Abbott Medical Devices

Completed

Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Mitral Valve Regurgitation | Aortic Valve Incompetence | Mitral Valve Incompetence | Aortic Valve Regurgitation

United States
Foldax, Inc

Active, not recruiting

Early Feasibility Study for the Foldax TRIA Mitral Heart Valve Replacement (FOLDAX)

Mitral Valve Stenosis | Mitral Valve Disease | Mitral Valve Failure

United States
Abbott Medical Devices

Completed

Real World Expanded Multicenter Study of the MitraClip® System (REALISM) (REALISM)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
Abbott Medical Devices

Completed

Feasibility Study of a Percutaneous Mitral Valve Repair System. (EVEREST(I))

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
4C Medical Technologies, Inc.

Recruiting

AltaValve Early Feasibility Study Protocol

Mitral Regurgitation | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency | Mitral Incompetence

United States
Edwards Lifesciences

Terminated

REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System (REPAIR)

Heart Diseases | Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Cardiac Valve Annuloplasty | Mitral Valve Annuloplasty

Germany, Italy, France
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Evaluation of Mitral Valve Insufficiency Under General Anesthesia (MITIGATE)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Netherlands
Michele De Bonis

Completed

Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

Mitral Valve Disease

Italy
Boston Scientific Corporation

Active, not recruiting

A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation

Cardiovascular Diseases | Mitral Regurgitation Functional | Mitral Valve Disease

United States, Australia
Cardiovalve Ltd.
Meditrial Europe Ltd.; Meditrial SrL

Recruiting

AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System (AHEAD)

Mitral Regurgitation | Mitral Valve Disease

Germany, Italy, Greece
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE MRace: Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant (EXPLORE MRace)

Mitral Valve Disease

Brazil
P+F Products + Features GmbH
Meditrial USA Inc.

Not yet recruiting

Munich Transcatheter Mitral Valve Safety and Effectiveness (MUSE)

Mitral Regurgitation | Mitral Valve Disease

Brazil, Argentina, Chile
Polares Medical SA

Terminated

Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (EXPLORE MR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Switzerland, Germany
Edwards Lifesciences

Recruiting

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

Mitral Regurgitation | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada, Switzerland, Germany
Deutsches Herzzentrum Muenchen

Recruiting

The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry (OBSERV-MITRA)

Mitral Valve Stenosis | Mitral Valve Regurgitation | Tricuspid Valve Regurgitation

Germany
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation

Mitral Regurgitation | Degenerative Mitral Valve Disease

China
Polares Medical SA

Terminated

Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation (EXPLORE DMR)

Degenerative Mitral Valve Disease

United States
Michele De Bonis

Completed

Commissural Closure to Treat Severe Mitral Regurgitation: Standing the Test of Time.

Degenerative Mitral Valve Disease

Italy
Hangzhou Valgen Medtech Co., Ltd

Enrolling by invitation

Safety and Effectiveness Study of Dragonfly System for Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease

China
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease
Abbott Medical Devices

Active, not recruiting

Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification

Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Insufficiency | Valve Heart Disease | Mitral Annulus Calcification | Mitral Valve Disease | Mitral Annular Calcification | Heart Valve Calcification

United States
Enlight Medical Technologies (Shanghai) Co., Ltd

Active, not recruiting

Clinical Study of NovoClasp for Treating Moderate to Severe and Severe Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease

China
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - First In Human Israel (TWIST-FIHIL)

Mitral Valve Regurgitation (Degenerative or Functional)

Israel
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Pilot in Georgia (TWIST-PILOT-GE)

Mitral Valve Regurgitation (Degenerative or Functional)

Georgia
Innovalve Bio Medical Ltd.

Not yet recruiting

TVMR With the Innovalve System Trial - TWIST-BE TWIST-PILOT-BE

Mitral Valve Regurgitation (Degenerative or Functional)
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Pilot Study in Italy (TWIST-PILOT-IT)

Mitral Valve Regurgitation (Degenerative or Functional)

Italy
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Early Feasibility Study (TWIST-EFS)

Mitral Valve Regurgitation (Degenerative or Functional)

United States

Clinical Trials on Mitral Valve Disease

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