Clinical Trials on Mitral Valve Insufficiency

Total 30169 results

Closed Joint-Stock Company NeoCor
Research Institute for Complex Problems of Cardiovascular Diseases, Russia; CT Medical Limited Liability Company

Recruiting

Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease

Diseases of Mitral and Aortic Valves | Valvular Heart Disease (Aortic and Mitral Valves) | Rheumatic Disorders of Mitral and Aortic Valves | Other Congenital Malformations of Aortic and Mitral Valves | Mitral Valve Insufficiency and Aortic Valve Insufficiency

Russian Federation
Assistance Publique - Hôpitaux de Paris
European Association of Cardiovascular Imaging

Not yet recruiting

European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study (EACVI-MMVD)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Aortic Valve Stenosis With Insufficiency | Tricuspid Valve Insufficiency | Mitral Valve Disease | Tricuspid Valve Disease | Mitral Valve Insufficiency and... and other conditions

France
Abbott Medical Devices

Completed

AVJ-514 Japan Trial

Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency | Functional Mitral Regurgitation | Mitral Stenosis With Insufficiency

Japan
Abbott Medical Devices

Recruiting

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT)

Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Valve Disease, Heart | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada
Abbott Medical Devices

Completed

EVEREST II Pivotal Study High Risk Registry (HRR) (HRR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
Abbott Medical Devices

Completed

Pivotal Study of a Percutaneous Mitral Valve Repair System (EVERESTIIRCT)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
Abbott Medical Devices

Completed

Real World Expanded Multicenter Study of the MitraClip® System (REALISM) (REALISM)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
Abbott Medical Devices

Completed

Feasibility Study of a Percutaneous Mitral Valve Repair System. (EVEREST(I))

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency

United States
4C Medical Technologies, Inc.

Recruiting

AltaValve Early Feasibility Study Protocol

Mitral Regurgitation | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency | Mitral Incompetence

United States
Deutsches Herzzentrum Muenchen

Recruiting

The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry (OBSERV-MITRA)

Mitral Valve Stenosis | Mitral Valve Regurgitation | Tricuspid Valve Regurgitation

Germany
Edwards Lifesciences

Recruiting

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

Mitral Regurgitation | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada, Switzerland, Germany
Edwards Lifesciences

Active, not recruiting

Edwards Cardioband European Post-Market Study, MiBAND (MiBAND)

Mitral Regurgitation | Mitral Insufficiency | Mitral Repair | Mitral Valve | Annuloplasty | Edwards Cardioband

Switzerland, Germany, Italy
Federal University of Bahia

Completed

Beating Versus Arrested Heart for Mitral Valve Replacement (BAHMVR)

Mitral Insufficiency | Mitral Stenosis

Brazil
CSD Labs GmbH

Completed

Automated Phonocardiography Analysis in Adults

Aortic Stenosis | Mitral Insufficiency | Tricuspid Regurgitation | Aortic Insufficiency | Mitral Insufficiency and Aortic Stenosis | Insufficiency, Pulmonary | Insufficiency, Tricuspid

Austria
Universitätsklinikum Hamburg-Eppendorf
University Hospital, Bordeaux; Montreal Heart Institute

Recruiting

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry (CHOICE-MI)

Mitral Regurgitation

Switzerland, United States, Denmark, United Kingdom, France, Canada, Germany, Australia, Italy, Norway
Medtentia International Ltd Oy

Completed

5-Year Follow-Up Safety and Performance Evaluation of the Medtentia Annuloplasty Ring in Adults

Mitral Regurgitation | Mitral Insufficiency

Finland
Medical College of Wisconsin
Children's Hospital and Health System Foundation, Wisconsin

Completed

Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI

Mitral Valve Regurgitation | Tricuspid Valve Regurgitation, Non-rheumatic

United States
Edwards Lifesciences

Recruiting

MiCLASP Post Market Clinical Follow-Up (PMCF) Study (MiCLASP)

Mitral Regurgitation | Mitral Insufficiency

Switzerland, Germany, Austria, Greece, Italy, Netherlands, Poland, Spain, United Kingdom
Medtentia International Ltd Oy

Terminated

Study on Safety and Performance of Medtentia Mitral Valve Repair System in Surgical Repair of Mitral Regurgitation

Mitral Regurgitation | Mitral Insufficiency

Finland
Atlantic Health System

Recruiting

Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation

Mitral Regurgitation | Aortic Regurgitation

United States
Ospedale San Raffaele

Unknown

Expiratory Flow Limitation and Mechanical Ventilation During Cardiopulmonary Bypass in Cardiac Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Michele De Bonis

Completed

LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Oxford University Hospitals NHS Trust
Edwards Lifesciences

Recruiting

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety (EARLY-Edge)

Heart Failure | Mitral Regurgitation | Tricuspid Regurgitation | Mitral Repair

United Kingdom
Konkuk University Medical Center

Completed

Acute Normovolemic Hemodilution on Serum-creatinine Concentration in Cardiac Surgery

Mitral Regurgitation | Tricuspid Regurgitation | Mitral Stenosis

Korea, Republic of
Konkuk University Medical Center

Completed

Acute Normovolemic Hemodilution on ROTEM in Cardiac Surgery

Mitral Regurgitation | Tricuspid Regurgitation | Mitral Stenosis

Korea, Republic of
Ramsay Générale de Santé
European Clinical Trial Experts Network

Recruiting

Hemodynamic Estimation of the Result of the MitraClip Technique: Interest of the Ratio of Mean Arterial Pressure (MAP) to Pressure of the Mean Left Atrium (POG) (MitraPOG) (MitraPOG)

Mitral Insufficiency | Mitraclip

France
Pipeline Medical

Active, not recruiting

Chordal Repair for Transcatheter Mitral Valve Repair (TMVr)

Mitral Valve Regurgitation | Degenerative Mitral Valve Disease

Serbia, Georgia, Paraguay
Ullevaal University Hospital

Completed

Comparison of Blood Cardioplegia and Custodiol

Myocardial Protection | Mitral Insufficiencies

Norway
Medical University of Warsaw
Institute of Cardiology, Warsaw, Poland; Medical University of Lodz; Medical... and other collaborators

Recruiting

Polish Transcatheter Transfemoral Mitral Valve-in-Valve Implantation (Mitral ViV) Registry

Heart Failure | Mitral Insufficiency | Mitral Stenosis | Mitral Stenosis With Insufficiency | Bioprosthesis Failure

Poland
Jenscare Scientific

Not yet recruiting

A Prospective, Multicenter Study to Evaluate the JensClip Transcatheter Valve Repair System

Mitral Valve Regurgitation | Degenerative Mitral Valve Disease
Edwards Lifesciences

Terminated

A Clinical Study of the CardiAQ™ TMVI System (Transapical DS)

Cardiovascular Disease | Heart Disease | Heart Valve Disease | Mitral Insufficiency

Netherlands, United Kingdom, Denmark, France
Braile Biomedica Ind. Com. e Repr. Ltda.

Recruiting

Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Mitral Valve Regurgitation | Aortic Valve Incompetence | Mitral Valve Incompetence | Aortic Valve Regurgitation

Brazil
Centre Chirurgical Marie Lannelongue

Completed

Transcatheter Para-Valvular Leak Closures (FFPP1)

Cardiac Catheterization | Cardiac Valve Disease | Paravalvular Aortic Regurgitation | Paravalvular Mitral Regurgitation
Abbott Medical Devices

Completed

Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Mitral Valve Regurgitation | Aortic Valve Incompetence | Mitral Valve Incompetence | Aortic Valve Regurgitation

United States
Edwards Lifesciences

Withdrawn

Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS)

Cardiovascular Disease | Heart Disease | Heart Valve Disease | Mitral Insufficiency
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Strategies in Improving Left Ventricular Function After Mitral Repair

Congenital Mitral Insufficiency

China
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE MRace: Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant (EXPLORE MRace)

Mitral Valve Disease

Brazil
P+F Products + Features GmbH
Meditrial USA Inc.

Not yet recruiting

Munich Transcatheter Mitral Valve Safety and Effectiveness (MUSE)

Mitral Regurgitation | Mitral Valve Disease

Brazil, Argentina, Chile
Polares Medical SA

Terminated

Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (EXPLORE MR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Switzerland, Germany
Abbott Medical Devices
Abbott

Active, not recruiting

MitraClip EXPAND G4 Study

Mitral Regurgitation | Mitral Valve Regurgitation

United States, Canada, Spain, Israel, Germany, Italy, Japan, France, Netherlands, Saudi Arabia
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea

Completed

Transcatheter Mitral Valvuloplasty Pilot Study (MitraClip)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Regurgitation

Korea, Republic of
Abbott Medical Devices
Abbott

Completed

The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices

Mitral Regurgitation | Mitral Valve Regurgitation

Netherlands, United Kingdom, United States, Spain, Israel, Germany, Italy, Switzerland
Nanjing Medical University
The First Affiliated Hospital of Anhui Medical University; Nanjing First Hospital... and other collaborators

Not yet recruiting

Concomitant Tricuspid Repair in Patients With Left Heart Surgery

Mitral Regurgitation | Cardiopulmonary Bypass | Tricuspid Regurgitation

China
Synecor, LLC

Unknown

The Conveyor Study

Heart Failure | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Disease
UMC Utrecht
Leiden University Medical Center; The Interuniversity Cardiology Institute... and other collaborators

Terminated

The Dutch Asymptomatic Mitral Regurgitation Trial (Dutch AMR)

Mitral Valve Insufficiency | Diseases of Mitral Valve | Heart; Disease, Mitral(Valve)

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Left Atrial Fibrosis in Mitral Valve Repair Surgery (ALIVE Trial) (ALIVE)

Mitral Regurgitation | Surgery | Cardiac Valve Disease | Mitral Valve Disease | Mitral Valve Surgery | Mitral Valve Repair

Netherlands
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Investigation of Heart Function in Patients With Heart Valve Defects

Mitral Valve Insufficiency | Aortic Valve Insufficiency

United States
Edwards Lifesciences

Active, not recruiting

PARTNER 3 Trial - Mitral Valve in Valve

Heart Failure | Mitral Valve Insufficiency | Mitral Valve Regurgitation | Mitral Valve Disease

United States, Australia, Brazil
Michele De Bonis

Completed

Fate of Moderate Secondary Mitral Regurgitation in Patients Undergoing Aortic Valve Surgery for Severe Aortic Regurgitation

Aortic Regurgitation | Functional Mitral Regurgitation

Italy
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Evaluation of Mitral Valve Insufficiency Under General Anesthesia (MITIGATE)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Netherlands

Clinical Trials on Mitral Valve Insufficiency

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