Clinical Trials on Mucociliary Clearance Defect

Total 5458 results

Hospital de Clinicas de Porto Alegre

Completed

Comparison of Three Technical Airway Clearance in Mechanical Ventilated Patients (ClearanceMV)

Physical Disability | Mucociliary Clearance Defect
AstraZeneca

Recruiting

Study to Assess Effect of HFO MDI Propellant on Mucociliary Clearance Compared to HFA MDI Propellant in Healthy Participants

Mucociliary Clearance

United States
Chiesi Farmaceutici S.p.A.

Completed

Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance

Mucociliary Clearance

United Kingdom
University of North Carolina, Chapel Hill
Reckitt Benckiser Inc.

Completed

Evaluating the Effect of Mucinex® 1200 mg on Mucociliary and Cough Clearance From the Human Lung

Mucociliary Clearance

United States
Johns Hopkins University
Sunovion

Completed

Mucociliary Clearance in Healthy Subjects: Comparison of Levalbuterol and Racemic Albuterol

Mucociliary Clearance

United States
University of Missouri-Columbia

Recruiting

Symptom Based Performance of Airway Clearance After Starting Highly Effective Modulators for Cystic Fibrosis (SPACE-CF) (SPACE-CF)

Cystic Fibrosis | Mucociliary Clearance Defect

United States
University of North Carolina, Chapel Hill
Cystic Fibrosis Foundation

Completed

Researching the Effects of Airway Clearance Therapies in Cystic Fibrosis (REACT-CF)

Cystic Fibrosis | Mucociliary Clearance Defect

United States
Gilead Sciences

Withdrawn

A Phase 1 Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS 9411 in Subjects With Cystic Fibrosis (CF)

Cystic Fibrosis | Mucociliary Clearance

Australia
Gilead Sciences

Completed

A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Trial of GS-9411 in Healthy Volunteers

Cystic Fibrosis | Mucociliary Clearance | Airway Hydration

Australia
Gilead Sciences

Completed

A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS-9411 in Healthy Male Volunteers

Cystic Fibrosis | Mucociliary Clearance | Airway Hydration

Australia
Asklepion Pharmaceuticals, LLC

Completed

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol

Atrial Septal Defect | Atrioventricular Septal Defect | Ventricular Septal Defect

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Augmented Renal Clearance in the Adult Non-critically Ill Surgery Patient: a Prospective Point Prevalance Study (ARCPPS)

Prevalence of Augmented Renal Clearance | Risk Factors for Augmented Renal Clearance

Belgium
Shanghai 10th People's Hospital

Not yet recruiting

Effects of Intrapulmonary Percussive Ventilator on Respiratory Function

Airway Clearance Impairment

China
Eastern Virginia Medical School

Unknown

Role of Acetylcysteine in Creatinine Clearance

Creatinine Clearance

United States
Nobles Medical Technologies II Inc

Enrolling by invitation

Stitch Closure of PFO and Septal Repair (STITCH)

Foramen Ovale, Patent | Septal Defect, Atrial | Septal Defect, Heart

United States, Italy
HeartStitch.Com

Unknown

Stitch Closure of PFO and Septal Repair (STITCH)

Foramen Ovale, Patent | Septal Defect, Atrial | Septal Defect, Heart

United States
Asklepion Pharmaceuticals, LLC

Recruiting

A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Atrioventricular Septal Defect | Ventricular Septal Defect | Primum Atrial Septal Defect

United States
Nationwide Children's Hospital

Completed

Measures to Lower the Stress Response in Pediatric Cardiac Surgery

Tetralogy of Fallot (TOF) | Ventricular Septal Defects (VSD) | Atrioventricular Septal Defects (AVSD)

United States
Occlutech International AB

Completed

Occlutech Septal Occluder (Figulla Flex II) Study

Secundum Atrial Septal Defects
Abbott Medical Devices

Recruiting

Trevisio Post-Approval Study (TrevisioPAS)

PFO - Patent Foramen Ovale | VSD - Muscular Ventricular Septal Defect | PIVSD - Post Infarct Muscular Ventricular Septal Defect | ASD - Atrial Septal Defect

Spain, Germany, Poland, France, Italy, Netherlands, Switzerland
Ayman khairy Mohamed

Completed

Assessment of LV/RV S and SR Before and After Percutaneous Closure of ASDs

Atrial Septal Defect, Secundum Type

Egypt
Abbott Medical Devices

Terminated

ADVANCE ASO AMPLATZER™ Atrial Septal Occluder Post Market Surveillance Study (ASO 522)

Atrial Septal Defect Secundum

United States
Rush University Medical Center

Recruiting

Outcome Comparisons of Vibratory Airway Clearance Devices

Airway Clearance Impairment

United States
Duke University
Teleflex

Terminated

EFFEXTS OF THE CLEANSWEEP SUCTION CATHETER

Endotracheal Tube Clearance

United States
The Cleveland Clinic
Eisai Inc.

Withdrawn

Fospropofol for Sedation During Elective Awake Intubation

Impaired Airway Clearance

United States
National Taiwan University Hospital

Completed

Establishment of a Creatinine Clearance Estimation Equation and Daily Creatinine Excretion Reference Table for Taiwanese

Estimated Creatinine Clearance
Jordi Villalba Modol

Unknown

An Observational, Prospective Study of Patients With Chondral and/or Osteochondral Defects of the Knee Treated With NAMIC (KNAMIC)

Chondral Defect | Osteochondral Defect

Spain
Occlutech International AB

Recruiting

Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® mVSD Cases (mVSD Registry)

Muscular Ventricular Septal Defect

Turkey
Hill-Rom

Completed

Evaluation of High-Frequency Chest Wall Oscillation

Airway Secretion Clearance

United States
Odense University Hospital
Novartis; Danish Research Agency

Completed

Induction of Drug Metabolism: In Vivo Comparison of Carbamazepine and Oxcarbazepine.

Metabolic Clearance Rate

Denmark
Assiut University

Withdrawn

Outcomes of Transcatheter ASD Closure Guided by 3D-TEE

ASD2(Secundum Atrial Septal Defect)
Chinese Academy of Medical Sciences, Fuwai Hospital

Unknown

Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal Defect

Perimembranous Ventricular Septal Defect

China
Occlutech International AB

Active, not recruiting

A Multicenter, International, Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® PmVSD Occluder in Patients With Perimembranous Ventricular Septal Defects

Perimembranous Ventricular Septal Defect

Thailand, Germany, Ireland, Vietnam
W.L.Gore & Associates

Completed

Safety and Efficacy of the GORE® Septal Occluder to Treat Ostium Secundum Atrial Septal Defects

Septal Defect, Atrial

United States
Centre Hospitalier Universitaire Dijon

Completed

Creatinine Clearance as a Predictor of Successful Withdrawl of Continuous Renal Replacement Therapy in Intensive Care (STOP EERc)

Creatinine Clearance | Dialysis Withdrawal

France
Tungs' Taichung Metroharbour Hospital

Completed

Effect of Replacement Volume of Haemodiafiltration and AST-120 on Toxins, Oxidative Stress and MicroInflammation

Loss of Solute Clearance

Taiwan
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
Alyn Pediatric & Adolescent Rehabilitation Hospital
Beijing Anzhen Hospital

Completed

In-line Mechanical Insufflation-Exsufflation in the Management of Ventilated Patients

Ventilation Therapy; Complications | Airway Clearance Impairment
W.L.Gore & Associates

Completed

Long-term Safety Study of the GORE® HELEX® Septal Occluder

Septal Defect, Atrial

United States
Henry Ford Health System

Withdrawn

Iatrogenic Atrial Septal Defect Study (iASD) (iASD)

Septal Defect, Atrial

United States
University Hospital, Toulouse
Philips Healthcare

Completed

Percutaneous Closure of Atrial Septal Defects in Children: Integration of 3D Echocardiography and Fluoroscopy Imaging. (CIA3DNAVIGATOR)

Atrial Septal Defects

France
Institute of Cardiology, Warsaw, Poland

Unknown

Occluder Size Determination in Transcatheter ASD II Closure Based on 3D TEE Assessment

Ostium Secundum Atrial Septal Defect

Poland
Ain Shams University

Completed

Transcatheter Versus Surgical Closure of Ventricular Septal Defect: A Comparative Study

Heart Defects, Congenital

Egypt
Xijing Hospital

Completed

Transcatheter Closure Versus Surgery of Perimembranous Ventricular Septal Defects

Ventricular Septal Defects
Abbott Medical Devices

Active, not recruiting

Closure of Muscular Ventricular Septal Defects (VSDs) With the AMPLATZER Muscular VSD (MuVSD) Occluder - Post Approval Study (VPA)

Ventricular Septal Defects

United States, Canada
Shanghai Zhongshan Hospital

Recruiting

The Puncturable Atrial Septal Defect Occluder Trial (the PASSER Trial)

Atrial Septal Defect

China
University Health Network, Toronto
St. Paul's Hospital, Canada; Montreal Heart Institute; Centre de Recherche de...

Recruiting

Comparison of Devices for Atrial Septal Defects Closure: A Pilot Study (Trio-ASD)

Atrial Septal Defect

Canada
Nanjing Medical University

Completed

Hybrid Closure of Congenital Heart Disease

Pediatric Ventricular Septal Defects
Duke University
The Society of Pediatric Anesthesia

Recruiting

Regional Anesthesia Following Pediatric Cardiac Surgery

Atrial Septal Defect | Pain, Procedural | Ventricular Septal Defect

United States
University Hospital, Toulouse

Completed

Pharmacokinetics of Piperacillin/Tazobactam in Patients Treated by Continuous Renal Replacement Therapy (PTCRRT)

Diffusive and Convective Clearance | Body Clearance | Piperacillin Tazocilline Concentrations (Cmin)

France

Clinical Trials on Mucociliary Clearance Defect

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