Clinical Trials on Neoplasm, Residual

Total 106469 results

University of Leicester

Active, not recruiting

Minimal Residual Disease: A Trial Using Liquid Biopsies in Solid Malignancies. (MARTINI)

Cancer

United Kingdom
Zhiyong Yu

Not yet recruiting

Capecitabine Versus Vinorelbine in High Risk Breast Cancer With Pathologic Residual Tumors After Preoperative Chemotherapy

Pathologic Residual Cancer Cells

China
Karolinska University Hospital
Medical University of Graz; Aarhus University Hospital; Centre Hospitalier Universitaire... and other collaborators

Enrolling by invitation

GUIDING MULTI-MODAL THERAPIES AGAINST MINIMAL RESIDUAL DISEASE BY LIQUID BIOPSIES (GUIDEMRD)

Pancreatic Adenocarcinoma

Sweden
University Hospital, Clermont-Ferrand

Unknown

Contamination of Testicle Tissue by RT-PCR in Participants With Solid Tumors (TESTIMAR)

Minimal Residual Disease | Fertility Preservation

France
Guangdong Provincial People's Hospital
Shenzhen Chipscreen Biosciences Co.Ltd

Recruiting

A Study of Chidamide With AZA in MRD Positive AML After Transplant

Minimal Residual Disease | AML, Adult

China
University of Ulm
Brainlab AG

Recruiting

Evaluation of 3D Ultrasound in Brain Tumor Surgery (Neuro3DUS)

Residual Tumor

Germany
Institute of Hematology & Blood Diseases Hospital

Recruiting

Natural Killer(NK) Cell Therapy for AML Minimal Residual Disease

Minimal Residual Disease

China
University Hospital, Clermont-Ferrand

Unknown

Contamination of Ovarian Tissue by RT-PCR in Participants With Solid Tumors (OVAMAR)

Minimal Residual Disease | Fertility Preservation

France
Zhejiang University

Completed

MRD Monitoring by Digital Droplet PCR in the Early Period After Allo-HSCT to Predict Patients at High Risk of Relapse

Measurable Residual Disease

China
Xianmin Song, MD

Recruiting

Next Generation Sequencing（NGS）Monitors Minimal Residual Disease（MRD）in Allo-PBSCT Patients

NGS Monitor MRD

China
M.D. Anderson Cancer Center

Suspended

A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD)

Colon Cancer | Resected Stage

United States
Centre Hospitalier Universitaire de Besancon
University Hospital, Rouen; CHU de Reims; Central Hospital, Nancy, France; University... and other collaborators

Completed

Investigating Minimal Residual Disease in Autopreserved Ovarian Tissue in Cases of Neoplastic Pathology (OVAGRAFT)

Neoplastic Pathology | Autopreserved Ovarian Tissue

France
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

A Study of Olverembatinib Combined With Inotuzumab Ozogamicin in the Treatment ph+ ALL With MRD Persistent Positive

Minimal Residual Disease | Bone Marrow Transplant | Ph+ ALL

China
Centre Hospitalier Universitaire de Besancon
University Hospital, Rouen; Central Hospital, Nancy, France; University Hospital... and other collaborators

Completed

Validation of a Method to Search Residual Disease in Auto-cryopreserved Ovarian Tissues (VMRDO)

Minimal Residual Disease | Neoplastic Pathology | Cryopreserved Ovarian Tissue

France
WeiWei Xiao
Haplox Biotechnology Co., Ltd.

Recruiting

Predicting the Efficacy and Prognosis of Rectal Cancer Patients Based on ctDNA-MRD Technology

Minimal Residual Disease | Circulating Tumor DNA | Rectal Adenocarcinoma | Neoadjuvant Chemoradiotherapy

China
Peking University People's Hospital

Unknown

Interferon α for the Therapy of Minimal Residual Disease

Leukemia

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Stem Cell Transplant to Treat Patients With Favorable or Intermediate Risk Minimal Residual Disease Negative Acute Myeloid Leukemia

Acute Myeloid Leukemia | Minimal Residual Disease Negativity

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood and Bone Marrow Samples From Select Patients With CML to Measure Minimal Residual Disease

Leukemia

United States
Peking University People's Hospital

Recruiting

Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction

Acute Leukemia | MDS | CML | MDS/MPN

China
Gruppo Italiano Malattie EMatologiche dell'Adulto

Not yet recruiting

Kinetics and Impact on Survival of MRD in AML Patients Receiving Azacitidine and Venetoclax

Minimal Residual Disease | AML, Adult
Lumicell, Inc.
National Cancer Institute (NCI)

Completed

Intraoperative Detection of Residual Cancer in Breast Cancer

Breast Cancer

United States
Nanfang Hospital of Southern Medical University

Unknown

HMA+DLI vs DLI Preemptive Therapy Based on MRD for AL Undergoing Allo-HSCT

Minimal Residual Disease,Acute Leukemia, Hypomethylating Agents, Donor Lymphocyte Infusion, Allogeneic Hematopoietic Cell Transplantation

China
University Hospital Heidelberg
German Cancer Research Center; University Hospital Dresden

Terminated

Evaluation of Measurable Residual Disease in Patients With Acute Myeloid Leukemia as Surrogate Endpoint for Survival (PERDAM)

Leukemia, Myeloid, Acute

Germany
Hoffmann-La Roche
NSABP Foundation Inc; German Breast Group

Active, not recruiting

A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)

Breast Cancer

United States, Italy, United Kingdom, Canada, Czechia, Argentina, Austria, Belgium, Brazil, China, France, Germany, Guatemala, Ireland, Panama, Spain, Sweden, Taiwan, Turkey, Colombia, Hong Kong, Peru, Switzerland, South Africa, Israel, G... and more
University of Maryland, Baltimore

Active, not recruiting

Blinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPAL

Mixed Phenotype Acute Leukemia (MPAL) | Measurable Residual Disease (MRD)

United States
Abramson Cancer Center at Penn Medicine

Recruiting

ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer (ABBY)

Breast Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 Trial

Leukemia
Amgen

Terminated

A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies

Myelodysplastic Syndrome | Relapsed/Refractory AML | Minimal Residual Disease Positive AML

United States, Canada, Germany, Netherlands
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Completed

MRD-directed Donor Lymphocyte Infusion for Reduce of Relapse After Allo-HSCT

Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Relapse | Donor Lymphocyte Infusion

China
Shandong Cancer Hospital and Institute

Not yet recruiting

Capecitabine in HER-2 Positive Breast Cancer With Pathologic Residual Tumors After Preoperative Chemotherapy

HER2-positive Breast Cancer
University Hospital, Lille
Saint-Louis Hospital, Paris, France; Canceropôle Nord Ouest

Recruiting

Minimal Residual Disease Evaluation on Cryopreserved Ovarian Fragments in Younger Patients Treated for Acute Myeloid Leukemia (FERTILAM)

Acute Myeloid Leukemia

France
Enterome

Completed

EO2040 in Combination With Nivolumab, for Treatment of Patients With Minimal Residual Disease of Colorectal Cancer (CLAUDE)

Colorectal Cancer

United States
UNC Lineberger Comprehensive Cancer Center

Completed

Pilot Evaluation of a Microfluidic Assay to Detect Minimal Residual Disease and Predict Relapse in AML Patients

Acute Myeloid Leukemia

United States
Shanghai iCELL Biotechnology Co., Ltd, Shanghai...
Hebei Yanda Ludaopei Hospital

Unknown

Natural Killer Cells Infusion for Treating Acute Myeloid Leukemia Patients With Minimal Residual Disease

Acute Myeloid Leukemia

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Completed

MRD-directed Therapy for Low-risk and Intermediate-risk AML.

Acute Myeloid Leukemia | Minimal Residual Disease

China
University Medical Center Ho Chi Minh City (UMC)

Recruiting

Monitoring Minimal Residual Disease in Gastric Cancer by Liquid Biopsy Study Description

Gastric Cancer | ctDNA

Vietnam
Gruppo Oncologico del Nord-Ovest

Not yet recruiting

Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease (TRINITY)

Gastric Cancer | HER2-positive Gastric Cancer

Italy
The Institute of Molecular and Translational Medicine...
Brno University Hospital; Tomas Bata Hospital, Czech Republic

Completed

Effects of Different Types of Perioperative Analgesia on Minimal Residual Disease Development After Colon Cancer Surgery

Colon Cancer | Minimal Residual Disease

Czechia
University of Ulm

Terminated

Maintenance Therapy With Histamine Dihydrochloride and Interleukin-2 in Adult Acute Myeloid Leukemia (AML) Patients With Measurable Minimal Residual Disease (MRD)- a Non-interventional Study (NIS)

Acute Myeloid Leukemia

Germany
Hebei Medical University Fourth Hospital

Recruiting

Minimally Residual of Esophageal Cancer 001 (ECMRD-001)

Esophageal Carcinoma | Minimal Residual Disease

China
Peking Union Medical College Hospital
Peking University Cancer Hospital & Institute; Beijing Obstetrics and Gynecology... and other collaborators

Recruiting

Detection of Minimal Residual Disease Based on HPV ctDNA in Cervical Cancer

Uterine Cervical Neoplasms

China
M.D. Anderson Cancer Center
Taiho

Recruiting

TAS-102 in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

Colorectal Cancer

United States
Universitätsmedizin Mannheim

Suspended

Early Stereotactic Gamma Knife Radiosurgery to Residual Tumor After Surgery of Newly Diagnosed Glioblastoma (Gamma-GBM)

Glioblastoma

Germany
M.D. Anderson Cancer Center

Recruiting

DAILY: Vitamin D, Aspirin, ExercIse, Low Saturated Fat Foods StudY in Colorectal Cancer Patients With Minimal Residual Disease

Colorectal Cancer | Colon Cancer

United States
National Taiwan University Hospital

Unknown

HBV-host cfDNA as Minimal Residual Tumor Marker for HBV-related HCC

Carcinoma, Hepatocellular

Taiwan
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Exact Sciences Corporation
NSABP Foundation Inc

Recruiting

CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United States
Tampere University Hospital

Active, not recruiting

Measuring Molecular Residual Disease in Colorectal Cancer After Primary Surgery and Resection of Metastases

Colorectal Cancer | Residual Disease

Finland
Washington University School of Medicine
Taiho Oncology, Inc.

Recruiting

Pre-emptive Therapy With DEC-C to Improve Outcomes in MDS Patients With Measurable Residual Disease Post Allogeneic Hematopoietic Cell Transplant

Myelodysplastic Syndromes

United States
Institute of Hematology & Blood Diseases Hospital
Hangzhou Qihan Biotech Co.,Ltd.

Not yet recruiting

Natural Killer(NK) Cell Therapy in Acute Myeloid Leukemia

Minimal Residual Disease | AML, Adult

China

Clinical Trials on Neoplasm, Residual

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