Clinical Trials on Neoplasms, Rectal

Total 175774 results

Sixth Affiliated Hospital, Sun Yat-sen University

Unknown

Bevacizumab-containing Regimen for Metastatic Colorectal Cancer Failed to Cytotoxic Treatment (BATTLE)

Colorectal Cancer | Neoplasm | Metastatic Neoplasm

China
Ohio State University Comprehensive Cancer Center
Novartis Pharmaceuticals; National Comprehensive Cancer Network

Completed

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Unknown

Detection of CTCs in Stage III Rectal Cancer Patients Undergoing Neoadjuvant Therapy

Rectal Neoplasms | Circulating Tumor Cells

China
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Rectal Adenocarcinoma

United States
First Affiliated Hospital of Guangxi Medical University

Recruiting

The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer

Rectal Cancer | Rectal Cancer Stage II | Rectal Cancer Stage III

China
Jules Bordet Institute

Recruiting

Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer (REGINA)

Rectal Cancer Stage II | Rectal Cancer Stage III

Belgium, France
Carol Davila University of Medicine and Pharmacy

Recruiting

Endoscopic Submucosal Dissection Registry (ESDREG)

Neoplasm, Colorectal | Neoplasm, Stomach | Neoplasm, Esophagus | Neoplasm, Duodenal

Romania
Washington University School of Medicine

Recruiting

Ultrasound and Photoacoustic Imaging of Colon and Rectal Tumor Tissue

Rectal Cancer

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Is There a Link Between Anatomical Markers of Surgical Difficulty and Incapacity to Reverse Stoma After Low Rectal Cancer Surgery? (persist stomie)

Rectal Surgery

France
UNC Lineberger Comprehensive Cancer Center

Completed

PET/MRI as a Predictor of Response to Pre-op Chemoradiation in Resectable Rectal Cancer: a Pilot Study

Rectal Carcinoma

United States
University of California, San Francisco

Terminated

Evaluation of Rectal Cancer Treatment Response Using PET/MRI (Rectal PET/MRI)

Rectal Adenocarcinoma

United States
IHU Strasbourg

Terminated

Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology (TRaMA)

Rectal Cancer | Rectal Adenocarcinoma

France
National Cancer Institute (NCI)

Terminated

Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage II Rectal Cancer AJCC v8 | Locally Advanced Rectal Carcinoma

United States
City of Hope Medical Center

Withdrawn

Laparoscopic Surgery or Robotic-Assisted Laparoscopic Surgery in Treating Patients With Rectal Cancer That Can Be Removed By Surgery

Recurrent Rectal Cancer | Stage I Rectal Cancer | Stage II Rectal Cancer | Stage III Rectal Cancer
Peking University Third Hospital

Recruiting

Application of MRI in Identifying Myelosuppression Risk of Neoadjuvant Chemoradiotherapy for Rectal Cancer

Rectal Cancer Stage II | Rectal Cancer Stage III

China
Prof. Dr. med. Claus Rödel
Johann Wolfgang Goethe University Hospital; Deutsche Krebshilfe e.V., Bonn...

Completed

Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer (CAOAROAIO-12)

Rectal Neoplasms | Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
Tampere University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Not yet recruiting

Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer (NORPPA-1)

Rectal Cancer | Rectal Adenocarcinoma

Finland, Estonia
Liz-Anne Lewsley
AstraZeneca; NHS Greater Glasgow and Clyde; University of Glasgow

Not yet recruiting

A Trial of Durvalumab (MEDI 4736) in Combination With Extended Neoadjuvant Regimens in Rectal Cancer (PRIME-RT)

Rectal Cancer | Rectal Neoplasms | Rectal Adenocarcinoma
Southwest Hospital, China

Recruiting

PR in Endoscopic LAR for Rectal Cancer

Rectal Carcinoma

China
European Association for Endoscopic Surgery

Completed

Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer (NERATEM)

RECTAL CANCER

Italy
National Cancer Center, China

Not yet recruiting

Sentinel Lymph Node Biopsy in Rectal Cancer

Rectal Cancer Stage III | Rectal Cancer Stage IV

China
University Hospital Tuebingen

Recruiting

Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy. (CAO/ARO/AIO-16)

Rectal Cancer | Rectal Neoplasms | Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
AUSL Romagna Rimini
AstraZeneca; Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori

Recruiting

Capecitabine Plus Concomitant Radiation Therapy Followed by Durvalumab as Preoperative Treatment in Rectal Cancer (PANDORA)

RECTAL CANCER

Italy
Radboud University Medical Center

Completed

Transanal Endoscopic Microsurgery (TEM) After Radiochemotherapy for Rectal Cancer (CARTS)

Rectal Tumour

Netherlands
Hospital Universitario Virgen de la Arrixaca

Completed

Prospective Randomised Study Comparing Laparoscopic Versus Open Surgery in Patients With Rectal Cancer

RECTAL CANCER
Institute of Oncology Ljubljana

Unknown

IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment (BISER)

Rectal Carcinoma

Slovenia
National University Hospital, Singapore
Tan Tock Seng Hospital

Unknown

Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer

Rectal Cancers.

Singapore
National Cancer Institute (NCI)

Completed

Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer

Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v7 | Stage II Rectal Cancer AJCC v7

United States
European Institute of Oncology

Recruiting

Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens

Anal Cancer | High-Risk Cancer | Anal Intraepithelial Neoplasia 2 | Anal Intraepithelial Neoplasia 1

Italy
National Cancer Institute (NCI)
NRG Oncology

Completed

Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer

Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v7 | Stage II Rectal Cancer AJCC v7

United States, Puerto Rico
Sun Yat-sen University

Active, not recruiting

TNT to Increase the Clinical Complete Response Rate for Distal LARC (TESS)

Chemoradiation | Rectal Cancer | Rectal Cancer Stage II | Rectal Cancer Stage III

China
Sir Run Run Shaw Hospital

Recruiting

Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer (mRCAT)

Low Rectal Cancer

China
University of Rochester

Active, not recruiting

Neoadjuvant FOLFOX Therapy With Short Course Radiation and Active Surveillance in Locally Advanced Rectal Cancer

Advanced Rectal Cancer

United States
Asan Medical Center

Completed

Preoperative CRT With Capecitabine ± Temozolomide in Patients With LARC

Advanced Rectal Cancer

Korea, Republic of
Centre Georges Francois Leclerc

Completed

Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers (RADICAL)

Advanced Rectal Cancers

France
University of Florida
National Cancer Institute (NCI)

Completed

The United States Healthy Living Study

Colo-rectal Cancer

United States
Nanfang Hospital of Southern Medical University

Unknown

The Diagnosis of Invasive Depth of Early Rectal Cancer

Early Rectal Cancer
Mansoura University

Unknown

Long Term Outcomes After Laparoscopic Intersphincteric Resection With Total Mesorectal Excision for Low Rectal Cancer. (ISR-TME)

Low Rectal Cancer
Fox Chase Cancer Center
National Cancer Institute (NCI)

Terminated

Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Liver Metastases | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer and other conditions

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Recruiting

Assessment of Patients' Quality of Sexual Life After Anal Cancer Treatment (SEQUOIA)

Anxiety | Anal Cancer | HPV | Sexuality | Psychologic Stress

France
Centre Francois Baclesse
Accuray Incorporated

Active, not recruiting

Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life (CANAL-IMRT-01)

Locally Advanced Anal Canal Cancer

France
Assiut University

Not yet recruiting

Comparison of Ultrasound-guided Erector Spinae Plane Block and Transmuscular Quadratus Lumborum Block

Colo-rectal Cancer
QIAGEN Gaithersburg, Inc
Amgen

Recruiting

Therascreen® KRAS RGQ PCR Kit

Colo-rectal Cancer

United Kingdom
National Cancer Institute, Egypt

Recruiting

Reversal of a Defunctioning Ileostomy 3 Weeks After the Index Operation, RCT

Colo-rectal Cancer

Egypt
Seoul National University Hospital

Recruiting

Comparison Between Tailored Surgery Versus Total Mesorectal Excision in ycT2-3N0M0

Rectal Cancer, Adenocarcinoma

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts

Colo-rectal Cancer

China
Shanghai Zhongshan Hospital

Recruiting

Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer

Colo-rectal Cancer

China
Niguarda Hospital

Completed

Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer (NO-CUT)

Colo-rectal Cancer

Italy
George Albert Fisher
Bristol-Myers Squibb

Terminated

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

Rectal Cancer | Colo-rectal Cancer

United States
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

A Prospective Phase II Randomized Clinical Trial of Preoperative Chemotherapy Combined With Short-course Radiotherapy Versus Conventional Neo-adjuvant Therapy for Locally Advanced Rectal Cancer Implemented by MDT

Rectal Cancer, Radiotherapy

Clinical Trials on Neoplasms, Rectal

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