Clinical Trials on Opioid Agonist Treatment

Total 3964 results

Orexo AB
Worldwide Clinical Trials

Completed

Multi-Center, Open-Label, 24-Week Study of OX219 Safety and Efficacy for Maintenance Treatment of Opioid Dependence

Opioid Dependence, on Agonist Therapy

United States
Mundipharma Research Limited

Completed

Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution

Opioid Substitution Treatment
Orexo AB
Worldwide Clinical Trials

Completed

Efficacy of BNX Sublingual Tablets Versus BNX Sublingual Film for Treatment of Opioid-Dependent Adults (ISTART)

Opioid Dependence, on Agonist Therapy

United States
U.S. Army Medical Research and Development Command

Completed

Study to Evaluate the Safety of a New Oxime, MMB4 DIMETHANESULFONATE (DMS) (MMB4(DMS))

Treatment Against the Lethal Effects of Nerve Agent Intoxication

United States
University of Maryland, College Park
University of Maryland, Baltimore; Henry Ford Health System

Recruiting

Peer Activate: Trial of Peer-Delivered Behavioral Activation for Methadone Adherence (HEAL Together)

Substance-Related Disorders | Opioid Use Disorder | Treatment Adherence | Opioid Use | Retention in Care | Opioid Addiction | Opioid Medication Assisted Treatment

United States
University Hospital, Angers

Unknown

Content and Expectations of Consultations of Patients With Opioid Substitution Treatment Considered as Stabilized: Cross-Testimonials Doctors - Patients (MSOSuiStab) (MSOSuiStab)

Opioid Substitution Treatment

France
Yale University

Completed

The Prevalence of HIV Drug Resistance and Transmission Risk in Opioid Agonist Treatment

HIV Infections | Opioid Dependence | HIV Positive | Opioid Agonist Treatment

United States
MetroHealth Medical Center

Completed

ICE T for Post GYN Surgery Pain

Opioid Substitution Treatment

United States
Karen Derefinko, PhD
University of New Mexico; University of Memphis

Completed

SMART Trial Efficacy Study

Opioid Dependence | Treatment Adherence | Opioid-use Disorder

United States
VA Office of Research and Development

Completed

Consortium to Disseminate and Understand Implementation of Opioid Use Disorder Treatment (CONDUIT)

Opioid Medication Assisted Treatment

United States
WellSpan Health
Ambu A/S; York Opioid Collaborative, Pennsylvania

Terminated

The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis

Pregnancy Related | Cesarean Section | Medication Assisted Treatment | Opioid Dependence | Opioid Use | Opioid Abuse | Opioid-use Disorder | Infusion Catheter, Wound | Lidopatch | Ambu ACTion

United States
National Development and Research Institutes, Inc.
Treatment Alternatives for Safe Communities

Unknown

Facilitating MAT Acceptance & Implementation in Problem Solving & Felony Courts

Improving Treatment for Opioid Use Disorder in Courts

United States
University of Vermont
National Institute on Drug Abuse (NIDA); Substance Abuse and Mental Health...

Completed

Start Treatment and Recovery for Opioid Use Disorder (STAR)

Opioid-use Disorder | Mental Disorder | Opioid Medication Assisted Treatment

United States
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Maryland, Baltimore; Weill...

Recruiting

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention (PRISM)

Substance-Related Disorders | Treatment Adherence | Retention in Care | Opioid Medication Assisted Treatment | Polysubstance Addiction

United States
University Hospital, Grenoble

Completed

Beta2-mimetic and Central Nervous System (BETACTIV)

Adrenergic Beta-2 Agonist Effect | Albuterol Effect

France
University of California, San Francisco
San Francisco Veterans Affairs Medical Center

Completed

Methadone Oxytocin Option (MOO)

Opioid Dependence | Substance Abuse | Methadone Treatment

United States
University of Alabama, Tuscaloosa
University of Alabama at Birmingham; Tuscaloosa Veterans Affairs Medical Center

Completed

Minds and Mentors Program (MiMP)- R61 (MiMP)

Substance Use Disorders | Medication Assisted Treatment | Opioid-use Disorder

United States
University of Vermont Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Incentive-based Smoking Cessation for Methadone Patients

Cigarette Smoking Among Patients Currently Receiving Methadone or Buprenorphine Treatment for Opioid Dependence

United States
Rhode Island Hospital
National Institute on Drug Abuse (NIDA)

Completed

Digital Health Intervention to Support Opioid Use Disorder Treatment (iENDURE)

Opioid Use Disorder | Treatment Adherence

United States
King's College London
NHS Tayside; Bangor University; South London and Maudsley NHS Foundation Trust; Greater Manchester Mental Health NHS Foundation Trust and other collaborators

Completed

Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO)

Opiate Substitution Treatment

United Kingdom
Kaiser Permanente
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

Opiate Substitution Treatment

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

Opioid Sensitivity | Individual Difference | Abuse Opioids

United States
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Use of a GLP-1R Agonist to Treat Opioid Use Disorder

Opioid-Related Disorders | Opiate Substitution Treatment

United States
Bioroma

Unknown

Clomiphene Citrate Plus Gonadotropins and GnRH Antagonist Versus Flexible GnRH Antagonist Protocol Versus Microdose GnRH Agonist Protocol in Poor Responders Undergoing IVF

GnRH Antagonist | IVF | Poor Responders | Clomiphene Citrate | GnRH Agonist

Italy
Lifespan
National Institute on Drug Abuse (NIDA)

Recruiting

Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: Qualitative Interviews

Opioid Use Disorder | Treatment Adherence and Compliance | Criminal Justice

United States
University of Aarhus

Completed

Predictive Markers of the Effects of Opioid Therapy (ABILITY)

Chronic Pain | Opioid Analgesic Treatment Response

Belgium, Denmark, Slovenia
Assiut University

Not yet recruiting

Safety of Oral Thrombopoietin Receptor Agonist in Pediatric Chronic ITP

Thrombopoietin Receptor Agonist
Centre hospitalier de l'Université de Montréal...
Pfizer

Completed

Desvenlafaxine in Opioid-Dependent Patients

Depression | Opioid Dependence | Methadone Treatment

Canada
University of Alabama, Tuscaloosa
University of Alabama at Birmingham; Tuscaloosa Veterans Affairs Medical Center and other collaborators

Recruiting

Minds and Mentors Program- R33 (MiMP)

Opioid Use Disorder | Substance Use Disorders | Medication Assisted Treatment

United States
University of Maryland, College Park
University of Maryland, Baltimore; National Center for Complementary and Integrative...

Completed

Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase (HEAL Together)

Substance Use | Substance Use Disorders | Opioid-use Disorder | Retention in Care | Methadone Treatment | Peer Delivered | Medication for Opioid Use Disorder (MOUD) | Behavioral Activation

United States
University of Michigan
US Department of Veterans Affairs; National Center for Complementary and Integrative...

Active, not recruiting

Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes (Persist)

Chronic Pain | Medication Assisted Treatment | Opioid-use Disorder

United States
M. Eugenia Socias
Canadian Institutes of Health Research (CIHR); Mayne Pharma International Pty... and other collaborators

Terminated

Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder (pRESTO)

Opioid-Related Disorders | Opiate Substitution Treatment | Morphine | Fentanyl | Methadone

Canada
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Evaluation of a Computerized Opioid Overdose Prevention Program

Treatment as Usual | Computer + Fluency | Computer Only

United States
Haukeland University Hospital
University of Bergen; Helse Stavanger HF; Helse Vest; Forskningsrådet; Folkehelse... and other collaborators

Active, not recruiting

Integrated Treatment of Hepatitis C Virus Infection (INTRO-HCV)

Hepatitis C, Chronic | Opioid Dependence, on Agonist Therapy

Norway
NYU Langone Health
National Institutes of Health (NIH)

Recruiting

ED Observation for Opioid Use Disorder

Opiod Use Disorder

United States
Analgesic Solutions

Unknown

Determining Genetic Biomarkers Predictive of the Development of Prescription Opioid Addiction

Usage of Prescription Opioids

United States
University of Chicago
Agency for Healthcare Research and Quality (AHRQ); ACCESS Community Health...

Active, not recruiting

I-COPE Study: Opioid Use and Pain Management in Older Adults (I-COPE)

Chronic Pain | Opioid-use Disorder | Opioids

United States
Shaare Zedek Medical Center

Active, not recruiting

GnRH Agonist for Luteal Phase Support.

Use of GnRH Agonist Alone for Luteal Phase Support in Fresh IVF Cycles

Israel
St. Louis University

Completed

A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries (Opioids)

Postoperative Pain | Orthopedic Disorder | Opioid Use | Narcotic Use | Narcotic Abuse | Analgesic Drug Dependence | Opioids; Harmful Use | Opioid Abuse, Uncomplicated

United States
Yale University
National Institutes of Health (NIH)

Recruiting

Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population (IMANI U)

Substance Use | Medication Assisted Treatment | Opioid Use | Mental Health Issue

United States
University of Pennsylvania
National Institute of Drug Abuse; The Wistar Institute; Ho Chi Minh City CDC; Institute...

Recruiting

Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1 (AMOHI-1)

Inflammation | Opioid-use Disorder | HIV-1-infection | Immune Activation | Buprenorphine | Methadone | Naltrexone | Antiretroviral Treatment

United States, Vietnam
University of New Mexico
National Institute on Drug Abuse (NIDA); Johns Hopkins University; Duke University and other collaborators

Recruiting

Pain and Opioids: Integrated Treatment In Veterans (POSITIVE)

Chronic Pain | Opioid-use Disorder | Opioids; Harmful Use

United States
Nycomed

Completed

Efficacy and Safety of FITpatch Compared to Standard Opioid Treatment in Cancer Pain (FT-015-IN)

Standard Opioid Analgesic Treatment of Cancer-related Chronic Pain.
Brigham and Women's Hospital

Enrolling by invitation

Kinematics of Ewing Amputees

Lower Extremity Amputation | Trans-Tibial Amputation | Traumatic Lower Extremity Amputation | Agonist-Antagonist Myoneural Interface

United States
AstraZeneca

Completed

Comparison of Bone Mineral Loss in Prostate Cancer Patients Who is Receiving GnRH Agonist and -Plus Anti-androgen Agent

GnRH Agonist Alone vs. GnRH Agonist Plus Anti-androgen Combination Treated Prostate Cancer Patients

Korea, Republic of
University of Pittsburgh

Terminated

Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty

Opioid Tolerance, Opioid Naive, Opioid Exposure

United States
National Health Research Institutes, Taiwan

Unknown

Methadone Maintenance Outcome Study in Taiwan: 5-year Follow-up

Quality of Life | Mortality | Heroin Dependence | Treatment Outcome | Sleep Impairment
University of Konstanz
Bielefeld University; Alexander von Humboldt Association

Completed

Prevention of Violence Against Children

Violence Against Children

Uganda
Tanta University

Completed

Effect of GnRH Agonist Treatment Protocols on Ovarian Reserve

Infertility | Intracytoplasmic Sperm Injection | Ovarian Reserve | GnRH Agonist

Egypt
University of Manitoba

Recruiting

Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy

Opioid Use | Pain, Chronic | Hyperalgesia | Opioids; Harmful Use

Canada

Clinical Trials on Opioid Agonist Treatment

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