Clinical Trials on Opioid Substitution Treatment

Total 3891 results

Mundipharma Research Limited

Completed

Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution

Opioid Substitution Treatment
University Hospital, Angers

Unknown

Content and Expectations of Consultations of Patients With Opioid Substitution Treatment Considered as Stabilized: Cross-Testimonials Doctors - Patients (MSOSuiStab) (MSOSuiStab)

Opioid Substitution Treatment

France
MetroHealth Medical Center

Completed

ICE T for Post GYN Surgery Pain

Opioid Substitution Treatment

United States
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Use of a GLP-1R Agonist to Treat Opioid Use Disorder

Opioid-Related Disorders | Opiate Substitution Treatment

United States
King's College London
NHS Tayside; Bangor University; South London and Maudsley NHS Foundation Trust; Greater Manchester Mental Health NHS Foundation Trust and other collaborators

Completed

Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO)

Opiate Substitution Treatment

United Kingdom
Kaiser Permanente
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

Opiate Substitution Treatment

United States
M. Eugenia Socias
Canadian Institutes of Health Research (CIHR); Mayne Pharma International Pty... and other collaborators

Terminated

Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder (pRESTO)

Opioid-Related Disorders | Opiate Substitution Treatment | Morphine | Fentanyl | Methadone

Canada
University of Arkansas

Enrolling by invitation

Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder

Opioid-Related Disorders | Magnetic Resonance Imaging | Mobile Applications | Opiate Substitution Treatment | Craving | Attentional Bias | Ecological Momentary Assessment

United States
University of Maryland, College Park
University of Maryland, Baltimore; Henry Ford Health System

Recruiting

Peer Activate: Trial of Peer-Delivered Behavioral Activation for Methadone Adherence (HEAL Together)

Substance-Related Disorders | Opioid Use Disorder | Treatment Adherence | Opioid Use | Retention in Care | Opioid Addiction | Opioid Medication Assisted Treatment

United States
Denver Health and Hospital Authority
Department of Health and Human Services

Active, not recruiting

Increasing Linkage to Family Planning Care for Individuals With Substance Use Disorder

Substance-Related Disorders | Opiate Substitution Treatment | Family Planning Services | Sexual Health

United States
Sheba Medical Center

Unknown

Prospective Trial to Evaluate Efficacy and Accuracy of a Portable Ultrasound Scanner for Non-Invasive Bladder Volume Measurement (BladderScan BVI3000) in Patients After Radical Cystectomy and Bladder Reconstruction

Bladder Substitution | Reconstructed Bladder

Israel
Karen Derefinko, PhD
University of New Mexico; University of Memphis

Completed

SMART Trial Efficacy Study

Opioid Dependence | Treatment Adherence | Opioid-use Disorder

United States
VA Office of Research and Development

Completed

Consortium to Disseminate and Understand Implementation of Opioid Use Disorder Treatment (CONDUIT)

Opioid Medication Assisted Treatment

United States
WellSpan Health
Ambu A/S; York Opioid Collaborative, Pennsylvania

Terminated

The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis

Pregnancy Related | Cesarean Section | Medication Assisted Treatment | Opioid Dependence | Opioid Use | Opioid Abuse | Opioid-use Disorder | Infusion Catheter, Wound | Lidopatch | Ambu ACTion

United States
National Development and Research Institutes, Inc.
Treatment Alternatives for Safe Communities

Unknown

Facilitating MAT Acceptance & Implementation in Problem Solving & Felony Courts

Improving Treatment for Opioid Use Disorder in Courts

United States
University of Vermont
National Institute on Drug Abuse (NIDA); Substance Abuse and Mental Health...

Completed

Start Treatment and Recovery for Opioid Use Disorder (STAR)

Opioid-use Disorder | Mental Disorder | Opioid Medication Assisted Treatment

United States
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Maryland, Baltimore; Weill...

Recruiting

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention (PRISM)

Substance-Related Disorders | Treatment Adherence | Retention in Care | Opioid Medication Assisted Treatment | Polysubstance Addiction

United States
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

A Multicenter Research on the Effects of Substitution of Hospital Ward Care From Medical Doctors to Physician Assistants

Substitution of Care

Netherlands
University of California, San Francisco
San Francisco Veterans Affairs Medical Center

Completed

Methadone Oxytocin Option (MOO)

Opioid Dependence | Substance Abuse | Methadone Treatment

United States
University of Alabama, Tuscaloosa
University of Alabama at Birmingham; Tuscaloosa Veterans Affairs Medical Center

Completed

Minds and Mentors Program (MiMP)- R61 (MiMP)

Substance Use Disorders | Medication Assisted Treatment | Opioid-use Disorder

United States
University of Vermont Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Incentive-based Smoking Cessation for Methadone Patients

Cigarette Smoking Among Patients Currently Receiving Methadone or Buprenorphine Treatment for Opioid Dependence

United States
Rhode Island Hospital
National Institute on Drug Abuse (NIDA)

Completed

Digital Health Intervention to Support Opioid Use Disorder Treatment (iENDURE)

Opioid Use Disorder | Treatment Adherence

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

Opioid Sensitivity | Individual Difference | Abuse Opioids

United States
Lifespan
National Institute on Drug Abuse (NIDA)

Recruiting

Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: Qualitative Interviews

Opioid Use Disorder | Treatment Adherence and Compliance | Criminal Justice

United States
University of Aarhus

Completed

Predictive Markers of the Effects of Opioid Therapy (ABILITY)

Chronic Pain | Opioid Analgesic Treatment Response

Belgium, Denmark, Slovenia
Centre hospitalier de l'Université de Montréal...
Pfizer

Completed

Desvenlafaxine in Opioid-Dependent Patients

Depression | Opioid Dependence | Methadone Treatment

Canada
University of Alabama, Tuscaloosa
University of Alabama at Birmingham; Tuscaloosa Veterans Affairs Medical Center and other collaborators

Recruiting

Minds and Mentors Program- R33 (MiMP)

Opioid Use Disorder | Substance Use Disorders | Medication Assisted Treatment

United States
University of Maryland, College Park
University of Maryland, Baltimore; National Center for Complementary and Integrative...

Completed

Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase (HEAL Together)

Substance Use | Substance Use Disorders | Opioid-use Disorder | Retention in Care | Methadone Treatment | Peer Delivered | Medication for Opioid Use Disorder (MOUD) | Behavioral Activation

United States
University of Michigan
US Department of Veterans Affairs; National Center for Complementary and Integrative...

Active, not recruiting

Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes (Persist)

Chronic Pain | Medication Assisted Treatment | Opioid-use Disorder

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Bruni® Training in OPHL Patients (BTLS)

Substitution Voice

Italy
Tomas Bata Hospital, Czech Republic
Faculty Hospital Kralovske Vinohrady

Recruiting

Oral Nano Vitamin D Supplementation Efficacy in Inflammatory Bowel Disease

Vitamin D Substitution

Czechia
Tel-Aviv Sourasky Medical Center

Unknown

Fecal Microbial Transplantation and Vedolizumab Treatment of Crohn's Disease

Crohn Disease | Microbial Substitution

Israel
Faculty Hospital Kralovske Vinohrady
Brno University Hospital; Nemocnice T.Bati, Zlin

Unknown

Vitamin D Substitution During Winter Time

Vitamin D Substitution

Czech Republic
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Evaluation of a Computerized Opioid Overdose Prevention Program

Treatment as Usual | Computer + Fluency | Computer Only

United States
Fresenius Kabi Japan

Completed

Study to Obtain Volume Effect and Safety Data on 6 % Hydroxyethyl Starch 130/0.4 in Pediatric and Adult Patients Undergoing Major Elective Surgery

Plasma Volume Substitution (Hypovolemia) Including Massive Hemorrhage

Japan
NYU Langone Health
National Institutes of Health (NIH)

Recruiting

ED Observation for Opioid Use Disorder

Opiod Use Disorder

United States
Analgesic Solutions

Unknown

Determining Genetic Biomarkers Predictive of the Development of Prescription Opioid Addiction

Usage of Prescription Opioids

United States
S.Eugenio Hospital
Domenico Spoletini, M.D. PhD; Michele Grieco, M.D.; Rosa Marcellinaro, M.D PhD; Andrea Mingoli, M.D. PhD and other collaborators

Completed

Microbiota Implementation to Reduce Anastomotic Colorectal Leaks (MIRACLe) (MIRACLe)

Colorectal Cancer | Surgery | Anastomotic Leak | Microbial Substitution | LAP

Italy
University of Chicago
Agency for Healthcare Research and Quality (AHRQ); ACCESS Community Health...

Active, not recruiting

I-COPE Study: Opioid Use and Pain Management in Older Adults (I-COPE)

Chronic Pain | Opioid-use Disorder | Opioids

United States
St. Louis University

Completed

A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries (Opioids)

Postoperative Pain | Orthopedic Disorder | Opioid Use | Narcotic Use | Narcotic Abuse | Analgesic Drug Dependence | Opioids; Harmful Use | Opioid Abuse, Uncomplicated

United States
Yale University
National Institutes of Health (NIH)

Recruiting

Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population (IMANI U)

Substance Use | Medication Assisted Treatment | Opioid Use | Mental Health Issue

United States
University of Pennsylvania
National Institute of Drug Abuse; The Wistar Institute; Ho Chi Minh City CDC; Institute...

Recruiting

Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1 (AMOHI-1)

Inflammation | Opioid-use Disorder | HIV-1-infection | Immune Activation | Buprenorphine | Methadone | Naltrexone | Antiretroviral Treatment

United States, Vietnam
University of New Mexico
National Institute on Drug Abuse (NIDA); Johns Hopkins University; Duke University and other collaborators

Recruiting

Pain and Opioids: Integrated Treatment In Veterans (POSITIVE)

Chronic Pain | Opioid-use Disorder | Opioids; Harmful Use

United States
Nycomed

Completed

Efficacy and Safety of FITpatch Compared to Standard Opioid Treatment in Cancer Pain (FT-015-IN)

Standard Opioid Analgesic Treatment of Cancer-related Chronic Pain.
National Taipei University of Nursing and Health...

Recruiting

The Effects of Exercise and Probiotics on Dysmenorrhea and Microbiome

Inflammation | Dysmenorrhea | Microbial Substitution

Taiwan
University of Pittsburgh

Terminated

Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty

Opioid Tolerance, Opioid Naive, Opioid Exposure

United States
National Health Research Institutes, Taiwan

Unknown

Methadone Maintenance Outcome Study in Taiwan: 5-year Follow-up

Quality of Life | Mortality | Heroin Dependence | Treatment Outcome | Sleep Impairment
University of Manitoba

Recruiting

Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy

Opioid Use | Pain, Chronic | Hyperalgesia | Opioids; Harmful Use

Canada
Medical University of Warsaw

Completed

Lidocaine VS Hemodynamic, Metabolic and Hormonal Response

Pneumoperitoneum | Acute Appendicitis | Opioid Consumption | Hemodynamic Response | Complication of Treatment

Poland
April M Young
National Institute on Drug Abuse (NIDA)

Recruiting

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Sexually Transmitted Diseases | Opioid-Related Disorders | Substance Abuse | Drug Overdose | Opiate Substitution Treatment | Human Immunodeficiency Virus (HIV) | Hepatitis C (HCV) | Intravenous Drug Usage

United States

Clinical Trials on Opioid Substitution Treatment

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