Clinical Trials on Oral Cavity Cancer

Total 52450 results

University of Washington
Blaze Bioscience Inc.

Recruiting

A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

Stage III Lip and Oral Cavity Cancer AJCC v8 | Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Stage IVA Lip and Oral Cavity Cancer AJCC v8

United States
Ohio State University Comprehensive Cancer Center

Completed

Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care

Tongue Cancer | Lip and Oral Cavity Squamous Cell Carcinoma | Oral Cavity Verrucous Carcinoma | Stage 0 Lip and Oral Cavity Cancer

United States
National Cancer Institute (NCI)

Completed

Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx

Lip and Oral Cavity Cancer | Oropharyngeal Cancer | Tongue Cancer | Stage 0 Lip and Oral Cavity Cancer | Stage 0 Oropharyngeal Cancer

United States
National Cancer Institute (NCI)

Completed

Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia

Lip and Oral Cavity Cancer | Oropharyngeal Cancer | Tongue Cancer | Oral Leukoplakia

United States
Medical University of South Carolina
Bristol-Myers Squibb

Completed

Trial of Nivolumab as a Novel Neoadjuvant Pre-Surgical Therapy for Locally Advanced Oral Cavity Cancer

Oral Cavity SCC

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Verrucous Carcinoma of the Larynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Recurrent Adenoid... and other conditions

United States
University Hospital, Basel, Switzerland

Recruiting

Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction

Oral Cavity Defect | Oropharynx Defect

Switzerland
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Locally Advanced Resectable Oral Cavity Squamous Cell Cancer

Italy
Centre Hospitalier Universitaire Dijon

Completed

Spectrometry of Cancerous Lesions of the Oral Cavity (SpectrORL1)

Cancerous Lesions of the Oral Cavity

France
National Cancer Institute (NCI)
Dana-Farber Cancer Institute

Withdrawn

ONYX-015 With Cisplatin and Fluorouracil in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer | Lip and Oral Cavity Cancer | Oropharyngeal Cancer

United States
Dow University of Health Sciences

Completed

Behavior Changing Intervention for Smokeless Tobacco and Betel Quid Use in Adolescents

Oral Cavity Carcinoma

Pakistan
University of British Columbia

Recruiting

Mandibular Reconstruction Preplanning (ViPMR) (ViPMR)

Oral Cancer | Oral Cavity Cancer

Canada
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Withdrawn

Hypofractionated Radiation Therapy Followed by Surgery in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity

Tongue Cancer | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Verrucous Carcinoma of the Oral Cavity | Stage IVA Verrucous Carcinoma of the Oral Cavity | Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVB Verrucous Carcinoma of the Oral Cavity | Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity

United States
Memorial Sloan Kettering Cancer Center
Monash University

Completed

Quality of Life and Development of Measures in Patients With Cancer of the Oral Cavity

Cancer of the Oral Cavity

United States
Ohio State University Comprehensive Cancer Center

Completed

Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors

Tongue Cancer | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous Carcinoma of the Oral Cavity | Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage II Squamous Cell Carcinoma of the Oropharynx | Stage... and other conditions

United States
Dokuz Eylul University

Completed

The Effect of Oral Care Protocol on Prevention of Oral Mucositis in Pediatric Cancer Patients

Mucositis | Pediatric Cancer | Oral Cavity

Turkey
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the Oral Cavity

Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Oropharynx | Stage I Verrucous... and other conditions

United States
University of British Columbia

Recruiting

Radial Forearm Donor Site Closure

Oral Cancer | Oral Cavity Cancer | Donor Site Complication

Canada
Ohio State University Comprehensive Cancer Center

Completed

Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.

Tongue Cancer | Salivary Gland Squamous Cell Carcinoma | Stage I Salivary Gland Cancer | Stage I Squamous Cell Carcinoma of the Hypopharynx | Stage I Squamous Cell Carcinoma of the Larynx | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Nasopharynx and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Buccal Mucosa Squamous Cell Carcinoma | Floor of Mouth Squamous Cell Carcinoma | Gingival Squamous Cell Carcinoma | Hard Palate Squamous Cell Carcinoma | Lip Squamous Cell... and other conditions

United States, Canada
Emory University
Bristol-Myers Squibb; Brooklyn ImmunoTherapeutics, LLC

Withdrawn

Nivolumab & IRX-2 With Surgery for Resectable Stage III-IVA Oral Cavity Cancer or HPV-Positive Oropharyngeal Cancer

Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma | Stage II Oral Cavity Squamous Cell...

United States
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Phase I/II Study of Postoperative Adjuvant Chemoradiation for Advanced-Stage Cutaneous Squamous Cell Carcinoma of the Head and Neck (cSCCHN)

Squamous Cell Carcinoma of the Skin | Recurrent Skin Cancer | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVA Squamous Cell Carcinoma of the...

United States
University Health Network, Toronto

Completed

A Comparative Study of Ultrasound Versus CT Measurement of Tongue and Oral Cavity Size

Ultrasound Airway Imaging in Determining the Oral Cavity and Tongue Size

Canada
Wake Forest University Health Sciences

Terminated

Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

Stage I Adenoid Cystic Carcinoma of the Oral Cavity | Stage I Mucoepidermoid Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Hypopharynx | Stage I Squamous Cell Carcinoma of the Larynx | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Verrucous Carcinoma... and other conditions

United States
University Hospital, Montpellier

Recruiting

Sentinel. Ambulatory. Oral Cavity. Oropharynx (S.A.C.O) (SACO)

Cancer T1-N0 or T2-N0 of the Oral Cavity

France
Mayo Clinic
National Cancer Institute (NCI)

Completed

Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

Mucositis | Tongue Cancer | Oral Complications | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Verrucous Carcinoma of the Larynx | Recurrent... and other conditions

United States
Indrayani Hospital and Cancer Institute
Tata Capital Limited; Grant Medical Foundation Ruby hall Clinic

Completed

Adjuvant ChemoRadiotherapy Prior to Surgery in Stage IVa Oral Cancers

Squamous Cell Carcinoma of Oral Cavity

India
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma

Recurrent Salivary Gland Carcinoma | Stage IVA Major Salivary Gland Cancer AJCC v7 | Stage IVB Major Salivary Gland Cancer AJCC v7 | Stage IVC Major Salivary Gland Cancer AJCC v7 | Tongue Carcinoma | Salivary Gland Adenoid Cystic Carcinoma | Recurrent Oral Cavity Adenoid Cystic Carcinoma | Stage... and other conditions

United States, Canada
Medical College of Wisconsin
National Cancer Institute (NCI)

Active, not recruiting

Pharmacokinetic (PK) Analysis of Antitumor B in Patients With Oral Cancer

Squamous Cell Carcinoma of the Oral Cavity

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck Lesions

Precancerous Condition | Lip and Oral Cavity Squamous Cell Carcinoma | Oral Cavity Verrucous Carcinoma

United States
Shanghai Jiao Tong University School of Medicine

Completed

TPF Induction Chemotherapy for Locally Advanced and Resectable Oral Squamous Cell Carcinoma

Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage III Oral Cavity Squamous Cell Carcinoma

China
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States
Ryan J. Halter
Dartmouth College

Not yet recruiting

RetracTOR/ Retractor for Image Guided Trans-Oral Surgery

Oral Cavity Disease

United States
University of Campinas, Brazil
Texas Tech University

Completed

Microneedle Pretreatment as a Strategy to Improve the Effectiveness of Topical Anesthetics Formulations

Oral Cavity Disease

Brazil
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

Head and Neck Cancer | Squamous Cell Carcinoma (SCC) of the Oral Cavity

United States
National Cancer Institute (NCI)

Completed

Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Oral Cavity Verrucous Carcinoma | Tongue... and other conditions

United States
Oslo University Hospital
Oslo Metropolitan University

Recruiting

Radiotherapy of Head and Neck Cancer Using an Intraoral Stent

Oral Cavity Cancer | Sinonasal Cancer

Norway
The Clatterbridge Cancer Centre NHS Foundation...
Bristol-Myers Squibb; University of Liverpool

Active, not recruiting

CA209-891: Neoadjuvant and Adjuvant Nivolumab as Immune Checkpoint Inhibition in Oral Cavity Cancer (NICO)

Squamous Cell Carcinoma of the Oral Cavity

United Kingdom
National Cancer Institute (NCI)
Southwest Oncology Group

Completed

Bortezomib Followed by the Addition of Doxorubicin at Disease Progression in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma (Cancer) of the Head and Neck

Recurrent Salivary Gland Cancer | Recurrent Adenoid Cystic Carcinoma of the Oral Cavity | Stage III Adenoid Cystic Carcinoma of the Oral Cavity | Stage III Salivary Gland Cancer | Stage IV Adenoid Cystic Carcinoma of the Oral Cavity | Stage IV Salivary Gland Cancer | Salivary Gland Adenoid Cystic...

United States
National Cancer Institute (NCI)

Active, not recruiting

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

Hyperplasia | Oral Cavity Carcinoma | Oral Leukoplakia | Erythroplakia

United States, Canada
Alpha Tau Medical LTD.

Recruiting

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT)

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Italy
Alpha Tau Medical LTD.

Active, not recruiting

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT)

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Israel
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab in Treating Patients With High Risk Oral Intraepithelial Neoplasia

Oral Cavity Carcinoma | Oral Intraepithelial Neoplasia

United States
National Cancer Institute (NCI)

Completed

Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer (ADCC)

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders

Dysplasia | Premalignant Lesion | Lip and Oral Cavity Carcinoma | Oral Disorder

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer

Stage I Oral Cavity Squamous Cell Carcinoma | Stage II Oral Cavity Squamous Cell Carcinoma

United States
Alpha Tau Medical LTD.

Recruiting

Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

Skin Cancer | Mucosal Neoplasm of Oral Cavity | Soft Tissue Neoplasm

Israel

Clinical Trials on Oral Cavity Cancer

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